메뉴 건너뛰기




Volumn 82, Issue 12, 2012, Pages 1284-1296

The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy

Author keywords

IgA; IgA deposition; IgA nephropathy

Indexed keywords

CALCIUM; CD71 ANTIGEN; CYTOKINE; IMMUNOGLOBULIN A1; IMMUNOGLOBULIN G; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 84870582926     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2012.192     Document Type: Article
Times cited : (77)

References (66)
  • 1
    • 17144461932 scopus 로고
    • [Intercapillary deposits of IgA-IgG]
    • Berger J, Hinglais N. [Intercapillary deposits of IgA-IgG]. J Urol Nephrol (Paris) 1968; 74: 694-695.
    • (1968) J Urol Nephrol (Paris) , vol.74 , pp. 694-695
    • Berger, J.1    Hinglais, N.2
  • 2
    • 0036789318 scopus 로고    scopus 로고
    • Pathogenic significance of IgA receptor interactions in IgA nephropathy
    • Monteiro RC, Moura IC, Launay P et al. Pathogenic significance of IgA receptor interactions in IgA nephropathy. Trends Mol Med 2002; 8: 464-468.
    • (2002) Trends Mol Med , vol.8 , pp. 464-468
    • Monteiro, R.C.1    Moura, I.C.2    Launay, P.3
  • 3
    • 29244472451 scopus 로고    scopus 로고
    • Factors predicting progression of IgA nephropathies
    • Coppo R, D'Amico G. Factors predicting progression of IgA nephropathies. J Nephrol 2005; 18: 503-512.
    • (2005) J Nephrol , vol.18 , pp. 503-512
    • Coppo, R.1    D'Amico, G.2
  • 5
    • 79952128105 scopus 로고    scopus 로고
    • Early change in proteinuria as a surrogate outcome in kidney disease progression: A systematic review of previous analyses and creation of a patient-level pooled dataset
    • Stoycheff N, Pandya K, Okparavero A et al. Early change in proteinuria as a surrogate outcome in kidney disease progression: a systematic review of previous analyses and creation of a patient-level pooled dataset. Nephrol Dial Transplant 2011; 26: 848-857.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 848-857
    • Stoycheff, N.1    Pandya, K.2    Okparavero, A.3
  • 6
    • 80053565042 scopus 로고    scopus 로고
    • Biomarkers in chronic kidney disease: A review
    • Fassett RG, Venuthurupalli SK, Gobe GC et al. Biomarkers in chronic kidney disease: a review. Kidney Int 2011; 80: 806-821.
    • (2011) Kidney Int , vol.80 , pp. 806-821
    • Fassett, R.G.1    Venuthurupalli, S.K.2    Gobe, G.C.3
  • 7
    • 0021024043 scopus 로고
    • Contractile properties of the glomerular mesangium
    • Kreisberg JI. Contractile properties of the glomerular mesangium. Fed Proc 1983; 42: 3053-3057.
    • (1983) Fed Proc , vol.42 , pp. 3053-3057
    • Kreisberg, J.I.1
  • 8
    • 0023767638 scopus 로고
    • The glomerular mesangium
    • Michael AF, Kim Y. The glomerular mesangium. Am J Kidney Dis 1988; 12: 393-396.
    • (1988) Am J Kidney Dis , vol.12 , pp. 393-396
    • Michael, A.F.1    Kim, Y.2
  • 9
    • 67449083682 scopus 로고    scopus 로고
    • The mesangial cell revisited: No cell is an island
    • Schlondorff D, Banas B. The mesangial cell revisited: no cell is an island. J Am Soc Nephrol 2009; 20: 1179-1187.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1179-1187
    • Schlondorff, D.1    Banas, B.2
  • 10
    • 10744224171 scopus 로고    scopus 로고
    • Glycosylation and size of IgA1 are essential for interaction with mesangial transferrin receptor in IgA nephropathy
    • Moura IC, Arcos-Fajardo M, Sadaka C et al. Glycosylation and size of IgA1 are essential for interaction with mesangial transferrin receptor in IgA nephropathy. J Am Soc Nephrol 2004; 15: 622-634.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 622-634
    • Moura, I.C.1    Arcos-Fajardo, M.2    Sadaka, C.3
  • 11
    • 33644789446 scopus 로고    scopus 로고
    • Engagement of transferrin receptor by polymeric IgA1: Evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy
    • Moura IC, Arcos-Fajardo M, Gdoura A et al. Engagement of transferrin receptor by polymeric IgA1: evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy. J Am Soc Nephrol 2005; 16: 2667-2676.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2667-2676
    • Moura, I.C.1    Arcos-Fajardo, M.2    Gdoura, A.3
  • 12
    • 3142590478 scopus 로고    scopus 로고
    • Scaffold proteins in mammalian MAP kinase cascades
    • Yoshioka K. Scaffold proteins in mammalian MAP kinase cascades. J Biochem 2004; 135: 657-661.
