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Volumn 132, Issue 12, 2012, Pages 2818-2827

GSK3β Inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; FOCAL ADHESION KINASE 1; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; NP 309; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SLUG; UNCLASSIFIED DRUG;

EID: 84870515328     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.237     Document Type: Article
Times cited : (36)

References (42)
  • 1
    • 77950847051 scopus 로고    scopus 로고
    • FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells
    • Abel EV, Aplin AE (2010) FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells. Cancer Res 70:2891-900
    • (2010) Cancer Res , vol.70 , pp. 2891-2900
    • Abel, E.V.1    Aplin, A.E.2
  • 2
    • 80755138384 scopus 로고    scopus 로고
    • In melanoma, beta-catenin is a suppressor of invasion
    • Arozarena I, Bischof H, Gilby D et al. (2011) In melanoma, beta-catenin is a suppressor of invasion. Oncogene 30:4531-43
    • (2011) Oncogene , vol.30 , pp. 4531-4543
    • Arozarena, I.1    Bischof, H.2    Gilby, D.3
  • 3
    • 59649119743 scopus 로고    scopus 로고
    • Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3
    • Atilla-Gokcumen GE, Pagano N, Streu C et al. (2008) Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem 9:2933-6
    • (2008) Chembiochem , vol.9 , pp. 2933-2936
    • Atilla-Gokcumen, G.E.1    Pagano, N.2    Streu, C.3
  • 4
    • 79952781372 scopus 로고    scopus 로고
    • A prospective multicenter phase II trial of systemic ADH-1 in combination with melphalan via isolated limb infusion (M-ILI) in patients with advanced extremity melanoma
    • Beasley G, Sanders G, Zager JS et al. (2011) A prospective multicenter phase II trial of systemic ADH-1 in combination with melphalan via isolated limb infusion (M-ILI) in patients with advanced extremity melanoma. J Clin Oncol 29:1210-5
    • (2011) J Clin Oncol , vol.29 , pp. 1210-1215
    • Beasley, G.1    Sanders, G.2    Zager, J.S.3
  • 6
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • DOI 10.1038/nature03096
    • Bhowmick NA, Neilson EG, Moses HL (2004b) Stromal fibroblasts in cancer initiation and progression. Nature 432:332-7 (Pubitemid 39551661)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 7
    • 77954214841 scopus 로고    scopus 로고
    • Striking the target in Wnt-y conditions: Intervening in Wnt signaling during cancer progression
    • Camilli TC, Weeraratna AT (2010) Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progression. Biochem Pharmacol 80:702-11
    • (2010) Biochem Pharmacol , vol.80 , pp. 702-711
    • Camilli, T.C.1    Weeraratna, A.T.2
  • 8
    • 59049101982 scopus 로고    scopus 로고
    • Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
    • Chien AJ, Moore EC, Lonsdorf AS et al. (2009) Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc Natl Acad Sci USA 106:1193-8
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1193-1198
    • Chien, A.J.1    Moore, E.C.2    Lonsdorf, A.S.3
  • 10
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross DA, Alessi DR, Cohen P et al. (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-9 (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 11
    • 53849132331 scopus 로고    scopus 로고
    • A novel AKT3 mutation in melanoma tumours and cell lines
    • Davies MA, Stemke-Hale K, Tellez C et al. (2008) A novel AKT3 mutation in melanoma tumours and cell lines. Br J Cancer 99:1265-8
    • (2008) Br J Cancer , vol.99 , pp. 1265-1268
    • Davies, M.A.1    Stemke-Hale, K.2    Tellez, C.3
  • 12
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization
    • Diehl JA, Cheng M, Roussel MF et al. (1998) Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 12:3499-511 (Pubitemid 28553242)
    • (1998) Genes and Development , vol.12 , Issue.22 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 13
    • 0037092042 scopus 로고    scopus 로고
    • An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling
    • DOI 10.1083/jcb.200201098
    • Eickholt BJ, Walsh FS, Doherty P (2002) An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. J Cell Biol 157:211-7 (Pubitemid 34839818)
    • (2002) Journal of Cell Biology , vol.157 , Issue.2 , pp. 211-217
    • Eickholt, B.J.1    Walsh, F.S.2    Doherty, P.3
  • 14
    • 82955172970 scopus 로고    scopus 로고
    • Fibroblasts contribute to melanoma tumor growth and drug resistance
