-
2
-
-
2442563304
-
Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
-
Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 2004;126:1504-17
-
(2004)
Gastroenterology
, vol.126
, pp. 1504-1517
-
-
Loftus Jr., E.V.1
-
3
-
-
9244261570
-
Inflammatory bowel disease and smoking: A review of epidemiology, pathophysiology, and therapeutic implications
-
Birrenbach T, Bocker U. Inflammatory bowel disease and smoking: a review of epidemiology, pathophysiology, and therapeutic implications. Inflamm Bowel Dis 2004;10:848-59
-
(2004)
Inflamm Bowel Dis
, vol.10
, pp. 848-859
-
-
Birrenbach, T.1
Bocker, U.2
-
4
-
-
0028216254
-
Appendectomy protects against ulcerative colitis
-
Rutgeerts P, D'Haens G, Hiele M, et al. Appendectomy protects against ulcerative colitis. Gastroenterology 1994;106:1251-3
-
(1994)
Gastroenterology
, vol.106
, pp. 1251-1253
-
-
Rutgeerts, P.1
D'Haens, G.2
Hiele, M.3
-
5
-
-
0036457057
-
Inflammatory bowel disease: New insights into pathogenesis and treatment
-
Ardizzone S, Bianchi Porro G. Inflammatory bowel disease: new insights into pathogenesis and treatment. J Intern Med 2002;252:475-96
-
(2002)
J Intern Med
, vol.252
, pp. 475-496
-
-
Ardizzone, S.1
Bianchi Porro, G.2
-
6
-
-
0033952947
-
The natural history of ulcerative proctitis: a multicenter, retrospective study. Gruppo di Studio per le Malattie Infiammatorie Intestinali (GSMII)
-
Meucci G, Vecchi M, Astegiano M, et al. The natural history of ulcerative proctitis: a multicenter, retrospective study. Gruppo di Studio per le Malattie Infiammatorie Intestinali (GSMII). Am J Gastroenterol 2000;95:469-73
-
(2000)
Am J Gastroenterol
, vol.95
, pp. 469-473
-
-
Meucci, G.1
Vecchi, M.2
Astegiano, M.3
-
7
-
-
33847179443
-
A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis
-
D'Haens G, Sandborn WJ, Feagan BG, et al. A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis. Gastroenterology 2007;132:763-86
-
(2007)
Gastroenterology
, vol.132
, pp. 763-786
-
-
D'Haens, G.1
Sandborn, W.J.2
Feagan, B.G.3
-
8
-
-
0008690916
-
Cortisone in ulcerative colitis: Final report on a therapeutic trial
-
Truelove SC, Witts LJ. Cortisone in ulcerative colitis: final report on a therapeutic trial. Br Med J 1955;ii:1041-8
-
(1955)
Br Med J
, vol.2
, pp. 1041-1048
-
-
Truelove, S.C.1
Witts, L.J.2
-
9
-
-
0023521441
-
Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study
-
Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med 1987;317:1625-9
-
(1987)
N Engl J Med
, vol.317
, pp. 1625-1629
-
-
Schroeder, K.W.1
Tremaine, W.J.2
Ilstrup, D.M.3
-
10
-
-
38749106156
-
European evidence-based Consensus on the diagnosis and management of ulcerative colitis: Definitions and diagnosis
-
Stange EF, Travis SPL, Vermeire S, et al. European evidence-based Consensus on the diagnosis and management of ulcerative colitis: definitions and diagnosis. J Crohn's Colitis 2008;2:1-23
-
(2008)
J Crohn's Colitis
, vol.2
, pp. 1-23
-
-
Stange, E.F.1
Spl, T.2
Vermeire, S.3
-
11
-
-
0028338424
-
Course of ulcerative colitis: Analyis of changes in disease activity over years
-
Langholz E, Munkholm P, Davidsen M, et al. Course of ulcerative colitis: analyis of changes in disease activity over years. Gastroenterology 1994;107:3-11
-
(1994)
Gastroenterology
, vol.107
, pp. 3-11
-
-
Langholz, E.1
Munkholm, P.2
Davidsen, M.3
-
12
-
-
67049137968
-
Clinical course during the firts 10 years of ulcerative colitis: Results from a population- based inception cohort (IBSEN study)
-
Solberg IC, Lygren I, Jahnsen J, et al. Clinical course during the firts 10 years of ulcerative colitis: results from a population- based inception cohort (IBSEN study). Scand J Gastroenterol 2009;44:431-40
-
(2009)
Scand J Gastroenterol
, vol.44
, pp. 431-440
-
-
Solberg, I.C.1
Lygren, I.2
Jahnsen, J.3
-
13
-
-
34548324538
-
Review article: The management of steroid-dependency in ulcerative colitis
-
Bianchi Porro G, Cassinotti A, Ferrara E, et al. Review article: the management of steroid-dependency in ulcerative colitis. Aliment Pharmacol Ther 2007;26:779-94
-
(2007)
Aliment Pharmacol Ther
, vol.26
, pp. 779-794
-
-
Bianchi Porro, G.1
Cassinotti, A.2
Ferrara, E.3
-
14
-
-
0029033690
-
Characteristic morphologic changes in chronic ulcerative colitis
-
Gore RM. Characteristic morphologic changes in chronic ulcerative colitis. Abdom Imaging 1995;20:275-7
-
(1995)
Abdom Imaging
, vol.20
, pp. 275-277
-
-
Gore, R.M.1
-
15
-
-
84857795955
-
Ulcerative colitis as a sole mucosal disease: Another misunderstanding?
