-
1
-
-
84862984571
-
Finding cancer's weakest link
-
N.M. Sodir, G.I. Evan, Finding cancer's weakest link. Oncotarget 2, 1307-1313 (2011)
-
(2011)
Oncotarget
, vol.2
, pp. 1307-1313
-
-
Sodir, N.M.1
Evan, G.I.2
-
2
-
-
79551629227
-
Searching for synthetic lethality in cancer
-
R. Brough, J.R. Frankum, S. Costa-Cabral, C.J. Lord, A. Ashworth, Searching for synthetic lethality in cancer. Curr. Opin. Genet. Dev. 21, 34-41 (2011)
-
(2011)
Curr. Opin. Genet. Dev
, vol.21
, pp. 34-41
-
-
Brough, R.1
Frankum, J.R.2
Costa-Cabral, S.3
Lord, C.J.4
Ashworth, A.5
-
3
-
-
84856069665
-
A sumoylation-dependent transcriptional subprogram is required for myc-driven tumorigenesis
-
J.D. Kessler, K.T. Kahle, T. Sun, K.L. Meerbrey, M.R. Schlabach, E.M. Schmitt, S.O. Skinner, Q. Xu, M.Z. Li, Z.C. Hartman, M. Rao, P. Yu, R. Dominguez-Vidana, A.C. Liang, N.L. Solimini, R.J. Bernardi, B. Yu, T. Hsu, I. Golding, J. Luo, C.K. Osborne, C.J. Creighton, S.G. Hilsenbeck, R. Schiff, C.A. Shaw, S.J. Elledge, T.F. Westbrook, A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science 335, 348-353 (2012)
-
(2012)
Science
, vol.335
, pp. 348-353
-
-
Kessler, J.D.1
Kahle, K.T.2
Sun, T.3
Meerbrey, K.L.4
Schlabach, M.R.5
Schmitt, E.M.6
Skinner, S.O.7
Xu, Q.8
Li, M.Z.9
Hartman, Z.C.10
Rao, M.11
Yu, P.12
Dominguez-Vidana, R.13
Liang, A.C.14
Solimini, N.L.15
Bernardi, R.J.16
Yu, B.17
Hsu, T.18
Golding, I.19
Luo, J.20
Osborne, C.K.21
Creighton, C.J.22
Hilsenbeck, S.G.23
Schiff, R.24
Shaw, C.A.25
Elledge, S.J.26
Westbrook, T.F.27
more..
-
4
-
-
84856073641
-
Taking a backdoor to target myc
-
G. Evan, Taking a backdoor to target Myc. Science 335, 293-294 (2012)
-
(2012)
Science
, vol.335
, pp. 293-294
-
-
Evan, G.1
-
5
-
-
23244447037
-
E600-associated senescence-like cell cycle arrest of human naevi
-
DOI 10.1038/nature03890
-
C. Michaloglou, L.C. Vredeveld, M.S. Soengas, C. Denoyelle, T. Kuilman, C.M. van der Horst, D.M. Majoor, J.W. Shay,W.J. Mooi, D.S. Peeper, BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 436, 720-724 (2005) (Pubitemid 41117276)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.W.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
Van Der Horst, C.M.A.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
6
-
-
81855169964
-
Senescence surveillance of premalignant hepatocytes limits liver cancer development
-
T.W. Kang, T. Yevsa, N. Woller, L. Hoenicke, T. Wuestefeld, D. Dauch, A. Hohmeyer, M. Gereke, R. Rudalska, A. Potapova, M. Iken, M. Vucur, S. Weiss, M. Heikenwalder, S. Khan, J. Gil, D. Bruder, M. Manns, P. Schirmacher, F. Tacke, M. Ott, T. Luedde, T. Longerich, S. Kubicka, L. Zender, Senescence surveillance of premalignant hepatocytes limits liver cancer development. Nature 479, 547-551 (2011)
-
(2011)
Nature
, vol.479
, pp. 547-551
-
-
Kang, T.W.1
Yevsa, T.2
Woller, N.3
Hoenicke, L.4
Wuestefeld, T.5
Dauch, D.6
Hohmeyer, A.7
Gereke, M.8
Rudalska, R.9
Potapova, A.10
Iken, M.11
Vucur, M.12
Weiss, S.13
Heikenwalder, M.14
Khan, S.15
Gil, J.16
Bruder, D.17
Manns, M.18
Schirmacher, P.19
Tacke, F.20
Ott, M.21
Luedde, T.22
Longerich, T.23
Kubicka, S.24
Zender, L.25
more..
