Guanxin II for the management of coronary heart disease

Chinese Journal of Integrative Medicine

Volumn 15, Issue 6, 2009, Pages 472-476

  Qin, Feng ^a   Huang, Xi ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Adverse event; Coronary heart disease; Guanxin II; Pharmacoeconomic assessment; Pharmacokinetics; Pharmacology; Quality control

Indexed keywords

AMLODIPINE; CHINESE DRUG; DILTIAZEM; FERULIC ACID; GUANXIN II; PROTOCATECHUALDEHYDE; RANOLAZINE; TANSHINOL; UNCLASSIFIED DRUG; GUANXIN NO. 2; HERBACEOUS AGENT;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; CHINESE MEDICINE; CONSTIPATION; COST EFFECTIVENESS ANALYSIS; DRUG COST; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; HEART PROTECTION; HUMAN; HYDROXYSAFFLOR YELLOW A; ISCHEMIC HEART DISEASE; PHARMACOECONOMICS; PRIORITY JOURNAL; REVIEW; SAFFLOWER; TREATMENT OUTCOME; XEROSTOMIA; CORONARY ARTERY DISEASE;

CORONARY DISEASE; DRUGS, CHINESE HERBAL; ECONOMICS, PHARMACEUTICAL; HUMANS;

EID: 73849148814     PISSN: 16720415     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11655-009-0472-6     Document Type: Review

References (59)