    • (2004) J Biochem , vol.135 , pp. 657-661
    • Yoshioka, K.1
  • 13
    • 3042523855 scopus 로고    scopus 로고
    • Activation of the extracellular-signal regulated protein kinase pathway in human glomerulopathies
    • Masaki T, Stambe C, Hill PA et al. Activation of the extracellular-signal regulated protein kinase pathway in human glomerulopathies. J Am Soc Nephrol 2004; 15: 1835-1843.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1835-1843
    • Masaki, T.1    Stambe, C.2    Hill, P.A.3
  • 14
    • 34548289084 scopus 로고    scopus 로고
    • MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma
    • Burgermeister E, Seger R. MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma. Cell Cycle 2007; 6: 1539-1548.
    • (2007) Cell Cycle , vol.6 , pp. 1539-1548
    • Burgermeister, E.1    Seger, R.2
  • 15
    • 68949218774 scopus 로고    scopus 로고
    • The Oxford classification of IgA nephropathy: Rationale, clinicopathological correlations, and classification
    • Cattran DC, Coppo R, Cook HT et al. The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Kidney Int 2009; 76: 534-545.
    • (2009) Kidney Int , vol.76 , pp. 534-545
    • Cattran, D.C.1    Coppo, R.2    Cook, H.T.3
  • 16
    • 38349136846 scopus 로고    scopus 로고
    • IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy
    • Novak J, Julian BA, Tomana M et al. IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy. Semin Nephrol 2008; 28: 78-87.
    • (2008) Semin Nephrol , vol.28 , pp. 78-87
    • Novak, J.1    Julian, B.A.2    Tomana, M.3
  • 17
    • 34248168090 scopus 로고    scopus 로고
    • The pathogenic role of IgA1 O-linked glycosylation in the pathogenesis of IgA nephropathy
    • Barratt J, Smith AC, Feehally J. The pathogenic role of IgA1 O-linked glycosylation in the pathogenesis of IgA nephropathy. Nephrology (Carlton) 2007; 12: 275-284.
    • (2007) Nephrology (Carlton) , vol.12 , pp. 275-284
    • Barratt, J.1    Smith, A.C.2    Feehally, J.3
  • 18
    • 79958856066 scopus 로고    scopus 로고
    • Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schonlein purpura nephritis
    • Kiryluk K, Moldoveanu Z, Sanders JT et al. Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schonlein purpura nephritis. Kidney Int 2011; 80: 79-87.
    • (2011) Kidney Int , vol.80 , pp. 79-87
    • Kiryluk, K.1    Moldoveanu, Z.2    Sanders, J.T.3
  • 19
    • 34249289769 scopus 로고    scopus 로고
    • Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels
    • Moldoveanu Z, Wyatt RJ, Lee JY et al. Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels. Kidney Int 2007; 71: 1148-1154.
    • (2007) Kidney Int , vol.71 , pp. 1148-1154
    • Moldoveanu, Z.1    Wyatt, R.J.2    Lee, J.Y.3
  • 20
    • 33846935486 scopus 로고    scopus 로고
    • Reactivities of Nacetylgalactosamine- specific lectins with human IgA1 proteins
    • Moore JS, Kulhavy R, Tomana M et al. Reactivities of Nacetylgalactosamine- specific lectins with human IgA1 proteins. Mol Immunol 2007; 44: 2598-2604.