-
Torres J, Billioud V, Peyrin-Biroulet L, et al. Ulcerative colitis as a sole mucosal disease: another misunderstanding? Gut 2012;61:633
-
(2012)
Gut
, vol.61
, pp. 633
-
-
Torres, J.1
Billioud, V.2
Peyrin-Biroulet, L.3
-
16
-
-
0035080617
-
The risk of colorectal cancer in ulcerative colitis: A meta-analysis
-
Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001;48:526-35
-
(2001)
Gut
, vol.48
, pp. 526-535
-
-
Eaden, J.A.1
Abrams, K.R.2
Mayberry, J.F.3
-
17
-
-
0038382993
-
The state of the art in the management of inflammatory bowel disease
-
Hanauer SB, Preent DH. The state of the art in the management of inflammatory bowel disease. Rev Gastroenterol Disord 2003;3:81-92
-
(2003)
Rev Gastroenterol Disord
, vol.3
, pp. 81-92
-
-
Hanauer, S.B.1
Preent, D.H.2
-
18
-
-
84858386221
-
Mesalamine in the treatment and maintenance of remission of ulcerative colitis
-
Ham M, Moss AC. Mesalamine in the treatment and maintenance of remission of ulcerative colitis. Expert Rv Clin Pharmacol 2012;5:113-23
-
(2012)
Expert Rv Clin Pharmacol
, vol.5
, pp. 113-123
-
-
Ham, M.1
Moss, A.C.2
-
19
-
-
79955557278
-
Conventional medical management of inflammatory bowel disease
-
e2
-
Burger D, Travis S. Conventional medical management of inflammatory bowel disease. Gastroenterology 2011;140:1827-37; e2
-
(2011)
Gastroenterology
, vol.140
, pp. 1827-1837
-
-
Burger, D.1
Travis, S.2
-
20
-
-
0034903792
-
The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study
-
Faubion WA Jr, Loftus EV Jr, Harmsen WS, et al. The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 2001;121:255-60
-
(2001)
Gastroenterology
, vol.121
, pp. 255-260
-
-
Faubion Jr., W.A.1
Loftus Jr., E.V.2
Harmsen, W.S.3
-
21
-
-
79957452795
-
Mucosal healing predicts late outcomes after the first course of corticosteroids for newly diagnosed ulcerative colitis
-
Ardizzone S, Cassinotti A, Duca P, et al. Mucosal healing predicts late outcomes after the first course of corticosteroids for newly diagnosed ulcerative colitis. Clin Gastroenterol Hepatol 2011;9:483-489.e3
-
(2011)
Clin Gastroenterol Hepatol
, vol.9
-
-
Ardizzone, S.1
Cassinotti, A.2
Duca, P.3
-
22
-
-
0036278519
-
The efficacy of azathioprine for the treatment of inflammatory bowel disease: A 30 year review
-
Fraser AG, Orchard TR, Jewell DP. The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 2002;50:485-9
-
(2002)
Gut
, vol.50
, pp. 485-489
-
-
Fraser, A.G.1
Orchard, T.R.2
Jewell, D.P.3
-
23
-
-
29244457275
-
Randomized controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis
-
Ardizzone S, Maconi G, Russo A, et al. Randomized controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut 2006;55:47-53
-
(2006)
Gut
, vol.55
, pp. 47-53
-
-
Ardizzone, S.1
MacOni, G.2
Russo, A.3
-
24
-
-
39149120115
-
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
-
Timmer A, McDonald JW, McDonald JK. Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev 2007;1:CD000478
-
(2007)
Cochrane Database Syst Rev
, vol.1
-
-
Timmer, A.1
McDonald, J.W.2
McDonald, J.K.3
-
25
-
-
67649867062
-
Meta-analysis: The efficacy of azathioprine and mercaptopurine in ulcerative colitis
-
Gisbert JP, Linares PM, Mcnicholl AG, et al. Meta-analysis: the efficacy of azathioprine and mercaptopurine in ulcerative colitis. Aliment Pharmacol Ther 2009;30:126-37
-
(2009)
Aliment Pharmacol Ther
, vol.30
, pp. 126-137
-
-
Gisbert, J.P.1
Linares, P.M.2
McNicholl, A.G.3
-
26
-
-
79953778809
-
Efficacy of immunosuppressive therapy for inflammatory bowel disease: A systematic review and meta-analysis
-
Khan KJ, Dubinsk MC, Ford AC, et al. Efficacy of immunosuppressive therapy for inflammatory bowel disease: a systematic review and meta-analysis. Am J Gastroenterol 2011;106:630-42
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 630-642
-
-
Khan, K.J.1
Dubinsk, M.C.2
Ford, A.C.3
-
27
-
-
70449100743
-
Lymphoproliferative disorders in pateints receiving thiopurines for inflammatory bowel: A prospective observational cohort study
-
Beaugerie L, Brousse N, Bouvier AM, et al. Lymphoproliferative disorders in pateints receiving thiopurines for inflammatory bowel: a prospective observational cohort study. Lancet 2009;374:1617-25
-
(2009)
Lancet
, vol.374
, pp. 1617-1625
-
-
Beaugerie, L.1
Brousse, N.2
Bouvier, A.M.3
-
28
-
-
0015713214
-
The metabolic fate of the methylnitroimidazole moiety of azathioprine in the rat
-
De Miranda P, Beacham LM, Creagh TH, et al. The metabolic fate of the methylnitroimidazole moiety of azathioprine in the rat. J Pharmacol Exp Ther 1973;187:588-601
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 588-601
-
-
De Miranda, P.1
Beacham, L.M.2
Creagh, T.H.3
-
29
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 1992;43:329-39
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
30
-
-
0018822866
-
Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase acitivty
-
Weinshilboum RN, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase acitivty. Am J Hum Genet 1980;32:651-62
-
(1980)
Am J Hum Genet
, vol.32
, pp. 651-662
-
-
Weinshilboum, R.N.1
Sladek, S.L.2
-
31
-
-
0034067784
-
Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
-
Dubinsky MC, Lamothe S, Ying Yang H, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000;118:705-13
-
(2000)
Gastroenterology
, vol.118
, pp. 705-713
-
-
Dubinsky, M.C.1
