메뉴 건너뛰기




Volumn 7, Issue , 2012, Pages 5529-5543

Development and characterization of a novel nanoemulsion drug-delivery system for potential application in oral delivery of protein drugs

Author keywords

Drug delivery system; Nanoemulsion; Oral administration; Protein drug; Stability

Indexed keywords

BOVINE SERUM ALBUMIN; CREMOPHOR; MYRISTIC ACID ISOPROPYL ESTER; PROPYLENE GLYCOL; SODIUM CHLORIDE;

EID: 84870376218     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S36071     Document Type: Article
Times cited : (72)

References (36)
  • 1
    • 33845923234 scopus 로고    scopus 로고
    • High throughput screening of protein formulation stability: Practical considerations
    • Capelle MA, Gurny R, Arvinte T. High throughput screening of protein formulation stability: practical considerations. Eur J Pharm Biopharm. 2007;65(2):131-148.
    • (2007) Eur J Pharm Biopharm , vol.65 , Issue.2 , pp. 131-148
    • Capelle, M.A.1    Gurny, R.2    Arvinte, T.3
  • 3
    • 34547899919 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as a drug delivery system for peptides and proteins
    • Almeida AJ, Souto E. Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv Drug Deliv Rev. 2007;59(6):478-490.
    • (2007) Adv Drug Deliv Rev , vol.59 , Issue.6 , pp. 478-490
    • Almeida, A.J.1    Souto, E.2
  • 4
    • 34250805948 scopus 로고    scopus 로고
    • Polymeric protein delivery systems
    • Lee KY, Yuk SH. Polymeric protein delivery systems. Prog Polym Sci. 2007;32(7):669-697.
    • (2007) Prog Polym Sci , vol.32 , Issue.7 , pp. 669-697
    • Lee, K.Y.1    Yuk, S.H.2
  • 5
    • 14844317382 scopus 로고    scopus 로고
    • Strategic approaches for overcoming peptide and protein instability within biodegradable nano-and microparticles
    • Bilati U, Allémann E, Doelker E. Strategic approaches for overcoming peptide and protein instability within biodegradable nano-and microparticles. Eur J Pharm Biopharm. 2005;59(3):375-388.
    • (2005) Eur J Pharm Biopharm , vol.59 , Issue.3 , pp. 375-388
    • Bilati, U.1    Allémann, E.2    Doelker, E.3
  • 6
    • 45149128290 scopus 로고    scopus 로고
    • Current perspectives on stability of protein drug products during formulation fill and finish operations
    • Rathore N, Rajan RS. Current perspectives on stability of protein drug products during formulation fill and finish operations. Biotechnol Adv. 2008;24(3):504-514.
    • (2008) Biotechnol Adv , vol.24 , Issue.3 , pp. 504-514
    • Rathore, N.1    Rajan, R.S.2
  • 7
    • 0036529145 scopus 로고    scopus 로고
    • Infinite dilution activity coefficients for toluene in aqueous solutions of the protein stabilizers glycerol, ethylene glycol, glucose, sucrose and trehalose
    • Carrillo-Nava E, Dohnal V, Costas M. Infinite dilution activity coefficients for toluene in aqueous solutions of the protein stabilizers glycerol, ethylene glycol, glucose, sucrose and trehalose. J Chem Thermodyn. 2002;34(4):443-456.
    • (2002) J Chem Thermodyn , vol.34 , Issue.4 , pp. 443-456
    • Carrillo-Nava, E.1    Dohnal, V.2    Costas, M.3
  • 8
    • 84870368731 scopus 로고    scopus 로고
    • Helicobacter pylori vaccine delivery systems: Research progress
    • Chinese
    • Sun HW, Liu W, Zou QM. Helicobacter pylori vaccine delivery systems: research progress. J Int Pharm Res. 2009;36(6):431-434. Chinese.
    • (2009) J Int Pharm Res , vol.36 , Issue.6 , pp. 431-434
    • Sun, H.W.1    Liu, W.2    Zou, Q.M.3
  • 9
    • 34447254060 scopus 로고    scopus 로고
    • Preparation, characterization and biodistribution of the lactone form of 10-hydroxycamptothecin (HCPT)-loaded bovine serum albumin (BSA) nanoparticles
