The effect of d-amino acid substitution on the selectivity of temporin L towards target cells: Identification of a potent anti-Candida peptide

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 2, 2013, Pages 652-660

  Grieco, Paolo ^a   Carotenuto, Alfonso ^a   Auriemma, Luigia ^a   Saviello, Maria Rosaria ^a   Campiglia, Pietro ^b   Gomez Monterrey, Isabel M ^a   Marcellini, Ludovica ^c   Luca, Vincenzo ^c   Barra, Donatella ^c   Novellino, Ettore ^a   Mangoni, Maria Luisa ^c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Antimicrobial peptide; d Amino acid; Drug resistance; NMR spectroscopy; Peptide membrane interaction; Temporin L

Indexed keywords

[3 PROLINE 11 DEXTRO ARGININE]TEMPORIN L; [3 PROLINE 12 DEXTRO ISOLEUCINE]TEMPORIN L; [3 PROLINE 13 DEXTRO LEUCINE]TEMPORIN L; [3 PROLINE 7 DEXTRO LYSINE]TEMPORIN L; [3 PROLINE 8 DEXTRO PHENYLALANINE]TEMPORIN L; [3 PROLINE 9 DEXTRO LEUCINE]TEMPORIN L; [3 PROLINE]TEMPORIN L; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; TEMPORIN L; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIFUNGAL RESISTANCE; ARTICLE; CANDIDA ALBICANS; CELL VIABILITY; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; HEMOLYSIS; HUMAN; HUMAN CELL; ISOMER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING;

ACINETOBACTER BAUMANNII; AMINO ACID SUBSTITUTION; AMINO ACIDS; CANDIDA; CANDIDA ALBICANS; CIRCULAR DICHROISM; ERYTHROCYTES; ESCHERICHIA COLI; FLUORESCEINS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; YERSINIA PSEUDOTUBERCULOSIS;

ANURA; CANDIDA; MAMMALIA;

EID: 84870202424     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.08.027     Document Type: Article

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