Lamothe, S.2
Ying Yang, H.3
-
32
-
-
0024451147
-
Pharmacogenetics of acuteazathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism
-
Lennard L, Van Loon JA, Weinshilboum RM. Pharmacogenetics of acuteazathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism. Clin Pharmacol Ther 1989;46:149-54
-
(1989)
Clin Pharmacol Ther
, vol.46
, pp. 149-154
-
-
Lennard, L.1
Van Loon, J.A.2
Weinshilboum, R.M.3
-
33
-
-
0009938860
-
Azathioprine6- mercaptopurine: Mechanism of action pharmacology and toxicity
-
Fellerman K Jewell DP Sandborn WJ Schlmerich J Stange EF Editors, Kluwer Academic Publishers Dordrecht (NL)
-
Sandborn WJ. Azathioprine/6- mercaptopurine: mechanism of action, pharmacology and toxicity. In: Fellerman K, Jewell DP, Sandborn WJ, Schlmerich J, Stange EF, editors. Immunosuppression in inflammatory bowel diseases. Standards, new developments, future trends. Falk Symposium 119. Kluwer Academic Publishers; Dordrecht (NL): 2001. p. 91-100
-
(2001)
Immunosuppression in Inflammatory Bowel Diseases. Standards New Developments Future Trends. Falk Symposium
, vol.119
, pp. 91-100
-
-
Sandborn, W.J.1
-
34
-
-
79959652551
-
Assessment of thiopurine S-methyltransferase activity in patients prescribed thiopurines: A systematic review
-
Booth RA, Ansari MT, Loit E, et al. Assessment of thiopurine S-methyltransferase activity in patients prescribed thiopurines: a systematic review. Ann Intern Med 2011;154:814-23
-
(2011)
Ann Intern Med
, vol.154
, pp. 814-823
-
-
Booth, R.A.1
Ansari, M.T.2
Loit, E.3
-
35
-
-
80052902189
-
Use of thiopurine testing in the management of inflammatory bowel diseases in clinical practice: A worldwide survey of experts
-
Roblin X, Oussalah A, Chevaux JB, et al. Use of thiopurine testing in the management of inflammatory bowel diseases in clinical practice: a worldwide survey of experts. Inflamm Bowel Dis 2011;17:2480-7
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 2480-2487
-
-
Roblin, X.1
Oussalah, A.2
Chevaux, J.B.3
-
36
-
-
42449087386
-
Use of allopurinol with low-dose 6- mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: A review of four cases and the literature
-
Witte TN, Ginsberg AL. Use of allopurinol with low-dose 6- mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: a review of four cases and the literature. Can J Gastroenterol 2008;22:181-5
-
(2008)
Can J Gastroenterol
, vol.22
, pp. 181-185
-
-
Witte, T.N.1
Ginsberg, A.L.2
-
37
-
-
77957301876
-
Combination of thiopurines and allopurinol: Adverse events and clinical benefit in IBD
-
Govani SM, Higgins PDR. Combination of thiopurines and allopurinol: adverse events and clinical benefit in IBD. J Crohns Colitis 2010;4:444-9
-
(2010)
J Crohns Colitis
, vol.4
, pp. 444-449
-
-
Govani, S.M.1
Higgins, P.D.R.2
-
38
-
-
84865713570
-
Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol
-
Smith MA, Blaker P, Marinaki AM, et al. Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol. J Crohns Colitis 2012;6:905-12
-
(2012)
J Crohns Colitis
, vol.6
, pp. 905-912
-
-
Smith, M.A.1
Blaker, P.2
Marinaki, A.M.3
-
40
-
-
9244264980
-
Methotrexate in chronic active ulcerative colitis: A double-blind, randomized, Israeli multicenter trial
-
Oren R, Arber N, Odes S, et al. Methotrexate in chronic active ulcerative colitis: a double-blind, randomized, Israeli multicenter trial. Gastroenterology 1996;110:1416-21
-
(1996)
Gastroenterology
, vol.110
, pp. 1416-1421
-
-
Oren, R.1
Arber, N.2
Odes, S.3
-
42
-
-
10744231879
-
Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclosporine in severe ulcerative colitis
-
Van Assche G, D'Haens G, Noman M, et al. Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclosporine in severe ulcerative colitis. Gastroenterology 2003;125:1025-31
-
(2003)
Gastroenterology
, vol.125
, pp. 1025-1031
-
-
Van Assche, G.1
D'Haens, G.2
Noman, M.3
-
43
-
-
1542619846
-
Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis
-
Arts J, D'Haens G, Zeegers M. Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis. Inflamm Bowel Dis 2004;1:73-8
-
(2004)
Inflamm Bowel Dis
, vol.1
, pp. 73-78
-
-
Arts, J.1
D'Haens, G.2
Zeegers, M.3
-
44
-
-
33747790601
-
A randomized dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis
-
Ogata H, Matsui T, Nakamura M, et al. A randomized dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis. Gut 2006;55:1255-62
-
(2006)
Gut
, vol.55
, pp. 1255-1262
-
-
Ogata, H.1
Matsui, T.2
Nakamura, M.3
-
45
-
-
28844473957
-
Infliximab for induction and maintenance therapy for ulcerative colitis
-
Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005;353:2462-76
-
(2005)
N Engl J Med
, vol.353
, pp. 2462-2476
-
-
Rutgeerts, P.1
Sandborn, W.J.2
Feagan, B.G.3
-
46
-
-
70349418632
-
Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab
-
Sandborn WJ, Rutgeerts P, Feagan BG, et al. Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab. Gastroenterology 2009;137:1250-60
-
(2009)
Gastroenterology
, vol.137
, pp. 1250-1260
-
-
Sandborn, W.J.1
Rutgeerts, P.2
Feagan, B.G.3
-
47
-
-
80053130407
-
Early mucosal healing with infliximab is associated with improved long- term clinical outcomes in ulcerative colitis
-
Colombel JF, Rutgeerts P, Reinisch W, et al. Early mucosal healing with infliximab is associated with improved long- term clinical outcomes in ulcerative colitis. Gastroenterology 2011;141:1194-201