    • (2007) Mol Immunol , vol.44 , pp. 2598-2604
    • Moore, J.S.1    Kulhavy, R.2    Tomana, M.3
  • 21
    • 67651006853 scopus 로고    scopus 로고
    • Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity
    • Suzuki H, Fan R, Zhang Z et al. Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity. J Clin Invest 2009; 119: 1668-1677.
    • (2009) J Clin Invest , vol.119 , pp. 1668-1677
    • Suzuki, H.1    Fan, R.2    Zhang, Z.3
  • 22
    • 0030836018 scopus 로고    scopus 로고
    • Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG
    • Tomana M, Matousovic K, Julian BA et al. Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG. Kidney Int 1997; 52: 509-516.
    • (1997) Kidney Int , vol.52 , pp. 509-516
    • Tomana, M.1    Matousovic, K.2    Julian, B.A.3
  • 23
    • 0032695357 scopus 로고    scopus 로고
    • Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies
    • Tomana M, Novak J, Julian BA et al. Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies. J Clin Invest 1999; 104: 73-81.
    • (1999) J Clin Invest , vol.104 , pp. 73-81
    • Tomana, M.1    Novak, J.2    Julian, B.A.3
  • 24
    • 12344284903 scopus 로고    scopus 로고
    • IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells
    • Novak J, Tomana M, Matousovic K et al. IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells. Kidney Int 2005; 67: 504-513.
    • (2005) Kidney Int , vol.67 , pp. 504-513
    • Novak, J.1    Tomana, M.2    Matousovic, K.3
  • 25
    • 33748063941 scopus 로고    scopus 로고
    • Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
    • McCubrey JA, Steelman LS, Abrams SL et al. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 2006; 46: 249-279.
    • (2006) Adv Enzyme Regul , vol.46 , pp. 249-279
    • McCubrey, J.A.1    Steelman, L.S.2    Abrams, S.L.3
  • 26
    • 68249093818 scopus 로고    scopus 로고
    • Targeting the phosphoinositide 3-kinase pathway in cancer
    • Liu P, Cheng H, Roberts TM et al. Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov 2009; 8: 627-644.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 627-644
    • Liu, P.1    Cheng, H.2    Roberts, T.M.3
  • 27
    • 0037458609 scopus 로고    scopus 로고
    • A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells
    • Komatsu N, Watanabe T, Uchida M et al. A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells. J Biol Chem 2003; 278: 6411-6419.
    • (2003) J Biol Chem , vol.278 , pp. 6411-6419
    • Komatsu, N.1    Watanabe, T.2    Uchida, M.3
  • 28
    • 0028172011 scopus 로고
    • Soluble IgA and IgG aggregates are catabolized by cultured rat mesangial cells and induce production of TNF-A and IL-6, and proliferation
    • Gomez-Guerrero C, Lopez-Armada MJ, Gonzalez E et al. Soluble IgA and IgG aggregates are catabolized by cultured rat mesangial cells and induce production of TNF-a and IL-6, and proliferation. J Immunol 1994; 153: 5247-5255.
    • (1994) J Immunol , vol.153 , pp. 5247-5255
    • Gomez-Guerrero, C.1    Lopez-Armada, M.J.2    Gonzalez, E.3
  • 29
    • 0037306594 scopus 로고    scopus 로고
    • Enhanced expression of the CD71 mesangial IgA1 receptor in Berger disease and Henoch-Schonlein nephritis: Association between CD71 expression and IgA deposits
    • Haddad E, Moura IC, Arcos-Fajardo M et al. Enhanced expression of the CD71 mesangial IgA1 receptor in Berger disease and Henoch-Schonlein nephritis: association between CD71 expression and IgA deposits. J Am Soc Nephrol 2003; 14: 327-337.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 327-337
    • Haddad, E.1    Moura, I.C.2    Arcos-Fajardo, M.3
  • 30
    • 33847060089 scopus 로고    scopus 로고
    • Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments
    • Lepelletier Y, Camara-Clayette V, Jin H et al. Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments. Cancer Res 2007; 67: 1145-1154.
