Lumican is required for neutrophil extravasation following corneal injury and wound healing

Journal of Cell Science

Volumn 123, Issue 17, 2010, Pages 2987-2995

  Hayashi, Yasuhito ^a,b   Call, Mindy K ^a   Chikama, Tai Ichiro ^a   Liu, Hongshan ^a   Carlson, Eric C ^c   Sun, Yan ^c   Pearlman, Eric ^c   Funderburgh, James L ^d   Babcock, George ^e   Liu, Chia Yang ^a   Ohashi, Yuichi ^b   Kao, Winston W Y ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Cornea; Knockout mouse; Lumican; Neutrophil; Transgenic mouse; Wound healing

Indexed keywords

CASEIN; LUMICAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA INJURY; CORNEA STROMA; EXTRAVASATION; INFLAMMATION; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; WOUND HEALING;

ANIMALS; CHONDROITIN SULFATE PROTEOGLYCANS; CORNEA; CORNEAL DISEASES; EPITHELIUM, CORNEAL; EYE INJURIES; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; KERATAN SULFATE; MICE; NEUTROPHILS; PERITONEAL LAVAGE; WOUND HEALING;

MUS; MUS MUSCULUS;

EID: 77956891991     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.068221     Document Type: Article

References (31)

1. Bunting, M., Harris, E. S., McIntyre, T. M., Prescott, S. M. and Zimmerman, G. A. (2002). Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands. Curr. Opin. Hematol. 9, 30-35.
2. Carlson, E. C., Liu, C. Y., Chikama, T., Hayashi, Y., Kao, C. W., Birk, D. E., Funderburgh, J. L., Jester, J. V. and Kao, W. W. (2005). Keratocan, a cornea-specific keratan sulfate proteoglycan, is regulated by lumican. J. Biol. Chem. 280, 25541-25547.
3. Carlson, E. C., Lin, M., Liu, C. Y., Kao, W. W., Perez, V. L. and Pearlman, E. (2007). Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1. J. Biol. Chem. 282, 35502-35509.
4. Chakravarti, S., Magnuson, T., Lass, J. H., Jepsen, K. J., LaMantia, C. and Carroll, H. (1998). Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J. Cell Biol. 141, 1277-1286. (Pubitemid 28265620)
5. Ezura, Y., Chakravarti, S., Oldberg, A., Chervoneva, I. and Birk, D. E. (2000). Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons. J. Cell Biol. 151, 779-788.
6. Funderburgh, J. L., Funderburgh, M. L., Mann, M. M. and Conrad, G. W. (1991). Arterial lumican. Properties of a corneal-type keratan sulfate proteoglycan from bovine aorta. J. Biol. Chem. 266, 24773-24777.
7. Funderburgh, J. L., Funderburgh, M. L., Brown, S. J., Vergnes, J. P., Hassell, J. R., Mann, M. M. and Conrad, G. W. (1993). Sequence and structural implications of a bovine corneal keratan sulfate proteoglycan core protein. Protein 37B represents bovine lumican and proteins 37A and 25 are unique. J. Biol. Chem. 268, 11874-11880.
8. Funderburgh, J. L., Mitschler, R. R., Funderburgh, M. L., Roth, M. R., Chapes, S. K. and Conrad, G. W. (1997). Macrophage receptors for lumican. A corneal keratan sulfate proteoglycan. Invest. Ophthalmol. Vis. Sci. 38, 1159-1167.
9. Kao, W. W. and Liu, C. Y. (2002). Roles of lumican and keratocan on corneal transparency. Glycoconj. J. 19, 275-285.
10. Kao, W. W., Funderburgh, J. L., Xia, Y., Liu, C. Y. and Conrad, G. W. (2006). Focus on molecules: lumican. Exp. Eye Res. 82, 3-4.
11. Krull, N. B. and Gressner, A. M. (1992). Differential expression of keratan sulphate proteoglycans fibromodulin, lumican and aggrecan in normal and fibrotic rat liver. FEBS Lett. 312, 47-52.
12. Lee, S., Bowrin, K., Hamad, A. R. and Chakravarti, S. (2009). Extracellular matrix lumican deposited on the surface of neutrophils promotes migration by binding to beta2 integrin. J. Biol. Chem. 284, 23662-23669.
13. Leygue, E., Snell, L., Dotzlaw, H., Hole, K., Hiller-Hitchcock, T., Roughley, P. J., Watson, P. H. and Murphy, L. C. (1998). Expression of lumican in human breast carcinoma. Cancer Res. 58, 1348-1352.
14. Lin, M., Carlson, E., Diaconu, E. and Pearlman, E. (2007). CXCL1/KC and CXCL5/LIX are selectively produced by corneal fibroblasts and mediate neutrophil infiltration to the corneal stroma in LPS keratitis. J. Leukoc. Biol. 81, 786-792.
