-
1
-
-
0029558313
-
Chemoprotection against cancer by Phase 2 enzyme induction
-
DOI 10.1016/0378-4274(95)03553-2
-
P. Talalay, J.W. Fahey, W.D. Holtzclaw, T. Prestera, and Y. Zhang Chemoprotection against cancer by phase 2 enzyme induction Toxicol. Lett. 82-83 1995 173 179 (Pubitemid 26057505)
-
(1995)
Toxicology Letters
, vol.82-83
, pp. 173-179
-
-
Talalay, P.1
Fahey, J.W.2
Holtzclaw, W.D.3
Prestera, T.4
Zhang, Y.5
-
2
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
DOI 10.1128/MCB.24.24.10941-10953.2004
-
D.D. Zhang, S.C. Lo, J.V. Cross, D.J. Templeton, and M. Hannink Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex Mol. Cell. Biol. 24 2004 10941 10953 (Pubitemid 39603148)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.-C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
3
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
K. Itoh, N. Wakabayashi, Y. Katoh, T. Ishii, K. Igarashi, J.D. Engel, and M. Yamamoto Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain Genes Dev. 13 1999 76 86 (Pubitemid 29045117)
-
(1999)
Genes and Development
, vol.13
, Issue.1
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
5
-
-
3042559902
-
Xanthohumol and related prenylflavonoids from hops and beer: To your good health!
-
DOI 10.1016/j.phytochem.2004.04.025, PII S0031942204001876
-
J.F. Stevens, and J.E. Page Xanthohumol and related prenylflavonoids from hops and beer: to your good health! Phytochemistry 65 2004 1317 1330 (Pubitemid 38844716)
-
(2004)
Phytochemistry
, vol.65
, Issue.10
, pp. 1317-1330
-
-
Stevens, J.F.1
Page, J.E.2
-
6
-
-
33746238114
-
2 histamine receptor signaling
-
DOI 10.1124/mol.106.023226
-
D.C. Kim, S.Y. Choi, S.H. Kim, B.S. Yun, I.D. Yoo, N.R. Reddy, H.S. Yoon, and K.T. Kim Isoliquiritigenin selectively inhibits H(2) histamine receptor signaling Mol. Pharmacol. 70 2006 493 500 (Pubitemid 44092310)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.2
, pp. 493-500
-
-
Kim, D.-C.1
Choi, S.-Y.2
Kim, S.-H.3
Yun, B.-S.4
Yoo, I.-D.5
Reddy, N.R.P.6
Ho, S.Y.7
Kim, K.-T.8
-
7
-
-
34247282872
-
Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin
-
DOI 10.1016/j.freeradbiomed.2007.02.017, PII S0891584907001487
-
S. Tanigawa, M. Fujii, and D.X. Hou Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin Free Radic. Biol. Med. 42 2007 1690 1703 (Pubitemid 46617147)
-
(2007)
Free Radical Biology and Medicine
, vol.42
, Issue.11
, pp. 1690-1703
-
-
Tanigawa, S.1
Fujii, M.2
Hou, D.-X.3
-
8
-
-
0344915418
-
Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis
-
P. Talalay, M.J. De Long, and H.J. Prochaska Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis Proc. Natl. Acad. Sci. USA 85 1988 8261 8265
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8261-8265
-
-
Talalay, P.1
De Long, M.J.2
Prochaska, H.J.3
-
9
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
DOI 10.1073/pnas.172398899
-
A.T. Dinkova-Kostova, W.D. Holtzclaw, R.N. Cole, K. Itoh, N. Wakabayashi, Y. Katoh, M. Yamamoto, and P. Talalay Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Proc. Natl. Acad. Sci. USA 99 2002 11908 11913 (Pubitemid 34994497)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.18
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
10
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers
-
DOI 10.1073/pnas.0307301101
-
N. Wakabayashi, A.T. Dinkova-Kostova, W.D. Holtzclaw, M.I. Kang, A. Kobayashi, M. Yamamoto, T.W. Kensler, and P. Talalay Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers Proc. Natl. Acad. Sci. USA 101 2004 2040 2045 (Pubitemid 38229011)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.7
, pp. 2040-2045
-
-
Wakabayashi, N.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
Kang, M.-I.4
Kobayashi, A.5
Yamamoto, M.6
Kensler, T.W.7
Talalay, P.8
-
11
-
-
0242580049
-
Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress
-
DOI 10.1128/MCB.23.22.8137-8151.2003
-
D.D. Zhang, and M. Hannink Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress Mol. Cell. Biol. 23 2003 8137 8151 (Pubitemid 37377505)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.22
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
12
-
-
68749091158
-
Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1
-
A.L. Eggler, E. Small, M. Hannink, and A.D. Mesecar Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1 Biochem. J. 422 2009 171 180
-
(2009)
Biochem. J.