    • Yang L, Cui F, Cun D, Tao A, Shi K, Lin W. Preparation, characterization and biodistribution of the lactone form of 10-hydroxycamptothecin (HCPT)-loaded bovine serum albumin (BSA) nanoparticles. Int J Pharm. 2007;340:163-172.
    • (2007) Int J Pharm , vol.340 , pp. 163-172
    • Yang, L.1    Cui, F.2    Cun, D.3    Tao, A.4    Shi, K.5    Lin, W.6
  • 10
    • 64549103787 scopus 로고    scopus 로고
    • Preparation, characterization and in vitro cytotoxicity of BSA-based nanospheres containing nanosized magnetic particles and/or photosensitizer
    • Rodrigues MMA, Simioni AR, Primo FL, Siqueira-Mourab MP, Morais PC, Tedesco AC. Preparation, characterization and in vitro cytotoxicity of BSA-based nanospheres containing nanosized magnetic particles and/or photosensitizer. J Magn Magn Mater. 2009; 32(10):1600-1603.
    • (2009) J Magn Magn Mater , vol.32 , Issue.10 , pp. 1600-1603
    • Rodrigues, M.M.A.1    Simioni, A.R.2    Primo, F.L.3    Siqueira-Mourab, M.P.4    Morais, P.C.5    Tedesco, A.C.6
  • 11
    • 43849090367 scopus 로고    scopus 로고
    • Adsorption of bovin serum albumin (BSA) onto the magnetic chitosan nanoparticles prepared by a microemulsion system
    • Wang Y, Wang X, Luo G, Dai Y. Adsorption of bovin serum albumin (BSA) onto the magnetic chitosan nanoparticles prepared by a microemulsion system. Bioresour Technol. 2008;99(9):3881-3884.
    • (2008) Bioresour Technol , vol.99 , Issue.9 , pp. 3881-3884
    • Wang, Y.1    Wang, X.2    Luo, G.3    Dai, Y.4
  • 12
    • 39649087606 scopus 로고    scopus 로고
    • Preparation and characterization of galactosylated chitosan coated BSA microspheres containing 5-fluorouracil
    • Zhang C, Cheng Y, Qu G, etal. Preparation and characterization of galactosylated chitosan coated BSA microspheres containing 5-fluorouracil. Carbohydr Polym. 2008;72(3):390-397.
    • (2008) Carbohydr Polym , vol.72 , Issue.3 , pp. 390-397
    • Zhang, C.1    Cheng, Y.2    Qu, G.3
  • 13
    • 57649129183 scopus 로고    scopus 로고
    • BSA-FITC-loaded microcapsules for in vivo delivery
    • Kim BS, Oh JM, Kim KS, etal. BSA-FITC-loaded microcapsules for in vivo delivery. Biomaterials. 2009;32(10):902-909.
    • (2009) Biomaterials , vol.32 , Issue.10 , pp. 902-909
    • Kim, B.S.1    Oh, J.M.2    Kim, K.S.3
  • 15
    • 79953685905 scopus 로고    scopus 로고
    • Nanonization strategies for poorly water-soluble drugs
    • Chen H, Khemtong C, Yang X, Chang X, Gao J. Nanonization strategies for poorly water-soluble drugs. Drug Discov Today. 2011;16(7-8): 354-360.
    • (2011) Drug Discov Today , vol.16 , Issue.7-8 , pp. 354-360
    • Chen, H.1    Khemtong, C.2    Yang, X.3    Chang, X.4    Gao, J.5
  • 16
    • 78651379634 scopus 로고    scopus 로고
    • Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: Performance and mechanism
    • Gao F, Zhang Z, Bu H, etal. Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: performance and mechanism. J Control Release. 2011;149(2):168-174.
    • (2011) J Control Release , vol.149 , Issue.2 , pp. 168-174
    • Gao, F.1    Zhang, Z.2    Bu, H.3
  • 17
    • 63649121226 scopus 로고    scopus 로고
    • Enhanced stability of ramipril in nanoemulsion containing cremophor-EL: A technical note
    • Shafiq S, Shakeel F, Khar RK. Enhanced stability of ramipril in nanoemulsion containing cremophor-EL: a technical note. AAPS Pharm Sci Tech. 2008;9(4):1097-1101.
    • (2008) AAPS Pharm Sci Tech , vol.9 , Issue.4 , pp. 1097-1101
    • Shafiq, S.1    Shakeel, F.2    Khar, R.K.3
  • 19
    • 78650284318 scopus 로고    scopus 로고
    • Stability investigation of hyaluronic acid based nanoemulsion and its potential as transdermal carrier
    • Kong M, Park HJ. Stability investigation of hyaluronic acid based nanoemulsion and its potential as transdermal carrier. Carbohydr Polym. 2011;83(3):1303-1310.
