Lumican regulates osteosarcoma cell adhesion by modulating TGFβ2 activity

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 6, 2011, Pages 928-935

  Nikitovic, Dragana ^a   Chalkiadaki, Georgia ^a   Berdiaki, Aikaterini ^a   Aggelidakis, John ^b   Katonis, Pavlos ^b   Karamanos, Nikos K ^c   Tzanakakis, George N ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^c UNIVERSITY OF PATRAS   (Greece)

Author keywords

1 integrin; FAK; Lumican; Osteosarcoma cell adhesion; pSmad; TGF 2

Indexed keywords

BETA1 INTEGRIN; FIBRONECTIN; LUMICAN; SMAD2 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA2;

ARTICLE; CELL ADHESION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; PROTEIN EXPRESSION;

ANTIGENS, CD29; CELL ADHESION; CELL LINE, TUMOR; CHONDROITIN SULFATE PROTEOGLYCANS; ENZYME ACTIVATION; FIBRONECTINS; FOCAL ADHESION KINASE 2; HUMANS; KERATAN SULFATE; OSTEOSARCOMA; PEPTIDE FRAGMENTS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; TRANSCRIPTIONAL ACTIVATION; TRANSFORMING GROWTH FACTOR BETA2;

EID: 79955916547     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2011.03.008     Document Type: Article

References (45)

