Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology

DMM Disease Models and Mechanisms

Volumn 5, Issue 6, 2012, Pages 823-833

  Greenhalgh, Andrew D ^a,b   Brough, David ^a   Robinson, Emily M ^a   Girard, Sylvie ^a   Rothwell, Nancy J ^a   Allan, Stuart M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; GAMMA INTERFERON; HEME; HEME OXYGENASE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INJURY; CONTROLLED STUDY; EXTRAVASATION; GLIA CELL; IN VITRO STUDY; MALE; MICROGLIA; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE; SUBARACHNOID SPACE;

ANIMALS; BLOOD-BRAIN BARRIER; DISEASE MODELS, ANIMAL; ERYTHROCYTES; HEME; HEME OXYGENASE-1; HEMIN; HEMOLYSIS; HUMANS; INFLAMMATION; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; MACROPHAGES; MALE; MICE; MICROGLIA; NEURONS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE;

ANIMALIA; RATTUS;

EID: 84870024389     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.008557     Document Type: Article

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