-
7
-
-
81855212708
-
Final act of senescence
-
M. Serrano, Final act of senescence. Nature 479, 481-482 (2011)
-
(2011)
Nature
, vol.479
, pp. 481-482
-
-
Serrano, M.1
-
8
-
-
69349103956
-
The ink4/arf locus is a barrier for ips cell programming
-
H. Li, M. Collado, A. Villasante, K. Strati, S. Ortega, M. Cañamero, M.A. Blasco, M. Serrano, The Ink4/Arf locus is a barrier for iPS cell programming. Nature 460, 1136-1139 (2009)
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
Collado, M.2
Villasante, A.3
Strati, K.4
Ortega, S.5
Cañamero, M.6
Blasco, M.A.7
Serrano, M.8
-
9
-
-
84855824670
-
Increased dosage of tumor suppressors limits the tumorigenicity of ips cells without affecting their pluripotency
-
S. Menendez, S. Camus, A. Herreria, I. Paramonov, L.B. Morera, M. Collado, V. Pekarik, I. Maceda, M. Edel, A. Consiglio, A. Sanchez, H. Li, M. Serrano, J.C. Belmonte, Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency. Aging Cell 11, 41-50 (2012)
-
(2012)
Aging Cell
, vol.11
, pp. 41-50
-
-
Menendez, S.1
Camus, S.2
Herreria, A.3
Paramonov, I.4
Morera, L.B.5
Collado, M.6
Pekarik, V.7
Maceda, I.8
Edel, M.9
Consiglio, A.10
Sanchez, A.11
Li, H.12
Serrano, M.13
Belmonte, J.C.14
-
10
-
-
77954840147
-
Intracellular antibodies and cancer: New technologies offer therapeutic opportunities
-
D. Pérez-Martínez, T. Tanaka, T.H. Rabbitts, Intracellular antibodies and cancer: new technologies offer therapeutic opportunities. Bioassays 32, 589-598 (2010)
-
(2010)
Bioassays
, vol.32
, pp. 589-598
-
-
Pérez-Martínez, D.1
Tanaka, T.2
Rabbitts, T.H.3
-
11
-
-
0035122485
-
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
-
DOI 10.1038/84683
-
P. Vigneri, J.Y.Wang, Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nat. Med. 7, 228-234 (2001) (Pubitemid 32148491)
-
(2001)
Nature Medicine
, vol.7
, Issue.2
, pp. 228-234
-
-
Vigneri, P.1
Wang, J.Y.J.2
-
12
-
-
84862685624
-
Changing the subcellular location of the oncoprotein bcr-abl using rationally designed capture motifs
-
A.S. Dixon, J.E. Constance, T. Tanaka, T.H. Rabbitts, C.S. Lim, Changing the subcellular location of the oncoprotein bcr-abl using rationally designed capture motifs. Pharm. Res. 29, 1098-1109 (2012)
-
(2012)
Pharm. Res
, vol.29
, pp. 1098-1109
-
-
Dixon, A.S.1
Constance, J.E.2
Tanaka, T.3
Rabbitts, T.H.4
Lim, C.S.5
-
13
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
S.A. Tomlins, D.R. Rhodes, S. Perner, S.M. Dhanasekaran, R. Mehra, X.W. Sun, S. Varambally, X. Cao, J. Tchinda, R. Kuefer, C. Lee, J.E. Montie, R.B. Shah, K.J. Pienta, M.A. Rubin, A.M. Chinnaiyan, Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310, 644-648 (2005) (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
14
-
-
84858448028
-
Are breast cancers driven by fusion genes?