1. Cheng JW. Ranolazine for the management of coronary artery disease. Clin Ther 2006;28:1996-2007. (Pubitemid 46215744)
2. Nabel EG. Cardiovascular disease. N Engl J Med 2003;349:60-72.
3. Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, et al. Heart disease and stroke statistics - 2006 update. A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2006;113:85-151.
4. Abrams J. Clinical practice. Chronic stable angina. N Engl J Med 2005;352:2524-2533.
5. Chen KJ, Qian ZZ, Liu WL. Observation on long-term effects of Guanxin II in treating 164 patients with angina pectoris of coronary heart disease. J Cardiovasc Dis (Chin) 1978;6:22-24.
6. Zhao J, Huang X, Tang W, Ren P, Xing Z, Tian X, et al. Effect of oriental herbal prescription Guan-Xin-Er-Hao on coronary flow in healthy volunteers and anti-apoptosis on myocardial ischemia-reperfusion in rat models. Phytother Res 2007;21:926-931. (Pubitemid 47582765)
7. Makino T, Wakushima H, Okamoto T, Okukubo Y, Deguchi Y, Kano Y. Pharmacokinetic interactions between warfarin and kangen-karyu, a Chinese traditional herbal medicine, and their synergistic action. J Ethnopharmacol 2002;82:35-40. (Pubitemid 34886574)
8. The Pharmacopoeia of the People's Republic of China. 2005 ed. Vol.1. Beijng: Chemical Industry Press; 2005:653-654.
9. Huang J, Tian J, Zhu W. Content determination of danshensu and protocatechuic aidehyde contents of Salvia Milfiorrhiza and Coronary Heart No II Decoction in different decocting methods by HPLC respectively. Chin J Inf Tradit Chin Med (Chin) 2005;12:44-46.
10. Gan HQ, Huang X, Qu Y, Ren P, Zhang S, Mei Q. Simultaneous determination of danshensu, protocatechuic aldehyde, paeoniflorin and ferulic acid in Guan-Xin- II Decoction by RP-HPLC. J Fourth Milit Med Univ (Chin) 2004;25:772-775.
11. Gan HQ, Mei QB, Qu Y, Huang X. Quality study on Guanxin II Decoction. Chin Pharm (Chin) 2005;16:1695-1696.
12. Wang LL, Huang X, Ren P, Zhang L, Zhang HX. Determination of contents of paeoniflorin and ferulic acid in No. 2 Decoction of coronary heart by reversed phase supercritical fluid extraction and chromatography. J Chengdu Univ Tradit Chin Med (Chin) 2001;24:51-52.
13. Wang J, Feng W, Tong Y, Yan J, Wang Z, Zhu X, et al. Comparative studies on the purifying conditions of the elixation of the Guanxin II Decoction. Chin J Exp Tradit Med Form (Chin) 2007;13:14-16.
14. Tong Y, Wang J, Feng W, Yan J, Wang Z, Zhu X, et al. Effect of the two kinds of decocting methods on contents of main active components in Guanxin II Decoctions. Chin J Exp Tradit Med Form (Chin) 2007;13:24-26.
15. Qiao X, Han J, Xu M, Zhang ZC, Sun SF, Li HF, et al. Characterization of chemical constituents in Guan Xin II Decoction by liquid chromatography coupled with electrospray ionization-mass spectrometry. Planta Med 2008;74:1720-1729.
16. Qiao X, Xu M, Han J, Guo DA. Progresses: constituents and pharmacological analyses of Guan Xin Er Hao Decoction. World Sci Tech-Mod Tradit Chin Med (Chin) 2007;9:86-95.
17. Qin F, Huang X, Zhang HM, Ren P. Pharmacokinetic comparison of puerarin after oral administration of Jiawei-Xiaoyao-San in healthy volunteers and functional dyspepsia patients: influence of disease state. J Pharm Pharmacol 2009;61:125-129.
18. Gan HQ, Mei QB, Wang Y, Huang X. Serum pharmacochemistry changes of Guanxin II Oral Decoction in healthy volunteers. Chin Pharm (Chin) 2006;17:173-177.
19. Ye G, Li YZ, Li YY, Guo HZ, Guo DA. SPE-HPLC method for the determination and pharmacokinetic studies on paeoniflorin in rat serum after oral administration of traditional Chinese medicinal preparation Guan-Xin-Er-Hao Decoction. J Pharm Biomed Anal 2003;33:521-527. (Pubitemid 37206476)
20. Hu Y, Chen W, Zhang Y, Li L, Zhang GM, Yang W, et al. Degradation of paeoniflorin in Guanxin II prescription by intestinal bacteria. Chin Pharm J (Chin) 2007;42:1813-1818.
21. Yang XG, Peng B, Zhang GH, Wei LL, Nie SF, Pan WS. Studies of the pharmacokinetics of paeoniflorin in two Jing-Zhi-Guan-Xin formulations after oral administration to beagle dogs. J Pharm Biomed Anal 2006;41:320-324.
22. Gan HQ, Mei QB, Zhu W, Huang X. Pharmacokinetics of ferulic acid in serum of healthy male volunteers after oral administration of Guanxin II Decoction. Chin Pharm (Chin) 2007;18:109-111.
23. Ren P, Huang X, Chen K, Zhang L, Wang LL, Ma XC. Comparison of ferulic acid concentration-time profiles absorbed into serum between oral ligusticum wallichi and Guanxin II Decoctions. Chin Heart J (Chin) 2000;12:253-254.
24. Huang X, Qin F, Zhang HM, Xiao HB, Wang LX, Zhang XY. Cardioprotection by Guanxin II in rats with acute myocardial infarction is related to its three compounds. J Ethnopharmacol 2009;121:268-273.
25. Zeng X, He H, Yang J, Yang X, Wu L, Yu J. Temporal effect of Guanxin No. 2 on cardiac function, blood viscosity and angiogenesis in rats after long-term occlusion of the left anterior descending coronary artery. J Ethnopharmacol 2008;118:485-494.
26. Gan HQ, Huang X, Tian XQ, Zhu YS, Zhang SH, Li J, et al. Effect of oral administration of Guanxin II Decoction on coronary blood flow and cardiac systolic/diastolic function in healthy males. Chin J Integr Tradit West Med (Chin) 2004;24:785-789.
27. Tian X, Qian Y, Huang X, Zhu Y, Gan H, Li J, et al. Evaluating effects of Guan-Xin-Er-Hao Decoction on coronary artery hemodynamics in healthy men using coronary artery flow imaging. Chin J Ultrasound Med (Chin) 2004;20:936-939.
