Cell-penetrating superoxide dismutase attenuates oxidative stress-induced senescence by regulating the p53-p21Cip1 pathway and restores osteoblastic differentiation in human dental pulp stem cells

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 5091-5106

  Choi, Yoon Jung ^a   Lee, Jue Yeon ^b   Chung, Chong Pyoung ^b   Park, Yoon Jeong ^a,b  

^a Seoul National University   (South Korea)

^b Research Institute   (South Korea)

Author keywords

Cell penetrating peptide; Dental pulp stem cell; Osteoblastic differentiation; Oxidative stress; Senescence; Superoxide dismutase

Indexed keywords

ANTIOXIDANT; BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; HYDROGEN PEROXIDE; LOW MOLECULAR WEIGHT PROTAMINE SUPEROXIDE DISMUTASE 1 CONJUGATE; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; CELL DIFFERENTIATION; CELL PROTECTION; CELL STRUCTURE; DENTAL PULP STEM CELL; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG PENETRATION; DRUG STRUCTURE; ENZYME ACTIVITY; GENETIC MARKER; GROWTH INHIBITION; HUMAN; HUMAN CELL; OSTEOBLAST; OXIDATIVE STRESS; PROCESS DEVELOPMENT; PROTEIN PROTEIN INTERACTION; SENESCENCE; STEM CELL; TOOTH DEVELOPMENT;

CELL AGING; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DENTAL PULP; HUMANS; OSTEOBLASTS; OSTEOGENESIS; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; STEM CELLS; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84870374939     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S31723     Document Type: Article

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