-
(2011)
Gastroenterology
, vol.141
, pp. 1194-1201
-
-
Colombel, J.F.1
Rutgeerts, P.2
Reinisch, W.3
-
48
-
-
80455139421
-
-
DDW; 7 - 10 May; Chicago, IL, USA
-
Panaccione R, Ghosh S, Middleton S, et al. Infliximab, Azathioprine, or Infliximab + azathioprine for treatment of moderate to severe ulcerative colitis: the UC success trial. DDW; 7 - 10 May, 2011; Chicago, IL, USA
-
(2011)
Infliximab, Azathioprine, or Infliximab + Azathioprine for Treatment of Moderate to Severe Ulcerative Colitis: The UC Success Trial
-
-
Panaccione, R.1
Ghosh, S.2
Middleton, S.3
-
49
-
-
20444479336
-
Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: A randomized, placebo-controlled study
-
Jarnerot G, Hertervig E, Friis-Liby I, et al. Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study. Gastroenterology 2005;128:1805-11
-
(2005)
Gastroenterology
, vol.128
, pp. 1805-1811
-
-
Jarnerot, G.1
Hertervig, E.2
Friis-Liby, I.3
-
50
-
-
80755165415
-
Cyclosporin versus infliximab in severe acute ulcerative colitis refractory to intravenous steroids: A randomized trial
-
61084-61088
-
Laharie D, Bourreille A, Branche J, et al. Cyclosporin versus Infliximab in severe acute ulcerative colitis refractory to intravenous steroids: a randomized trial. Lancet 2012;pii; S0140-6736 (12)61084-8
-
(2012)
Lancet
, Issue.12
-
-
Laharie, D.1
Bourreille, A.2
Branche, J.3
-
51
-
-
52949131525
-
Cyclosporine and infliximab as rescue therapy for each other in patients with steroid-refractory ulcerative colitis
-
Maser EA, Deconda D, Lichtiger S, et al. Cyclosporine and infliximab as rescue therapy for each other in patients with steroid-refractory ulcerative colitis. Clin Gastroenterol Hepatol 2008;6:1112-16
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 1112-1116
-
-
Maser, E.A.1
Deconda, D.2
Lichtiger, S.3
-
52
-
-
79955859430
-
Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: Results of a randomized controlled trial
-
Reinisch W, Sandborn WJ, Hommes DW, et al. Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomized controlled trial. Gut 2011;60:780-7
-
(2011)
Gut
, vol.60
, pp. 780-787
-
-
Reinisch, W.1
Sandborn, W.J.2
Hommes, D.W.3
-
53
-
-
84856163835
-
Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis
-
Sandborn WJ, Van Assche G, Reinisch W, et al. Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology 2012;42:257-65
-
(2012)
Gastroenterology
, vol.42
, pp. 257-265
-
-
Sandborn, W.J.1
Van Assche, G.2
Reinisch, W.3
-
55
-
-
33750105599
-
Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis
-
Lawson MM, Thomas AG, Akobeng AK. Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2006(3):CD005112
-
(2006)
Cochrane Database Syst Rev
, Issue.3
-
-
Lawson, M.M.1
Thomas, A.G.2
Akobeng, A.K.3
-
56
-
-
79960951518
-
A meta-analysis of the therapeutic effects of tumor necrosis factor - A blockers on ulcerative colitis
-
Huang X, Lv B, Jin HF, Zhang S. A meta-analysis of the therapeutic effects of tumor necrosis factor-a blockers on ulcerative colitis. Eur J Clin Pharmacol 2011;67:759-66
-
(2011)
Eur J Clin Pharmacol
, vol.67
, pp. 759-766
-
-
Huang, X.1
Lv, B.2
Jin, H.F.3
Zhang, S.4
-
57
-
-
79953801792
-
Efficacy of biological therapies in inflammatory bowel disease: Systematic review and meta-analysis
-
Ford AC, Sandborn WJ, Khan KJ, et al. Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol 2011;106:644-59
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 644-659
-
-
Ford, A.C.1
Sandborn, W.J.2
Khan, K.J.3
-
58
-
-
77649231105
-
Systematic review: The costs of ulcerative colitis in Western countries
-
Cohen R, Yu A, Wu E, et al. Systematic review: the costs of ulcerative colitis in Western countries. Aliment Pharmacol Ther 2010;31:693-707
-
(2010)
Aliment Pharmacol Ther
, vol.31
, pp. 693-707
-
-
Cohen, R.1
Yu, A.2
Wu, E.3
-
59
-
-
8744316830
-
Current concept of pathophysiological understanding and natural course of ulcerative colitis
-
Holtmann MH, Galle PR. Current concept of pathophysiological understanding and natural course of ulcerative colitis. Langenbecks Arch Surg 2004;389:341-9
-
(2004)
Langenbecks Arch Surg
, vol.389
, pp. 341-349
-
-
Holtmann, M.H.1
Galle, P.R.2
-
60
-
-
63449133697
-
How expensive is inflammatory bowel disease? A critical analysis
-
Odes S. How expensive is inflammatory bowel disease? A critical analysis. World J Gastroenterol 2008;14(43):6641-7
-
(2008)
World J Gastroenterol
, vol.14
, Issue.43
, pp. 6641-6647
-
-
Odes, S.1
-
61
-
-
0030730033
-
Inflammatory bowel diseases: Health care and costs in Sweden in 1994
-
Blomqvist P, Ekbom A. Inflammatory bowel diseases: health care and costs in Sweden in 1994. Scand J Gastroenterol 1997;32:1134-9
-
(1997)
Scand J Gastroenterol
, vol.32
, pp. 1134-1139
-
-
Blomqvist, P.1
Ekbom, A.2
-
62
-
-
33748120032
-
Cost analysis and cost determinants in a European inflammatory bowel disease inception cohort with 10 years of follow-up evaluation
-
Odes S, Vardi H, Friger M, et al. Cost analysis and cost determinants in a European inflammatory bowel disease inception cohort with 10 years of follow-up evaluation. Gastroenterology 2006;131:719-28
-
(2006)
Gastroenterology
, vol.131
, pp. 719-728
-
-
Odes, S.1
Vardi, H.2
Friger, M.3
-
63
-
-
79958801012
-
Managing the long term care of inflammatory bowel disease patients: The cost to European health care providers
