-
1
-
-
33646139174
-
Hepatocellular carcinoma as a complex polygenic disease. Interpretative analysis of recent developments on genetic predisposition
-
F. Feo, M.R. De Miglio, M.M. Simile, M.R. Muroni, D.F. Calvisi, M. Frau et al., Hepatocellular carcinoma as a complex polygenic disease. Interpretative analysis of recent developments on genetic predisposition. Biochim. Biophys. Acta Canc. Rev. 1765, 126-147 (2006)
-
(2006)
Biochim. Biophys. Acta Canc. Rev
, vol.1765
, pp. 126-147
-
-
Feo, F.1
De Miglio, M.R.2
Simile, M.M.3
Muroni, M.R.4
Calvisi, D.F.5
Frau, M.6
-
2
-
-
0017692938
-
Rapid emergence of carcinogeninduced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis
-
D.B. Solt, A. Medline, E. Farber, Rapid emergence of carcinogeninduced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis. Am. J. Pathol. 88, 595-618 (1997)
-
(1997)
Am. J. Pathol
, vol.88
, pp. 595-618
-
-
Solt, D.B.1
Medline, A.2
Farber, E.3
-
3
-
-
32944469316
-
Role of the modulation of p16ink4a and e2f4 activity by cdc37, hsp90 and crm1 in the phenotypic behavior of preneoplastic and neoplastic liver lesions of rat strains with different genetic predisposition to hepatocarcinogenesis and in human liver cancer
-
R.M. Pascale, M.M. Simile, D.F. Calvisi, M. Frau, M.R. Muroni, M.A. Seddaiu, L. Daino, M.D. Muntoni, M.R. De Miglio, S.S. Thorgeirsson, F. Feo, Role of the modulation of p16INK4A and E2f4 activity by Cdc37, Hsp90 and Crm1 in the phenotypic behavior of preneoplastic and neoplastic liver lesions of rat strains with different genetic predisposition to hepatocarcinogenesis and in human liver cancer. Hepatology 42, 1310-1319 (2005)
-
(2005)
Hepatology
, vol.42
, pp. 1310-1319
-
-
Pascale, R.M.1
Simile, M.M.2
Calvisi, D.F.3
Frau, M.4
Muroni, M.R.5
Seddaiu, M.A.6
Daino, L.7
Muntoni, M.D.8
De Miglio, M.R.9
Thorgeirsson, S.S.10
Feo, F.11
-
4
-
-
79958841791
-
Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype
-
M. Frau, S. Ladu, D.F. Calvisi, M.M. Simile, P. Bonelli, L. Daino, M.L. Tomasi, M.A. Seddaiu, F. Feo, R.M. Pascale, Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype. J. Hepatol. 55, 111-119 (2011)
-
(2011)
J. Hepatol
, vol.55
, pp. 111-119
-
-
Frau, M.1
Ladu, S.2
Calvisi, D.F.3
Simile, M.M.4
Bonelli, P.5
Daino, L.6
Tomasi, M.L.7
Seddaiu, M.A.8
Feo, F.9
Pascale, R.M.10
-
5
-
-
77951429707
-
Prognostic markers and putative therapeutic targets for hepatocellular carcinoma
-
M. Frau, F. Biasi, F. Feo, R.M. Pascale, Prognostic markers and putative therapeutic targets for hepatocellular carcinoma. Mol. Aspects Med. 31, 179-193 (2010)
-
(2010)
Mol. Aspects Med
, vol.31
, pp. 179-193
-
-
Frau, M.1
Biasi, F.2
Feo, F.3
Pascale, R.M.4
-
6
-
-
79953737159
-
Activation ofmybl2-lin9 complex contributes to human hepatocarcinogenesis and identifies a subset of hcc with mutant p53
-
D.F. Calvisi, M.M. Simile, S. Ladu, M. Frau, M. Evert, M.L. Tomasi, M.I. Demartis, L. Daino, M.A. Seddaiu, S. Brozzetti, F. Feo, R.M. Pascale, Activation ofMYBL2-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of HCC with mutant p53. Hepatology 53, 1226-1236 (2011)
-
(2011)
Hepatology
, vol.53
, pp. 1226-1236
-
-
Calvisi, D.F.1
Simile, M.M.2
Ladu, S.3
Frau, M.4
Evert, M.5
Tomasi, M.L.6
Demartis, M.I.7
Daino, L.8
Seddaiu, M.A.9
Brozzetti, S.10
Feo, F.11
Pascale, R.M.12
-
7
-
-
