Insight into the modulation of Shaw2 Kv channels by general anesthetics: Structural and functional studies of S4-S5 linker and S6 C-terminal peptides in micelles by NMR

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 2, 2013, Pages 595-601

  Zhang, Jin ^a   Qu, Xiaoguang ^b   Covarrubias, Manuel ^c   Germann, Markus W ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

DOSY; Membrane peptide structure; Micelle; NMR; Potassium channel

Indexed keywords

ALKANOL; BUTANOL; DODECYLPHOSPHORYLCHOLINE; INHALATION ANESTHETIC AGENT; SHAW POTASSIUM CHANNEL; SHAW2 POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BINDING SITE; CHANNEL GATING; CIRCULAR DICHROISM; DROSOPHILA; MICELLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

1-BUTANOL; ANESTHETICS, GENERAL; ANIMALS; BINDING SITES; CELL MEMBRANE; CIRCULAR DICHROISM; DIFFUSION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; IMAGING, THREE-DIMENSIONAL; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; MODELS, STATISTICAL; PEPTIDES; PHOSPHORYLCHOLINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SHAW POTASSIUM CHANNELS; SOLVENTS;

EID: 84870195503     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.09.025     Document Type: Article

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