Editorial: Insulin-like growth factor I receptor signaling - Overlapping or redundant pathways?

Endocrinology

Volumn 141, Issue 4, 2000, Pages 1287-1288

  Leroith, D ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; RAF PROTEIN; RAS PROTEIN; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TYROSINE;

APOPTOSIS; CELL PROLIFERATION; EDITORIAL; GENE MUTATION; INSULIN RESISTANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; ANIMAL; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; MUTATION; PHOSPHORYLATION; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0034457923     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.4.7475     Document Type: Editorial

References (20)

1. Molecular and cellular aspects of the insulin-like growth factor I receptor
2. Tumorigenic and mitogenic capacities are reduced in transfected fibroblasts expressing mutant insulin-like growth factor (IGF)-I receptors. The role of tyrosine residues 1250:1251, and 1316 in the carboxy-terminus of the IGF-I receptor
3. Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor
4. Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase- deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (αIR-3)
5. Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action
6. Effect of a mutation at tyrosine 950 of the insulin-like growth factor I receptor on the growth and transformation of cells
7. Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis
8. Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor
9. Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grbl0
10. Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracenular signal-regulated kinases by interleukin-4:implications for Ras activation by insulin
11. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
12. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
13. Regulation of neuronal survival by the serine-threonine protein kinase Akt
14. Mutations in the insulin receptor gene
15. Role of the carboxyl-terminal domains of the insulin and insulin-like growth factor I receptors in receptor function
16. Domains of the insulin-like growth factor I receptor required for the activation of extracellular signal-regulated kinases
17. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated prorein kinase pathways
18. 14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner
19. 14-3-3 Proteins interact with the insulin-like growth factor receptor but not the insulin receptor
20. 14-3-3β protein associates with insulin receptor substrate 1 and decreases insulin-stimulated phosphatidylinositol 3′-kinase activity in 3T3L1 adipocytes