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Volumn 91, Issue 26, 2011, Pages 1809-1812

Effects of early insulin therapy on sterol regulatory element binding protein 1 pathway and lipid accumulation in liver of type 2 diabetic rats

Author keywords

Diabete mellitus, type 2; Insulin; Steatosis; Sterol regulatory element binding protein 1

Indexed keywords

INSULIN; LIPID; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STREPTOZOCIN; SREBF1 PROTEIN, RAT;

EID: 84870472682     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2011.26.004     Document Type: Article
Times cited : (2)

References (17)
  • 1
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest, 2002, 109: 1125-1131.
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 2
    • 84870457445 scopus 로고    scopus 로고
    • Chinese source
    • 2008, 88: 848-852.
    • (2008) , vol.88 , pp. 848-852
  • 3
    • 0036788388 scopus 로고    scopus 로고
    • Effects of insulin treatment in type 2 diabetic patients on intracellular lipid content in liver and skeletal muscle
    • Anderwald C, Bernroider E, Krssak M, et al. Effects of insulin treatment in type 2 diabetic patients on intracellular lipid content in liver and skeletal muscle. Diabetes, 2002, 51: 3025-3032.
    • (2002) Diabetes , vol.51 , pp. 3025-3032
    • Anderwald, C.1    Bernroider, E.2    Krssak, M.3
  • 4
    • 33947131149 scopus 로고    scopus 로고
    • Effects of insulin therapy on liver fat content and hepatic insulin sensitivity in patients with type 2 diabetes
    • Juurinen L, Tiikkainen M, Hakkinen AM, et al. Effects of insulin therapy on liver fat content and hepatic insulin sensitivity in patients with type 2 diabetes. Am J Physiol Endocrinol Metab, 2007, 292: E829-E835.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Juurinen, L.1    Tiikkainen, M.2    Hakkinen, A.M.3
  • 5
    • 0036088366 scopus 로고    scopus 로고
    • Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content
    • Neschen S, Moore I, Regittnig W, et al. Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content. Am J Physiol Endocrinol Metab, 2002, 282: E395-E401.
    • (2002) Am J Physiol Endocrinol Metab , vol.282
    • Neschen, S.1    Moore, I.2    Regittnig, W.3
  • 6
    • 33745890321 scopus 로고    scopus 로고
    • ER stress: Can the liver cope?
    • Ji C, Kaplowitz N. ER stress: can the liver cope? J Hepatology, 2006, 45: 321-333.
    • (2006) J Hepatology , vol.45 , pp. 321-333
    • Ji, C.1    Kaplowitz, N.2
  • 7
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest, 2004, 114: 147-152.
    • (2004) J Clin Invest , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 8
    • 0043172415 scopus 로고    scopus 로고
    • The SREBP pathway-insights from Insigs and insects
    • Rawson RB. The SREBP pathway-insights from Insigs and insects. Nat Rev Mol Cell Biol, 2003, 4: 631-640.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 631-640
    • Rawson, R.B.1
  • 9
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science, 2006, 313: 1137-1140.
    • (2006) Science , vol.313 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3
  • 10
    • 2342557826 scopus 로고    scopus 로고
    • Hepatic insig-1 or -2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rats and in fasted/refed normal rats
    • Takaishi K, Duplomb L, Wang MY, et al. Hepatic insig-1 or -2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rats and in fasted/refed normal rats. Proc Natl Acad Sci U S A, 2004, 101: 7106-7111.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7106-7111
    • Takaishi, K.1    Duplomb, L.2    Wang, M.Y.3
  • 11
    • 0033598749 scopus 로고    scopus 로고
    • Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes
    • Shimomura I, Bashmakov Y, Ikemoto S, et al. Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes. Proc Natl Acad Sci U S A, 1999, 96: 13656-13661.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 13656-13661
    • Shimomura, I.1    Bashmakov, Y.2    Ikemoto, S.3
  • 12
  • 13
    • 34848851922 scopus 로고    scopus 로고
    • Angiogenesis modulates adipogenesis and obesity
    • Cao Y. Angiogenesis modulates adipogenesis and obesity. J Clin Invest, 2007, 117: 2362-2368.
    • (2007) J Clin Invest , vol.117 , pp. 2362-2368
    • Cao, Y.1
  • 14
    • 58149500277 scopus 로고    scopus 로고
    • Emerging role of adipose tissue hypoxia in obesity and insulin resistance
    • Ye J. Emerging role of adipose tissue hypoxia in obesity and insulin resistance. Int J Obes (Lond), 2009, 33: 54-66.
    • (2009) Int J Obes (Lond) , vol.33 , pp. 54-66
    • Ye, J.1
  • 15
    • 35148854599 scopus 로고    scopus 로고
    • Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice
    • Ye J, Gao Z, Yin J, et al. Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. Am J Physiol Endocrinol Metab, 2007, 293: E1118-E1128.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Ye, J.1    Gao, Z.2    Yin, J.3
  • 16
    • 60849121937 scopus 로고    scopus 로고
    • Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue
    • Yin J, Gao Z, He Q, et al. Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue. Am J Physiol Endocrinol Metab, 2009, 296: E333-E342.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Yin, J.1    Gao, Z.2    He, Q.3
  • 17
    • 77749277261 scopus 로고    scopus 로고
    • Insulin therapy stimulates lipid synthesis and improves endocrine functions of adipocytes in dietary obese C57BL/6 mice
    • Chen X, Yu QQ, Zhu YH, et al. Insulin therapy stimulates lipid synthesis and improves endocrine functions of adipocytes in dietary obese C57BL/6 mice. Acta Pharmacol Sin, 2010, 31: 341-346.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 341-346
    • Chen, X.1    Yu, Q.Q.2    Zhu, Y.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.