Prodigiosin activates endoplasmic reticulum stress cell death pathway in human breast carcinoma cell lines

Toxicology and Applied Pharmacology

Volumn 265, Issue 3, 2012, Pages 325-334

  Pan, Mu Yun ^a   Shen, Yuh Chiang ^a,b   Lu, Chien Hsing ^c,d   Yang, Shu Yi ^a   Ho, Tsing Fen ^e   Peng, Yu Ta ^a   Chang, Chia Che ^a,f  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; BCL2; Breast cancer; CHOP GADD153; ER stress; Prodigiosin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PERK PROTEIN; PRODIGIOSIN; PROTEIN; PROTEIN BCL 2; PROTEIN IRE1; THAPSIGARGIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; COLONY FORMATION; CYTOTOXICITY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN CLEAVAGE; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

ACTIVATING TRANSCRIPTION FACTOR 6; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL DEATH; CELL LINE, TUMOR; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; MCF-7 CELLS; PRODIGIOSIN; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TRANSCRIPTION FACTOR CHOP; UNFOLDED PROTEIN RESPONSE; UP-REGULATION;

BACTERIA (MICROORGANISMS);

EID: 84870294008     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.08.034     Document Type: Article

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