    • (2007) Cancer Res , vol.67 , pp. 1145-1154
    • Lepelletier, Y.1    Camara-Clayette, V.2    Jin, H.3
  • 31
    • 10744221783 scopus 로고    scopus 로고
    • A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients
    • Moura IC, Lepelletier Y, Arnulf B et al. A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients. Blood 2004; 103: 1838-1845.
    • (2004) Blood , vol.103 , pp. 1838-1845
    • Moura, I.C.1    Lepelletier, Y.2    Arnulf, B.3
  • 32
    • 0032896766 scopus 로고    scopus 로고
    • ACE inhibition and ANG II receptor blockade improve glomerular size-selectivity in IgA nephropathy
    • Remuzzi A, Perico N, Sangalli F et al. ACE inhibition and ANG II receptor blockade improve glomerular size-selectivity in IgA nephropathy. Am J Physiol 1999; 276: F457-F466.
    • (1999) Am J Physiol , vol.276
    • Remuzzi, A.1    Perico, N.2    Sangalli, F.3
  • 35
    • 0033762699 scopus 로고    scopus 로고
    • IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23
    • Gharavi AG, Yan Y, Scolari F et al. IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23. Nat Genet 2000; 26: 354-357.
    • (2000) Nat Genet , vol.26 , pp. 354-357
    • Gharavi, A.G.1    Yan, Y.2    Scolari, F.3
  • 36
    • 77957254124 scopus 로고    scopus 로고
    • Genetic studies of IgA nephropathy: Past, present, and future
    • Kiryluk K, Julian BA, Wyatt RJ et al. Genetic studies of IgA nephropathy: past, present, and future. Pediatr Nephrol 2011; 25: 2257-2268.
    • (2011) Pediatr Nephrol , vol.25 , pp. 2257-2268
    • Kiryluk, K.1    Julian, B.A.2    Wyatt, R.J.3
  • 37
    • 79953224410 scopus 로고    scopus 로고
    • Genome-wide association study identifies susceptibility loci for IgA nephropathy
    • Gharavi AG, Kiryluk K, Choi M et al. Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nat Genet 2011; 43: 321-327.
    • (2011) Nat Genet , vol.43 , pp. 321-327
    • Gharavi, A.G.1    Kiryluk, K.2    Choi, M.3
  • 38
    • 33644913374 scopus 로고    scopus 로고
    • Differential role of MAPK signaling in human dendritic cell maturation and Th1/Th2 engagement
    • Nakahara T, Moroi Y, Uchi H et al. Differential role of MAPK signaling in human dendritic cell maturation and Th1/Th2 engagement. J Dermatol Sci 2006; 42: 1-11.
    • (2006) J Dermatol Sci , vol.42 , pp. 1-11
    • Nakahara, T.1    Moroi, Y.2    Uchi, H.3
  • 39
    • 0030589152 scopus 로고    scopus 로고
    • Initiation of acute phase response and synthesis of cytokines
    • Koj A. Initiation of acute phase response and synthesis of cytokines. Biochim Biophys Acta 1996; 1317: 84-94.
    • (1996) Biochim Biophys Acta , vol.1317 , pp. 84-94
    • Koj, A.1
  • 40
  • 41
    • 34249058409 scopus 로고    scopus 로고
    • Transferrin receptor engagement by polymeric IgA1 induces receptor expression and mesangial cell proliferation: Role in IgA nephropathy
    • Tamouza H, Vende F, Tiwari M et al. Transferrin receptor engagement by polymeric IgA1 induces receptor expression and mesangial cell proliferation: role in IgA nephropathy. Contrib Nephrol 2007; 157: 144-147.
    • (2007) Contrib Nephrol , vol.157 , pp. 144-147
    • Tamouza, H.1    Vende, F.2    Tiwari, M.3
  • 42
    • 34248205115 scopus 로고    scopus 로고
    • Mast cells and inflammatory kidney disease
    • Blank U, Essig M, Scandiuzzi L et al. Mast cells and inflammatory kidney disease. Immunol Rev 2007; 217: 79-95.