-
P.A. Edwards, K.D. Howarth, Are breast cancers driven by fusion genes? Breast Cancer Res. 14, 303 (2012)
-
(2012)
Breast Cancer Res
, vol.14
, pp. 303
-
-
Edwards, P.A.1
Howarth, K.D.2
-
15
-
-
84856091317
-
Functionally recurrent rearrangements of the mast kinase and notch gene families in breast cancer
-
D.R. Robinson, S. Kalyana-Sundaram, Y.M. Wu, S. Shankar, X. Cao, B. Ateeq, I.A. Asangani, M. Iyer, C.A. Maher, C.S. Grasso, R.J. Lonigro, M. Quist, J. Siddiqui, R. Mehra, X. Jing, T.J. Giordano, M.S. Sabel, C.G. Kleer, N. Palanisamy, R. Natrajan, M.B. Lambros, J.S. Reis-Filho, C. Kumar-Sinha, A.M. Chinnaiyan, Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. Nat. Med. 17, 1646-1651 (2011)
-
(2011)
Nat. Med
, vol.17
, pp. 1646-1651
-
-
Robinson, D.R.1
Kalyana-Sundaram, S.2
Wu, Y.M.3
Shankar, S.4
Cao, X.5
Ateeq, B.6
Asangani, I.A.7
Iyer, M.8
Maher, C.A.9
Grasso, C.S.10
Lonigro, R.J.11
Quist, M.12
Siddiqui, J.13
Mehra, R.14
Jing, X.15
Giordano, T.J.16
Sabel, M.S.17
Kleer, C.G.18
Palanisamy, N.19
Natrajan, R.20
Lambros, M.B.21
Reis-Filho, J.S.22
Kumar-Sinha, C.23
Chinnaiyan, A.M.24
more..
-
16
-
-
79551661935
-
Cell-typespecific replication initiation programs set fragility of the fra3b fragile site
-
A. Letessier, G.A. Millot, S. Koundrioukoff, A.M. Lachagès, N. Vogt, R.S. Hansen, B. Malfoy, O. Brison, M. Debatisse, Cell-typespecific replication initiation programs set fragility of the FRA3B fragile site. Nature 470, 120-123 (2011)
-
(2011)
Nature
, vol.470
, pp. 120-123
-
-
Letessier, A.1
Millot, G.A.2
Koundrioukoff, S.3
Lachagès, A.M.4
Vogt, N.5
Hansen, R.S.6
Malfoy, B.7
Brison, O.8
Debatisse, M.9
-
17
-
-
82955195401
-
Molecular profiling of common fragile sites in human fibroblasts
-
B. Le Tallec, B. Dutrillaux, A.M. Lachages, G.A. Millot, O. Brison, M. Debatisse, Molecular profiling of common fragile sites in human fibroblasts. Nat. Struct. Mol. Biol. 18, 1421-1423 (2011)
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 1421-1423
-
-
Le Tallec, B.1
Dutrillaux, B.2
Lachages, A.M.3
Millot, G.A.4
Brison, O.5
Debatisse, M.6
-
18
-
-
84655167711
-
Common fragile sites: Mechanisms of instability revisited
-
M. Debatisse, B. Le Tallec, A. Letessier, B. Dutrillaux, O. Brison, Common fragile sites: mechanisms of instability revisited. Trends Genet. 28, 22-32 (2012)
-
(2012)
Trends Genet
, vol.28
, pp. 22-32
-
-
Debatisse, M.1
Le Tallec, B.2
Letessier, A.3
Dutrillaux, B.4
Brison, O.5
-
19
-
-
58149334818
-
Genome stability is ensured by temporal control of kinetochoremicrotubule dynamics
-