28. Tang W, Chen D, Huang X, Ren P, Xia Q, Wan M, et al. Effect of Coronary Heart No. 2 on the hemodynamics of inferior mesentery artery in healthy male volunteers. Chin J Exp Tradit Med Form (Chin) 2006;12:70-72.
29. Xu LN, Yin ZZ, Ou YR. The effect of compositus Guan-Xin No. 2 on myocardial ischemia and hypoxia in experimental animals. Atca Pharm Sin (Chin) 1979;14:461-466.
30. Zhao HW, Qin F, Liu YX, Huang X, Ren P. Antiapoptotic mechanisms of Chinese medicine formula, Guan-Xin-Er-Hao, in the rat ischemic heart. Tohoku J Exp Med 2008;216:309-316.
31. Wei H, Yang L, Li Q, Li L. Efects of Guanxin II formula on myocardial apoptosis of acute myocardial ischemia in rats. Pharmacol Clin Chin Mater Med (Chin) 2008;24:1-4.
32. Qin F, Liu YX, Zhao HW, Huang X, Ren P, Zhu ZY. Chinese medicinal formula Guan-Xin-Er-Hao protects the heart against oxidative stress induced by acute ischemic myocardial injury in rats. Phytomedicine 2009;16:215-221.
33. Wei H, Yang L, Li L. Effect of Guanxin II on myocardial pathological injury and myocardial enzymes in acute myocardial infarction rats. Lishizhen Med Mater Med Res (Chin) 2008;19:1552-1553.
34. Wang ZY, Qian RQ, Guan SH, Feng XZ, Guo DA, Yan JJ, et al. Study on free radical mechanism of Guanxin II in antagonizing ischemic myocardial damage. Chin J Integr Tradit West Med (Chin) 2003;23:363-366.
35. Su Y, Li Y, Li P, Li L. Effects of blood serum of different officinal forms of Guanxin II formula on ischemia-reperfusion injury in cultured rat myocardial cells. Pharmacol Clin Chin Mater Med (Chin) 2007;23(3):1-4.
36. Gao H, Li Y, Li L. Comparative study on the protective effects of different Guanxin II formula on acute myocardial ischemia in dogs. Pharmacol Clin Chin Mater Med (Chin) 2007;23(5):1-4.
37. Zhang WX, Bai Y, Yue FZ. Influence of Guanxin II on plasma lysophosphatidic acid level in patients with unstable angina. Shaanxi J Tradit Chin Med (Chin) 2006;27:150-151.
38. Wang Y, Liu J, Weng Z. Effect of Guanxin No. 2 combination herb on hemorheology. Prac Clin J Integr Tradit Chin West Med (Chin) 1997;10:1427-1430.
39. 2 in rats. Chin J Tradit Med Sci Technol 2008;15:20-21.
40. Zeng X, Yang J, Yang X, Hong D, Wu L, Yu J. Effect of Guanxin No. 2 Decoction on gene expression in different areas of the myocardial infarcted heart of rats using microarray technology. J Pharm Pharmacol 2009;61:213-219.
41. Yu CY, Liu Z, Xu XM, Li YK, Li LD. Effects of Guanxin II on crdiac protein expression after acute myocardial ischemia on rats. China J Chin Mater Med (Chin) 2008;33:1605-1609.
42. Yu CY, Gao HL, Liu Z, Xu XM, Li YQ, Li LD. Effect of Guanxin No. 2 on gene variant expression profile in rats after myocardial ischemia. Chin J Integr Tradit West Med (Chin) 2008;28:426-430.
43. Tune JD, Gorman MW, Feigl EO. Matching coronary blood flow to myocardial oxygen consumption. J Appl Physiol 2004;97:404-415.
44. Razavi HM, Hamilton JA, Feng Q. Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure. Pharmacol Ther 2005;106:147-162. (Pubitemid 40613056)
45. Kehrer JP. Cause-effect of oxidative stress and apoptosis. Teratology 2000;62:235-236.
46. Wattanapitayakul SK, Bauer JA. Oxidative pathways in cardiovascular disease: roles, mechanisms, and therapeutic implications. Pharmacol Ther 2001;89:187-206. (Pubitemid 32333040)
47. Angiolillo DJ, Guzman LA, Bass TA. Current antiplatelet therapies: benefits and limitations. Am Heart J 2008;156:S3-S9
48. Haensel A, Mills PJ, Nelesen RA. The relationship between heart rate variability and inflammatory markers in cardiovascular diseases. Psychoneuroendocrinology 2008;33:1305-1312.
49. Li LD, Liu JX. The pharmacology studies of Jingzhi-Guanxin. J Trad Chin Med (Chin) 1994;5:32.
50. Chen KJ, Tao SQ, Chen ZJ. The double-blind trial of Jingzhi-Guanxin granula for angina pectoris 112 cases. Chin J Cardiol (Chin) 1982;10:85.
51. Qu SJ. Therapeutic effect of purified Guanxin Soft Capsule in the treatment of angina of coronary heart disease. J Pract Med Tech (Chin) 2007;14:1425-1426.
52. Xu R, Huang X, Li Y, Zhang L, Wang L, Cui P. Clinical observation of treating coronary heart disease with Guanxin-erhao. J Chengdu Univ Tradit Chin Med (Chin) 2001;24:17-19.
53. Zhu AM, Huo P. Treating 42 cases of senile coronary heart disease with Guanxin- II prescription. Hunan Guid J Tradit Chin Med Pharmacol (Chin) 2002;8:63.
54. Wang HJ. Clinical obseveration of Guanxin II for angina pectoris in 122 cases. J Pract Med Tech (Chin) 2006;13:3428-3429.
55. Chen KJ, Qian ZZ, Weng WL. Clinical observation of treating coronary heart disease 100 cases with Huoxue-Chongji. In: Chen KJ, ed. The research of blood stasis syndrome and activating blood to remove blood stasis. Beijing: Peking Medical College & Peking Union Medical College Press; 1993:290.
56. Zhao HL, Liu JL. Clinical observation of treating coronary heart disease with Jiawei Guanxin 2 in 160 cases. J Sichuan Tradit Chin Med (Chin) 2006;24:60.
57. Peng B, Zhao Z. Guanxin II curing coronary heart disease angina pectoris 60 case clinic study. Chin J Pract Chin Modern Med (Chin) 2005;18:948-949.
58. Yang HW, Yang ZQ, Zhao LC. Angina pectoris of coronary heart disease treated by Shengmai-san and Guanxin II in 109 cases. Guangming J Tradit Chin Med (Chin) 2005;20:60-61.
59. Drugs price of Sichuan province. Sichuan Province Medicine Company;2007:23.