33745577640
-
Comparative and integrative functional genomics of hcc
-
J.S. Lee, S.S. Thorgeirsson, Comparative and integrative functional genomics of HCC. Oncogene 25, 3089-3801 (2006)
-
(2006)
Oncogene
, vol.25
, pp. 3089-3801
-
-
Lee, J.S.1
Thorgeirsson, S.S.2
-
9
-
-
0034601455
-
Molecular classification of cutaneous malignant melanoma by gene expression profiling
-
DOI 10.1038/35020115
-
M. Bittner, P. Meltzer, Y. Chen, Y. Jiang, E. Seftor, M. Hendrix, M. Radmacher, R. Simon, Z. Yakhini, A. Ben-Dor, N. Sampas, E. Dougherty, E. Wang, F. Marincola, C. Gooden, J. Lueders, A. Glatfelter, P. Pollock, J. Carpten, E. Gillanders, D. Leja, K. Dietrich, C. Beaudry, M. Berens, D. Alberts, V. Sondak, Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature 406, 536-540 (2000) (Pubitemid 30625740)
-
(2000)
Nature
, vol.406
, Issue.6795
, pp. 536-540
-
-
Bittner, M.1
Meltzer, P.2
Chen, Y.3
Jiang, Y.4
Seftor, E.5
Hendrix, M.6
Radmacher, M.7
Simon, R.8
Yakhini, Z.9
Ben-Dor, A.10
Sampas, N.11
Dougherty, E.12
Wang, E.13
Marincola, F.14
Gooden, C.15
Lueders, J.16
Glatfelter, A.17
Pollock, P.18
Carpten, J.19
Gillanders, E.20
Leja, D.21
Dietrich, K.22
Beaudry, C.23
Berens, M.24
Alberts, D.25
Sondak, V.26
Hayward, N.27
Trent, J.28
more..
-
10
-
-
33744788887
-
Gene expression profile related to the progression of preneoplastic nodules toward hepatocellular carcinoma in rats
-
DOI 10.1593/neo.05841
-
J.I. Pérez-Carreón, C. López-García, S. Fattel-Fazenda, E. Arce-Popoca, L. Alemán-Lazarini, S. Hernández-García, V. Le Berre, S. Sokol, J.M. Francois, S. Villa-Treviño, Gene expression profile related to the progression of preneoplastic nodules toward hepatocellular carcinoma in rats. Neoplasia 8, 373-383 (2006) (Pubitemid 43830744)
-
(2006)
Neoplasia
, vol.8
, Issue.5
, pp. 373-383
-
-
Perez-Carreon, J.I.1
Lopez-Garcia, C.2
Fattel-Fazenda, S.3
Arce-Popoca, E.4
Aleman-Lazarini, L.5
Hernandez-Garcia, S.6
Le Berre, V.7
Sokol, S.8
Francois, J.M.9
Villa-Trevino, S.10
-
11
-
-
77950616980
-
Progenitor-derived hepatocellular carcinoma model in the rat
-
J.B. Andersen, R. Loi, A. Perra, G.M. Ledda-Columbano, A. Columbano, S.S. Thorgeirsson, Progenitor-derived hepatocellular carcinoma model in the rat. Hepatology 51, 1401-1409 (2010)
-
(2010)
Hepatology
, vol.51
, pp. 1401-1409
-
-
Andersen, J.B.1
Loi, R.2
Perra, A.3
Ledda-Columbano, G.M.4
Columbano, A.5
Thorgeirsson, S.S.6
-
12
-
-
0016685925
-
Report of a workshop on classification of specific hepatocellular lesions in rats
-
R.A. Squire, M.H. Levitt, Report of a workshop on classification of specific hepatocellular lesions in rats. Cancer Res. 35, 3214-3223 (1975)
-
(1975)
Cancer Res
, vol.35
, pp. 3214-3223
-
-
Squire, R.A.1
Levitt, M.H.2
-
13
-
-
0029155354
-
Terminology of nodular hepatocellular lesions
-
International Working Party, Terminology of nodular hepatocellular lesions. Hepatology 22, 983-993 (1995)
-
(1995)
Hepatology
, vol.22
, pp. 983-993
-
-
Party, I.W.1
-
14
-
-
58849087179
-
Diagnosis and molecular markers
-
M. Sakamoto, Early HCC: diagnosis and molecular markers. J. Gastroenterol. 44(Suppl XIX), 108-111 (2009)
-
(2009)
J. Gastroenterol
, vol.44
, Issue.SUPPL. XIX
, pp. 108-111
-
-
Sakamoto, M.1
Early, H.C.C.2
-
15
-
-
4544273428
-
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
-
