메뉴 건너뛰기




Volumn 108, Issue 1, 2013, Pages

Remote ischemic preconditioning regulates HIF-1α levels, apoptosis and inflammation in heart tissue of cardiosurgical patients: A pilot experimental study

Author keywords

Apoptosis; Cardiopulmonary bypass; Inflammation; Remote ischemic preconditioning

Indexed keywords

CASPASE 3; CASPASE 7; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 8; MYELOPEROXIDASE; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA;

EID: 84870055358     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-012-0314-0     Document Type: Article
Times cited : (91)

References (57)
  • 1
    • 34748813173 scopus 로고    scopus 로고
    • Remote ischemic preconditioning reduces myocardial and renal injury after elective abdominal aortic aneurysm repair: A randomized controlled trial
    • DOI 10.1161/circulationaha.106.679167, PII 0000301720070911100014
    • Ali ZA, Callaghan CJ, Lim E, Ali AA, Nouraei SA, Akthar AM, Boyle JR, Varty K, Kharbanda RK, Dutka DP, Gaunt ME (2007) Remote ischemic preconditioning reduces myocardial and renal injury after elective abdominal aortic aneurysm repair: a randomized controlled trial. Circulation 116:I98-I105. doi: 10.1161/circulationaha.106.679167 (Pubitemid 47480776)
    • (2007) Circulation , vol.116 , Issue.11
    • Ali, Z.A.1    Callaghan, C.J.2    Lim, E.3    Ali, A.A.4    Nouraei, S.A.R.5    Akthar, A.M.6    Boyle, J.R.7    Varty, K.8    Kharbanda, R.K.9    Dutka, D.P.10    Gaunt, M.E.11
  • 3
    • 79955484855 scopus 로고    scopus 로고
    • Innate immune signaling in cardiac ischemia
    • 10.1038/nrcardio.2011.38 21448140 10.1038/nrcardio.2011.38 1:CAS:528:DC%2BC3MXltVKjt70%3D
    • Arslan F, de Kleijn DP, Pasterkamp G (2011) Innate immune signaling in cardiac ischemia. Nat Rev Cardiol 8:292-300. doi: 10.1038/nrcardio.2011.38
    • (2011) Nat Rev Cardiol , vol.8 , pp. 292-300
    • Arslan, F.1    De Kleijn, D.P.2    Pasterkamp, G.3
  • 5
    • 38849182762 scopus 로고    scopus 로고
    • Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1α
    • DOI 10.1093/cvr/cvm035
    • Cai Z, Zhong H, Bosch-Marce M, Fox-Talbot K, Wang L, Wei C, Trush MA, Semenza GL (2008) Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha. Cardiovasc Res 77:463-470. doi: 10.1093/cvr/cvm035 (Pubitemid 351197653)
    • (2008) Cardiovascular Research , vol.77 , Issue.3 , pp. 463-470
    • Cai, Z.1    Zhong, H.2    Bosch-Marce, M.3    Fox-Talbot, K.4    Wang, L.5    Wei, C.6    Trush, M.A.7    Semenza, G.L.8
  • 6
    • 32144454172 scopus 로고    scopus 로고
    • Mechanisms of disease: The many roles of chemokines and chemokine receptors in inflammation
    • DOI 10.1056/NEJMra052723
    • Charo IF, Ransohoff RM (2006) The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 354:610-621. doi: 10.1056/NEJMra052723 (Pubitemid 43209108)
    • (2006) New England Journal of Medicine , vol.354 , Issue.6 , pp. 610-621
    • Charo, I.F.1    Ransohoff, R.M.2
  • 7
    • 73649086907 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha induces corticosteroid-insensitive inflammation via reduction of histone deacetylase-2 transcription
    • 10.1074/jbc.M109.025387 19880520 10.1074/jbc.M109.025387 1:CAS:528:DC%2BD1MXhsFyiurzL
    • Charron CE, Chou PC, Coutts DJ, Kumar V, To M, Akashi K, Pinhu L, Griffiths M, Adcock IM, Barnes PJ, Ito K (2009) Hypoxia-inducible factor 1alpha induces corticosteroid-insensitive inflammation via reduction of histone deacetylase-2 transcription. J Biol Chem 284:36047-36054. doi: 10.1074/jbc.M109.025387
