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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 24, 2012, Pages 7367-7370

Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B

(5) Van Der Walt, Mietha M a Terre'Blanche, Gisella a Lourens, Anna C U a Petzer, Anél a Petzer, Jacobus P a

a NORTH WEST UNIVERSITY (South Africa)

Author keywords

Benzonitrile; Inhibition; MAO; Monoamine oxidase; Parkinson's disease; Phthalonitrile

Indexed keywords

4 [(4 BROMOBENZYL)SULFANYL]PHTHALONITRILE; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; NITRILE; SULFANYLBENZONITRILE DERIVATIVE; SULFANYLPHTHALONITRILE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; PARKINSON DISEASE; STRUCTURE ACTIVITY RELATION;

DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR CONFORMATION; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; NITRILES; PHTHALIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84870252576 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.10.070 Document Type: Article

Times cited : (10)

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