    • Flach E, Rebecca VW, Herlyn M et al. (2011) Fibroblasts contribute to melanoma tumor growth and drug resistance. Mol Pharm 8:2039-49
    • (2011) Mol Pharm , vol.8 , pp. 2039-2049
    • Flach, E.1    Rebecca, V.W.2    Herlyn, M.3
  • 15
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • DOI 10.1042/0264-6021:3590001
    • Frame S, Cohen P (2001) GSK3 takes centre stage more than 20 years after its discovery. Biochem J 359:1-16 (Pubitemid 32939202)
    • (2001) Biochemical Journal , vol.359 , Issue.1 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 16
    • 36749013537 scopus 로고    scopus 로고
    • Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
    • DOI 10.1038/ncb1658, PII NCB1658
    • Gaggioli C, Hooper S, Hidalgo-Carcedo C et al. (2007) Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 9:1392-400 (Pubitemid 350201752)
    • (2007) Nature Cell Biology , vol.9 , Issue.12 , pp. 1392-1400
    • Gaggioli, C.1    Hooper, S.2    Hidalgo-Carcedo, C.3    Grosse, R.4    Marshall, J.F.5    Harrington, K.6    Sahai, E.7
  • 17
    • 33750469653 scopus 로고    scopus 로고
    • Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3β) independently of Akt/PKB serine phosphorylation
    • DOI 10.1242/jcs.03159
    • Gartner A, Huang X, Hall A (2006) Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3beta) independently of Akt/PKB serine phosphorylation. J Cell Sci 119:3927-34 (Pubitemid 44650866)
    • (2006) Journal of Cell Science , vol.119 , Issue.19 , pp. 3927-3934
    • Gartner, A.1    Huang, X.2    Hall, A.3
  • 19
    • 19544362066 scopus 로고    scopus 로고
    • Adhesion, migration and communication in melanocytes and melanoma
    • DOI 10.1111/j.1600-0749.2005.00235.x
    • Haass NK, Smalley KS, Li L et al. (2005) Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Res 18: 150-9 (Pubitemid 40733333)
    • (2005) Pigment Cell Research , vol.18 , Issue.3 , pp. 150-159
    • Haass, N.K.1    Smalley, K.S.M.2    Li, L.3    Herlyn, M.4
  • 20
    • 77953878405 scopus 로고    scopus 로고
    • Adherens junctions: From molecules to morphogenesis
    • Harris TJ, Tepass U (2010) Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol 11:502-14
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 502-514
    • Harris, T.J.1    Tepass, U.2
  • 22
    • 0034025433 scopus 로고    scopus 로고
    • Cadherin repertoire determines partner-specific gap junctional communication during melanoma progression
    • Hsu MY, Andl T, Li G et al. (2000a) Cadherin repertoire determines partnerspecific gap junctional communication during melanoma progression. J Cell Sci 113:1535-42 (Pubitemid 30312502)
    • (2000) Journal of Cell Science , vol.113 , Issue.9 , pp. 1535-1542
    • Hsu, M.-Y.1    Andl, T.2    Li, G.3    Meinkoth, J.L.4    Herlyn, M.5
  • 23
    • 0033838767 scopus 로고    scopus 로고
    • E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors
    • Hsu MY, Meier FE, Nesbit M et al. (2000b) E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am J Pathol 156:1515-25 (Pubitemid 30646691)
    • (2000) American Journal of Pathology , vol.156 , Issue.5 , pp. 1515-1525
    • Hsu, M.-Y.1    Meier, F.E.2    Nesbit, M.3    Hsu, J.-Y.4    Van Belle, P.5    Elder, D.E.6    Herlyn, M.7
  • 24
    • 0029120440 scopus 로고
    • Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
    • Ilic D, Furuta Y, Kanazawa S et al. (1995) Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377:539-44
    • (1995) Nature , vol.377 , pp. 539-544
    • Ilic, D.1    Furuta, Y.2    Kanazawa, S.3
  • 25
    • 33845660854 scopus 로고    scopus 로고
    • FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration
    • DOI 10.1002/jcp.20870
    • Jacamo R, Jiang X, Lunn JA et al. (2007) FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration. J Cell Physiol 210:436-44 (Pubitemid 44956889)
    • (2007) Journal of Cellular Physiology , vol.210 , Issue.2 , pp. 436-444
    • Jacamo, R.1    Jiang, X.2    Lunn, J.A.3    Rozengurt, E.4
  • 28
    • 0035328628 scopus 로고    scopus 로고
    • N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells
    • Li G, Satyamoorthy K, Herlyn M (2001) N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells. Cancer Res 61:3819-25 (Pubitemid 32694999)
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3819-3825
    • Li, G.1    Satyamoorthy, K.2    Herlyn, M.3
  • 29
    • 0038456148 scopus 로고    scopus 로고
    • Function and regulation of melanoma-stromal fibroblast interactions: When seeds meet soil
    • DOI 10.1038/sj.onc.1206455, Melanoma