-
Buchanan J, Wordsworth S, Ahmad T, et al. Managing the long term care of inflammatory bowel disease patients: the cost to European health care providers. JCC 2011;5:301-16
-
(2011)
JCC
, vol.5
, pp. 301-316
-
-
Buchanan, J.1
Wordsworth, S.2
Ahmad, T.3
-
64
-
-
58149094256
-
Systematic review: Impact of non-adherence to 5-aminosalicylic acid products on the frequency and cost of ulcerative colitis flares
-
Higgins P, Rubin D, Kaulback K, et al. Systematic review: impact of non-adherence to 5-aminosalicylic acid products on the frequency and cost of ulcerative colitis flares. Aliment Pharmacol Ther 2009;29:247-57
-
(2009)
Aliment Pharmacol Ther
, vol.29
, pp. 247-257
-
-
Higgins, P.1
Rubin, D.2
Kaulback, K.3
-
65
-
-
0026777406
-
Inflammatory bowel disease: Costs-of-illness
-
Hay JW, Hay AR. Inflammatory bowel disease: costs-of-illness. J Clin Gastroenterol 1992;14:309-17
-
(1992)
J Clin Gastroenterol
, vol.14
, pp. 309-317
-
-
Hay, J.W.1
Hay, A.R.2
-
66
-
-
54049088931
-
A model of the long-term costeffectiveness of scheduled maintenance treatment with infliximab for moderate to severe ulcerative colitis
-
Tsai HH, Punekar Y, Morris J, et al. A model of the long-term costeffectiveness of scheduled maintenance treatment with infliximab for moderate to severe ulcerative colitis. Aliment Pharmacol Ther 2008;28:1230-9
-
(2008)
Aliment Pharmacol Ther
, vol.28
, pp. 1230-1239
-
-
Tsai, H.H.1
Punekar, Y.2
Morris, J.3
-
67
-
-
73249153462
-
Cost-utility analysis of infliximab and adalimumab for refractory ulcerative colitis
-
Xie F, Blackhouse G, Assasi N, et al. Cost-utility analysis of infliximab and adalimumab for refractory ulcerative colitis. Cost Eff Resour Alloc 2009;7:20
-
(2009)
Cost Eff Resour Alloc
, vol.7
, pp. 20
-
-
Xie, F.1
Blackhouse, G.2
Assasi, N.3
-
68
-
-
0033770169
-
A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease
-
Markowitz J, Grancher K, Kohn N, et al. A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease. Gastroenterology 2000;119:895-902
-
(2000)
Gastroenterology
, vol.119
, pp. 895-902
-
-
Markowitz, J.1
Grancher, K.2
Kohn, N.3
-
69
-
-
39449085441
-
Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: An open randomised trial
-
D'Haens G, Baert F, van Assche G, et al. Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial. Lancet 2008;371:660-7
-
(2008)
Lancet
, vol.371
, pp. 660-667
-
-
D'Haens, G.1
Baert, F.2
Van Assche, G.3
-
70
-
-
66949174573
-
Safety of infliximab and other Crohn's disease therapies: TREAT registry data with 24575 patient-years of follow-up
-
Lichtenstein G, Cohen R, Feagan B, et al. Safety of infliximab and other Crohn's disease therapies: TREAT registry data with 24575 patient-years of follow-up. Am J Gastroenterol 2008;103:S436
-
(2008)
Am J Gastroenterol
, vol.103
-
-
Lichtenstein, G.1
Cohen, R.2
Feagan, B.3
-
71
-
-
41349088375
-
Risk factors for opportunistic infections in patients with inflammatory bowel disease
-
Toruner M, Loftus EV Jr, Harmsen WS, et al. Risk factors for opportunistic infections in patients with inflammatory bowel disease. Gastroenterology 2008;134:929-36
-
(2008)
Gastroenterology
, vol.134
, pp. 929-936
-
-
Toruner, M.1
Loftus Jr., E.V.2
Harmsen, W.S.3
-
72
-
-
72049097420
-
Maintenance treatment with azathioprine in ulcerative colitis: Outcome and predictive factors after drug withdrawal
-
Cassinotti A, Actis G, Duca P, et al. Maintenance treatment with azathioprine in ulcerative colitis: outcome and predictive factors after drug withdrawal. Am J Gastroenterol 2009;104:2760-7
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 2760-2767
-
-
Cassinotti, A.1
Actis, G.2
Duca, P.3
-
73
-
-
0028363515
-
Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease
-
Connell WR, Kamm MA, Dickson M, et al. Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease. Lancet 1994;343:1249-52
-
(1994)
Lancet
, vol.343
, pp. 1249-1252
-
-
Connell, W.R.1
Kamm, M.A.2
Dickson, M.3
-
74
-
-
22644446331
-
Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine
-
Kandiel A, Fraser AG, Korrelitz BI, et al. Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. Gut 2005;54:112-15
-
(2005)
Gut
, vol.54
, pp. 112-115
-
-
Kandiel, A.1
Fraser, A.G.2
Korrelitz, B.I.3
-
75
-
-
0034075584
-
Azathioprine for maintenance of remission in Crohn's disease: Benefits outweigh the risk of lymphoma
-
Lewis JD, Schwartz JS, Lichtenstein GR. Azathioprine for maintenance of remission in Crohn's disease: benefits outweigh the risk of lymphoma. Gastroenterology 2000;118:1018-24
-
(2000)
Gastroenterology
, vol.118
, pp. 1018-1024
-
-
Lewis, J.D.1
Schwartz, J.S.2
Lichtenstein, G.R.3
-
76
-
-
67949112671
-
Risk of lymphoma associated with combination antitumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: A meta-analysis
-
Siegel CA, Marden SM, Persing SM, et al. Risk of lymphoma associated with combination antitumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis. Clin Gastroenterol Hepatol 2009;7:874-81
-
(2009)
Clin Gastroenterol Hepatol
, vol.7
, pp. 874-881
-
-
Siegel, C.A.1
Marden, S.M.2
Persing, S.M.3
-
77
-
-
79751472562
-
The London position statement of the World Congress of Gastroenterology on biological therapy for IBD with the European Crohn's and Colitis Organization: When to start, when to stop, which drug to choose, and how to predict response?