    • (2007) Immunol Rev , vol.217 , pp. 79-95
    • Blank, U.1    Essig, M.2    Scandiuzzi, L.3
  • 43
    • 21044458591 scopus 로고    scopus 로고
    • Mesangial cells and glomerular inflammation: From the pathogenesis to novel therapeutic approaches
    • Gomez-Guerrero C, Hernandez-Vargas P, Lopez-Franco O et al. Mesangial cells and glomerular inflammation: from the pathogenesis to novel therapeutic approaches. Curr Drug Targets Inflamm Allergy 2005; 4: 341-351.
    • (2005) Curr Drug Targets Inflamm Allergy , vol.4 , pp. 341-351
    • Gomez-Guerrero, C.1    Hernandez-Vargas, P.2    Lopez-Franco, O.3
  • 44
    • 0026842391 scopus 로고
    • The role of interstitial cells in the progression of renal diseases
    • .Muller GA, Markovic-Lipkovski J, Frank J et al. The role of interstitial cells in the progression of renal diseases. J Am Soc Nephrol 1992; 2: S198-S205.
    • (1992) J Am Soc Nephrol , vol.2
    • Muller, G.A.1    Markovic-Lipkovski, J.2    Frank, J.3
  • 45
    • 44949252210 scopus 로고    scopus 로고
    • Activation of podocytes by mesangialderived TNF-alpha: Glomerulo-podocytic communication in IgA nephropathy
    • Lai KN, Leung JC, Chan LY et al. Activation of podocytes by mesangialderived TNF-alpha: glomerulo-podocytic communication in IgA nephropathy. Am J Physiol Renal Physiol 2008; 294: F945-F955.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Lai, K.N.1    Leung, J.C.2    Chan, L.Y.3
  • 46
    • 0031252399 scopus 로고    scopus 로고
    • Interaction of IgA with Fc a receptors of human mesangial cells activates transcription factor nuclear factor-k B and induces expression and synthesis of monocyte chemoattractant protein-1, IL-8, and IFN-inducible protein 10
    • Duque N, Gomez-Guerrero C, Egido J. Interaction of IgA with Fc a receptors of human mesangial cells activates transcription factor nuclear factor-k B and induces expression and synthesis of monocyte chemoattractant protein-1, IL-8, and IFN-inducible protein 10. J Immunol 1997; 159: 3474-3482.
    • (1997) J Immunol , vol.159 , pp. 3474-3482
    • Duque, N.1    Gomez-Guerrero, C.2    Egido, J.3
  • 47
    • 4644250240 scopus 로고    scopus 로고
    • Mesangial expression of angiotensin II receptor in IgA nephropathy and its regulation by polymeric IgA1
    • Lai KN, Chan LY, Tang SC et al. Mesangial expression of angiotensin II receptor in IgA nephropathy and its regulation by polymeric IgA1. Kidney Int 2004; 66: 1403-1416.
    • (2004) Kidney Int , vol.66 , pp. 1403-1416
    • Lai, K.N.1    Chan, L.Y.2    Tang, S.C.3
  • 48
    • 0033515524 scopus 로고    scopus 로고
    • Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-k B transcription factors
    • Han Y, Runge MS, Brasier AR. Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-k B transcription factors. Circ Res 1999; 84: 695-703.
    • (1999) Circ Res , vol.84 , pp. 695-703
    • Han, Y.1    Runge, M.S.2    Brasier, A.R.3
  • 49
    • 0031858761 scopus 로고    scopus 로고
    • Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-k B activation and monocyte chemoattractant protein-1 synthesis
    • Ruiz-Ortega M, Bustos C, Hernandez-Presa MA et al. Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-k B activation and monocyte chemoattractant protein-1 synthesis. J Immunol 1998; 161: 430-439.
    • (1998) J Immunol , vol.161 , pp. 430-439
    • Ruiz-Ortega, M.1    Bustos, C.2    Hernandez-Presa, M.A.3
  • 50
    • 36049042645 scopus 로고    scopus 로고
    • Effects of p38 mitogen-activated protein kinase inhibition on blood pressure, renal hemodynamics, and renal vascular reactivity in normal and diabetic rats
    • Komers R, Schutzer W, Xue H et al. Effects of p38 mitogen-activated protein kinase inhibition on blood pressure, renal hemodynamics, and renal vascular reactivity in normal and diabetic rats. Transl Res 2007; 150: 343-349.
