Folate-mediated delivery of macromolecular anticancer therapeutic agents

Advanced Drug Delivery Reviews

Volumn 64, Issue SUPPL., 2012, Pages 342-352

  Lu, Yingjuan ^a,b   Low, Philip S ^a  

^a PURDUE UNIVERSITY   (United States)

^b Endocyte Inc   (United States)

Author keywords

Folate receptor; Gene therapy vectors; Immunotherapeutic agents; Liposomal therapeutic agents; Macromolecular drug targeting; Prodrug activating enzymes

Indexed keywords

CANCER CELLS; CLASSICAL METHODS; FOLATE RECEPTOR; FOLIC ACIDS; HUMAN CANCER; IN-VITRO; IN-VIVO; LOW MOLECULAR WEIGHT DRUGS; MACROMOLECULAR COMPLEXES; MACROMOLECULAR DRUGS; MACROMOLECULAR THERAPEUTICS; MALIGNANT CELLS; MYELOID CELLS; NORMAL TISSUE; SOLID TUMORS; THERAPEUTIC AGENTS;

DISEASES; DRUG DELIVERY; ORGANIC ACIDS; TUMORS;

MACROMOLECULES;

ANTINEOPLASTIC AGENT; ANTISENSE OLIGODEOXYNUCLEOTIDE; BACTERIAL VACCINE; BOVINE SERUM ALBUMIN; COPOLYMER; DNA; DOXORUBICIN; DRUG CARRIER; DRUG ENCAPSULATING LIPOSOME; ENZYME; FLUORESCEIN ISOTHIOCYANATE; FOLATE CONJUGATED N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; FOLATE POLYETHYLENEGLYCOL CONJUGATED LIPOSOME; FOLATE POLYETHYLENEGLYCOL COPOLYMER; FOLATE POLYETHYLENEGLYCOL DISTEAROYLPHOSPHATIDYLETHANOLAMINE COPOLYMER; FOLATE RECEPTOR; FOLIC ACID; IMMUNOMODULATING AGENT; LIPOSOME; MACROGOL; PENTETATE INDIUM IN 111; POLYLYSINE; PRODRUG; PRODRUG ACTIVATING ENZYME; PROTEIN TOXIN; RIBOSOME INACTIVATING PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TOXIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIRUS VECTOR;

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ANTINEOPLASTIC ACTIVITY; CELL ACTIVATION; CELL MEMBRANE PERMEABILITY; CELL TRANSPORT; DERIVATIZATION; DIFFUSION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG TARGETING; DRUG TRANSPORT; ENCAPSULATION; ENDOCYTOSIS; FOLATE MEDIATED DRUG DELIVERY SYSTEM; GENE THERAPY; GENE VECTOR; HUMAN; IMMUNIZATION; IN VIVO STUDY; LIPOSOMAL DELIVERY; LIPOSOMAL GENE DELIVERY SYSTEM; MACROMOLECULE; MACROPHAGE; MOLECULAR WEIGHT; NEOPLASM; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OVARY CANCER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REVIEW; VIRAL GENE DELIVERY SYSTEM;

EID: 84870244558     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2012.09.020     Document Type: Review

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