    • (2009) J Biol Chem , vol.284 , pp. 36047-36054
    • Charron, C.E.1    Chou, P.C.2    Coutts, D.J.3    Kumar, V.4    To, M.5    Akashi, K.6    Pinhu, L.7    Griffiths, M.8    Adcock, I.M.9    Barnes, P.J.10    Ito, K.11
  • 10
    • 47649128513 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 is central to cardioprotection: A new paradigm for ischemic preconditioning
    • 10.1161/CIRCULATIONAHA.107.758516 18591435 10.1161/CIRCULATIONAHA.107. 758516 1:CAS:528:DC%2BD1cXnvFCgs7o%3D
    • Eckle T, Kohler D, Lehmann R, El Kasmi K, Eltzschig HK (2008) Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning. Circulation 118:166-175. doi: 10.1161/CIRCULATIONAHA. 107.758516
    • (2008) Circulation , vol.118 , pp. 166-175
    • Eckle, T.1    Kohler, D.2    Lehmann, R.3    El Kasmi, K.4    Eltzschig, H.K.5
  • 11
    • 0026647866 scopus 로고
    • Tumor necrosis factor-alpha pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury
    • 10.1016/0006-291X(92)90698-K 1374234 10.1016/0006-291X(92)90698-K 1:CAS:528:DyaK38XisFeku7c%3D
    • Eddy LJ, Goeddel DV, Wong GH (1992) Tumor necrosis factor-alpha pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun 184:1056-1059. doi: 10.1016/0006-291X(92) 90698-K
    • (1992) Biochem Biophys Res Commun , vol.184 , pp. 1056-1059
    • Eddy, L.J.1    Goeddel, D.V.2    Wong, G.H.3
  • 12
    • 79951829343 scopus 로고    scopus 로고
    • Hypoxia and inflammation
    • 10.1056/NEJMra0910283 21323543 10.1056/NEJMra0910283 1:CAS:528: DC%2BC3MXitFykt78%3D
    • Eltzschig HK, Carmeliet P (2011) Hypoxia and inflammation. N Engl J Med 364:656-665. doi: 10.1056/NEJMra0910283
    • (2011) N Engl J Med , vol.364 , pp. 656-665
    • Eltzschig, H.K.1    Carmeliet, P.2
  • 13
    • 77950627242 scopus 로고    scopus 로고
    • IL-1 pathways in inflammation and human diseases
    • 10.1038/nrrheum.2010.4 20177398 10.1038/nrrheum.2010.4 1:CAS:528:DC%2BC3cXktVCqtr0%3D
    • Gabay C, Lamacchia C, Palmer G (2010) IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 6:232-241. doi: 10.1038/nrrheum.2010.4
    • (2010) Nat Rev Rheumatol , vol.6 , pp. 232-241
    • Gabay, C.1    Lamacchia, C.2    Palmer, G.3
  • 14
    • 58849160804 scopus 로고    scopus 로고
    • Neurological complications of cardiac surgery
    • 10.1055/s-0028-1105973 19115176 10.1055/s-0028-1105973
    • Gottesman RF, McKhann GM, Hogue CW (2008) Neurological complications of cardiac surgery. Semin Neurol 28:703-715. doi: 10.1055/s-0028-1105973
    • (2008) Semin Neurol , vol.28 , pp. 703-715
    • Gottesman, R.F.1    McKhann, G.M.2    Hogue, C.W.3
  • 15
    • 47049090546 scopus 로고    scopus 로고
    • Ischemic preconditioning and myocardial infarction: An update and perspective
    • DOI 10.1016/j.ddmec.2007.10.005, PII S174067650700020X
    • Gross ER, Gross GJ (2007) Ischemic preconditioning and myocardial infarction: an update and perspective. Drug Discov Today Dis Mech 4:165-174. doi: 10.1016/j.ddmec.2007.10.005 (Pubitemid 351966334)
    • (2007) Drug Discovery Today: Disease Mechanisms , vol.4 , Issue.3 , pp. 165-174
    • Gross, E.R.1    Gross, G.J.2
  • 16
    • 0033844768 scopus 로고    scopus 로고
    • Does remote organ ischaemia trigger cardiac preconditioning during coronary artery surgery?
