메뉴 건너뛰기




Volumn 23, Issue 6, 2012, Pages 532-539

Novel anti-inflammatory strategies in atherosclerosis

Author keywords

anti inflammatory strategies; atherosclerosis; cardiovascular imaging; vessel wall inflammation

Indexed keywords

ADALIMUMAB; ATRELEUTON; C REACTIVE PROTEIN; CANAKINUMAB; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR2 ANTAGONIST; DARAPLADIB; FIBRINOGEN; INFLIXIMAB; INTERLEUKIN 6; METHOTREXATE; MLN 1202; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TOCILIZUMAB; UNCLASSIFIED DRUG; VARESPLADIB; VASCULAR CELL ADHESION MOLECULE 1; VELIFLAPON;

EID: 84870004060     PISSN: 09579672     EISSN: 14736535     Source Type: Journal    
DOI: 10.1097/MOL.0b013e3283587543     Document Type: Review
Times cited : (46)

References (92)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 2
    • 79956319051 scopus 로고    scopus 로고
    • Progress and challenges in translating the biology of atherosclerosis
    • This is a detailed review on the inflammatory hypothesis of atherogenesis and the need for extrapolation to humans
    • Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature 2011; 473:317-325. This is a detailed review on the inflammatory hypothesis of atherogenesis and the need for extrapolation to humans.
    • (2011) Nature , vol.473 , pp. 317-325
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 3
    • 84856970805 scopus 로고    scopus 로고
    • The ins and outs of inflammatory cells in atheromata
    • Swirski FK, Nahrendorf M, Libby P. The ins and outs of inflammatory cells in atheromata. Cell Metab 2012; 15:135-136.
    • (2012) Cell Metab , vol.15 , pp. 135-136
    • Swirski, F.K.1    Nahrendorf, M.2    Libby, P.3
  • 5
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
    • Gu L, Okada Y, Clinton SK, et al. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell 1998; 2:275-281. (Pubitemid 128373654)
    • (1998) Molecular Cell , vol.2 , Issue.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3    Gerard, C.4    Sukhova, G.K.5    Libby, P.6    Rollins, B.J.7
  • 6
    • 0032572719 scopus 로고    scopus 로고
    • Decreased lesion formation in CCR2(-/-) mice reveals a role for chemokines in the initiation of atherosclerosis
    • DOI 10.1038/29788
    • Boring L, Gosling J, Cleary M, Charo IF. Decreased lesion formation in CCR2/mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998; 394:894-897. (Pubitemid 28410911)
    • (1998) Nature , vol.394 , Issue.6696 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 7
    • 0035076642 scopus 로고    scopus 로고
    • Involvement of chemokine receptor 2 and its ligand, monocyte chemoattractant protein-1, in the development of atherosclerosis: Lessons from knockout mice
    • DOI 10.1097/00041433-200104000-00011
    • Peters W, Charo IF. Involvement of chemokine receptor 2 and its ligand, monocyte chemoattractant protein-1, in the development of atherosclerosis: lessons from knockout mice. Curr Opin Lipidol 2001; 12:175-180. (Pubitemid 32242925)
    • (2001) Current Opinion in Lipidology , vol.12 , Issue.2 , pp. 175-180
    • Peters, W.1    Charo, I.F.2
  • 10
    • 0037421497 scopus 로고    scopus 로고
    • Vascular biology of atherosclerosis: Overview and state of the art
    • DOI 10.1016/S0002-9149(02)03143-0, PII S0002914902031430
    • Libby P. Vascular biology of atherosclerosis: overview and state of the art. Am J Cardiol 2003; 91:3A-6.A. (Pubitemid 36351456)
    • (2003) American Journal of Cardiology , vol.91 , Issue.3 SUPPL.
    • Libby, P.1
  • 11
    • 84862907755 scopus 로고    scopus 로고
    • Biomarkers and cardiovascular risk assessment for primary prevention: An update
    • Gilstrap LG, Wang TJ. Biomarkers and cardiovascular risk assessment for primary prevention: an update. Clin Chem 2012; 58:72-82.
    • (2012) Clin Chem , vol.58 , pp. 72-82
    • Gilstrap, L.G.1    Wang, T.J.2
  • 12
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated c-reactive protein
    • Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008; 359:2195-2207.
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 14
    • 84880230242 scopus 로고    scopus 로고
    • Association between c reactive protein and coronary heart disease: Mendelian randomisation analysis based on individual participant data
    • Wensley F, Gao P, Burgess S, et al. Association between C reactive protein and coronary heart disease: Mendelian randomisation analysis based on individual participant data. Br Med J 2011; 342:d548.
    • (2011) Br Med J , vol.342
    • Wensley, F.1    Gao, P.2    Burgess, S.3
  • 15
    • 43249118045 scopus 로고    scopus 로고
    • Long-term interleukin-6 levels and subsequent risk of coronary heart disease: Two new prospective studies and a systematic review
    • Danesh J, Kaptoge S, Mann AG, et al. Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review. PLoS Med 2008; 5:600-610.
    • (2008) PLoS Med , vol.5 , pp. 600-610
    • Danesh, J.1    Kaptoge, S.2    Mann, A.G.3
  • 16
    • 0034681920 scopus 로고    scopus 로고
    • Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men
    • Ridker PM, Rifai N, Stampfer MJ, Hennekens CH. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 2000; 101:1767-1772. (Pubitemid 30213096)
    • (2000) Circulation , vol.101 , Issue.15 , pp. 1767-1772
    • Ridker, P.M.1    Rifai, N.2    Stampfer, M.J.3    Hennekens, C.H.4
  • 17
    • 84859210770 scopus 로고    scopus 로고
    • Interleukin-6 receptor pathways in coronary heart disease: A collaborative meta-analysis of 82 studies
    • This study provides solid evidence for a causal role of the pro-inflammatory IL-6 pathway in determining risk of coronary heart disease
    • Sarwar N, Butterworth AS, Freitag DF, et al. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 2012; 379:1205-1213. This study provides solid evidence for a causal role of the pro-inflammatory IL-6 pathway in determining risk of coronary heart disease.
    • (2012) Lancet , vol.379 , pp. 1205-1213
    • Sarwar, N.1    Butterworth, A.S.2    Freitag, D.F.3
  • 18
    • 84859215358 scopus 로고    scopus 로고
    • The interleukin-6 receptor as a target for prevention of coronary heart disease: A mendelian randomisation analysis
    • This article provides strong grounds for IL6R to have a causal role in development of coronary heart disease
    • Hingorani AD, Casas JP. The interleukin-6 receptor as a target for prevention of coronary heart disease: a Mendelian randomisation analysis. Lancet 2012; 379:1214-1224. This article provides strong grounds for IL6R to have a causal role in development of coronary heart disease.
    • (2012) Lancet , vol.379 , pp. 1214-1224
    • Hingorani, A.D.1    Casas, J.P.2
  • 22
    • 0346365086 scopus 로고    scopus 로고
    • Explaining How "High-Grade" Systemic Inflammation Accelerates Vascular Risk in Rheumatoid Arthritis
    • DOI 10.1161/01.CIR.0000099844.31524.05
    • Sattar N, McCarey DW, Capell H, McInnes IB. Explaining how 'high-grade' systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation 2003; 108:2957-2963. (Pubitemid 37553561)
    • (2003) Circulation , vol.108 , Issue.24 , pp. 2957-2963
    • Sattar, N.1    McCarey, D.W.2    Capell, H.3    McInnes, I.B.4
  • 23
    • 0039855369 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in patients with seropositive rheumatoid arthritis in Northern Sweden
    • Wallberg-Jonsson S, Ohman ML, Dahlqvist SR. Cardiovascular morbidity and mortality in patients with seropositive rheumatoid arthritis in Northern Sweden. J Rheumatol 1997; 24:445-451. (Pubitemid 27153406)
    • (1997) Journal of Rheumatology , vol.24 , Issue.3 , pp. 445-451
    • Wallberg-Jonsson, S.1    Ohman, M.-L.2    Dahlqvist, S.R.3
  • 25
    • 84857232987 scopus 로고    scopus 로고
    • Mycophenolate mofetil but not atorvastatin attenuates atherosclerosis in lupus-prone ldlr(/) mice