    • (2007) Transl Res , vol.150 , pp. 343-349
    • Komers, R.1    Schutzer, W.2    Xue, H.3
  • 51
    • 0041810638 scopus 로고    scopus 로고
    • The role of arterial hypertension in the progression of nondiabetic glomerular diseases
    • Ljutic D, Kes P. The role of arterial hypertension in the progression of nondiabetic glomerular diseases. Nephrol Dial Transplant 2003; 18(Suppl 5): v28-v30.
    • (2003) Nephrol Dial Transplant , vol.18 , Issue.SUPPL. 5
    • Ljutic, D.1    Kes, P.2
  • 52
    • 79551536252 scopus 로고    scopus 로고
    • Endothelial damage and regeneration: The role of the renin-angiotensin- aldosterone system
    • Becher UM, Endtmann C, Tiyerili V et al. Endothelial damage and regeneration: the role of the renin-angiotensin-aldosterone system. Curr Hypertens Rep 2011; 13: 86-92.
    • (2011) Curr Hypertens Rep , vol.13 , pp. 86-92
    • Becher, U.M.1    Endtmann, C.2    Tiyerili, V.3
  • 53
    • 0041464447 scopus 로고    scopus 로고
    • Angiotensin receptor subtypes in thin and muscular juxtamedullary efferent arterioles of rat kidney
    • Helou CM, Imbert-Teboul M, Doucet A et al. Angiotensin receptor subtypes in thin and muscular juxtamedullary efferent arterioles of rat kidney. Am J Physiol Renal Physiol 2003; 285: F507-F514.
    • (2003) Am J Physiol Renal Physiol , vol.285
    • Helou, C.M.1    Imbert-Teboul, M.2    Doucet, A.3
  • 54
    • 0038512403 scopus 로고    scopus 로고
    • Treatment of IgA nephropathy with ACE inhibitors: A randomized and controlled trial
    • Praga M, Gutierrez E, Gonzalez E et al. Treatment of IgA nephropathy with ACE inhibitors: a randomized and controlled trial. J Am Soc Nephrol 2003; 14: 1578-1583.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1578-1583
    • Praga, M.1    Gutierrez, E.2    Gonzalez, E.3
  • 55
    • 79952373965 scopus 로고    scopus 로고
    • Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
    • Haller H, Ito S, Izzo Jr JL et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med 2011; 364: 907-917.
    • (2011) N Engl J Med , vol.364 , pp. 907-917
    • Haller, H.1    Ito, S.2    Izzo Jr., J.L.3
  • 56
    • 0035920589 scopus 로고    scopus 로고
    • Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy
    • Moura IC, Centelles MN, Arcos-Fajardo M et al. Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy. J Exp Med 2001; 194: 417-425.
    • (2001) J Exp Med , vol.194 , pp. 417-425
    • Moura, I.C.1    Centelles, M.N.2    Arcos-Fajardo, M.3
  • 57
    • 34247394150 scopus 로고    scopus 로고
    • Identification and characterization of CMP-NeuAc:GalNAc-IgA1 a2,6-sialyltransferase in IgA1-producing cells
    • Raska M, Moldoveanu Z, Suzuki H et al. Identification and characterization of CMP-NeuAc:GalNAc-IgA1 a2,6-sialyltransferase in IgA1-producing cells. J Mol Biol 2007; 369: 69-78.
    • (2007) J Mol Biol , vol.369 , pp. 69-78
    • Raska, M.1    Moldoveanu, Z.2    Suzuki, H.3
  • 58
    • 0035991411 scopus 로고    scopus 로고
    • Interactions of human mesangial cells with IgA and IgA-containing immune complexes
    • Novak J, Vu HL, Novak L et al. Interactions of human mesangial cells with IgA and IgA-containing immune complexes. Kidney Int 2002; 62: 465-475.
    • (2002) Kidney Int , vol.62 , pp. 465-475
    • Novak, J.1    Vu, H.L.2    Novak, L.3
  • 59
    • 34249099962 scopus 로고    scopus 로고
    • IgA nephropathy and Henoch- Schoenlein purpura nephritis: Aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells
    • Novak J, Moldoveanu Z, Renfrow MB et al. IgA nephropathy and Henoch- Schoenlein purpura nephritis: aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells. Contrib Nephrol 2007; 157: 134-138.
