Vitamin D and drug-metabolising enzymes

Photochemical and Photobiological Sciences

Volumn 11, Issue 12, 2012, Pages 1797-1801

  Lindh, Jonatan D ^a   Björkhem Bergman, Linda ^a   Eliasson, Erik ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL RECEPTOR; CYCLOSPORIN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450 3A; DRUG; RAPAMYCIN; TACROLIMUS; VITAMIN D;

ARTICLE; BLOOD; CELL STRAIN CACO 2; DRUG DETOXIFICATION; GENETICS; HALF LIFE TIME; HUMAN; METABOLISM; ULTRAVIOLET RADIATION;

CACO-2 CELLS; CYCLOSPORINE; CYTOCHROME P-450 CYP3A; HALF-LIFE; HUMANS; METABOLIC DETOXICATION, DRUG; PHARMACEUTICAL PREPARATIONS; RECEPTORS, CALCITRIOL; SIROLIMUS; TACROLIMUS; ULTRAVIOLET RAYS; VITAMIN D;

EID: 84870012915     PISSN: 1474905X     EISSN: 14749092     Source Type: Journal    
DOI: 10.1039/c2pp25194a     Document Type: Review

References (41)

1. M. Hewison Vitamin D and immune function: an overview Proc. Nutr. Soc. 2012 71 50 61
2. M. Zasloff Fighting infections with vitamin D Nat. Med. 2006 12 388 390
3. J. H. O'Keefe C. J. Lavie M. F. Holick Vitamin D supplementation for cardiovascular disease prevention JAMA, J. Am. Med. Assoc. 2011 306 1546 1547
4. C. Buttigliero C. Monagheddu P. Petroni A. Saini L. Dogliotti G. Ciccone A. Berruti Prognostic role of vitamin D status and efficacy of vitamin D supplementation in cancer patients: a systematic review Oncologist 2011 16 1215 1227
5. J. C. Fleet M. DeSmet R. Johnson Y. Li Vitamin D and cancer: a review of molecular mechanisms Biochem. J. 2012 441 61 76
6. L. Drocourt J. C. Ourlin J. M. Pascussi P. Maurel M. J. Vilarem Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes J. Biol. Chem. 2002 277 25125 25132
7. J. Fan S. Liu Y. Du J. Morrison R. Shipman K. S. Pang Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1alpha,25- dihydroxyvitamin D3 and vitamin D analogs, in the Caco-2 cell monolayer J. Pharmacol. Exp. Ther. 2009 330 389 402
8. P. Schmiedlin-Ren K. E. Thummel J. M. Fisher M. F. Paine K. S. Lown P. B. Watkins Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3 Mol. Pharmacol. 1997 51 741 754
9. H. F. DeLuca The vitamin D story: a collaborative effort of basic science and clinical medicine FASEB J. 1988 2 224 236
10. M. F. Holick Vitamin D deficiency N. Engl. J. Med. 2007 357 266 281
11. R. Horst S. Prapong T. Reinhardt N. Koszewski J. Knutson C. Bishop Comparison of the relative effects of 1,24-dihydroxyvitamin D(2) [1,24-(OH)(2)D(2)], 1,24-dihydroxyvitamin D(3) [1,24-(OH)(2)D(3)], and 1,25-dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] on selected vitamin D-regulated events in the rat Biochem. Pharmacol. 2000 60 701 708
12. J. Ahn K. Yu R. Stolzenberg-Solomon K. C. Simon M. L. McCullough L. Gallicchio E. J. Jacobs A. Ascherio K. Helzlsouer K. B. Jacobs Q. Li S. J. Weinstein M. Purdue J. Virtamo R. Horst W. Wheeler S. Chanock D. J. Hunter R. B. Hayes P. Kraft D. Albanes Genome-wide association study of circulating vitamin D levels Hum. Mol. Genet. 2010 19 2739 2745
13. J. B. Cheng M. A. Levine N. H. Bell D. J. Mangelsdorf D. W. Russell Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase Proc. Natl. Acad. Sci. U. S. A. 2004 101 7711 7715
14. D. E. Prosser G. Jones Enzymes involved in the activation and inactivation of vitamin D Trends Biochem. Sci. 2004 29 664 673
15. C. Carlberg I. Bendik A. Wyss E. Meier L. J. Sturzenbecker J. F. Grippo W. Hunziker Two nuclear signalling pathways for vitamin D Nature 1993 361 657 660
16. C. Carlberg S. Seuter A genomic perspective on vitamin D signaling Anticancer Res. 2009 29 3485 3493
17. T. T. Wang L. E. Tavera-Mendoza D. Laperriere E. Libby N. B. MacLeod Y. Nagai V. Bourdeau A. Konstorum B. Lallemant R. Zhang S. Mader J. H. White Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes Mol. Endocrinol. 2005 19 2685 2695
18. Z. Wang Y. S. Lin X. E. Zheng T. Senn T. Hashizume M. Scian L. J. Dickmann S. D. Nelson T. A. Baillie M. F. Hebert D. Blough C. L. Davis K. E. Thummel An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway Mol. Pharmacol. 2012 81 498 509