S.F. Bakhoum, S.L. Thompson, A.L. Manning, D.A. Compton, Genome stability is ensured by temporal control of kinetochoremicrotubule dynamics. Nat. Cell. Biol. 11, 27-35 (2009)
-
(2009)
Nat. Cell. Biol
, vol.11
, pp. 27-35
-
-
Bakhoum, S.F.1
Thompson, S.L.2
Manning, A.L.3
Compton, D.A.4
-
20
-
-
84859587548
-
Checkpoint-independent stabilization of kinetochore-microtubule attachments by mad2 in human cells
-
L. Kabeche, D.A. Compton, Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells. Curr. Biol. [Epub ahead of print] (2012)
-
(2012)
Curr. Biol. [Epub ahead of print]
-
-
Kabeche, L.1
Compton, D.A.2
-
21
-
-
79953174923
-
Spindle-assembly checkpoint and gastrointestinal cancer
-
R. de Voer, N. Hoogerbrugge, R.P. Kuiper, Spindle-assembly checkpoint and gastrointestinal cancer. New Eng. J. Med. 364, 1279-1280 (2010)
-
(2010)
New Eng. J. Med
, vol.364
, pp. 1279-1280
-
-
De Voer, R.1
Hoogerbrugge, N.2
Kuiper, R.P.3
-
22
-
-
80053364894
-
Chromosome segregation errors as a cause of dna damage and structural chromosome aberrations
-
A. Janssen, M. van der Burg, K. Szuhai, G.J.P.L. Kops, R. Medema, Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science 333, 1895-1898 (2011)
-
(2011)
Science
, vol.333
, pp. 1895-1898
-
-
Janssen, A.1
Van Der Burg, M.2
Szuhai, K.3
Kops, G.J.P.L.4
Medema, R.5
-
24
-
-
84857996064
-
The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer
-
C.K. Ng, S.L. Cooke, K. Howe, S. Newman, J. Xian, J. Temple, E.M. Batty, J.C. Pole, S.P. Langdon, P.A. Edwards, J.D. Brenton, The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer. J. Pathol. 226, 703-712 (2012)
-
(2012)
J. Pathol
, vol.226
, pp. 703-712
-
-
Ng, C.K.1
Cooke, S.L.2
Howe, K.3
Newman, S.4
Xian, J.5
Temple, J.6
Batty, E.M.7
Pole, J.C.8
Langdon, S.P.9
Edwards, P.A.10
Brenton, J.D.11
-
25
-
-
84859216598
-
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
-
J.J. Molenaar, J. Koster, D.A. Zwijnenburg, P. van Sluis, L.J. Valentijn, I. van der Ploeg, M. Hamdi, J. van Nes, B.A. Westerman, J. van Arkel, M.E. Ebus, F. Haneveld, A. Lakeman, L. Schild, P. Molenaar, P. Stroeken, M.M. van Noesel, I. Ora, E.E. Santo, H.N. Caron, E.M. Westerhout, R. Versteeg, Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature 483, 589-593 (2012)
-
(2012)
Nature
, vol.483
, pp. 589-593
-
-
Molenaar, J.J.1
Koster, J.2
Zwijnenburg, D.A.3
Van Sluis, P.4
Valentijn, L.J.5
Van Der Ploeg, I.6
Hamdi, M.7
Van Nes, J.8
Westerman, B.A.9
Van Arkel, J.10
Ebus, M.E.11
Haneveld, F.12
Lakeman, A.13
Schild, L.14
Molenaar, P.15
Stroeken, P.16
Van Noesel, M.M.17
Ora, I.18
Santo, E.E.19
Caron, H.N.20
Westerhout, E.M.21
Versteeg, R.22
more..
