Dual-targeting of α vβ 3 and galectin-1 improves the specificity of paramagnetic/fluorescent liposomes to tumor endothelium in vivo

Journal of Controlled Release

Volumn 158, Issue 2, 2012, Pages 207-214

  Kluza, Ewelina ^a   Jacobs, Igor ^a   Hectors, Stefanie J C G ^a   Mayo, Kevin H ^b   Griffioen, Arjan W ^c   Strijkers, Gustav J ^a   Nicolay, Klaas ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UNIVERSITY OF MINNESOTA   (United States)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

v 3 integrin; Angiogenesis; Galectin 1; Liposomes; Magnetic resonance imaging; Molecular imaging

Indexed keywords

ANGIOGENESIS; BIODISTRIBUTIONS; CONTRAST AGENT; CONTRAST ENHANCEMENT; CONTRAST PARAMETER; EX-VIVO; FUNCTIONALIZED; GALECTIN-1; IN-VITRO; IN-VIVO; INTEGRINS; TUMOR TISSUES;

FLUORESCENCE MICROSCOPY; LIPOSOMES; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; MOLECULAR IMAGING; PARAMAGNETISM; PHOSPHOLIPIDS;

TUMORS;

ANGINEX; ARGINYLGLYCYLASPARTIC ACID; GALECTIN 1; LIPOSOME; NANOPARTICLE; VITRONECTIN RECEPTOR;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CONTRAST ENHANCEMENT; DRUG HALF LIFE; EX VIVO STUDY; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MELANOMA; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMA CLEARANCE; PRIORITY JOURNAL;

ANIMALS; CELL LINE, TUMOR; CONTRAST MEDIA; ENDOTHELIUM, VASCULAR; GALECTIN 1; INTEGRIN ALPHAVBETA3; LIPOSOMES; MAGNETICS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; OLIGOPEPTIDES; PEPTIDES;

EID: 84858699025     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.10.032     Document Type: Article

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