    • 10.1006/phrs.1999.0611 10704275 10.1006/phrs.1999.0611 1:STN:280:DC%2BD3c7ntFOltA%3D%3D
    • Gunaydin B, Cakici I, Soncul H, Kalaycioglu S, Cevik C, Sancak B, Kanzik I, Karadenizli Y (2000) Does remote organ ischaemia trigger cardiac preconditioning during coronary artery surgery? Pharmacol Res 41:493-496. doi: 10.1006/phrs.1999.0611
    • (2000) Pharmacol Res , vol.41 , pp. 493-496
    • Gunaydin, B.1    Cakici, I.2    Soncul, H.3    Kalaycioglu, S.4    Cevik, C.5    Sancak, B.6    Kanzik, I.7    Karadenizli, Y.8
  • 17
    • 84860148712 scopus 로고    scopus 로고
    • Cardioprotection during cardiac surgery
    • 10.1093/cvr/cvs131 22440888 10.1093/cvr/cvs131 1:CAS:528: DC%2BC38XmtVegtrk%3D
    • Hausenloy DJ, Boston-Griffiths E, Yellon DM (2012) Cardioprotection during cardiac surgery. Cardiovasc Res 94:253-265. doi: 10.1093/cvr/cvs131
    • (2012) Cardiovasc Res , vol.94 , pp. 253-265
    • Hausenloy, D.J.1    Boston-Griffiths, E.2    Yellon, D.M.3
  • 20
    • 67349145405 scopus 로고    scopus 로고
    • Preconditioning and postconditioning: Underlying mechanisms and clinical application
    • 10.1016/j.atherosclerosis.2008.10.029 19081095 10.1016/j.atherosclerosis. 2008.10.029 1:CAS:528:DC%2BD1MXmtl2lsLc%3D
    • Hausenloy DJ, Yellon DM (2009) Preconditioning and postconditioning: underlying mechanisms and clinical application. Atherosclerosis 204:334-341. doi: 10.1016/j.atherosclerosis.2008.10.029
    • (2009) Atherosclerosis , vol.204 , pp. 334-341
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 21
    • 80055033089 scopus 로고    scopus 로고
    • The therapeutic potential of ischemic conditioning: An update
    • 10.1038/nrcardio.2011.85 10.1038/nrcardio.2011.85
    • Hausenloy DJ, Yellon DM (2010) The therapeutic potential of ischemic conditioning: an update. Nat Rev Cardiol 8:619-629. doi: 10.1038/nrcardio.2011. 85
    • (2010) Nat Rev Cardiol , vol.8 , pp. 619-629
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 22
    • 41149172247 scopus 로고    scopus 로고
    • Remote vs. ischaemic preconditioning: The differential role of mitogen-activated protein kinase pathways
    • DOI 10.1093/cvr/cvm114
    • Heidbreder M, Naumann A, Tempel K, Dominiak P, Dendorfer A (2008) Remote vs. ischaemic preconditioning: the differential role of mitogen-activated protein kinase pathways. Cardiovasc Res 78:108-115. doi: 10.1093/cvr/cvm114 (Pubitemid 351430955)
    • (2008) Cardiovascular Research , vol.78 , Issue.1 , pp. 108-115
    • Heidbreder, M.1    Naumann, A.2    Tempel, K.3    Dominiak, P.4    Dendorfer, A.5
  • 23
    • 84872088738 scopus 로고    scopus 로고
    • Cardioprotection: Chances and challenges of its translation to the clinic
    • 10.1016/S0140-6736(12)60916-7 23095318
    • Heusch G (2012) Cardioprotection: chances and challenges of its translation to the clinic. Lancet. doi: 10.1016/S0140-6736(12)60916-7
    • (2012) Lancet
    • Heusch, G.1
  • 24
    • 84867717542 scopus 로고    scopus 로고