-
26
-
-
84856890649
-
Investigation of the effects of dna repair gene polymorphisms on the risk of colorectal cancer
-
I.P. Tomlinson, R.S. Houlston, G.W. Montgomery, O.M. Sieber, M.G. Dunlop, Investigation of the effects of DNA repair gene polymorphisms on the risk of colorectal cancer. Mutagenesis 27, 219-223 (2012)
-
(2012)
Mutagenesis
, vol.27
, pp. 219-223
-
-
Tomlinson, I.P.1
Houlston, R.S.2
Montgomery, G.W.3
Sieber, O.M.4
Dunlop, M.G.5
-
27
-
-
85081077587
-
Members of cogent. Cogent (colorectal cancer genetics) revisited
-
R.S. Houlston, members of COGENT. COGENT (COlorectal cancer GENeTics) revisited. Mutagenesis 27, 143-151 (2012)
-
(2012)
Mutagenesis
, vol.27
, pp. 143-151
-
-
Houlston, R.S.1
-
28
-
-
84863230211
-
Transcription profiling by sequencing of oropharyngeal cancer
-
R.R. Laborde, V.W. Wang, T.M. Smith, N.E. Olson, S.M. Olsen, J.J. García, K.D. Olsen, E.J. Moore, J.L. Kasperbauer, N.M. Tombers, D.I. Smith, Transcription profiling by sequencing of oropharyngeal cancer. Mayo Clinic Proc. 87, 226-232 (2012)
-
(2012)
Mayo Clinic Proc
, vol.87
, pp. 226-232
-
-
Laborde, R.R.1
Wang, V.W.2
Smith, T.M.3
Olson, N.E.4
Olsen, S.M.5
García, J.J.6
Olsen, K.D.7
Moore, E.J.8
Kasperbauer, J.L.9
Tombers, N.M.10
Smith, D.I.11
-
29
-
-
79958172285
-
Fusion hunter: Identifying transcripts in cancer using paired-end rna-seq
-
T. Li, J. Chien, D.I. Smith, J. Ma, Fusion hunter: identifying transcripts in cancer using paired-end RNA-seq. Bioinformatics 27, 1708-1710 (2011)
-
(2011)
Bioinformatics
, vol.27
, pp. 1708-1710
-
-
Li, T.1
Chien, J.2
Smith, D.I.3
Ma, J.4
-
30
-
-
0037025173
-
Cancer: Addiction to oncogenes - The Achilles heal of cancer
-
DOI 10.1126/science.1073096
-
I.B. Weinstein, Addiction to oncogenes -the achilles heal of cancer. Science 297, 63-64 (2002) (Pubitemid 34743088)
-
(2002)
Science
, vol.297
, Issue.5578
, pp. 63-64
-
-
Weinstein, I.B.1
-
31
-
-
79952833775
-
Myc inactivation elicits oncogene addiction through both tumor cell-intrinsic and host-dependent mechanisms
-
D.W. Felsher, MYC inactivation elicits oncogene addiction through both tumor cell-intrinsic and host-dependent mechanisms. Genes Cancer 1, 597-604 (2010)
-
(2010)
Genes Cancer
, vol.1
, pp. 597-604
-
-
Felsher, D.W.1
-
32
-
-
80053649037
-
Survival and death signals can predict tumor response to therapy after oncogene activation
-
P.T. Tran, P.K. Bendapudi, H.J. Lin, P. Choi, S. Koh, J. Chen, G. Horng, N.P. Hughes, L.H. Schwartz, V.A. Miller, T. Kawashima, T. Kitamura, D. Paik, D.W. Felsher, Survival and death signals can predict tumor response to therapy after oncogene activation. Sci. Transl. Med. 3, 103ra99 (2011)
