Enhanced in vitro biological activity of synthetic 2-(2-pyridyl) ethyl isothiocyanate compared to natural 4-(methylsulfinyl) butyl isothiocyanate

Journal of Medicinal Chemistry

Volumn 55, Issue 22, 2012, Pages 9682-9692

  Melchini, Antonietta ^a   Needs, Paul W ^a   Mithen, Richard F ^a   Traka, Maria H ^a  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 PYRIDYL)ETHYL ISOTHIOCYANATE; ISOTHIOCYANIC ACID DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P21; SULFORAPHANE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MALE; SIGNAL TRANSDUCTION;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BRASSICA; CELL PROLIFERATION; COLONIC NEOPLASMS; DIET; GENE EXPRESSION PROFILING; HUMANS; ISOTHIOCYANATES; LIVER NEOPLASMS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; THIOCYANATES; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 84870052576     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300929v     Document Type: Article

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