Enhanced absorption of hydroxysafflor yellow A using a self-double-emulsifying drug delivery system: In vitro and in vivo studies

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 4099-4107

  Lv, Liang Zhong ^a   Tong, Chen Qi ^a   Lv, Qing ^b,c   Tang, Xin Jiang ^b   Li, Li Ming ^b   Fang, Qing Xia ^a   Yu, Jia ^a   Han, Min ^b   Gao, Jian Qing ^b  

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Bioavailability; Caco 2; Cells; Histopathologic studies; Hydroxysafflor yellow A; Self double emulsifying drug delivery system

Indexed keywords

HYDROXYSAFFLOR YELLOW A; MULTIDRUG RESISTANCE PROTEIN; PLANT MEDICINAL PRODUCT; RHODAMINE 123; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BIOACCUMULATION; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DOUBLE EMULSIFYING DRUG DELIVERY SYSTEM; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; EMULSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PARTICLE SIZE; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; WATER IN OIL IN WATER DOUBLE EMULSION;

ABSORPTION; ANALYSIS OF VARIANCE; ANIMALS; AREA UNDER CURVE; CACO-2 CELLS; CELL SURVIVAL; CHALCONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; EMULSIONS; HUMANS; INTESTINAL MUCOSA; MALE; NANOPARTICLES; QUINONES; RATS; RATS, SPRAGUE-DAWLEY; RHODAMINES;

CARTHAMUS TINCTORIUS; RATTUS;

EID: 84870387426     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S33398     Document Type: Article

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