DOI 10.1002/hep.20375
-
J.S. Lee, I.S. Chu, J. Heo, D.F. Calvisi, Z. Sun, T. Roskams, A. Durnez, A.J. Demetris, S.S. Thorgeirsson, Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 40, 667-676 (2004) (Pubitemid 39265589)
-
(2004)
Hepatology
, vol.40
, Issue.3
, pp. 667-676
-
-
Lee, J.-S.1
Chu, I.-S.2
Heo, J.3
Calvisi, D.F.4
Sun, Z.5
Roskams, T.6
Durnez, A.7
Demetris, A.J.8
Thorgeirsson, S.S.9
-
16
-
-
9644254191
-
Application of comparative functional genomics to identify best-fit mouse models to study human cancer
-
DOI 10.1038/ng1481
-
J.S. Lee, I.S. Chu, A. Mikaelyan, D.F. Calvisi, J. Heo, J.K. Reddy, S.S. Thorgeirsson, Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat. Genet. 36, 1306-1311 (2004) (Pubitemid 39577940)
-
(2004)
Nature Genetics
, vol.36
, Issue.12
, pp. 1306-1311
-
-
Lee, J.-S.1
Chu, I.-S.2
Mikaelyan, A.3
Calvisi, D.F.4
Heo, J.5
Reddy, J.K.6
Thorgeirsson, S.S.7
-
17
-
-
0141569009
-
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
-
DOI 10.1016/S1535-6108(03)00197-1
-
K. Ellwood-Yen, T.G. Graeber, J. Wongvipat, M.L. Iruela-Arispe, J. Zhang, R. Matusik, G.V. Thomas, C.L. Sawyers, Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 4, 223-238 (2003) (Pubitemid 37163836)
-
(2003)
Cancer Cell
, vol.4
, Issue.3
, pp. 223-238
-
-
Ellwood-Yen, K.1
Graeber, T.G.2
Wongvipat, J.3
Iruela-Arispe, M.L.4
Zhang, J.5
Matusik, R.6
Thomas, G.V.7
Sawyers, C.L.8
-
18
-
-
11244258643
-
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
-
DOI 10.1038/ng1490
-
A. Sweet-Cordero, S. Mukherjee, A. Subramanian, H. You, J.J. Roix, C. Ladd-Acosta, J. Mesirov, T.R. Golub, T. Jacks, An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis. Nat. Genet. 37, 48-55 (2005) (Pubitemid 40070939)
-
(2005)
Nature Genetics
, vol.37
, Issue.1
, pp. 48-55
-
-
Sweet-Cordero, A.1
Mukherjee, S.2
Subramanian, A.3
You, H.4
Roix, J.J.5
Ladd-Acosta, C.6
Mesirov, J.7
Golub, T.R.8
Jacks, T.9
-
19
-
-
66149152693
-
Central role of c-myc during malignant conversion in human hepatocarcinogenesis
-
P. Kaposi-Novak, L. Libbrecht, H.G. Woo, Y.H. Lee, N.C. Sears, C. Coulouarn, E.A. Conner, V.M. Factor, T. Roskams, S.S. Thorgeirsson, Central role of c-Myc during malignant conversion in human hepatocarcinogenesis. Cancer Res. 69, 2775-2782 (2009)
-
(2009)
Cancer Res
, vol.69
, pp. 2775-2782
-
-
Kaposi-Novak, P.1
Libbrecht, L.2
Woo, H.G.3
Lee, Y.H.4
Sears, N.C.5
Coulouarn, C.6
Conner, E.A.7
Factor, V.M.8
Roskams, T.9
Thorgeirsson, S.S.10
-
20
-
-
33745115859
-
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and breast cancer risk: Eight years on
-
DOI 10.1677/erc.1.01219
-
A.G. Renehan, M. Harvie, A. Howell, Insulin-like growth factor (IGF)-I, IGF binding protein-3, and breast cancer risk: eight years on. Endocr. Relat. Canc. 13, 273-278 (2006) (Pubitemid 43886658)
-
(2006)
Endocrine-Related Cancer
, vol.13
, Issue.2
, pp. 273-278
-
-
Renehan, A.G.1
Harvie, M.2
Howell, A.3
-
21
-
-
34250763945
-
Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry
-
DOI 10.1002/hep.21743
-
P. Bioulac-Sage, S. Rebouissou, C. Thomas, J.F. Blanc, J. Saric, A. Sa Cunha, A. Rullier, G. Cubel, G. Couchy, S. Imbeaud, C. Balabaud, J. Zucman-Rossi, Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry. Hepatology 46, 740-748 (2007) (Pubitemid 47436120)
-
(2007)
Hepatology
, vol.46
, Issue.3