    • van Leuven SI, Mendez-Fernandez YV, Wilhelm AJ, et al. Mycophenolate mofetil but not atorvastatin attenuates atherosclerosis in lupus-prone LDLr(/) mice. Ann Rheum Dis 2012; 71:408-414.
    • (2012) Ann Rheum Dis , vol.71 , pp. 408-414
    • Van Leuven, S.I.1    Mendez-Fernandez, Y.V.2    Wilhelm, A.J.3
  • 26
    • 0037133346 scopus 로고    scopus 로고
    • Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model
    • DOI 10.1161/hc0702.104178
    • Li L, Messas E, Batista EL Jr., et al. Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model. Circulation 2002; 105:861-867. (Pubitemid 34174928)
    • (2002) Circulation , vol.105 , Issue.7 , pp. 861-867
    • Li, L.1    Messas, E.2    Batista Jr., E.L.3    Levine, R.A.4    Amar, S.5
  • 28
    • 0033844504 scopus 로고    scopus 로고
    • Herpesvirus infection accelerates atherosclerosis in the apolipoprotein E-deficient mouse
    • Alber DG, Powell KL, Vallance P, et al. Herpesvirus infection accelerates atherosclerosis in the apolipoprotein E-deficient mouse. Circulation 2000; 102:779-785. (Pubitemid 30648767)
    • (2000) Circulation , vol.102 , Issue.7 , pp. 779-785
    • Alber, D.G.1    Powell, K.L.2    Vallance, P.3    Goodwin, D.A.4    Grahame-Clarke, C.5
  • 29
    • 34247564814 scopus 로고    scopus 로고
    • Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: A case control study
    • van Halm VP, Nurmohamed MT, Twisk JW, et al. Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study. Arthritis Res Ther 2006; 8:R151.
    • (2006) Arthritis Res Ther , vol.8
    • Van Halm, V.P.1    Nurmohamed, M.T.2    Twisk, J.W.3
  • 30
    • 80054698399 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of methotrexate use and risk of cardiovascular disease
    • Micha R, Imamura F, Wyler von BM, et al. Systematic review and meta-analysis of methotrexate use and risk of cardiovascular disease. Am J Cardiol 2011; 108:1362-1370.
    • (2011) Am J Cardiol , vol.108 , pp. 1362-1370
    • Micha, R.1    Imamura, F.2    Wyler Von, B.M.3
  • 31
    • 48749110858 scopus 로고    scopus 로고
    • Cytokines and atherosclerosis: A comprehensive review of studies in mice
    • Kleemann R, Zadelaar S, Kooistra T. Cytokines and atherosclerosis: a comprehensive review of studies in mice. Cardiovasc Res 2008; 79:360-376.
    • (2008) Cardiovasc Res , vol.79 , pp. 360-376
    • Kleemann, R.1    Zadelaar, S.2    Kooistra, T.3
  • 33
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A double-edged sword
    • DOI 10.1038/nri1882, PII N1882
    • Hansson GK, Libby P. The immune response in atherosclerosis: a doubleedged sword. Nat Rev Immunol 2006; 6:508-519. (Pubitemid 43980523)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.7 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 34
    • 2942720515 scopus 로고    scopus 로고
    • Beneficial cardiovascular pleiotropic effects of statins
    • Davignon J. Beneficial cardiovascular pleiotropic effects of statins. Circulation 2004; 109 (23 SUPPL. 1):III39-III43. (Pubitemid 38786442)
    • (2004) Circulation , vol.109 , Issue.23 SUPPL.
    • Davignon, J.1
  • 35
    • 0035895319 scopus 로고    scopus 로고
    • An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro
    • Aikawa M, Rabkin E, Sugiyama S, et al. An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation 2001; 103:276-283. (Pubitemid 32095415)
    • (2001) Circulation , vol.103 , Issue.2 , pp. 276-283
    • Aikawa, M.1    Rabkin, E.2    Sugiyama, S.3    Voglic, S.J.4    Fukumoto, Y.5    Furukawa, Y.6    Shiomi, M.7    Schoen, F.J.8    Libby, P.9
  • 36
    • 3042638413 scopus 로고    scopus 로고
    • Simvastatin modulates TNFα-induced adhesion molecules expression in human endothelial cells
    • DOI 10.1016/j.lfs.2004.03.005, PII S0024320504004163
    • Zapolska-Downar D, Siennicka A, Kaczmarczyk M, et al. Simvastatin modulates TNFalpha-induced adhesion molecules expression in human endothelial cells. Life Sci 2004; 75:1287-1302. (Pubitemid 38845028)
