Whole-genome microRNA screening identifies let-7 and miR-18 as regulators of germ layer formation during early embryogenesis

Genes and Development

Volumn 26, Issue 23, 2012, Pages 2567-2579

  Colas, Alexandre R ^a   Mckeithan, Wesley L ^a   Cunningham, Thomas J ^a   Bushway, Paul J ^a   Garmire, Lana X ^b   Duester, Gregg ^a   Subramaniam, Shankar ^b   Mercola, Mark ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Embryonic stem cells; Endoderm; Germ layer; High throughput screening; Let 7; MicroRNA; Mir 18

Indexed keywords

GROWTH FACTOR; MICRORNA; MICRORNA LET7; MICRORNA MIR18; NODAL SIGNALING PROTEIN; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE ACVR1B; SMAD2 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLASTOCYTE; CELL FATE; CONTROLLED STUDY; DOWN REGULATION; ECTODERM; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENDODERM; GENETIC IDENTIFICATION; GENETIC SCREENING; GERM LAYER; MESODERM; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; REGULATORY MECHANISM; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; DNA MUTATIONAL ANALYSIS; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GENOME; GERM LAYERS; MICE; MICRORNAS; XENOPUS LAEVIS;

AMPHIBIA; ANURA; MAMMALIA;

EID: 84870480977     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.200758.112     Document Type: Article

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