15. Lu, Y. P., Ishiwata, T., Kawahara, K., Watanabe, M., Naito, Z., Moriyama, Y., Sugisaki, Y. and Asano, G. (2002). Expression of lumican in human colorectal cancer cells. Pathol. Int. 52, 519-526.
16. Matsuda, Y., Yamamoto, T., Kudo, M., Kawahara, K., Kawamoto, M., Nakajima, Y., Koizumi, K., Nakazawa, N., Ishiwata, T. and Naito, Z. (2008). Expression and roles of lumican in lung adenocarcinoma and squamous cell carcinoma. Int. J. Oncol. 33, 1177-1185.
17. Meij, J. T., Carlson, E. C., Wang, L., Liu, C. Y., Jester, J. V., Birk, D. E. and Kao, W. W. (2007). Targeted expression of a lumican transgene rescues corneal deficiencies in lumican-null mice. Mol. Vis. 13, 2012-2018.
18. Merlin, D., Sitaraman, S., Liu, X., Eastburn, K., Sun, J., Kucharzik, T., Lewis, B. and Madara, J. L. (2001). CD98-mediated links between amino acid transport and beta 1 integrin distribution in polarized columnar epithelia. J. Biol. Chem. 276, 39282-39289.
19. Nemzek, J. A., Bolgos, G. L., Williams, B. A. and Remick, D. G. (2001). Differences in normal values for murine white blood cell counts and other hematological parameters based on sampling site. Inflamm. Res. 50, 523-527.
20. Reigle, K. L., Di L. G., Turner, K. R., Last, J. A., Chervoneva, I., Birk, D. E., Funderburgh, J. L., Elrod, E., Germann, M. W., Surber, C. et al. (2008). Non-enzymatic glycation of type I collagen diminishes collagen-proteoglycan binding and weakens cell adhesion. J. Cell Biochem. 104, 1684-1698.
21. Saika, S., Shiraishi, A., Liu, C. Y., Funderburgh, J. L., Kao, C. W., Converse, R. L. and Kao, W. W. (2000). Role of lumican in the corneal epithelium during wound healing. J. Biol. Chem. 275, 2607-2612.
22. Saika, S., Kono-Saika, S., Ohnishi, Y., Sato, M., Muragaki, Y., Ooshima, A., Flanders, K. C., Yoo, J., Anzano, M., Liu, C. Y. et al. (2004). Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury. Am. J. Pathol. 164, 651-663.
23. Sato, S., Ouellet, N., Pelletier, I., Simard, M., Rancourt, A. and Bergeron, M. G. (2002). Role of galectin-3 as an adhesion molecule for neutrophil extravasation during streptococcal pneumonia. J. Immunol. 168, 1813-1822.
24. Sun, Y., Hise, A. G., Kalsow, C. M. and Pearlman, E. (2006). Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88. Infect. Immun. 74, 5325-5332.
25. Suratt, B. T., Young, S. K., Lieber, J., Nick, J. A., Henson, P. M. and Worthen, G. S. (2001). Neutrophil maturation and activation determine anatomic site of clearance from circulation. Am. J. Physiol. Lung Cell Mol. Physiol. 281, L913-L921. (Pubitemid 32948175)
26. Vij, N., Roberts, L., Joyce, S. and Chakravarti, S. (2005). Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling. Invest. Ophthalmol. Vis. Sci. 46, 88-95.
27. Werr, J., Xie, X., Hedqvist, P., Ruoslahti, E. and Lindbom, L. (1998). beta1 integrins are critically involved in neutrophil locomotion in extravascular tissue in vivo. J. Exp. Med. 187, 2091-2096. (Pubitemid 28285579)
28. Williams, R. N., Paterson, C. A., Eakins, K. E. and Bhattacherjee, P. (1982). Quantification of ocular inflammation: evaluation of polymorphonuclear leucocyte infiltration by measuring myeloperoxidase activity. Curr. Eye Res. 2, 465-470.
29. Wu, Q., Martin, R. J., Rino, J. G., Breed, R., Torres, R. M. and Chu, H. W. (2007). IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes. Infect. 9, 78-86.
30. Yeh, L. K., Chen, W. L., Li, W., Espana, E. M., Ouyang, J., Kawakita, T., Kao, W. W., Tseng, S. C. and Liu, C. Y. (2005). Soluble lumican glycoprotein purified from human amniotic membrane promotes corneal epithelial wound healing. Invest. Ophthalmol. Vis. Sci. 46, 479-486.
31. Ying, S., Shiraishi, A., Kao, C. W., Converse, R. L., Funderburgh, J. L., Swiergiel, J., Roth, M. R., Conrad, G. W. and Kao, W. W. (1997). Characterization and expression of the mouse lumican gene. J. Biol. Chem. 272, 30306-30313.