, pp. 740-748
-
-
Bioulac-Sage, P.1
Rebouissou, S.2
Thomas, C.3
Blanc, J.-F.4
Saric, J.5
Cunha, A.S.6
Rullier, A.7
Cubel, G.8
Couchy, G.9
Imbeaud, S.10
Balabaud, C.11
Zucman-Rossi, J.12
-
22
-
-
70350104779
-
Skp2 and cks1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis
-
D.F. Calvisi, S. Ladu, F. Pinna, M. Frau, M.L. Tomasi, M. Sini, M.M. Simile, P. Bonelli, M.R. Muroni, M.A. Seddaiu, D.S. Lim, F. Feo, R.M. Pascale, SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis. Gastroenterology 137, 1816-1826 (2009)
-
(2009)
Gastroenterology
, vol.137
, pp. 1816-1826
-
-
Calvisi, D.F.1
Ladu, S.2
Pinna, F.3
Frau, M.4
Tomasi, M.L.5
Sini, M.6
Simile, M.M.7
Bonelli, P.8
Muroni, M.R.9
Seddaiu, M.A.10
Lim, D.S.11
Feo, F.12
Pascale, R.M.13
-
23
-
-
77953124026
-
Loss of csmd1 expression is associated with high tumour grade and poor survival ininvasive ductal breast carcinoma
-
M. Kamal, A.M. Shaaban, L. Zhang, C. Walker, S. Gray, N. Thakker, C. Toomes, V. Speirs, S.M. Bell, Loss of CSMD1 expression is associated with high tumour grade and poor survival ininvasive ductal breast carcinoma. Breast Canc. Res. Treat. 121, 555-563 (2010)
-
(2010)
Breast Canc. Res. Treat
, vol.121
, pp. 555-563
-
-
Kamal, M.1
Shaaban, A.M.2
Zhang, L.3
Walker, C.4
Gray, S.5
Thakker, N.6
Toomes, C.7
Speirs, V.8
Bell, S.M.9
-
24
-
-
40749139957
-
S-adenosylmethionine in cell growth, apoptosis and liver cancer
-
S.C. Lu, J.M. Mato, S-Adenosylmethionine in cell growth, apoptosis and liver cancer. J. Gastroenterol. Hepatol. 23(Suppl 1), 73-77 (2008)
-
(2008)
J. Gastroenterol. Hepatol
, vol.23
, Issue.SUPPL. 1
, pp. 73-77
-
-
Lu, S.C.1
Mato, J.M.2
-
25
-
-
49249093107
-
Dualspecificity phosphatase 1 ubiquitination in extracellular signalregulated kinase-mediated control of growth in human hepatocellular carcinoma
-
D.F. Calvisi, F. Pinna, F. Meloni, S. Ladu, R. Pellegrino, M. Sini, L. Daino, M.M. Simile, M.R. De Miglio, P. Virdis, M. Frau, M.L. Tomasi, M.A. Seddaiu, M.R. Muroni, F. Feo, R.M. Pascale, Dualspecificity phosphatase 1 ubiquitination in extracellular signalregulated kinase-mediated control of growth in human hepatocellular carcinoma. Cancer Res. 68, 4192-4200 (2008)
-
(2008)
Cancer Res
, vol.68
, pp. 4192-4200
-
-
Calvisi, D.F.1
Pinna, F.2
Meloni, F.3
Ladu, S.4
Pellegrino, R.5
Sini, M.6
Daino, L.7
Simile, M.M.8
De Miglio, M.R.9
Virdis, P.10
Frau, M.11
Tomasi, M.L.12
Seddaiu, M.A.13
Muroni, M.R.14
Feo, F.15
Pascale, R.M.16
-
26
-
-
10744220690
-
Carcinogen Inducibility in Vivo and Down-Regulation of DMBT1 during Breast Carcinogenesis
-
DOI 10.1002/gcc.10309
-
J. Mollenhauer, B. Helmke, D. Medina, G. Bergmann, N. Gassler, H. Müller, S. Lyer, L. Diedrichs, M. Renner, R. Wittig, S. Blaich, U. Hamann, J. Madsen, U. Holmskov, F. Bikker, A. Ligtenberg, A. Carlén, J. Olsson, H.F. Otto, B. O'Malley, A. Poustka, Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes Chrom. Cancer 39, 185-194 (2004) (Pubitemid 38209579)
-
(2004)
Genes Chromosomes and Cancer
, vol.39
, Issue.3
, pp. 185-194
-
-
Mollenhauer, J.1
Helmke, B.2
Medina, D.3
Bergmann, G.4
Gassler, N.5
Muller, H.6
Lyer, S.7
Diedrichs, L.8
Renner, M.9
Wittig, R.10
Blaich, S.11
Hamann, U.12
Madsen, J.13
Holmskov, U.14
Bikker, F.15
Ligtenberg, A.16
Carlen, A.17
Olsson, J.18
Otto, H.F.19
O'Malley, B.20
Poustka, A.21
more..
