Gallic acid inhibits gastric cancer cells metastasis and invasive growth via increased expression of RhoB, downregulation of AKT/small GTPase signals and inhibition of NF-κB activity

Toxicology and Applied Pharmacology

Volumn 266, Issue 1, 2013, Pages 76-85

  Ho, Hsieh Hsun ^a   Chang, Chi Sen ^a,b   Ho, Wei Chi ^c   Liao, Sheng You ^a   Lin, Wea Lung ^a,d   Wang, Chau Jong ^a,d  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c JEN AI HOSPITAL   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Gallic acid; Gastric cancer; Metastasis; NF B; RhoB

Indexed keywords

GALLIC ACID; GUANOSINE TRIPHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE B; RHO FACTOR; RHOB PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL GROWTH; CELL INVASION; CONTROLLED STUDY; DRUG EFFICACY; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MALE; METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; STOMACH CARCINOMA; TUMOR CELL; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; DOWN-REGULATION; GALLIC ACID; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP PHOSPHOHYDROLASES; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM INVASIVENESS; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; RHOB GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

ANIMALIA; MUS MUSCULUS;

EID: 84870162513     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.10.019     Document Type: Article

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