    • (2011) Carbohydr Polym , vol.83 , Issue.3 , pp. 1303-1310
    • Kong, M.1    Park, H.J.2
  • 20
    • 78349310679 scopus 로고    scopus 로고
    • Design and investigation of nanoemulsified carrier based on amphiphile-modified hyaluronic acid
    • Kong M, Chen X, Park HJ. Design and investigation of nanoemulsified carrier based on amphiphile-modified hyaluronic acid. Carbohydr Polym. 2011;83(2):462-469.
    • (2011) Carbohydr Polym , vol.83 , Issue.2 , pp. 462-469
    • Kong, M.1    Chen, X.2    Park, H.J.3
  • 21
  • 22
    • 38049016308 scopus 로고    scopus 로고
    • Characterization and stability evaluation of β-carotene nanoemulsions prepared by high pressure homogenization under various emulsifying conditions
    • Yuan Y, Gao Y, Zhao J, Mao L. Characterization and stability evaluation of β-carotene nanoemulsions prepared by high pressure homogenization under various emulsifying conditions. Food Res Int. 2008;41(1):61-68.
    • (2008) Food Res Int , vol.41 , Issue.1 , pp. 61-68
    • Yuan, Y.1    Gao, Y.2    Zhao, J.3    Mao, L.4
  • 23
    • 77957259372 scopus 로고    scopus 로고
    • Nanoemulsions of β-carotene using a high-energy emulsification-evaporation technique
    • Silva HD, Cerqueira MA, Souza BWS, etal. Nanoemulsions of β-carotene using a high-energy emulsification-evaporation technique. J Food Eng. 2011;102:130-135.
    • (2011) J Food Eng , vol.102 , pp. 130-135
    • Silva, H.D.1    Cerqueira, M.A.2    Souza, B.W.S.3
  • 24
    • 77953361632 scopus 로고    scopus 로고
    • Enhancement of stability and skin permeation by sucrose stearate and cyclodextrins in progesterone nanoemulsion
    • Klang V, Matsko N, Zimmermann AM, Vojnikovic E, Valenta C. Enhancement of stability and skin permeation by sucrose stearate and cyclodextrins in progesterone nanoemulsion. Int J Pharm. 2010; 393(1-2):152-160.
    • (2010) Int J Pharm , vol.393 , Issue.1-2 , pp. 152-160
    • Klang, V.1    Matsko, N.2    Zimmermann, A.M.3    Vojnikovic, E.4    Valenta, C.5
  • 25
    • 26444488143 scopus 로고    scopus 로고
    • Enhanced systemic and mucosal immune responses in mice immunized with recombinant Bacillus anthracis protective antigen (rPA) using a novel nanoemulsion adjuvant
    • Baker JR Jr, Bielinska A, Landers J, Janczak K, Cao P. Enhanced systemic and mucosal immune responses in mice immunized with recombinant Bacillus anthracis protective antigen (rPA) using a novel nanoemulsion adjuvant. J Allergy Clin Immunol. 2004;113(2):S292.
    • (2004) J Allergy Clin Immunol , vol.113 , Issue.2
    • Baker Jr., J.R.1    Bielinska, A.2    Landers, J.3    Janczak, K.4    Cao, P.5
  • 26
    • 34548763353 scopus 로고    scopus 로고
    • Design and development of oral in water rampipril nanoemulsion formulation: In vitro and in vivo evaluation
    • Shafiq S, Sushma T, Ahmad FJ. Design and development of oral in water rampipril nanoemulsion formulation: in vitro and in vivo evaluation. J Biomed Nanotechnol. 2007;3:28-44.
    • (2007) J Biomed Nanotechnol , vol.3 , pp. 28-44
    • Shafiq, S.1    Sushma, T.2    Ahmad, F.J.3
  • 27
    • 0037159628 scopus 로고    scopus 로고
    • Size dependent immune response after subcutaneous, oral and intranasal administration of BSA loaded nanospheres
    • Gutierro I, Hernández RM, Igartua M, Gascón AR, Pedraz JL. Size dependent immune response after subcutaneous, oral and intranasal administration of BSA loaded nanospheres. Vaccine. 2002;21(1-2): 67-77.
    • (2002) Vaccine , vol.21 , Issue.1-2 , pp. 67-77
    • Gutierro, I.1    Hernández, R.M.2    Igartua, M.3    Gascón, A.R.4    Pedraz, J.L.5
  • 28
    • 67650995835 scopus 로고    scopus 로고
    • Effects of different oils on the properties of soy protein isolate emulsions and gels