-
27
-
-
35648962315
-
Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis
-
DOI 10.1002/ijc.22940
-
D.F. Calvisi, M.M. Simile, S. Ladu, R. Pellegrino, V. De Murtas, F. Pinna, M.L. Tomasi, M. Frau, P. Virdis, M.R. De Miglio, M.R. Muroni, R.M. Pascale, F. Feo, Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis. Int. J. Cancer 121, 2410-2420 (2007) (Pubitemid 350022410)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.11
, pp. 2410-2420
-
-
Calvisi, D.F.1
Simile, M.M.2
Ladu, S.3
Pellegrino, R.4
De Murtas, V.5
Pinna, F.6
Tomasi, M.L.7
Frau, M.8
Virdis, P.9
De Miglio, M.R.10
Muroni, M.R.11
Pascale, R.M.12
Feo, F.13
-
28
-
-
70350335151
-
Gadd45-alpha and gadd45-gamma utilize p38 and jnk signaling pathways to induce cell cycle g2/m arrest in hep-g2 hepatoma cells
-
N. Zhu, Y. Shao, L. Xu, L. Yu, L. Sun, Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells. Mol. Biol. Rep. 36, 2075-2085 (2009)
-
(2009)
Mol. Biol. Rep
, vol.36
, pp. 2075-2085
-
-
Zhu, N.1
Shao, Y.2
Xu, L.3
Yu, L.4
Sun, L.5
-
29
-
-
39749140202
-
The aspartic protease napsin a suppresses tumor growth independent of its catalytic activity
-
DOI 10.1038/labinvest.3700718, PII 3700718
-
T. Ueno, G. Elmberger, T.E. Weaver, M. Toi, S. Linder, The aspartic protease napsin A suppresses tumor growth independent of its catalytic activity. Lab. Investig. 88, 256-263 (2008) (Pubitemid 351311283)
-
(2008)
Laboratory Investigation
, vol.88
, Issue.3
, pp. 256-263
-
-
Ueno, T.1
Elmberger, G.2
Weaver, T.E.3
Toi, M.4
Linder, S.5
-
30
-
-
84984586015
-
Genetic characterization of fas-associated phosphatase-1 as a putative tumor suppressor gene on chromosome 4q21.3 in hepatocellular carcinoma
-
S.H. Yeh, D.C.Wu, C.Y. Tsai, T.J. Kuo,W.C. Yu, Y.S. Chang, C.L. Chen, C.F. Chang, D.S. Chen, P.J. Chen, Genetic characterization of fas-associated phosphatase-1 as a putative tumor suppressor gene on chromosome 4q21.3 in hepatocellular carcinoma. Clin. Cancer Res. 12, 1097-1108 (2006)
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 1097-1108
-
-
Yeh, S.H.1
Wu, D.C.2
Tsai, C.Y.3
Kuo, W.C.4
Yu, T.J.5
Chang, Y.S.6
Chen, C.L.7
Chang, C.F.8
Chen, D.S.9
Chen, P.J.10
-
32
-
-
0037308777
-
Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer
-
T.L. Tseng, Y.P. Shih, Y.C. Huang, C.K. Wang, P.H. Chen, J.G. Chang, K.T. Yeh, Y.M. Chen, K.H. Buetow, Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer. Cancer Res. 63, 647-654 (2003) (Pubitemid 36158143)
-
(2003)
Cancer Research
, vol.63
, Issue.3
, pp. 647-654
-
-
Tseng, T.-L.1
Shih, Y.-P.2
Huang, Y.-C.3
Wang, C.-K.4
Chen, P.-H.5
Chang, J.-G.6
Yeh, K.-T.7
Chen, Y.-M.A.8
Buetow, K.H.9
-
33
-
-
34447295401
-
Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk
-
DOI 10.2353/ajpath.2007.060512
-
A.C. Blackburn, L.Z. Hill, A.L. Roberts, J. Wang, D. Aud, J. Jung, T. Nikolcheva, J. Allard, G. Peltz, C.N. Otis, Q.J. Cao, R.S. Ricketts, S.P. Naber, J. Mollenhauer, A. Poustka, D. Malamud, D.J. Jerry, Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk. Am. J. Pathol. 170, 2030-2041 (2007) (Pubitemid 47339276)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.6