-
(2011)
Sci. Transl. Med
, vol.3
-
-
Tran, P.T.1
Bendapudi, P.K.2
Lin, H.J.3
Choi, P.4
Koh, S.5
Chen, J.6
Horng, G.7
Hughes, N.P.8
Schwartz, L.H.9
Miller, V.A.10
Kawashima, T.11
Kitamura, T.12
Paik, D.13
Felsher, D.W.14
-
33
-
-
82555176606
-
Immunotherapy: A first for first-line therapy in nsclc
-
R. Kirk, Immunotherapy: a first for first-line therapy in NSCLC. Nat. Rev. Clin. Oncol. 8, 691 (2011)
-
Nat. Rev. Clin. Oncol
, vol.8
, Issue.691
, pp. 2011
-
-
Kirk, R.1
-
34
-
-
84860534759
-
Mechanisms regulating epidermal stem cells
-
[Epub ahead of print]
-
B. Beck, C. Blanpain, Mechanisms regulating epidermal stem cells. EMBO J. [Epub ahead of print] (2012)
-
(2012)
EMBO J
-
-
Beck, B.1
Blanpain, C.2
-
35
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
-
B. Gan, J. Hu, S. Jiang, Y. Liu, E. Sahin, L. Zhuang, E. Fletcher-Sananikone, S. Colla, Y.A. Wang, L. Chin, R.A. Depinho, Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468, 701-704 (2010)
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
Hu, J.2
Jiang, S.3
Liu, Y.4
Sahin, E.5
Zhuang, L.6
Fletcher-Sananikone, E.7
Colla, S.8
Wang, Y.A.9
Chin, L.10
Depinho, R.A.11
-
36
-
-
84855425160
-
Interactions between cancer stem cells and their niche govern metastatic colonization
-
I. Malanchi, A. Santamaria-Martínez, E. Susanto, H. Peng, H.A. Lehr, J.F. Delaloye, J. Huelsken, Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 481, 85-89 (2012)
-
(2012)
Nature
, vol.481
, pp. 85-89
-
-
Malanchi, I.1
Santamaria-Martínez, A.2
Susanto, E.3
Peng, H.4
Lehr, H.A.5
Delaloye, J.F.6
Huelsken, J.7
-
37
-
-
84855466019
-
Icon7 investigators. A phase 3 trial of bevacizumab in ovarian cancer
-
T.J. Perren, A.M. Swart, J. Pfisterer, J.A. Ledermann, E. Pujade-Lauraine, G. Kristensen, M.S. Carey, P. Beale, A. Cervantes, C. Kurzeder, A. du Bois, J. Sehouli, R. Kimmig, A. Stähle, F. Collinson, S. Essapen, C. Gourley, A. Lortholary, F. Selle, M.R. Mirza, A. Leminen, M. Plante, D. Stark, W. Qian, M.K. Parmar, A.M. Oza, ICON7 Investigators. A phase 3 trial of bevacizumab in ovarian cancer. New Eng. J. Med. 365, 1484-2496 (2011)
-
(2011)
New Eng. J. Med
, vol.365
, pp. 1484-2496
-
-
Perren, T.J.1
Swart, A.M.2
Pfisterer, J.3
Ledermann, J.A.4
Pujade-Lauraine, E.5
Kristensen, G.6
Carey, M.S.7
Beale, P.8
Cervantes, A.9
Kurzeder, C.10
Du Bois, A.11
Sehouli, J.12
Kimmig, R.13
Stähle, A.14
Collinson, F.15
Essapen, S.16
Gourley, C.17
Lortholary, A.18
Selle, F.19
Mirza, M.R.20
Leminen, A.21
Plante, M.22
Stark, D.23
Qian, W.24
Parmar, M.K.25
Oza, A.M.26
more..
