Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 2325-2337

  Wang, Tiechuang ^a   Yin, Xiaodong ^b   Lu, Yaping ^a   Shan, Weiguang ^a   Xiong, Subin ^a  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b Baxter International Inc   (China)

Author keywords

Emodin; Leukemia; Liposomes; mPEG2000 DSPE; TPGS; Transferrin

Indexed keywords

CHOLESTEROL; DISTEAROYL PHOSPHATIDYLETHANOLAMINE; DRUG CARRIER; EMODIN; LIPOSOME; PHOSPHATIDYLCHOLINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; TOCOFERSOLAN; TRANSFERRIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; B CELL LYMPHOMA; CELL VIABILITY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; DRUG STRUCTURE; ENCAPSULATION; FEMALE; IN VITRO STUDY; LEUKEMIA CELL; LIPOSOMAL DELIVERY; MALE; MOUSE; MYELOID LEUKEMIA; NONHUMAN; PARTICLE SIZE; ULTRASTRUCTURE; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; EMODIN; FEMALE; HUMANS; LEUKEMIA L1210; LIPOSOMES; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED ICR; PARTICLE SIZE; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; RANDOM ALLOCATION; TISSUE DISTRIBUTION; TRANSFERRIN; VITAMIN E;

EID: 84870309736     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S31029     Document Type: Article

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