    • HIF-1alpha and paradoxical phenomena in cardioprotection
    • 10.1093/cvr/cvs145 22822099 10.1093/cvr/cvs145 1:CAS:528: DC%2BC38XhsFCqt73N
    • Heusch G (2012) HIF-1alpha and paradoxical phenomena in cardioprotection. Cardiovasc Res 96:214-215. doi: 10.1093/cvr/cvs145
    • (2012) Cardiovasc Res , vol.96 , pp. 214-215
    • Heusch, G.1
  • 25
    • 57149142506 scopus 로고    scopus 로고
    • Cardioprotection: Nitric oxide, protein kinases, and mitochondria
    • 10.1161/CIRCULATIONAHA.108.805242 18981312 10.1161/CIRCULATIONAHA.108. 805242
    • Heusch G, Boengler K, Schulz R (2008) Cardioprotection: nitric oxide, protein kinases, and mitochondria. Circulation 118:1915-1919. doi: 10.1161/CIRCULATIONAHA.108.805242
    • (2008) Circulation , vol.118 , pp. 1915-1919
    • Heusch, G.1    Boengler, K.2    Schulz, R.3
  • 26
    • 84855341208 scopus 로고    scopus 로고
    • STAT5 activation and cardioprotection by remote ischemic preconditioning in humans: Short communication
    • 10.1161/CIRCRESAHA.111.259556 22116817 10.1161/CIRCRESAHA.111.259556 1:CAS:528:DC%2BC38XivFWluw%3D%3D
    • Heusch G, Musiolik J, Kottenberg E, Peters J, Jakob H, Thielmann M (2012) STAT5 activation and cardioprotection by remote ischemic preconditioning in humans: short communication. Circ Res 110:111-115. doi: 10.1161/CIRCRESAHA.111. 259556
    • (2012) Circ Res , vol.110 , pp. 111-115
    • Heusch, G.1    Musiolik, J.2    Kottenberg, E.3    Peters, J.4    Jakob, H.5    Thielmann, M.6
  • 27
  • 28
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • 10.1126/science.1183021 20075244 10.1126/science.1183021 1:CAS:528:DC%2BC3cXktlWkuw%3D%3D
    • Iwasaki A, Medzhitov R (2010) Regulation of adaptive immunity by the innate immune system. Science 327:291-295. doi: 10.1126/science.1183021
    • (2010) Science , vol.327 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 29
    • 0032869566 scopus 로고    scopus 로고
    • The role of neutrophils in myocardial ischemia-reperfusion injury
    • DOI 10.1016/S0008-6363(99)00187-X, PII S000863639900187X
    • Jordan JE, Zhao ZQ, Vinten-Johansen J (1999) The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc Res 43:860-878. doi: 10.1016/S0008-6363(99)00187-X (Pubitemid 29413185)
    • (1999) Cardiovascular Research , vol.43 , Issue.4 , pp. 860-878
    • Jordan, J.E.1    Zhao, Z.-Q.2    Vinten-Johansen, J.3
  • 30
    • 49449108952 scopus 로고    scopus 로고
    • The role of neutrophils and monocytes in innate immunity
    • 10.1159/000136335 18511859 10.1159/000136335 1:CAS:528: DC%2BD1MXltlSnsr8%3D
    • Kantari C, Pederzoli-Ribeil M, Witko-Sarsat V (2008) The role of neutrophils and monocytes in innate immunity. Contrib Microbiol 15:118-146. doi: 10.1159/000136335
    • (2008) Contrib Microbiol , vol.15 , pp. 118-146
    • Kantari, C.1    Pederzoli-Ribeil, M.2    Witko-Sarsat, V.3
  • 31
    • 79959758028 scopus 로고    scopus 로고
    • Remote intermittent ischemia before coronary artery bypass graft surgery: A strategy to reduce injury and inflammation?