-
38
-
-
81755187274
-
Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration
-
V.P. Chauhan, Z. Popovic, O. Chen, J. Cui, D. Fukumura, M.G. Bawendi, R.K. Jain, Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration. Angew. Chem. Int. Ed. 50, 11417-11420 (2011)
-
(2011)
Angew. Chem. Int. Ed
, vol.50
, pp. 11417-11420
-
-
Chauhan, V.P.1
Popovic, Z.2
Chen, O.3
Cui, J.4
Fukumura, D.5
Bawendi, M.G.6
Jain, R.K.7
-
39
-
-
84872602365
-
Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1
-
[Epub ahead of print]
-
J.R. van Beijnum, P. Nowak-Sliwinska, E. van den Boezem, P. Hautvast, W.A. Buurman, A.W. Griffioen. Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1. Oncogene [Epub ahead of print] (2012)
-
(2012)
Oncogene
-
-
Van Beijnum, J.R.1
Nowak-Sliwinska, P.2
Van Den Boezem, E.3
Hautvast, P.4
Buurman, W.A.5
Griffioen, A.W.6
-
40
-
-
84858699025
-
Dual-targeting of avß3 and galectin-1 improves the specificity of paramagnetic/fluorescent liposomes to tumor endothelium in vivo
-
E. Kluza, I. Jacobs, S.J. Hectors, K.H. Mayo, A.W. Griffioen, G.J. Strijkers, K. Nicolay, Dual-targeting of avß3 and galectin-1 improves the specificity of paramagnetic/fluorescent liposomes to tumor endothelium in vivo. J. Contr. Release 158, 207-214 (2012)
-
(2012)
J. Contr. Release
, vol.158
, pp. 207-214
-
-
Kluza, E.1
Jacobs, I.2
Hectors, S.J.3
Mayo, K.H.4
Griffioen, A.W.5
Strijkers, G.J.6
Nicolay, K.7
-
41
-
-
33749332105
-
Gene expression of tumor angiogenesis dissected: Specific targeting of colon cancer angiogenic vasculature
-
DOI 10.1182/blood-2006-02-004291
-
J.R. van Beijnum, R.P. Dings, E. van der Linden, B.M. Zwaans, F.C. Ramaekers, K.H. Mayo, A.W. Griffioen, Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature. Blood 108, 2339-2348 (2006) (Pubitemid 44497518)
-
(2006)
Blood
, vol.108
, Issue.7
, pp. 2339-2348
-
-
Van Beijnum, J.R.1
Dings, R.P.2
Van Der Linden, E.3
Zwaans, B.M.M.4
Ramaekers, F.C.S.5
Mayo, K.H.6
Griffioen, A.W.7
-
42
-
-
84859498670
-
Angiogenesis inhibition for the improvement of photodynamic therapy: The revival of a promising idea
-
A. Weiss, H.V. den Bergh, A.W. Griffioen, P. Nowak-Sliwinska, Angiogenesis inhibition for the improvement of photodynamic therapy: the revival of a promising idea. Biochim. Biophys. Acta. 1826, 53-70 (2012)
-
(2012)
Biochim. Biophys. Acta
, vol.1826
, pp. 53-70
-
-
Weiss, A.1
Den Bergh, H.V.2
Griffioen, A.W.3
Nowak-Sliwinska, P.4
-
43
-
-
18544364773
-
Cancer epigenetics and methylation
-
M. Esteller, M.F. Fraga, M.F. Paz, E. Campo, D. Colomer, F.J. Novo, M.J. Calasanz, O. Ga, M. Guo, J. Benitez, J.G. Herman, Cancer epigenetics and methylation. Science 297, 1807-1808 (2002)
-
(2002)
Science
, vol.297
, pp. 1807-1808
-
-
Esteller, M.1
Fraga, M.F.2
Paz, M.F.3
Campo, E.4
Colomer, D.5
Novo, F.J.6
Calasanz, M.J.7
Ga, O.8
Guo, M.9
Benitez, J.10
Herman, J.G.11
-
44
-
-
67649876132
-
Acquired mutations in tet2 are common in myelodysplastic syndromes
-
S.M. Langemeijer, R.P. Kuiper, M. Berends, R. Knops, M.G. Aslanyan, M. Massop, E. Stevens-Linders, P. van Hoogen, A. Geurts van Kessel, R.A. Raymakers, E.J. Kamping, G.E. Verhoef, E. Verburgh, A. Hagemeijer, P. Vandenberghe, T. de Witte, B.A. van der Reijden, J.H. Jansen, Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat. Genet. 41, 838-842 (2009)