-
D'Haens G, Panaccione R, Higgins P, et al. The London position statement of the World Congress of Gastroenterology on biological therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response? Am J Gastroenterol 2011;106:199-212
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 199-212
-
-
D'Haens, G.1
Panaccione, R.2
Higgins, P.3
-
78
-
-
84859043138
-
The future of inflammatory bowel disease management: Combining progress in trial design with advances in targeted therapy
-
Travis S, Feagan B, Rutgeerts P, et al. The future of inflammatory bowel disease management: combining progress in trial design with advances in targeted therapy. J Crohns Colitis 2012;6S2:S250-9
-
(2012)
J Crohns Colitis
, vol.6 S2
-
-
Travis, S.1
Feagan, B.2
Rutgeerts, P.3
-
79
-
-
84870411283
-
Risk of colorectal cancer in patients with ulcerative colitis: A meta-analysis of population-based cohort studies
-
Jess T, Rungoe C, Peyrin-Biroulet L. Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies. Clin Gastroenterol Hepatol 2011;9:483-9
-
(2011)
Clin Gastroenterol Hepatol
, vol.9
, pp. 483-489
-
-
Jess, T.1
Rungoe, C.2
Peyrin-Biroulet, L.3
-
80
-
-
21344446543
-
Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: A systematic review and metaanalysis of observational studies
-
Velayos FS, Terdiman JP, Walsh JM. Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. Am J Gastroenterol 2005;100:1345-53
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 1345-1353
-
-
Velayos, F.S.1
Terdiman, J.P.2
Walsh, J.M.3
-
81
-
-
84855206195
-
Thiopurines prevent advanced colorectal neoplasia in patients with inflammatory bowel disease
-
van Schaik FD, van Oijen MG, Smeets HM, et al. Thiopurines prevent advanced colorectal neoplasia in patients with inflammatory bowel disease. Gut 2012;61:235-40
-
(2012)
Gut
, vol.61
, pp. 235-240
-
-
Van Schaik, F.D.1
Van Oijen, M.G.2
Smeets, H.M.3
-
82
-
-
84860557456
-
New therapies for inflammatory bowel disease: From the bench to the bedside
-
Danese S. New therapies for inflammatory bowel disease: from the bench to the bedside. Gut 2012;61:918-32
-
(2012)
Gut
, vol.61
, pp. 918-932
-
-
Danese, S.1
-
83
-
-
85047690640
-
Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize and atypical Th2 response in ulcerative colitis
-
Fuss IJ, Heller F, Boirivant M, et al. Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize and atypical Th2 response in ulcerative colitis. J Clin Invest 2004;113:1490-7
-
(2004)
J Clin Invest
, vol.113
, pp. 1490-1497
-
-
Fuss, I.J.1
Heller, F.2
Boirivant, M.3
-
84
-
-
0036107919
-
Immunoregulation in the gut: Success and failures in human disease
-
Monteleone I, Vavassori P, Biancone L, et al. Immunoregulation in the gut: success and failures in human disease. Gut 2002;50:iii60-4
-
(2002)
Gut
, vol.50
-
-
Monteleone, I.1
Vavassori, P.2
Biancone, L.3
-
85
-
-
33644875407
-
Adhesion molecules in inflammatory bowel disease: Therapeutic implications for gut inflammation
-
Danese S, Semerraro S, Marini M, et al. Adhesion molecules in inflammatory bowel disease: therapeutic implications for gut inflammation. Dig Liver Dis 2005;37:811-18
-
(2005)
Dig Liver Dis
, vol.37
, pp. 811-818
-
-
Danese, S.1
Semerraro, S.2
Marini, M.3
-
86
-
-
0037428478
-
Structure and dynamics of thioguanine-modified duplex DNA
-
Somerville L, Krynetski EY, Krynetskaia NF, et al. Structure and dynamics of thioguanine-modified duplex DNA. J Biol Chem 2003;278:1005-11
-
(2003)
J Biol Chem
, vol.278
, pp. 1005-1011
-
-
Somerville, L.1
Krynetski, E.Y.2
Krynetskaia, N.F.3
-
87
-
-
0029822592
-
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine
-
Swann PF, Waters TR, Moulton DC, et al. Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science 1996;273:1109-11
-
(1996)
Science
, vol.273
, pp. 1109-1111
-
-
Swann, P.F.1
Waters, T.R.2
Moulton, D.C.3
-
88
-
-
0242464926
-
CD28-dependent Rac1 activa tion is the molecular target of azathioprine in primary human CD4+ T lymphocytes
-
Tiede I, Fritz G, Strand S, et al. CD28-dependent Rac1 activa tion is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J Clin Invest 2003;111:1133-45
-
(2003)
J Clin Invest
, vol.111
, pp. 1133-1145
-
-
Tiede, I.1
Fritz, G.2
Strand, S.3
-
89
-
-
29644444216
-
Azathioprine suppresses ezrin-radixinmoesin- dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins
-
Poppe D, Tiede I, Fritz G, et al. Azathioprine suppresses ezrin-radixinmoesin- dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins. J Immunol 2006;176(1):640-51
-
(2006)
J Immunol
, vol.176
, Issue.1
, pp. 640-651
-
-
Poppe, D.1
Tiede, I.2
Fritz, G.3
-
90
-
-
33646232018
-
Basiliximab for the treatment of steroid-resistant ulcerative colitis: Further experience in moderate and severe disease
-
Creed TJ, Probert CS, Norman MN, et al. Basiliximab for the treatment of steroid-resistant ulcerative colitis: further experience in moderate and severe disease. APT 2006;23:1435-42
-
(2006)
APT
, vol.23
, pp. 1435-1442
-
-
Creed, T.J.1
Probert, C.S.2
Norman, M.N.3
-
91
-
-
33750343050
-
Daclizumab, a humanized monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: A randomized, double-blind, placebo controlled, dose ranging trial
-
Van Assche G, Sandborn WJ, Feagan BG, et al. Daclizumab, a humanized monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomized, double-blind, placebo controlled, dose ranging trial. Gut 2006;55:1568-74
-
(2006)
Gut
, vol.55
, pp. 1568-1574
-
-
Van Assche, G.1
Sandborn, W.J.2
Feagan, B.G.3
-
92
-
-
23244455992
-
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution
-
Heller F, Florian P, Bojarski C, et al. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology 2005;129:550e64
