Perifosine induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cell lines by blockade of Akt phosphorylation

Cytotechnology

Volumn 62, Issue 5, 2010, Pages 449-460

  Fei, Hong Rong ^a   Chen, Geng ^a   Wang, Jian Mei ^a   Wang, Feng Ze ^a  

^a TAISHAN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl 2; Caspase; Hepatocellular carcinoma; Perifosine; PI3 K Akt

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CISPLATIN; CYTOCHROME C; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PERIFOSINE; PROCASPASE 3; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; WESTERN BLOTTING;

EID: 78651521276     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-010-9299-4     Document Type: Article

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