    • 10.1007/s00395-011-0185-9 21544683 10.1007/s00395-011-0185-9 1:CAS:528:DC%2BC3MXmvVaitb0%3D
    • Karuppasamy P, Chaubey S, Dew T, Musto R, Sherwood R, Desai J, John L, Shah AM, Marber MS, Kunst G (2011) Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation? Basic Res Cardiol 106:511-519. doi: 10.1007/s00395-011-0185-9
    • (2011) Basic Res Cardiol , vol.106 , pp. 511-519
    • Karuppasamy, P.1    Chaubey, S.2    Dew, T.3    Musto, R.4    Sherwood, R.5    Desai, J.6    John, L.7    Shah, A.M.8    Marber, M.S.9    Kunst, G.10
  • 33
    • 79952115434 scopus 로고    scopus 로고
    • Role of neutrophils in innate immunity: A systems biology-level approach
    • 10.1002/wsbm.32 20836000 10.1002/wsbm.32 1:CAS:528:DC%2BC3cXmtVSrt7s%3D
    • Kobayashi SD, DeLeo FR (2009) Role of neutrophils in innate immunity: a systems biology-level approach. Wiley Interdiscip Rev Syst Biol Med 1:309-333. doi: 10.1002/wsbm.32
    • (2009) Wiley Interdiscip Rev Syst Biol Med , vol.1 , pp. 309-333
    • Kobayashi, S.D.1    Deleo, F.R.2
  • 34
    • 77957204899 scopus 로고    scopus 로고
    • Troponin elevation in heart failure prevalence, mechanisms, and clinical implications
    • 10.1016/j.jacc.2010.06.016 20863950 10.1016/j.jacc.2010.06.016 1:CAS:528:DC%2BC3cXhtlymtrfN
    • Kociol RD, Pang PS, Gheorghiade M, Fonarow GC, O'Connor CM, Felker GM (2010) Troponin elevation in heart failure prevalence, mechanisms, and clinical implications. J Am Coll Cardiol 56:1071-1078. doi: 10.1016/j.jacc.2010.06.016
    • (2010) J Am Coll Cardiol , vol.56 , pp. 1071-1078
    • Kociol, R.D.1    Pang, P.S.2    Gheorghiade, M.3    Fonarow, G.C.4    O'Connor, C.M.5    Felker, G.M.6
  • 35
    • 83555172635 scopus 로고    scopus 로고
    • Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - A clinical trial
    • 10.1111/j.1399-6576.2011.02585.x 22103808 10.1111/j.1399-6576.2011.02585. x 1:CAS:528:DC%2BC38Xht1ahs7Y%3D
    • Kottenberg E, Thielmann M, Bergmann L, Heine T, Jakob H, Heusch G, Peters J (2012) Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial. Acta Anaesthesiol Scand 56:30-38. doi: 10.1111/j.1399-6576.2011.02585.x
    • (2012) Acta Anaesthesiol Scand , vol.56 , pp. 30-38
    • Kottenberg, E.1    Thielmann, M.2    Bergmann, L.3    Heine, T.4    Jakob, H.5    Heusch, G.6    Peters, J.7
  • 36
    • 0027222962 scopus 로고
    • Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia
    • Kuzuya T, Hoshida S, Yamashita N, Fuji H, Oe H, Hori M, Kamada T, Tada M (1993) Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia. Circ Res 72:1293-1299. doi: 10.1161/01.RES.72.6.1293 (Pubitemid 23147612)
    • (1993) Circulation Research , vol.72 , Issue.6 , pp. 1293-1299
    • Kuzuya, T.1    Hoshida, S.2    Yamashita, N.3    Fuji, H.4    Oe, H.5    Hori, M.6    Kamada, T.7    Tada, M.8
  • 37
    • 78951483769 scopus 로고    scopus 로고
    • Conditioning of the heart: From pharmacological interventions to local and remote protection: Possible implications for clinical practice
    • 10.1016/j.ijcard.2010.08.010 20817282 10.1016/j.ijcard.2010.08.010