1. H. Baba, T. Ishiwata, E. Takashi, G. Xu, and G. Asano Expression and localization of lumican in the ischemic and reperfused rat heart Japanese Circulation Journal 65 2001 445 450
2. D. Benayahu, I. Shur, I. Meller, and J. Issakow Cellular and molecular properties associated with osteosarcoma cells Journal of Cell Biochemistry 84 1998 108 114
3. T.C. Blochberger, P.K. Cornuet, and J.R. Hassell Isolation and partial characterization of lumican and decorin from adult chicken corneas. A keratan sulfate-containing isoform of decorin is developmentally regulated Journal of Biological Chemistry 267 1992 20613 20619
4. S. Brezillon, C. Zeltz, L. Schneider, C. Terryn, B. Vuillermoz, and L. Ramont Lumican inhibits B16F1 melanoma cell lung metastasis Journal of Physiology and Pharmacology 60 Suppl. 4 2009 15 22
5. S. Chakravarti, T. Magnuson, L.H. Lass, K.J. Jepsen, C. LaMantia, and H. Carroll Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican Journal of Cell Biology 141 1998 1277 1286 (Pubitemid 28265620)
6. X.D. Chen, L.W. Fisher, P.G. Robey, and M.F. Young The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation FASEB Journal 18 2004 948 958 (Pubitemid 38787591)
7. S.L. Cheng, C.F. Lai, A. Fausto, M. Chellaiah, X. Feng, and K.P. McHugh Regulation of alphaVbeta3 and alphaVbeta5 integrins by dexamethasone in normal human osteoblastic cells Journal of Cell Biochemistry 77 2000 265 276 (Pubitemid 30176655)
8. M. Dolhnikoff, J. Morin, P.J. Roughley, and M.S. Ludwig Expression of lumican in human lungs American Journal of Respiratory Cell and Molecular Biology 19 1998 582 587 (Pubitemid 128354239)
9. A. Franchi, L. Arganini, G. Baroni, A. Calzolari, R. Capanna, and D. Campanacci Expression of transforming growth factor beta isoforms in osteosarcoma variants: association of TGF beta 1 with high-grade osteosarcomas Journal of Pathology 185 1998 284 289 (Pubitemid 28320050)
10. E. Fransvea, A. Mazzocca, A. Santamato, A. Azzariti, S. Antonaci, and G. Giannelli Kinase activation profile associated with TGF-β-dependent migration of HCC cells: a preclinical study Cancer Chemotherapy and Pharmacology 2010 September 16 [Epub ahead of print]
11. J.L. Funderburgh, M.L. Funderburgh, M.M. Mann, and G.W. Conrad Arterial lumican. Properties of a corneal-type keratan sulphate proteoglycan from bovine aorta Journal of Biological Chemistry 266 1991 24773 24777 (Pubitemid 21909008)
12. G. Giannelli, A. Mazzocca, E. Fransvea, M. Lahn, and S. Antonaci Inhibiting TGF-β signaling in hepatocellular carcinoma Biochemical and Biophysical Acta 2010 December 1 [Epub ahead of print]
13. V.L. Gassling, Y. Ail, I.N. Springer, N. Hubert, and J. Wiltfang Platelet-rich plasma and platelet-rich fibrin in human cell culture Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 108 2009 48 55
14. J. Grover, X.N. Chen, J.R. Korenberg, and P.J. Roughley The human lumican gene. Organization, chromosomal location, and expression in articular cartilage Journal of Biological Chemistry 270 1995 21942 21949 1995
15. I.K. Hong, Y.J. Jin, H.J. Byun, D.I. Jeoung, Y.M. Kim, and H. Lee Homophilic interactions of Tetraspanin CD151 up-regulate motility and matrix metalloproteinase-9 expression of human melanoma cells through adhesion-dependent c-Jun activation signaling pathways Journal of Biological Chemistry 281 2006 24279 24292 (Pubitemid 44274201)
16. D.D. Hu, E.C. Lin, N.L. Kovach, J.R. Hoyer, and J.W. Smith A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5 Journal of Biological Chemistry 270 1995 26232 26238
17. R.V. Iozzo The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth Critical Reviews in Biochemistry and Molecular Biology 32 1997 141 174 (Pubitemid 27209329)
18. T. Ishiwata, T. Yamamoto, K. Kawahara, Y. Kawamoto, Y. Matsuda, and S. Ishiwata Enhanced expression of lumican inhibited the attachment and growth of human embryonic kidney 293 cells Experimental and Molecular Pathology 88 2010 363 370
19. W.W. Kao Ocular surface tissue morphogenesis in normal and disease states revealed by genetically modified mice Cornea 25 Suppl. 1 2006 S7 S19
20. M.A. Karsdal, M.S. Fjording, N.T. Foged, J.M. Delaissé, and A. Lochter Transforming growth factor-beta-induced osteoblast elongation regulates osteoclastic bone resorption through a p38 mitogen-activated protein kinase- and matrix metalloproteinase-dependent pathway Journal of Biological Chemistry 276 2001 39350 39358
21. H. Kizawa, I. Kou, A. Iida, A. Sudo, Y. Miyamoto, and A. Fukuda Nature Genetics 37 2005 138 144
22. C.F. Lai, X. Feng, R. Nishimura, S.L. Teitelbaum, L.V. Avioli, and F.P. Ross Transforming growth factor-beta up-regulates the beta 5 integrin subunit expression via Sp1 and Smad signalling Journal of Biological Chemistry 275 2000 36400 36406