    • Li G, Satyamoorthy K, Meier F et al. (2003) Function and regulation of melanoma-stromal fibroblast interactions: when seeds meet soil. Oncogene 22:3162-71 (Pubitemid 36713768)
    • (2003) Oncogene , vol.22 , Issue.20 , pp. 3162-3171
    • Li, G.1    Satyamoorthy, K.2    Meier, F.3    Berking, C.4    Bogenrieder, T.5    Herlyn, M.6
  • 30
    • 33947547489 scopus 로고    scopus 로고
    • Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells
    • DOI 10.2353/ajpath.2007.060343
    • Lioni M, Brafford P, Andl C et al. (2007) Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells. Am J Pathol 170:709-21 (Pubitemid 47342407)
    • (2007) American Journal of Pathology , vol.170 , Issue.2 , pp. 709-721
    • Lioni, M.1    Brafford, P.2    Andl, C.3    Rustgi, A.4    El-Deiry, W.5    Herlyn, M.6    Smalley, K.S.M.7
  • 32
    • 77953276524 scopus 로고    scopus 로고
    • Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy
    • Paraiso KH, Fedorenko IV, Cantini LP et al. (2010) Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy. Br J Cancer 102:1724-30
    • (2010) Br J Cancer , vol.102 , pp. 1724-1730
    • Paraiso, K.H.1    Fedorenko, I.V.2    Cantini, L.P.3
  • 33
    • 79953325104 scopus 로고    scopus 로고
    • PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression
    • Paraiso KH, Xiang Y, Rebecca VW et al. (2011) PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression. Cancer Res 71:2750-60
    • (2011) Cancer Res , vol.71 , pp. 2750-2760
    • Paraiso, K.H.1    Xiang, Y.2    Rebecca, V.W.3
  • 34
    • 24344467835 scopus 로고    scopus 로고
    • Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the β-catenin signaling pathway
    • DOI 10.1091/mbc.E05-03-0186
    • Qi J, Chen N, Wang J et al. (2005) Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the betacatenin signaling pathway. Mol Biol Cell 16:4386-97 (Pubitemid 41262905)
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.9 , pp. 4386-4397
    • Qi, J.1    Chen, N.2    Wang, J.3    Siu, C.-H.4
  • 35
    • 84861615174 scopus 로고    scopus 로고
    • Slug expression during melanoma progression
    • Shirley SH, Greene VR, Duncan LM et al. (2012) Slug expression during melanoma progression. Am J Pathol 180:2479-89
    • (2012) Am J Pathol , vol.180 , pp. 2479-2489
    • Shirley, S.H.1    Greene, V.R.2    Duncan, L.M.3
  • 36
    • 17844406903 scopus 로고    scopus 로고
    • Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion
    • Smalley KS, Brafford P, Haass NK et al. (2005) Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion. Am J Pathol 166:1541-54 (Pubitemid 40586522)
    • (2005) American Journal of Pathology , vol.166 , Issue.5 , pp. 1541-1554
    • Smalley, K.S.M.1    Brafford, P.2    Haass, N.K.3    Brandner, J.M.4    Brown, E.5    Herlyn, M.6
  • 38
    • 33745075558 scopus 로고    scopus 로고
    • Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases
    • DOI 10.1158/1535-7163.MCT-06-0084
    • Smalley KS, Haass NK, Brafford PA et al. (2006) Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Mol Cancer Ther 5:1136-44 (Pubitemid 43881305)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.5 , pp. 1136-1144
    • Smalley, K.S.M.1    Haass, N.K.2    Brafford, P.A.3    Lioni, M.4    Flaherty, K.T.5    Herlyn, M.6
  • 40
    • 1442274619 scopus 로고    scopus 로고
    • Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma
    • DOI 10.1046/j.0022-202X.2004.22243.x
    • Tsao H, Goel V, Wu H et al. (2004) Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma. J Invest Dermatol 122:337-41 (Pubitemid 38281053)
    • (2004) Journal of Investigative Dermatology , vol.122 , Issue.2 , pp. 337-341
    • Tsao, H.1    Goel, V.2    Wu, H.3    Yang, G.4    Haluska, F.G.5
  • 41
    • 79551675515 scopus 로고    scopus 로고
    • Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3beta
    • Wu X, Shen QT, Oristian DS et al. (2011) Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3beta. Cell 144:341-52
    • (2011) Cell , vol.144 , pp. 341-352
    • Wu, X.1    Shen, Q.T.2    Oristian, D.S.3
  • 42
    • 0029683606 scopus 로고    scopus 로고
    • The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
    • Yost C, Torres M, Miller JR et al. (1996) The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev 10:1443-54 (Pubitemid 26260702)
    • (1996) Genes and Development , vol.10 , Issue.12 , pp. 1443-1454
    • Yost, C.1    Torres, M.2    Miller, J.R.3    Huang, E.4    Kimelman, D.5    Moon, R.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.