    • Lavi S, Lavi R (2011) Conditioning of the heart: from pharmacological interventions to local and remote protection: possible implications for clinical practice. Int J Cardiol 146:311-318. doi: 10.1016/j.ijcard.2010.08.010
    • (2011) Int J Cardiol , vol.146 , pp. 311-318
    • Lavi, S.1    Lavi, R.2
  • 38
    • 0035063678 scopus 로고    scopus 로고
    • The role of interleukin-1 in the failing heart
    • DOI 10.1023/A:1011428824771
    • Long CS (2001) The role of interleukin-1 in the failing heart. Heart Fail Rev 6:81-94. doi: 10.1023/A:1011428824771 (Pubitemid 32328171)
    • (2001) Heart Failure Reviews , vol.6 , Issue.2 , pp. 81-94
    • Maan, D.L.1
  • 39
    • 40949088023 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion
    • DOI 10.1038/cdd.2008.13, PII CDD200813, The biology of Hypoxia-inducible factors
    • Loor G, Schumacker PT (2008) Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion. Cell Death Differ 15:686-690. doi: 10.1038/cdd.2008.13 (Pubitemid 351405073)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 686-690
    • Loor, G.1    Schumacker, P.T.2
  • 40
    • 84855790492 scopus 로고    scopus 로고
    • Ischemic preconditioning reduces endoplasmic reticulum stress and upregulates hypoxia inducible factor-1alpha in ischemic kidney: The role of nitric oxide
    • 10.1186/1423-0127-19-7 22252226 10.1186/1423-0127-19-7 1:CAS:528:DC%2BC38Xlt12is7w%3D
    • Mahfoudh-Boussaid A, Zaouali MA, Hadj-Ayed K, Miled AH, Saidane-Mosbahi D, Rosello-Catafau J, Ben Abdennebi H (2012) Ischemic preconditioning reduces endoplasmic reticulum stress and upregulates hypoxia inducible factor-1alpha in ischemic kidney: the role of nitric oxide. J Biomed Sci 19:7. doi: 10.1186/1423-0127-19-7
    • (2012) J Biomed Sci , vol.19 , pp. 7
    • Mahfoudh-Boussaid, A.1    Zaouali, M.A.2    Hadj-Ayed, K.3    Miled, A.H.4    Saidane-Mosbahi, D.5    Rosello-Catafau, J.6    Ben Abdennebi, H.7
  • 42
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
    • Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124-1136. doi: 10.1161/01.CIR.74.5.1124 (Pubitemid 17174962)
    • (1986) Circulation , vol.74 , Issue.5 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 44
    • 80051534224 scopus 로고    scopus 로고
    • Remote ischemic preconditioning: Current knowledge, unresolved questions, and future priorities
    • 10.1177/1074248411409040 21821525 10.1177/1074248411409040
    • Przyklenk K, Whittaker P (2011) Remote ischemic preconditioning: current knowledge, unresolved questions, and future priorities. J Cardiovasc Pharmacol Ther 16:255-259. doi: 10.1177/1074248411409040
    • (2011) J Cardiovasc Pharmacol Ther , vol.16 , pp. 255-259
    • Przyklenk, K.1    Whittaker, P.2
  • 45
    • 29244470323 scopus 로고    scopus 로고
    • Modulation of systemic inflammatory response after cardiac surgery
    • Raja SG, Dreyfus GD (2005) Modulation of systemic inflammatory response after cardiac surgery. Asian Cardiovasc Thorac Ann 13:382-395 (Pubitemid 41824742)
    • (2005) Asian Cardiovascular and Thoracic Annals , vol.13 , Issue.4 , pp. 382-395
    • Raja, S.G.1    Dreyfus, G.D.2
  • 46
    • 33745957572 scopus 로고    scopus 로고