, pp. 2030-2041
-
-
Blackburn, A.C.1
Hill, L.Z.2
Roberts, A.L.3
Wang, J.4
Aud, D.5
Jung, J.6
Nikolcheva, T.7
Allard, J.8
Peltz, G.9
Otis, C.N.10
Cao, Q.J.11
Ricketts, R.S.J.12
Naber, S.P.13
Mollenhauer, J.14
Poustka, A.15
Malamud, D.16
Jerry, D.J.17
-
34
-
-
33846318206
-
Overexpression of cyclin D1 is associated with elevated levels of MAP kinases, Akt and Pak1 during diethylnitrosamine-induced progressive liver carcinogenesis
-
DOI 10.1016/j.cellbi.2006.09.005, PII S1065699506001971
-
P. Parekh, K.V. Rao, Overexpression of cyclin D1 is associated with elevated levels of MAP kinases, Akt and Pak1 during diethylnitrosamine-induced progressive liver carcinogenesis. Cell Biol. Int. 31, 35-43 (2007) (Pubitemid 46124028)
-
(2007)
Cell Biology International
, vol.31
, Issue.1
, pp. 35-43
-
-
Parekh, P.1
Rao, K.V.K.2
-
35
-
-
0034961050
-
Roles of Akt/PKB and IKK complex in constitutive induction of NF-kappaB in hepatocellular carcinomas of transforming growth factor alpha/c-myc transgenic mice
-
DOI 10.1053/jhep.2001.25270
-
V. Factor, A.L. Oliver, G.R. Panta, S.S. Thorgeirsson, G.E. Sonenshein, M. Arsura, Roles of Akt/PKB and IKK complex in constitutive induction of NF-kappaB in hepatocellular carcinomas of transforming growth factor alpha/c-myc transgenic mice. Hepatology 34, 32-41 (2001) (Pubitemid 32591480)
-
(2001)
Hepatology
, vol.34
, Issue.1
, pp. 32-41
-
-
Factor, V.1
Oliver, A.L.2
Panta, G.R.3
Thorgeirsson, S.S.4
Sonenshein, G.E.5
Arsura, M.6
-
36
-
-
33847069207
-
Genomics and signaling pathways in hepatocellular carcinoma
-
A. Villanueva, P. Newell, D.Y. Chiang, S.L. Friedman, J.M. Llovet, Genomics and signaling pathways in hepatocellular carcinoma. Semin. Liver Dis. 27, 55-76 (2007)
-
(2007)
Semin. Liver Dis
, vol.27
, pp. 55-76
-
-
Villanueva, A.1
Newell, P.2
Chiang, D.Y.3
Friedman, S.L.4
Llovet, J.M.5
-
37
-
-
75449092617
-
Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumorstroma cross-talk and tumor progression in hepatocellular carcinoma
-
A. Mazzocca, E. Fransvea, F. Dituri, L. Lupo, S. Antonaci, G. Giannelli, Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumorstroma cross-talk and tumor progression in hepatocellular carcinoma. Hepatology 51, 523-534 (2010)
-
(2010)
Hepatology
, vol.51
, pp. 523-534
-
-
Mazzocca, A.1
Fransvea, E.2
Dituri, F.3
Lupo, L.4
Antonaci, S.5
Giannelli, G.6
-
38
-
-
12144291647
-
Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth HepG2 and Morris 5123 liver cancer cells
-
DOI 10.1093/carcin/bgh014
-
M.M. Simile, M.R. De Miglio, M.R. Muroni, S. Pusceddu, D. Calvisi, A. Carru, M.A. Seddaiu, L. Daino, L. Deiana, R.M. Pascale, F. Feo, Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells. Carcinogenesis 25, 333-341 (2004) (Pubitemid 38344399)
-
(2004)
Carcinogenesis
, vol.25
, Issue.3
, pp. 333-341
-
-
Simile, M.M.1
De Miglio, M.R.2
Muroni, M.R.3
Frau, M.4
Asara, G.5
Serra, S.6
Muntoni, M.D.7
