Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors

International Journal of Developmental Neuroscience

Volumn 31, Issue 1, 2013, Pages 36-45

  Hartlage Rübsamen, Maike ^a   Waniek, Alexander ^a   Roßner, Steffen ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

APP secretion; Glutamate receptors; Munc13; Organotypic brain slice culture; Phorbol ester; Synaptic activity

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GLUTAMATE RECEPTOR; MEMBRANE PROTEIN; POTASSIUM ION; PROTEIN MUNC13 1; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL ACTIVITY; CONTROLLED STUDY; GENE INACTIVATION; GENOTYPE; INTRACELLULAR SIGNALING; MOUSE; MUNC13 GENE; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PHARMACOLOGICAL STIMULATION; POSTSYNAPTIC MEMBRANE; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN SECRETION; RECEPTOR BLOCKING;

AMYLOID BETA-PROTEIN PRECURSOR; ANESTHETICS, LOCAL; ANIMALS; BRAIN; CALCIUM CHANNEL BLOCKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; GENOTYPE; GLUTAMIC ACID; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KYNURENIC ACID; L-LACTATE DEHYDROGENASE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NERVE TISSUE PROTEINS; NEURONS; ORGAN CULTURE TECHNIQUES; PHORBOL ESTERS; POTASSIUM CHLORIDE; RECEPTORS, GLUTAMATE; SYNAPSES; TETANUS TOXIN; TETRODOTOXIN; TIME FACTORS;

MUS;

EID: 84870561902     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2012.10.001     Document Type: Article

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