    • Proapoptotic multidomain Bcl-2/Bax-family proteins: Mechanisms, physiological roles, and therapeutic opportunities
    • DOI 10.1038/sj.cdd.4401975, PII 4401975
    • Reed JC (2006) Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities. Cell Death Differ 13:1378-1386. doi: 10.1038/sj.cdd.4401975 (Pubitemid 44057473)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.8 , pp. 1378-1386
    • Reed, J.C.1
  • 47
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • DOI 10.1038/nrm1496
    • Riedl SJ, Shi Y (2004) Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 5:897-907. doi: 10.1038/nrm1496 (Pubitemid 39486541)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.11 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 48
    • 70649095109 scopus 로고    scopus 로고
    • Signaling pathways of cardioprotective ischemic preconditioning
    • 10.1016/j.ijsu.2009.06.004 19540944 10.1016/j.ijsu.2009.06.004
    • Sadat U (2009) Signaling pathways of cardioprotective ischemic preconditioning. Int J Surg 7:490-498. doi: 10.1016/j.ijsu.2009.06.004
    • (2009) Int J Surg , vol.7 , pp. 490-498
    • Sadat, U.1
  • 49
    • 35148828429 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 (HIF-1) pathway
    • doi: 10.1126/stke.4072007cm8
    • Semenza GL (2007) Hypoxia-inducible factor 1 (HIF-1) pathway. Sci STKE 2007:cm8 doi: 10.1126/stke.4072007cm8
    • (2007) Sci STKE 2007
    • Semenza, G.L.1
  • 50
    • 79957952535 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
    • 10.1016/j.bbamcr.2010.08.006 20732359 10.1016/j.bbamcr.2010.08.006 1:CAS:528:DC%2BC3MXntV2ls7c%3D
    • Semenza GL (2011) Hypoxia-inducible factor 1: regulator of mitochondrial metabolism and mediator of ischemic preconditioning. Biochim Biophys Acta 1813:1263-1268. doi: 10.1016/j.bbamcr.2010.08.006
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 1263-1268
    • Semenza, G.L.1
  • 51
    • 67649612042 scopus 로고    scopus 로고
    • Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: Evidence suggesting cross-species protection
    • 10.1042/CS20080523 10.1042/CS20080523 1:CAS:528:DC%2BD1MXpt1KitLo%3D
    • Shimizu M, Tropak M, Diaz RJ, Suto F, Surendra H, Kuzmin E, Li J, Gross G, Wilson GJ, Callahan J, Redington AN (2009) Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection. Clin Sci (Lond) 117:191-200. doi: 10.1042/CS20080523
    • (2009) Clin Sci (Lond) , vol.117 , pp. 191-200
    • Shimizu, M.1    Tropak, M.2    Diaz, R.J.3    Suto, F.4    Surendra, H.5    Kuzmin, E.6    Li, J.7    Gross, G.8    Wilson, G.J.9    Callahan, J.10    Redington, A.N.11
  • 52
    • 37849014061 scopus 로고    scopus 로고
    • Inflammatory response and cardioprotection during open-heart surgery: The importance of anaesthetics
    • 10.1038/sj.bjp0707526 17952108 10.1038/sj.bjp.0707526 1:CAS:528:DC%2BD1cXisVShtQ%3D%3D
    • Suleiman MS, Zacharowski K, Angelini GD (2008) Inflammatory response and cardioprotection during open-heart surgery: the importance of anaesthetics. Br J Pharmacol 153:21-33. doi: 10.1038/sj.bjp0707526
    • (2008) Br J Pharmacol , vol.153 , pp. 21-33
    • Suleiman, M.S.1    Zacharowski, K.2    Angelini, G.D.3