-
(2005)
Gastroenterology
, vol.129
-
-
Heller, F.1
Florian, P.2
Bojarski, C.3
-
93
-
-
79952532799
-
Suppression of inflammation in ulcerative colitis by interferon-b-1a is accompanied by inhibition of IL-13 production
-
Mannon PJ, Hornung RL, Yang Z, et al. Suppression of inflammation in ulcerative colitis by interferon-b-1a is accompanied by inhibition of IL-13 production. Gut 2011;60:449e55
-
(2011)
Gut
, vol.60
-
-
Mannon, P.J.1
Hornung, R.L.2
Yang, Z.3
-
94
-
-
79952435375
-
Interleukins IL-33 and IL-17/IL-17A in patients with ulcerative colitis
-
Ajdukovic J, Tonkic A, Salamunic I, et al. Interleukins IL-33 and IL-17/IL-17A in patients with ulcerative colitis. Hepatogastroenterology 2010;57:1442-4
-
(2010)
Hepatogastroenterology
, vol.57
, pp. 1442-1444
-
-
Ajdukovic, J.1
Tonkic, A.2
Salamunic, I.3
-
95
-
-
72549107316
-
Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease
-
Rovedatti L, Kudo T, Biancheri P, et al. Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease. Gut 2009;58:1629-36
-
(2009)
Gut
, vol.58
, pp. 1629-1636
-
-
Rovedatti, L.1
Kudo, T.2
Biancheri, P.3
-
96
-
-
84870431806
-
Novel pharmacological approaches for inflammatory bowel disease: Targeting key intracellular pathways and the IL-23/IL-17 axis
-
Fitzpatrick LR. Novel pharmacological approaches for inflammatory bowel disease: targeting key intracellular pathways and the IL-23/IL-17 axis. Int J Inflam 2012;2012:389-404
-
(2012)
Int J Inflam
, pp. 389-404
-
-
Fitzpatrick, L.R.1
-
98
-
-
79955027327
-
Modulation of innate and adaptive immune responses by tofacitinib (CP- 690,550)
-
Ghoreschi K, Jesson MI, Lee JL, et al. Modulation of innate and adaptive immune responses by tofacitinib (CP- 690,550). J Immunol 2011;186:4234e43
-
(2011)
J Immunol
, vol.186
-
-
Ghoreschi, K.1
Jesson, M.I.2
Lee, J.L.3
-
99
-
-
84865013186
-
Tofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis
-
Sandborn WJ, Ghosh S, Panes J, et al. Tofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis. N Engl J Med 2012;367:616-24
-
(2012)
N Engl J Med
, vol.367
, pp. 616-624
-
-
Sandborn, W.J.1
Ghosh, S.2
Panes, J.3
-
100
-
-
34047186008
-
T cell costimulation: A rational target in the therapeutic armamentarium for autoimmune disease and transplantation
-
Vincenti F, Luggen M. T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune disease and transplantation. Annu Rev Med 2007;58:347e58
-
(2007)
Annu Rev Med
, vol.58
-
-
Vincenti, F.1
Luggen, M.2
-
101
-
-
35648941736
-
A phase i study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis
-
Plevy S, Salzberg B, Van Assche G, et al. A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. Gastroenterology 2007;133:1414e22
-
(2007)
Gastroenterology
, vol.133
-
-
Plevy, S.1
Salzberg, B.2
Van Assche, G.3
-
102
-
-
77949507036
-
Prospective randomized open-label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid-refractory ulcerative colitis
-
Baumgart DC, Targan SR, Dignass AU, et al. Prospective randomized open-label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid-refractory ulcerative colitis. Inflamm Bowel Dis 2010;16:620e9
-
(2010)
Inflamm Bowel Dis
, vol.16
-
-
Baumgart, D.C.1
Targan, S.R.2
Dignass, A.U.3
-
103
-
-
80053566144
-
Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis
-
Leiper K, Martin K, Ellis A, et al. Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis. Gut 2011;60:1520e6
-
(2011)
Gut
, vol.60
-
-
Leiper, K.1
Martin, K.2
Ellis, A.3
-
104
-
-
79955572862
-
DDW 2010 649: A randomized placebo-controlled trial of abatacept for moderately-to-severely active Crohn's disease (CD)
-
S-86
-
Hanauer SB, Sandborn WJ, Sands BE, et al. DDW 2010 649: a randomized placebo-controlled trial of abatacept for moderately-to-severely active Crohn's disease (CD). Gastroenterology 2010;138(Suppl 1):S-86
-
(2010)
Gastroenterology
, vol.138
, Issue.SUPPL. 1
-
-
Hanauer, S.B.1
Sandborn, W.J.2
Sands, B.E.3
-
106
-
-
0027407109
-
Endothelial-leukocyte adhesion molecules
-
Bevilacqua MP. Endothelial-leukocyte adhesion molecules. Annu Rev Immunol 1993;11:767e804
-
(1993)
Annu Rev Immunol
, vol.11
-
-
Bevilacqua, M.P.1
-
107
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11e25
-
(1992)
Cell
, vol.69
-
-
Hynes, R.O.1
-
108
-
-
77954179519
-
Anti-adhesion molecule therapy for inflammatory bowel disease
-
Ghosh S, Panaccione R. Anti-adhesion molecule therapy for inflammatory bowel disease. Ther Adv Gastroenterol 2010;3:239e58
-
(2010)
Ther Adv Gastroenterol
, vol.3
-
-
Ghosh, S.1
Panaccione, R.2
-
109
-
-
20444469332
-
Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin
-
Feagan BG, Greenberg GR, Wild G, et al. Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin. N Engl J Med 2005;352:2499e507
-
(2005)
N Engl J Med
, vol.352
-
-
Feagan, B.G.1
Greenberg, G.R.2
Wild, G.3
-
110
-
-
33646237136
-
Bioavailability and therapeutic activity of alicaforsen (ISIS 2302) administered as a rectal retention enema to subjects with active ulcerative colitis
-
Miner PB, Geary RS, Matson J, et al. Bioavailability and therapeutic activity of alicaforsen (ISIS 2302) administered as a rectal retention enema to subjects with active ulcerative colitis. Aliment Pharmacol Ther 2006;23:1427e34
-
(2006)
Aliment Pharmacol Ther
, vol.23
-
-
Miner, P.B.1
Geary, R.S.2
Matson, J.3
-
111
-
-
33646271377
-
A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis
-
van Deventer SJ, Wedel MK, Baker BF, et al. A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis. Aliment Pharmacol Ther 2006;23:1415e25
-
(2006)
Aliment Pharmacol Ther
, vol.23
-
-
Van Deventer, S.J.1
Wedel, M.K.2
Baker, B.F.3
-
112
-
-
79960336916
-
