Solvent-free synthesis, DNA-topoisomerase II activity and molecular docking study of new asymmetrically N,N′-substituted ureas

Molecules

Volumn 17, Issue 11, 2012, Pages 12882-12894

  Andressa, Esteves Souza ^a   Rodrigues Santos, Claudio E ^a   De Nigris Del Cistia, Catarina ^a   Da Silva, Daniel Rosa ^a   Sant'Anna, Carlos Maurício R ^a   Echevarria, Aurea ^a  

^a FEDERAL RURAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

DNA topoisomerase; Molecular docking; Solvent free synthesis; Ureas

Indexed keywords

ALLYL COMPOUND; AMINE; DNA BINDING PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE II ALPHA; DRUG DERIVATIVE; ETOPOSIDE; GYRASE INHIBITOR; ISOCYANIC ACID DERIVATIVE; SCHIFF BASE; TUMOR ANTIGEN; UREA;

ARTICLE; BINDING SITE; CHEMISTRY; GREEN CHEMISTRY; MOLECULAR DOCKING; SYNTHESIS; TRANSITION TEMPERATURE;

ALLYL COMPOUNDS; AMINES; ANTIGENS, NEOPLASM; BINDING SITES; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; ETOPOSIDE; GREEN CHEMISTRY TECHNOLOGY; ISOCYANATES; MOLECULAR DOCKING SIMULATION; SCHIFF BASES; TOPOISOMERASE II INHIBITORS; TRANSITION TEMPERATURE; UREA;

EID: 84870168624     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules171112882     Document Type: Article

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