Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects

Bone

Volumn 49, Issue 4, 2011, Pages 673-682

  Maeno, Takafumi ^a,b   Moriishi, Takeshi ^a   Yoshida, Carolina Andrea ^a   Komori, Hisato ^a   Kanatani, Naoko ^a   Izumi, Shin ichi ^a   Takaoka, Kunio ^b   Komori, Toshihisa ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone formation; Chondrocyte differentiation; Osteoblast differentiation; Prrx1 promoter; Runx2

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 1A1; COLLAGEN TYPE 2A1; HOMEODOMAIN PROTEIN; OSTEOPONTIN; PAIRED RELATED HOMEOBOX 1 PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CARTILAGE; CARTILAGE CELL; CARTILAGENOUS ANLAGEN; CELL DIFFERENTIATION; COL1A1 GENE; COL2A1 GENE; CONTROLLED STUDY; CRANIAL MESENCHYME CELL; CRANIAL SUTURE; CRANIOFACIAL SYNOSTOSIS; ECTOPIC BONE FORMATION; EMBRYO; ENCHONDRAL OSSIFICATION; FONTANEL; FOOT; GENE EXPRESSION; HAND; LIMB BUD; LIMB DEFECT; MANDIBLE; MESENCHYME CELL; MINERALIZATION; MOUSE; NONHUMAN; ONSET AGE; OSTEOBLAST; PATHOGENESIS; PROMOTER REGION; PROTEIN EXPRESSION; RUNX2 GENE; SKULL; SPP1 GENE; STERNUM; THORAX WALL; TRANSGENE;

ANIMALS; BONE AND BONES; CARTILAGE; CELL DIFFERENTIATION; CHONDROCYTES; CHORISTOMA; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CRANIOSYNOSTOSES; FACE; FLUORESCENCE; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; LIMB BUDS; MICE; MICE, TRANSGENIC; OSTEOBLASTS; OSTEOGENESIS; SKULL; X-RAY MICROTOMOGRAPHY;

EID: 80052290185     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.07.023     Document Type: Article

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