19. T. Hashizume Y. Xu M. A. Mohutsky J. Alberts C. Hadden T. F. Kalhorn N. Isoherranen M. C. Shuhart K. E. Thummel Identification of human UDP-glucuronosyltransferases catalyzing hepatic 1alpha,25-dihydroxyvitamin D3 conjugation Biochem. Pharmacol. 2008 75 1240 1250
20. K. T. Kivisto G. Bookjans M. F. Fromm E. U. Griese P. Munzel H. K. Kroemer Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue Br. J. Clin. Pharmacol. 1996 42 387 389
21. J. C. Kolars P. Schmiedlin-Ren J. D. Schuetz C. Fang P. B. Watkins Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes J. Clin. Invest. 1992 90 1871 1878
22. M. F. Paine D. D. Shen K. L. Kunze J. D. Perkins C. L. Marsh J. P. McVicar D. M. Barr B. S. Gillies K. E. Thummel First-pass metabolism of midazolam by the human intestine Clin. Pharmacol. Ther. (St. Louis) 1996 60 14 24
23. A. K. Daly Significance of the minor cytochrome P450 3A isoforms Clin. Pharmacokinet. 2006 45 13 31
24. M. F. Paine M. Khalighi J. M. Fisher D. D. Shen K. L. Kunze C. L. Marsh J. D. Perkins K. E. Thummel Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism J. Pharmacol. Exp. Ther. 1997 283 1552 1562
25. O. von Richter O. Burk M. F. Fromm K. P. Thon M. Eichelbaum K. T. Kivisto Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens Clin. Pharmacol. Ther. 2004 75 172 183
26. K. E. Thummel C. Brimer K. Yasuda J. Thottassery T. Senn Y. Lin H. Ishizuka E. Kharasch J. Schuetz E. Schuetz Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3 Mol. Pharmacol. 2001 60 1399 1406
27. P. Pavek K. Pospechova L. Svecova Z. Syrova L. Stejskalova J. Blazkova Z. Dvorak J. Blahos Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene Biochem. Pharmacol. 2010 79 277 287
28. P. D. Thompson P. W. Jurutka G. K. Whitfield S. M. Myskowski K. R. Eichhorst C. E. Dominguez C. A. Haussler M. R. Haussler Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements Biochem. Biophys. Res. Commun. 2002 299 730 738
29. A. R. Webb L. Kline M. F. Holick Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin J. Clin. Endocrinol. Metab. 1988 67 373 378
30. J. D. Lindh M. L. Andersson E. Eliasson L. Bjorkhem-Bergman Seasonal variation in blood drug concentrations and a potential relationship to vitamin D Drug Metab. Dispos.: Biolog. Fate Chem. 2011 39 933 937
31. J. K. Virtanen T. Nurmi S. Voutilainen J. Mursu T. P. Tuomainen Association of serum 25-hydroxyvitamin D with the risk of death in a general older population in Finland Eur. J. Nutr. 2011 50 305 312
32. R. K. Thirumaran J. K. Lamba R. B. Kim B. L. Urquhart J. C. Gregor N. Chande Y. Fan A. Qi C. Cheng K. E. Thummel S. D. Hall E. G. Schuetz Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation Biochem. Pharmacol. 2012 84 104 112
33. T. Kantola K. T. Kivisto P. J. Neuvonen Effect of itraconazole on the pharmacokinetics of atorvastatin Clin. Pharmacol. Ther. 1998 64 58 65
34. J. B. Schwartz Effects of vitamin D supplementation in atorvastatin-treated patients: a new drug interaction with an unexpected consequence Clin. Pharmacol. Ther. 2009 85 198 203
35. M. Karlgren A. Vildhede U. Norinder J. R. Wisniewski E. Kimoto Y. Lai U. Haglund P. Artursson Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions J. Med. Chem. 2012 55 4740 4763
36. J. J. Eloranta C. Hiller M. Juttner G. A. Kullak-Ublick The SLCO1A2 gene, encoding the human organic anion transporting polypeptide 1A2 (OATP1A2), is transactivated by the vitamin D receptor (VDR) Mol. Pharmacol. 2012 82 37 46
37. R. Persson A. H. Garde A. M. Hansen K. Osterberg B. Larsson P. Orbaek B. Karlson Seasonal variation in human salivary cortisol concentration Chronobiol. Int. 2008 25 923 937
38. K. Bodin U. Lindbom U. Diczfalusy Novel pathways of bile acid metabolism involving CYP3A4 Biochim. Biophys. Acta 2005 1687 84 93
39. B. Berg G. Helm L. Petersohn N. Tryding Cholestasis of pregnancy. Clinical and laboratory studies Acta Obstetr. Gynecol. Scand. 1986 65 107 113
40. E. Wikstrom Shemer H. U. Marschall Decreased 1,25-dihydroxy vitamin D levels in women with intrahepatic cholestasis of pregnancy Acta Obstetr. Gynecol. Scand. 2010 89 1420 1423
41. M. K. DeGorter C. Q. Xia J. J. Yang R. B. Kim Drug transporters in drug efficacy and toxicity Annu. Rev. Pharmacol. Toxicol. 2012 52 249 273