23. E. Leygue, L. Snell, H. Dotzlaw, K. Hole, T. Hiller-Hitchcock, and P.J. Roughley Expression of lumican in human breast carcinoma Cancer Research 58 1998 1348 1352 (Pubitemid 28193587)
24. Y. Matsuda, T. Yamamoto, M. Kudo, K. Kawahara, M. Kawamoto, and Y. Nakajima Expression and roles of lumican in lung adenocarcinoma and squamous cell carcinoma International Journal of Oncology 33 2008 1177 1185
25. K. Miyazono, A. Olofsson, P. Colosetti, and C.H. Heldin A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1 EMBO Journal 10 1991 1091 1101 (Pubitemid 21905570)
26. Y. Mochida, D. Parisuthiman, M. Kaku, J. Hanai, V.P. Sukhatme, and M. Yamauchi Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling Journal of Biological Chemistry 281 2006 36044 36051 (Pubitemid 46041337)
27. Z. Naito The role of small leucine-rich proteoglycan (SLRP) family in pathological lesions and cancer cell growth Journal of Nippon Medical School 72 2005 137 145 (Pubitemid 40943770)
28. S. Nakayamada, Y. Okada, K. Saito, M. Tamura, and Y. Tanaka Beta1 integrin/focal adhesion kinase-mediated signaling induces intercellular adhesion molecule 1 and receptor activator of nuclear factor kappaB ligand on osteoblasts and osteoclast maturation Journal of Biological Chemistry 278 2003 45368 45374 (Pubitemid 37432673)
29. L.J. Nesti, E.J. Caterson, M. Wang, R. Chang, F. Chapovsky, and J.B. Hoek TGF-beta1 calcium signaling increases alpha5 integrin expression in osteoblasts Journal of Orthopaedic Research 20 2002 1042 1049
30. D. Nikitovic, A. Berdiaki, A. Zafiropoulos, P. Katonis, A. Tsatsakis, and N.K. Karamanos Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells FEBS Journal 275 2008 350 361
31. K. Ohta, G. Lupo, S. Kuriyama, R. Keynes, C.E. Holt, and W.A. Harris Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin Developmental Cell 7 2004 347 358 (Pubitemid 39232971)
32. H. Qin, T. Ishiwata, and G. Asano Effects of the extracellular matrix on lumican expression in rat aortic smooth muscle cells in vitro Journal of Pathology 195 1999 604 608
33. A. Raouf, B. Ganss, C. McMahon, C. Vary, P.J. Roughley, and A. Seth Lumican is a major proteoglycan component of the bone matrix Matrix Biology 4 2002 361 367 (Pubitemid 34786472)
34. D.B. Rifkin Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability Journal of Biological Chemistry 280 2005 7409 7412 (Pubitemid 40349631)
35. S. Saika, A. Shiraishi, C.Y. Liu, J.L. Funderburgh, C.W. Kao, and R.L. Converse Role of lumican in the corneal epithelium during wound healing Journal of Biological Chemistry 275 2000 2607 2612 (Pubitemid 30082027)
36. L. Schaefer, H.J. Grone, I. Raslik, H. Robenek, J. Ugorcakova, and S. Budny Small proteoglycans of normal adult human kidney: distinct expression patterns of decorin, biglycan, fibromodulin, and lumican Kidney International 58 2000 1557 1568
37. M. Ständer, U. Naumann, L. Dumitrescu, M. Heneka, P. Löschmann, and E. Gulbins Decorin gene transfer-mediated suppression of TGF-beta synthesis abrogates experimental malignant glioma growth in vivo Gene Therapy 5 1998 1187 1194 (Pubitemid 28448426)
38. M. Ständer, U. Naumann, W. Wick, and M. Weller Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth Cell Tissue Research 296 1999 221 227 (Pubitemid 29219174)
39. R. Sztrolovics, M. Alini, J.S. Mort, and P.J. Roughley Age related changes in fibromodulin and lumican in human intervertebral discs Spine 24 1999 1765 1771 (Pubitemid 29426668)
40. Y. Tamura, Y. Takeuchi, M. Suzawa, S. Fukumoto, M. Kato, and K. Miyazono Focal adhesion kinase activity is required for bone morphogenetic protein - Smad1 signaling and osteoblastic differentiation in murine MC3T3-E1 cells Journal of Bone Mineral Research 16 2001 1772 1779 (Pubitemid 32911482)
41. S. Troup, C. Njue, E.V. Kliewer, M. Parisien, C. Roskelley, and S. Chakravarti Reduced expression of the small leucine-rich proteoglycans, lumican, and decorin is associated with poor outcome in node-negative invasive breast cancer Clinical Cancer Research 9 2003 207 214 (Pubitemid 36109735)
42. K.E. Yao, J. Tan, P. Ye, K. Wang, W. Xu, and X. ShenTu Integrin beta1-mediated signaling is involved in transforming growth factor-beta2- promoted migration in human lens epithelial cells Molecular Vision 13 2007 1769 1776 (Pubitemid 47496779)
43. M.F. Young, Y. Bi, L. Ameye, and X.D. Chen Biglycan knockout mice: new models for musculoskeletal diseases Glycoconjugate Journal 19 2002 257 262 (Pubitemid 37174553)
44. Y. Yu, R.I. Harris, J.L. Yang, H.C. Anderson, and Walsh WR Differential expression of osteogenic factors associated with osteoinductivity of human osteosarcoma cell lines Journal of Biomedical Material Research A 70 2004 122 128 (Pubitemid 38849819)
45. C. Zeltz, S. Brézillon, J. Käpylä, J.A. Eble, H. Bobichon, and C. Terryn Lumican inhibits cell migration through α2β1 integrin Experimental Cell Research 316 2010 2922 2931