Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity

Molecular and Cellular Proteomics

Volumn 11, Issue 12, 2012, Pages 1898-1912

  Thomé, Carolina H ^a,b   Dos Santos, Guilherme A ^a,c   Ferreira, Germano A ^a,c   Scheucher, Priscila S ^a   Izumi, Clarice ^a,c   Leopoldino, Andreia M ^c   Simão, Ana Maria ^c   Ciancaglini, Pietro ^c   De Oliveira, Kleber T ^d   Chin, Alice ^e   Hanash, Samir M ^e   Falcão, Roberto P ^a,c   Rego, Eduardo M ^a,c   Greene, Lewis J ^a,c   Faça, Vitor M ^a,c  

^a Fundacao Hemocentro de Ribeirao   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^e Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

10 (OCTYLOXY) DECYL 2 (TRIMETHYLAMMONIUM) ETHYL PHOSPHATE; ADAPTOR PROTEIN; ANTILEUKEMIC AGENT; ARSENIC TRIOXIDE; CASPASE 3; ENDOPEPTIDASE CLP; GROWTH FACTOR; LAT2 PROTEIN; PERIFOSINE; PHOSPHOLIPID DERIVATIVE; PROTEASOME; PROTEIN KINASE B; RIBOSOME PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL FRACTIONATION; CELL PROLIFERATION; CHEMOSENSITIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIUM CELL; GENE SILENCING; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIPID RAFT; MOLECULARLY TARGETED THERAPY; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STABLE EXPRESSION; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARSENICALS; CASPASE 3; CELL LINE; CELL PROLIFERATION; CHOLESTEROL; ENZYME ACTIVATION; HUMANS; LEUKEMIA; MEMBRANE MICRODOMAINS; OXIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOLIPIDS; PHOSPHORYLCHOLINE; PROTEIN STRUCTURE, TERTIARY; PROTEOME; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84870699208     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M112.019661     Document Type: Article

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