    • Xin Gu, Lydia J, Euston SR. Effects of different oils on the properties of soy protein isolate emulsions and gels. Food Res Int. 2009;42(8): 925-932.
    • (2009) Food Res Int , vol.42 , Issue.8 , pp. 925-932
    • Xin, G.1    Lydia, J.2    Euston, S.R.3
  • 29
    • 75749154095 scopus 로고    scopus 로고
    • Effect of Labrasol on self-nanoemulsification efficiency of ramipril nanoemulsion
    • Shafiq S, Shakeel F. Effect of Labrasol on self-nanoemulsification efficiency of ramipril nanoemulsion. Pharmazie. 2009;64(12): 812-817.
    • (2009) Pharmazie , vol.64 , Issue.12 , pp. 812-817
    • Shafiq, S.1    Shakeel, F.2
  • 30
    • 69449093984 scopus 로고    scopus 로고
    • Investigation of true nanoemulsions for transdermal potential of indomethacin: Characterization, rheological characteristics, and ex vivo skin permeation studies
    • Shakeel F, Ramadan W, Ahmed MA. Investigation of true nanoemulsions for transdermal potential of indomethacin: characterization, rheological characteristics, and ex vivo skin permeation studies. J Drug Target. 2009;17(6):435-441.
    • (2009) J Drug Target , vol.17 , Issue.6 , pp. 435-441
    • Shakeel, F.1    Ramadan, W.2    Ahmed, M.A.3
  • 31
    • 77954256928 scopus 로고    scopus 로고
    • Novel nanoemulsion for minimizing variations in bioavailability of ezetimibe
    • Bali V, Ali M, Ali J. Novel nanoemulsion for minimizing variations in bioavailability of ezetimibe. J Drug Target. 2001;18(7):506-519.
    • (2001) J Drug Target , vol.18 , Issue.7 , pp. 506-519
    • Bali, V.1    Ali, M.2    Ali, J.3
  • 32
    • 38849151208 scopus 로고    scopus 로고
    • Preparation and in vivo evaluation of SMEDDS (self-microemulsifying drug delivery system) containing fenofibrate
    • Patel AR, Vavia PR. Preparation and in vivo evaluation of SMEDDS (self-microemulsifying drug delivery system) containing fenofibrate. AAPS Pharm Sci Tech. 2007;9(3):E344-E352.
    • (2007) AAPS Pharm Sci Tech , vol.9 , Issue.3
    • Patel, A.R.1    Vavia, P.R.2
  • 33
    • 34247205833 scopus 로고    scopus 로고
    • Formulation development and optimization using nanoemulsion technique: A technical note
    • Shafiq-un-Nabi S, Shakeel F, Talegaonkar S, etal. Formulation development and optimization using nanoemulsion technique: a technical note. AAPS Pharm Sci Tech. 2007;8(2):E12-E17.
    • (2007) AAPS Pharm Sci Tech , vol.8 , Issue.2
    • Shafiq-un-Nabi, S.1    Shakeel, F.2    Talegaonkar, S.3
  • 34
    • 34247205833 scopus 로고    scopus 로고
    • Formulation development and optimization using nanoemulsion technique: A technical note
    • Shafiq-un-Nabi S, Shakeel F, Talegaonkar S, etal. Formulation development and optimization using nanoemulsion technique: a technical note. AAPS Pharm Sci Tech. 2007;2(8):28-32.
    • (2007) AAPS Pharm Sci Tech , vol.2 , Issue.8 , pp. 28-32
    • Shafiq-un-Nabi, S.1    Shakeel, F.2    Talegaonkar, S.3
  • 35
    • 0034196519 scopus 로고    scopus 로고
    • Effect of high-pressure homogenization on droplet size distributions and rheological properties of model oil-in-water emulsions
    • Floury J, Desrumaux A, Lardières J. Effect of high-pressure homogenization on droplet size distributions and rheological properties of model oil-in-water emulsions. Innov Food Sci Emerg Technol. 2000; 1(2):127-134.
    • (2000) Innov Food Sci Emerg Technol , vol.1 , Issue.2 , pp. 127-134
    • Floury, J.1    Desrumaux, A.2    Lardières, J.3
  • 36
    • 0032782071 scopus 로고    scopus 로고
    • Instability, stabilization, and formulation of liquid protein pharmaceuticals
    • Wang W. Instability, stabilization, and formulation of liquid protein pharmaceuticals. Int J Pharm. 1999;185(2):129-188.
    • (1999) Int J Pharm , vol.185 , Issue.2 , pp. 129-188
    • Wang, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.