Seddaiu, M.A.8
Daino, L.9
Feo, F.10
Pascale, R.M.11
-
39
-
-
7744220635
-
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
-
DOI 10.1038/nature03043
-
C.M. Shachaf, A.M. Kopelman, C. Arvanitis, A. Karlsson, S. Beer, S. Mandl, M.H. Bachman, A.D. Borowsky, B. Ruebner, R.D. Cardiff, Q. Yang, J.M. Bishop, C.H. Contag, D.W. Felsher, MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 431, 1112-1117 (2004) (Pubitemid 39472236)
-
(2004)
Nature
, vol.431
, Issue.7012
, pp. 1112-1117
-
-
Shachaf, C.M.1
Kopelman, A.M.2
Arvanitis, C.3
Karlsson, A.4
Beer, S.5
Mandl, S.6
Bachmann, M.H.7
Borowsky, A.D.8
Ruebner, B.9
Cardiff, R.D.10
Yang, Q.11
Bishop, J.M.12
Contag, C.H.13
Felsher, D.W.14
-
40
-
-
0033658966
-
Reduced mrna abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma
-
M.A. Avila, C. Berasain, L. Torres, A. Martín-Duce, F.J. Corrales, H. Yang, J. Prieto, S.C. Lu, J. Caballería, J. Rodés, J.M. Mato, Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma. J. Hepatol. 33, 907-914 (2000)
-
(2000)
J. Hepatol
, vol.33
, pp. 907-914
-
-
Avila, M.A.1
Berasain, C.2
Torres, L.3
Martín-Duce, A.4
Corrales, F.J.5
Yang, H.6
Prieto, J.7
Lu, S.C.8
Caballería, J.9
Rodés, J.10
Mato, J.M.11
-
41
-
-
79551586473
-
Loss of dmbt1 expression in human prostate cancer and its correlation with clinical progressive features
-
J. Du, M. Guan, J. Fan, H. Jiang, Loss of DMBT1 expression in human prostate cancer and its correlation with clinical progressive features. Urology 77(509), e9-e13 (2011)
-
(2011)
Urology
, vol.77
, Issue.509
-
-
Du, J.1
Guan, M.2
Fan, J.3
Jiang, H.4
-
42
-
-
10744233765
-
Decrease of Deleted in Malignant Brain Tumour-1 (DMBT-1) expression is a crucial late event in intrahepatic cholangiocarcinoma
-
DOI 10.1046/j.1365-2559.2003.01719.x
-
M. Sasaki, S.F. Huang, M.F. Chen, Y.Y. Jan, T.S. Yeh, A. Ishikawa, J. Mollenhauer, A. Poustka, K. Tsuneyama, Y. Nimura, K. Oda, Y. Nakanuma, Decrease of deleted in malignant brain tumour-1 (DMBT-1) expression is a crucial late event in intrahepatic cholangiocarcinoma. Histopathology 43, 340-346 (2003) (Pubitemid 37249147)
-
(2003)
Histopathology
, vol.43
, Issue.4
, pp. 340-346
-
-
Sasaki, M.1
Huang, S.-F.2
Chen, M.-F.3
Jan, Y.-Y.4
Yeh, T.-S.5
Ishikawa, A.6
Mollenhauer, J.7
Poustka, A.8
Tsuneyama, K.9
Nimura, Y.10
Oda, K.11
Nakanuma, Y.12
-
43
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
J.S. Lee, J. Heo, L. Libbrecht, I.S. Chu, P. Kaposi-Novak, D.F. Calvisi, A. Mikaelyan, L.R. Roberts, A.J. Demetris, Z. Sun, F. Nevens, T. Roskams, S.S. Thorgeirsson, A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat. Med. 12, 410-416 (2006)
-
(2006)
Nat. Med
, vol.12
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
Chu, I.S.4
Kaposi-Novak, P.5
Calvisi, D.F.6
Mikaelyan, A.7
Roberts, L.R.8
Demetris, A.J.9
Sun, Z.10
Nevens, F.11
Roskams, T.12
Thorgeirsson, S.S.13
-
44
-
-
33745220780
-
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
-