The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: A randomised study
-
Vermeire S, Ghosh S, Panes J, et al. The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: a randomised study. Gut 2011;60:1068e75
-
(2011)
Gut
, vol.60
-
-
Vermeire, S.1
Ghosh, S.2
Panes, J.3
-
113
-
-
38549137308
-
Autologous haematopoietic stem cell transplantation without CD34+ cell selection in refractory Crohn's disease
-
Cassinotti A, Annaloro C, Ardizzone S, et al. Autologous haematopoietic stem cell transplantation without CD34+ cell selection in refractory Crohn's disease. Gut 2008;57:211-17
-
(2008)
Gut
, vol.57
, pp. 211-217
-
-
Cassinotti, A.1
Annaloro, C.2
Ardizzone, S.3
-
114
-
-
80055072032
-
Immunomodulatory effects of unselected haematopoietic stem cells autrotransplantation in refractory Crohn's disease
-
Clerici M, Cassinotti A, Onida F, et al. Immunomodulatory effects of unselected haematopoietic stem cells autrotransplantation in refractory Crohn's disease. Dig Liver Dis 2011;43:946-52
-
(2011)
Dig Liver Dis
, vol.43
, pp. 946-952
-
-
Clerici, M.1
Cassinotti, A.2
Onida, F.3
-
115
-
-
78650653452
-
Autologous nonmyeloablative hematopoietic stem cell transplantation in patients with severe anti-TNF refractory Crohn disease: Long-term follow-up
-
Burt RK, Craig RM, Milanetti F, et al. Autologous nonmyeloablative hematopoietic stem cell transplantation in patients with severe anti-TNF refractory Crohn disease: long-term follow-up. Blood 2010;116:6123-32
-
(2010)
Blood
, vol.116
, pp. 6123-6132
-
-
Burt, R.K.1
Craig, R.M.2
Milanetti, F.3
-
116
-
-
78649895490
-
Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: Results of a pahse i study
-
Duijvestein M, Vos AC, Roelofs H, et al. Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a pahse I study. Gut 2010;59:1662-9
-
(2010)
Gut
, vol.59
, pp. 1662-1669
-
-
Duijvestein, M.1
Vos, A.C.2
Roelofs, H.3
-
117
-
-
48949099032
-
Long-term outcome after infliximab for refractory ulcerative colitis
-
Ferrante M, Vermeire S, Fidder H, et al. Long-term outcome after infliximab for refractory ulcerative colitis. J Crohns Colitis 2008;2:219-25
-
(2008)
J Crohns Colitis
, vol.2
, pp. 219-225
-
-
Ferrante, M.1
Vermeire, S.2
Fidder, H.3
-
118
-
-
34547503869
-
Mucosal healing in inflammatory bowel disease: Results from a Norwegian population-based cohort
-
Froslie K.F, Jahnsen J, Moum B.A, et al. Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort. Gastroenterology 2007;133:412-22
-
(2007)
Gastroenterology
, vol.133
, pp. 412-422
-
-
Froslie, K.F.1
Jahnsen, J.2
Moum, B.A.3
-
119
-
-
80053133374
-
Results from the 2nd Scientific Workshop of the ECCO. I: Impact of mucosal healing on the course of inflammatory bowel disease
-
Peyrin-Biroulet L, Ferrante M, Magro F, et al. Results from the 2nd Scientific Workshop of the ECCO. I: impact of mucosal healing on the course of inflammatory bowel disease. J Crohns Colitis 2011;5:477-83
-
(2011)
J Crohns Colitis
, vol.5
, pp. 477-483
-
-
Peyrin-Biroulet, L.1
Ferrante, M.2
Magro, F.3
-
120
-
-
10744221150
-
Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
-
Rutter M, Saunders B, Wilkinson K, et al. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 2004;126:451-9
-
(2004)
Gastroenterology
, vol.126
, pp. 451-459
-
-
Rutter, M.1
Saunders, B.2
Wilkinson, K.3
-
121
-
-
73249139677
-
Thiopurine therapy is associated with a three-fold decrease in the incidence of advanced colorectal neoplasia in IBD patients with longstanding extensive colitis: The CESAME prospective data [abstract]
-
Beaugerie L, Seksik P, Carrat F. Thiopurine therapy is associated with a three-fold decrease in the incidence of advanced colorectal neoplasia in IBD patients with longstanding extensive colitis: the CESAME prospective data [abstract]. J Crohn's Colitis 2009;3:S5
-
(2009)
J Crohn's Colitis
, vol.3
-
-
Beaugerie, L.1
Seksik, P.2
Carrat, F.3
-
122
-
-
0037434552
-
Influence of immunogenicity on the longterm efficacy of infliximab in Crohn's disease
-
Baert F, Noman M, Vermeire S, et al. Influence of immunogenicity on the longterm efficacy of infliximab in Crohn's disease. N Engl J Med 2003;348:601-8
-
(2003)
N Engl J Med
, vol.348
, pp. 601-608
-
-
Baert, F.1
Noman, M.2
Vermeire, S.3
-
123
-
-
34548130215
-
Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease
-
Vermeire S, Noman M, Van Assche G, et al. Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease. Gut 2007;56:1226-31
-
(2007)
Gut
, vol.56
, pp. 1226-1231
-
-
Vermeire, S.1
Noman, M.2
Van Assche, G.3
-
124
-
-
32044451548
-
Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
-
Hanauer SB, Sandborn WJ, Rutgeerts P, et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 2006;130:323-33
-
(2006)
Gastroenterology
, vol.130
, pp. 323-33
-
-
Hanauer, S.B.1
Sandborn, W.J.2
Rutgeerts, P.3
-
125
-
-
33846242958
-
Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
-
Colombel JF, Sandborn WJ, Rutgeerts P, et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 2007;132:52-65
-
(2007)
Gastroenterology
, vol.132
, pp. 52-65
-
-
Colombel, J.F.1
Sandborn, W.J.2
Rutgeerts, P.3
-
126
-
-
77950988234
-
Infliximab, azathioprine, or combination therapy for Crohn's disease
-
Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med 2010;62:1383-95
-
(2010)
N Engl J Med
, vol.62
, pp. 1383-1395
-
-
Colombel, J.F.1
Sandborn, W.J.2
Reinisch, W.3
-
127
-
-
33846592386
-
Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease
-
Mackey AC, Green L, Liang LC, et al. Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2007;44:265-7
-
(2007)
J Pediatr Gastroenterol Nutr
, vol.44
, pp. 265-267
-
-
MacKey, A.C.1
Green, L.2
Liang, L.C.3
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