, vol.422
, pp. 171-180
-
-
Eggler, A.L.1
Small, E.2
Hannink, M.3
Mesecar, A.D.4
-
13
-
-
58249117780
-
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds
-
M. Kobayashi, L. Li, N. Iwamoto, Y. Nakajima-Takagi, H. Kaneko, Y. Nakayama, M. Eguchi, Y. Wada, Y. Kumagai, and M. Yamamoto The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds Mol. Cell. Biol. 29 2009 493 502
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 493-502
-
-
Kobayashi, M.1
Li, L.2
Iwamoto, N.3
Nakajima-Takagi, Y.4
Kaneko, H.5
Nakayama, Y.6
Eguchi, M.7
Wada, Y.8
Kumagai, Y.9
Yamamoto, M.10
-
14
-
-
26444562318
-
Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1
-
DOI 10.1021/ac050892r
-
G. Liu, A.L. Eggler, B.M. Dietz, A.D. Mesecar, J.L. Bolton, J.M. Pezzuto, and R.B. van Breemen Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1 Anal. Chem. 77 2005 6407 6414 (Pubitemid 41436981)
-
(2005)
Analytical Chemistry
, vol.77
, Issue.19
, pp. 6407-6414
-
-
Liu, G.1
Eggler, A.L.2
Dietz, B.M.3
Mesecar, A.D.4
Bolton, J.L.5
Pezzuto, J.M.6
Van Breemen, R.B.7
-
15
-
-
22544464124
-
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
-
DOI 10.1073/pnas.0502402102
-
A.L. Eggler, G. Liu, J.M. Pezzuto, R.B. van Breemen, and A.D. Mesecar Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2 Proc. Natl. Acad. Sci. USA 102 2005 10070 10075 (Pubitemid 41023327)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.29
, pp. 10070-10075
-
-
Eggler, A.L.1
Liu, G.2
Pezzuto, J.M.3
Van Breemen, R.B.4
Mesecar, A.D.5
-
16
-
-
63349104334
-
Detection and quantification of protein adduction by electrophilic fatty acids: Mitochondrial generation of fatty acid nitroalkene derivatives
-
F.J. Schopfer, C. Batthyany, P.R. Baker, G. Bonacci, M.P. Cole, V. Rudolph, A.L. Groeger, T.K. Rudolph, S. Nadtochiy, P.S. Brookes, and B.A. Freeman Detection and quantification of protein adduction by electrophilic fatty acids: mitochondrial generation of fatty acid nitroalkene derivatives Free Radic. Biol. Med. 46 2009 1250 1259
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 1250-1259
-
-
Schopfer, F.J.1
Batthyany, C.2
Baker, P.R.3
Bonacci, G.4
Cole, M.P.5
Rudolph, V.6
Groeger, A.L.7
Rudolph, T.K.8
Nadtochiy, S.9
Brookes, P.S.10
Freeman, B.A.11
-
18
-
-
33645993864
-
Quinone reductase induction as a biomarker for cancer chemoprevention
-
M. Cuendet, C.P. Oteham, R.C. Moon, and J.M. Pezzuto Quinone reductase induction as a biomarker for cancer chemoprevention J. Nat. Prod. 69 2006 460 463
-
(2006)
J. Nat. Prod.
, vol.69
, pp. 460-463
-
-
Cuendet, M.1
Oteham, C.P.2
Moon, R.C.3
Pezzuto, J.M.4
-
19
-
-
36349020163
-
Sites of Alkylation of Human Keap1 by Natural Chemoprevention Agents
-
DOI 10.1016/j.jasms.2007.09.015, PII S1044030507008483
-
Y. Luo, A.L. Eggler, D. Liu, G. Liu, A.D. Mesecar, and R.B. van Breemen Sites of alkylation of human Keap1 by natural chemoprevention agents J. Am. Soc. Mass Spectrom. 18 2007 2226 2232 (Pubitemid 350161332)
-
(2007)
Journal of the American Society for Mass Spectrometry
, vol.18
, Issue.12
, pp. 2226-2232
-
-
Luo, Y.1
Eggler, A.L.2
Liu, D.3
Liu, G.4
Mesecar, A.D.5
Van Breemen, R.B.6
-
20
-
-
73349102177
-
Transduction of redox signaling by electrophile-protein reactions
-
T.K. Rudolph, and B.A. Freeman Transduction of redox signaling by electrophile-protein reactions Sci. Signal. 2 2009 re7
-
(2009)
Sci. Signal.
, vol.2
, pp. 7
-
-
Rudolph, T.K.1
Freeman, B.A.2
-
21
-
-
0028203252
-
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
-
Y. Zhang, T.W. Kensler, C.G. Cho, G.H. Posner, and P. Talalay Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates Proc. Natl. Acad. Sci. USA 91 1994 3147 3150 (Pubitemid 24130192)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.8
, pp. 3147-3150
-
-
Zhang, Y.1
Kensler, T.W.2
Cho, C.-G.3
Posner, G.H.4
Talalay, P.5
-
22
-
-
34247473917
-
Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts
-
DOI 10.1158/1055-9965.EPI-06-0934
-
A.T. Dinkova-Kostova, J.W. Fahey, K.L. Wade, S.N. Jenkins, T.A. Shapiro, E.J. Fuchs, M.L. Kerns, and P. Talalay Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts Cancer Epidemiol. Biomarkers Prev. 16 2007 847 851 (Pubitemid 46650594)
-
(2007)
Cancer Epidemiology Biomarkers and Prevention
, vol.16
, Issue.4
, pp. 847-851
-
-
Dinkova-Kostova, A.T.1
Fahey, J.W.2
Wade, K.L.3
Jenkins, S.N.4
Shapiro, T.A.5
Fuchs, E.J.6
Kerns, M.L.7
Talalay, P.8
-
24
-
-
74049120454
-
Nrf2: Friend or foe for chemoprevention?
-
T.W. Kensler, and N. Wakabayashi Nrf2: friend or foe for chemoprevention? Carcinogenesis 31 2010 90 99
-
(2010)
Carcinogenesis
, vol.31
, pp. 90-99
-
-
Kensler, T.W.1
Wakabayashi, N.2
-
26
-
-
57349116768
-
Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles
-
H. Liu, A.T. Dinkova-Kostova, and P. Talalay Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles Proc. Natl. Acad. Sci. USA 105 2008 15926 15931
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15926-15931
-
-
Liu, H.1
Dinkova-Kostova, A.T.2
Talalay, P.3
|