P. Kaposi-Novak, J.S. Lee, L. Gòmez-Quiroz, C. Coulouarn, V.M. Factor, S.S. Thorgeirsson, Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. J. Clin. Invest. 116, 1582-1595 (2006)
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1582-1595
-
-
Kaposi-Novak, P.1
Lee, J.S.2
Gòmez-Quiroz, L.3
Coulouarn, C.4
Factor, V.M.5
Thorgeirsson, S.S.6
-
45
-
-
57349090407
-
Gene expression in fixed tissues and outcome in hepatocellular carcinoma
-
Y. Hoshida, A. Villanueva, M. Kobayashi, J. Peix, D.Y. Chiang, A. Camargo, S. Gupta, J. Moore, M.J. Wrobel, J. Lerner, M. Reich, J.A. Chan, J.N. Glickman, K. Ikeda, M. Hashimoto, G. Watanabe, M.G. Daidone, S. Roayaie, M. Schwartz, S. Thung, H.B. Salvesen, S. Gabriel, V. Mazzaferro, J. Bruix, S.L. Friedman, H. Kumada, J.M. Llovet, T.R. Golub, Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N. Engl. J. Med. 359, 1995-2004 (2008)
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 1995-2004
-
-
Hoshida, Y.1
Villanueva, A.2
Kobayashi, M.3
Peix, J.4
Chiang, D.Y.5
Camargo, A.6
Gupta, S.7
Moore, J.8
Wrobel, M.J.9
Lerner, J.10
Reich, M.11
Chan, J.A.12
Glickman, J.N.13
Ikeda, K.14
Hashimoto, M.15
Watanabe, G.16
Daidone, M.G.17
Roayaie, S.18
Schwartz, M.19
Thung, S.20
Salvesen, H.B.21
Gabriel, S.22
Mazzaferro, V.23
Bruix, J.24
Friedman, S.L.25
Kumada, H.26
Llovet, J.M.27
Golub, T.R.28
more..
-
46
-
-
40849124295
-
Novel advancements in the management of hepatocellular carcinoma in 2008
-
J.M. Llovet, J. Bruix, Novel advancements in the management of hepatocellular carcinoma in 2008. J. Hepatol. 48(Suppl 1), S20-S37 (2008)
-
(2008)
J. Hepatol
, vol.48
, Issue.SUPPL. 1
-
-
Llovet, J.M.1
Bruix, J.2
-
47
-
-
25844461787
-
Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling
-
DOI 10.1002/hep.20878
-
S.W. Nam, J.Y. Park, A. Ramasamy, S. Shevade, A. Islam, P.M. Long, C.K. Park, S.E. Park, S.Y. Kim, S.H. Lee, W.S. Park, N.J. Yoo, E.T. Liu, L.D. Miller, J.Y. Lee, Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology 42, 809-818 (2005) (Pubitemid 41401118)
-
(2005)
Hepatology
, vol.42
, Issue.4
, pp. 809-818
-
-
Nam, S.W.1
Park, J.Y.2
Ramasamy, A.3
Shevade, S.4
Islam, A.5
Long, P.M.6
Park, C.K.7
Park, S.E.8
Kim, S.Y.9
Lee, S.H.10
Park, W.S.11
Yoo, N.J.12
Liu, E.T.13
Miller, L.D.14
Lee, J.Y.15
-
48
-
-
33845790499
-
A Molecular Signature to Discriminate Dysplastic Nodules From Early Hepatocellular Carcinoma in HCV Cirrhosis
-
DOI 10.1053/j.gastro.2006.09.014, PII S0016508506020749
-
J.M. Llovet, Y. Chen, E. Wurmbach, S. Roayaie, M.I. Fiel, M. Schwartz, S.N. Thung, G. Khitrov, W. Zhang, A. Villanueva, C. Battiston, V. Mazzaferro, J. Bruix, S. Waxman, S.L. Friedman, A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis. Gastroenterology 131, 1758-1767 (2006) (Pubitemid 46001394)
-
(2006)
Gastroenterology
, vol.131
, Issue.6
, pp. 1758-1767
-
-
Llovet, J.M.1
Chen, Y.2
Wurmbach, E.3
Roayaie, S.4
Fiel, M.I.5
Schwartz, M.6
Thung, S.N.7
Khitrov, G.8
Zhang, W.9
Villanueva, A.10
Battiston, C.11
Mazzaferro, V.12
Bruix, J.13
Waxman, S.14
Friedman, S.L.15
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