The aspartic protease napsin a suppresses tumor growth independent of its catalytic activity

Laboratory Investigation

Volumn 88, Issue 3, 2008, Pages 256-263

  Ueno, Takayuki ^a,c   Elmberger, Göran ^a   Weaver, Timothy E ^b   Toi, Masakazu ^c   Linder, Stig ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Aspartic protease; Napsin A; Renal cell carcinoma; Tumor suppression

Indexed keywords

ASPARTIC PROTEINASE; NAPSIN A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATALYSIS; COLONY FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; GLYCOSYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; KIDNEY CARCINOMA; KIDNEY PROXIMAL TUBULE; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TUMOR GROWTH;

ANIMALS; ASPARTIC ENDOPEPTIDASES; CARCINOMA, HEPATOCELLULAR; CATALYSIS; CELL CULTURE TECHNIQUES; CELL LINE; CELL PROLIFERATION; CLONE CELLS; COLLAGEN; DNA, COMPLEMENTARY; HISTIDINE; HUMANS; KIDNEY; LIVER NEOPLASMS; MICE; MICE, SCID; MUTATION; NEOPLASMS; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN;

EID: 39749140202     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700718     Document Type: Article

References (33)