  • 53
    • 77956190657 scopus 로고    scopus 로고
    • Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrest
    • 10.1007/s00395-010-0104-5 20495811 10.1007/s00395-010-0104-5 1:CAS:528:DC%2BC3cXpslClsro%3D
    • Thielmann M, Kottenberg E, Boengler K, Raffelsieper C, Neuhaeuser M, Peters J, Jakob H, Heusch G (2010) Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrest. Basic Res Cardiol 105:657-664. doi: 10.1007/s00395-010- 0104-5
    • (2010) Basic Res Cardiol , vol.105 , pp. 657-664
    • Thielmann, M.1    Kottenberg, E.2    Boengler, K.3    Raffelsieper, C.4    Neuhaeuser, M.5    Peters, J.6    Jakob, H.7    Heusch, G.8
  • 54
    • 73449143528 scopus 로고    scopus 로고
    • Myeloperoxidase: Molecular mechanisms of action and their relevance to human health and disease
    • 10.1089/ars.2009.2538 19622015 10.1089/ars.2009.2538
    • van der Veen BS, de Winther MP, Heeringa P (2009) Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease. Antioxid Redox Signal 11:2899-2937. doi: 10.1089/ars.2009.2538
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2899-2937
    • Van Der Veen, B.S.1    De Winther, M.P.2    Heeringa, P.3
  • 55
    • 77954520762 scopus 로고    scopus 로고
    • Far from the heart: Receptor cross-talk in remote conditioning
    • 10.1038/nm0710-760 20613755 10.1038/nm0710-760 1:CAS:528: DC%2BC3cXosVKhtrk%3D
    • Weber C (2010) Far from the heart: receptor cross-talk in remote conditioning. Nat Med 16:760-762. doi: 10.1038/nm0710-760
    • (2010) Nat Med , vol.16 , pp. 760-762
    • Weber, C.1
  • 56
    • 0036023636 scopus 로고    scopus 로고
    • Remote preconditioning protects the heart by activating myocardial PKCε-isoform
    • DOI 10.1016/S0008-6363(02)00408-X, PII S000863630200408X
    • Wolfrum S, Schneider K, Heidbreder M, Nienstedt J, Dominiak P, Dendorfer A (2002) Remote preconditioning protects the heart by activating myocardial PKCepsilon-isoform. Cardiovasc Res 55:583-589. doi: 10.1016/S0008-6363(02)00408- X (Pubitemid 34874954)
    • (2002) Cardiovascular Research , vol.55 , Issue.3 , pp. 583-589
    • Wolfrum, S.1    Schneider, K.2    Heidbreder, M.3    Nienstedt, J.4    Dominiak, P.5    Dendorfer, A.6
  • 57
    • 84862777907 scopus 로고    scopus 로고
    • A pilot study investigating the effects of remote ischemic preconditioning in high-risk cardiac surgery using a randomised controlled double-blind protocol
    • 10.1007/s00395-012-0256-6 10.1007/s00395-012-0256-6
    • Young PJ, Dalley P, Garden A, Horrocks C, La Flamme A, Mahon B, Miller J, Pilcher J, Weatherall M, Williams J, Young W, Beasley R (2012) A pilot study investigating the effects of remote ischemic preconditioning in high-risk cardiac surgery using a randomised controlled double-blind protocol. Basic Res Cardiol 107:1-10. doi: 10.1007/s00395-012-0256-6
    • (2012) Basic Res Cardiol , vol.107 , pp. 1-10
    • Young, P.J.1    Dalley, P.2    Garden, A.3    Horrocks, C.4    La Flamme, A.5    Mahon, B.6    Miller, J.7    Pilcher, J.8    Weatherall, M.9    Williams, J.10    Young, W.11    Beasley, R.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.