Lumican induces human corneal epithelial cell migration and integrin expression via ERK 1/2 signaling

Biochemical and Biophysical Research Communications

Volumn 372, Issue 1, 2008, Pages 221-225

  Seomun, Young ^a   Joo, Choun Ki ^a  

^a University of Medicine   (South Korea)

Author keywords

Corneal epithelial cells; ERK 1 2; Integrin; Lumican; Migration

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALPHA2 INTEGRIN; BETA1 INTEGRIN; LUMICAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CORNEA EPITHELIUM; ENZYME ACTIVATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGENS, CD29; BUTADIENES; CELL LINE; CELL MOVEMENT; EPITHELIUM, CORNEAL; HUMANS; INTEGRIN ALPHA2; KERATAN SULFATE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRILES; PROTEIN KINASE INHIBITORS; PROTEOCHONDROITIN SULFATES; SIGNAL TRANSDUCTION;

MUS;

EID: 44649191702     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.05.014     Document Type: Article

References (23)

1. Hay E.D. Development of the vertebrate cornea. Int. Rev. Cytol. 63 (1980) 263-322
2. Scott J.E. Proteodermatan and proteokeratan sulfate (decorin, Lumican/fibromodulin) proteins are horseshoe shaped. Implications for their interactions with collagen. Biochemistry 35 (1996) 8795-8799
3. Rawe I.M., Tuft S.J., and Meek K.M. Proteoglycan and collagen morphology in superficially scarred rabbit cornea. Histochem. J. 24 (1992) 311-318
4. Hassel J.R., Kimura J.H., and Hascall V.C. Proteoglycan core protein families. Annu. Rev. Biochem. 55 (1986) 539-567
5. Corpus L.M., Funderburgh J.L., Funderburgh M.L., Bottomley G.S., Prakash S., and Conrad G.W. Molecular cloning and tissue distribution of keratocan. Bovine corneal keratan sulfate proteoglycan 37A. J. Biol. Chem. 271 (1996) 9759-9763
6. Nilsson B., Nakazawa K., Hassell J.R., Newsome D.A., and Hascall V.C. Structure of oligosaccharides and their linkage region between keratan sulfate and the core protein of proteoglycans from monkey cornea. J. Biol. Chem. 258 (1983) 6056-6063
7. Blochberger T.C., Vergnes J.-P., Hempel J., and Hassell J.R. cDNA to chick lumican (corneal keratan sulfate proteoglycan) reveals homology to the small interstitial proteoglycan gene family and expression in muscle and intestine. J. Biol. Chem. 267 (1992) 347-352
8. Funderburgh J.L., Corpus L.M., Roth M.R., Funderburgh M.L., Tasheva E.S., and Conrad G.W. Mimecan, the 25-kDa corneal keratan sulfate proteoglycan, is a product of the gene producing osteoglycin. J. Biol. Chem. 272 (1997) 28089-28095
9. Funderburgh J.L., Hevelone D.N., Mary R.R., Funderburgh M.L., Rodrigues M.R., Nirankari V.S., and Conrad G.W. Decorin and Biglycan of Normal and Pathologic Human Corneas. Invest. Ophthalmol. Vis. Sci. 39 (1998) 1957-1964
10. Bredrup C., Knappskog P.M., Majewski J., Rødahl E., and Boman H. Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene. Invest. Ophthalmol. Vis. Sci. 46 (2005) 420-426
11. Chakravarti S., Magnuson T., Lass J.H., Jepsen K.J., LaMantia C., and Carroll H. Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J. Cell Biol. 141 (1998) 1277-1286
12. Chakravarti S., Petroll W.M., Hassell J.R., Jester J.V., Lass J.H., Paul J., and Birk D.E. Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stroma. Invest. Ophthalmol. Vis. Sci. 41 (2000) 3365-3373
13. Song J., Lee Y.G., Houston J., Petroll W.M., Chakravarti S., Cavanagh H.D., and Jester J.V. Neonatal corneal stromal development in the normal and lumican-deficient mouse. Invest. Ophthalmol. Vis. Sci. 44 (2003) 548-557
14. Saika S., Shiraishi A., Saika S., Liu C.Y., Junderburgh J.L., and Kao W.W. Role of lumican in the corneal epithelium during wound healing. J. Biol. Chem. 275 (2000) 2607-2612
15. Yeh L.K., Chen W.L., Li W., Espana E.M., Ouyang J., Kawakita T., Kao W.W., Tseng S.C., and Liu C.Y. Soluble lumican glycoprotein purified from human amniotic membrane promotes corneal epithelial wound healing. Invest. Ophthalmol. Vis. Sci. 46 (2005) 479-486
16. Lyu J.M., Lee K.S., and Joo C.K. Transactivation of EGFR mediates insulin-stimulated ERK 1/2 activation and enhanced cell migration in human corneal epithelial cells. Mol. Vis. 12 (2006) 1403-1410
17. Naito Z. The role of small leucine-rich proteoglycan (SLRP) family in pathological lesions and cancer cell growth. J. Nippon Med. Sch. 72 (2005) 137-145
18. Nikitovic D., Berdiaki A., Zafiropoulos A., Katonis P., Tsatsakis A., Karamanos N.K., and Tzanakakis G.N. Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells. FEBS J. 275 (2008) 350-361
19. Brézillon S., Venteo L., Ramont L., D'Onofrio M.F., Perreau C., Pluot M., Maquart F.X., and Wegrowski Y. Expression of lumican, a small leucine-rich proteoglycan with antitumour activity, in human malignant melanoma. Clin. Exp. Dermatol. 32 (2007) 405-416
20. Lu Y.P., Ishiwata T., Kawahara K., Watanabe M., Naito Z., Moriyama Y., Sugisaki Y., and Asano G. Expression of lumican in human colorectal cancer cells. Pathol. Int. 52 (2002) 519-526
21. Hassel J.R., Newsome D.A., Krachmer J.H., and Rodrigues M.M. Macular corneal dystrophy: failure to synthesize a mature keratan sulfate proteoglycan. Proc. Natl. Acad. Sci. USA 77 (1980) 3705-3709
22. Majava M., Bishop P.N., Hägg P., Scott P.G., Rice A., Inglehearn C., Hammond C.J., Spector T.D., Ala-Kokko L., and Männikkö M. Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia. Hum. Mutat. 28 (2007) 336-344
23. D'Onofrio M.-F., Brézillon S., Baranek T., Perreau C., Roughley P.J., Maquart F.X., and Wegrowski Y. Identification of β1 integrin as mediator of melanoma cell adhesion to lumican. Biochem. Biophys. Res. Commun. 365 (2008) 266-272