    • (2007) Contrib Nephrol , vol.157 , pp. 134-138
    • Novak, J.1    Moldoveanu, Z.2    Renfrow, M.B.3
  • 60
    • 21444448470 scopus 로고    scopus 로고
    • Determination of aberrant O-glycosylation in the IgA1 hinge region by electron capture dissociation fourier transform-ion cyclotron resonance mass spectrometry
    • Renfrow MB, Cooper HJ, Tomana M et al. Determination of aberrant O-glycosylation in the IgA1 hinge region by electron capture dissociation fourier transform-ion cyclotron resonance mass spectrometry. J Biol Chem 2005; 280: 19136-19145.
    • (2005) J Biol Chem , vol.280 , pp. 19136-19145
    • Renfrow, M.B.1    Cooper, H.J.2    Tomana, M.3
  • 61
    • 35648929345 scopus 로고    scopus 로고
    • Analysis of O-glycan heterogeneity in IgA1 myeloma proteins by Fourier transform ion cyclotron resonance mass spectrometry: Implications for IgA nephropathy
    • Renfrow MB, Mackay CL, Chalmers MJ et al. Analysis of O-glycan heterogeneity in IgA1 myeloma proteins by Fourier transform ion cyclotron resonance mass spectrometry: implications for IgA nephropathy. Anal Bioanal Chem 2007; 389: 1397-1407.
    • (2007) Anal Bioanal Chem , vol.389 , pp. 1397-1407
    • Renfrow, M.B.1    MacKay, C.L.2    Chalmers, M.J.3
  • 62
    • 77954692713 scopus 로고    scopus 로고
    • Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: A comparative binding study
    • Gomes MM, Suzuki H, Brooks MT et al. Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study. Biochemistry 2010; 49: 5671-5682.
    • (2010) Biochemistry , vol.49 , pp. 5671-5682
    • Gomes, M.M.1    Suzuki, H.2    Brooks, M.T.3
  • 63
    • 80155171873 scopus 로고    scopus 로고
    • IgA1 immune complexes from pediatric pat ients with IgA nephropathy activate cultured human mesangial cells
    • .Novak J, Raskova Kafkova L, Suzuki H et al. IgA1 immune complexes from pediatric pat ients with IgA nephropathy activate cultured human mesangial cells. Nephrol Dial Transplant 2011; 26: 3451-3457.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 3451-3457
    • Novak, J.1    Raskova Kafkova, L.2    Suzuki, H.3
  • 64
    • 0032478524 scopus 로고    scopus 로고
    • Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
    • Lebron JA, Bennett MJ, Vaughn DE et al. Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell 1998; 93: 111-123.
    • (1998) Cell , vol.93 , pp. 111-123
    • Lebron, J.A.1    Bennett, M.J.2    Vaughn, D.E.3
  • 65
    • 82455210822 scopus 로고    scopus 로고
    • Both IgA nephropathy and alcoholic cirrhosis feature abnormally glycosylated IgA1 and soluble CD89-IgA and IgG-IgA complexes: Common mechanisms for distinct diseases
    • Tissandie E, Morelle W, Berthelot L et al. Both IgA nephropathy and alcoholic cirrhosis feature abnormally glycosylated IgA1 and soluble CD89-IgA and IgG-IgA complexes: common mechanisms for distinct diseases. Kidney Int 2011; 80: 1352-1363.
    • (2011) Kidney Int , vol.80 , pp. 1352-1363
    • Tissandie, E.1    Morelle, W.2    Berthelot, L.3
  • 66
    • 70349618909 scopus 로고    scopus 로고
    • Glomerular disease: The Oxford classification-predicting progression of IgAN
    • Eitner F, Floege J. Glomerular disease: the Oxford classification- predicting progression of IgAN. Nat Rev Nephrol 2009; 5: 557-559.
    • (2009) Nat Rev Nephrol , vol.5 , pp. 557-559
    • Eitner, F.1    Floege, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.