-
(2009)
Nat. Genet
, vol.41
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
Knops, R.4
Aslanyan, M.G.5
Massop, M.6
Stevens-Linders, E.7
Van Hoogen, P.8
Geurts Van Kessel, A.9
Raymakers, R.A.10
Kamping, E.J.11
Verhoef, G.E.12
Verburgh, E.13
Hagemeijer, A.14
Vandenberghe, P.15
De Witte, T.16
Van Der Reijden, B.A.17
Jansen, J.H.18
-
45
-
-
77955087290
-
Somatic mutations of the histone methyltransferase gene ezh2 in myelodysplastic syndromes
-
G. Nikoloski, S.M. Langemeijer, R.P. Kuiper, R. Knops, M. Massop, E.R. Tönnissen, A. van der Heijden, T.N. Scheele, P. Vandenberghe, T. de Witte, B.A. van der Reijden, J.H. Jansen, Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes. Nat. Genet. 42, 665-667 (2010)
-
(2010)
Nat. Genet
, vol.42
, pp. 665-667
-
-
Nikoloski, G.1
Langemeijer, S.M.2
Kuiper, R.P.3
Knops, R.4
Massop, M.5
Tönnissen, E.R.6
Van Der Heijden, A.7
Scheele, T.N.8
Vandenberghe, P.9
De Witte, T.10
Van Der Reijden, B.A.11
Jansen, J.H.12
-
46
-
-
84863393263
-
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
-
J.P. Patel, M. Gönen, M.E. Figueroa, H. Fernandez, Z. Sun, J. Racevskis, P. Van Vlierberghe, I. Dolgalev, S. Thomas, O. Aminova, K. Huberman, J. Cheng, A. Viale, N.D. Socci, A. Heguy, A. Cherry, G. Vance, R.R. Higgins, R.P. Ketterling, R.E. Gallagher, M. Litzow, M.R. van den Brink, H.M. Lazarus, J.M. Rowe, S. Luger, A. Ferrando, E. Paietta, M.S. Tallman, A. Melnick, O. Abdel-Wahab, R.L. Levine, Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. New Engl. J. Med. 366, 1079-1089 (2012)
-
(2012)
New Engl. J. Med
, vol.366
, pp. 1079-1089
-
-
Patel, J.P.1
Gönen, M.2
Figueroa, M.E.3
Fernandez, H.4
Sun, Z.5
Racevskis, J.6
Van Vlierberghe, P.7
Dolgalev, I.8
Thomas, S.9
Aminova, O.10
Huberman, K.11
Cheng, J.12
Viale, A.13
Socci, N.D.14
Heguy, A.15
Cherry, A.16
Vance, G.17
Higgins, R.R.18
Ketterling, R.P.19
Gallagher, R.E.20
Litzow, M.21
Van Den Brink, M.R.22
Lazarus, H.M.23
Rowe, J.M.24
Luger, S.25
Ferrando, A.26
Paietta, E.27
Tallman, M.S.28
Melnick, A.29
Abdel-Wahab, O.30
Levine, R.L.31
more..
-
47
-
-
78650019179
-
Leukemic idh1 and idh2 mutations result in a hypermethylation phenotype, disrupt tet2 function, and impair hematopoietic differentiation
-
M.E. Figueroa, O. Abdel-Wahab, C. Lu, P.S. Ward, I. Patel, A. Shih, Y. Li, N. Bhagwat, A. Vasanthakumar, H.F. Fernandez, M.S. Tallman, Z. Sun, K. Wolniak, J.K. Peeters, W. Liu, S.E. Choe, V.R. Fantin, E. Paietta, B. Löwenberg, J.D. Licht, L.A. Godley, R. Delwel, P.J. Valk, C.B. Thompson, R.L. Levine, A. Melnick, Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18, 553-567 (2010)
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, I.5
Shih, A.6
Li, Y.7
Bhagwat, N.8
Vasanthakumar, A.9
Fernandez, H.F.10
Tallman, M.S.11
Sun, Z.12
Wolniak, K.13
Peeters, J.K.14
Liu, W.15
Choe, S.E.16
Fantin, V.R.17
Paietta, E.18
Löwenberg, B.19
Licht, J.D.20
Godley, L.A.21
Delwel, R.22
Valk, P.J.23
Thompson, C.B.24
Levine, R.L.25
Melnick, A.26
more..
|