    • (2004) Life Sciences , vol.75 , Issue.11 , pp. 1287-1302
    • Zapolska-Downar, D.1    Siennicka, A.2    Kaczmarczyk, M.3    Kolodziej, B.4    Naruszewicz, M.5
  • 37
    • 77955711541 scopus 로고    scopus 로고
    • Relation of baseline highsensitivity c-reactive protein level to cardiovascular outcomes with rosuvastatin in the justification for use of statins in prevention: An intervention trial evaluating rosuvastatin (jupiter
    • Ridker PM, MacFadyen J, Libby P, Glynn RJ. Relation of baseline highsensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER). Am J Cardiol 2010; 106:204-209.
    • (2010) Am J Cardiol , vol.106 , pp. 204-209
    • Ridker, P.M.1    MacFadyen, J.2    Libby, P.3    Glynn, R.J.4
  • 38
    • 2942670131 scopus 로고    scopus 로고
    • Trial of Atorvastatin in Rheumatoid Arthritis (TARA): Double-blind, randomised placebo-controlled trial
    • DOI 10.1016/S0140-6736(04)16449-0, PII S0140673604164490
    • McCarey DW, McInnes IB, Madhok R, et al. Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial. Lancet 2004; 363:2015-2021. (Pubitemid 38781100)
    • (2004) Lancet , vol.363 , Issue.9426 , pp. 2015-2021
    • McCarey, D.W.1    McInnes, I.B.2    Madhok, R.3    Hampson, R.4    Scherbakov, O.5    Ford, I.6    Capell, H.A.7    Sattar, N.8
  • 39
    • 27644544308 scopus 로고    scopus 로고
    • Pleiotropic effects of statins: Benefit beyond cholesterol reduction?: A meta-regression analysis
    • DOI 10.1016/j.jacc.2005.05.085, PII S0735109705017699
    • Robinson JG, Smith B, Maheshwari N, Schrott H. Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis. J Am Coll Cardiol 2005; 46:1855-1862. (Pubitemid 41579807)
    • (2005) Journal of the American College of Cardiology , vol.46 , Issue.10 , pp. 1855-1862
    • Robinson, J.G.1    Smith, B.2    Maheshwari, N.3    Schrott, H.4
  • 40
    • 84863789387 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein (cetp) inhibition as a strategy to reduce cardiovascular risk
    • Barter PJ, Rye KA. Cholesteryl ester transfer protein (CETP) inhibition as a strategy to reduce cardiovascular risk. J Lipid Res 2012; 53:1755-1766.
    • (2012) J Lipid Res , vol.53 , pp. 1755-1766
    • Barter, P.J.1    Rye, K.A.2
  • 42
    • 80255122648 scopus 로고    scopus 로고
    • Safety and efficacy of dalcetrapib on atherosclerotic disease using novel noninvasive multimodality imaging (dal-plaque): A randomised clinical trial
    • Fayad ZA, Mani V, Woodward M, et al. Safety and efficacy of dalcetrapib on atherosclerotic disease using novel noninvasive multimodality imaging (dal-PLAQUE): a randomised clinical trial. Lancet 2011; 378:1547-1559.
    • (2011) Lancet , vol.378 , pp. 1547-1559
    • Fayad, Z.A.1    Mani, V.2    Woodward, M.3
  • 45
    • 84859495141 scopus 로고    scopus 로고
    • Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2011
    • Furst DE, Keystone EC, Braun J, et al. Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2011. Ann Rheum Dis 2012; 71 (SUPPL. 2):i2-i45.
    • (2012) Ann Rheum Dis , vol.71 , Issue.SUPPL. 2
    • Furst, D.E.1    Keystone, E.C.2    Braun, J.3
  • 46
    • 77954314887 scopus 로고    scopus 로고
    • Mycophenolate mofetil attenuates plaque inflammation in patients with symptomatic carotid artery stenosis
    • van Leuven SI, van Wijk DF, Volger OL, et al. Mycophenolate mofetil attenuates plaque inflammation in patients with symptomatic carotid artery stenosis. Atherosclerosis 2010; 211:231-236.
    • (2010) Atherosclerosis , vol.211 , pp. 231-236
    • Van Leuven, S.I.1    Van Wijk, D.F.2    Volger, O.L.3
  • 47
    • 0037029418 scopus 로고    scopus 로고
    • Methotrexate and mortality in patients with rheumatoid arthritis: A prospective study
    • DOI 10.1016/S0140-6736(02)08213-2
    • Choi HK, Hernan MA, Seeger JD, et al. Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study. Lancet 2002; 359:1173-1177. (Pubitemid 34304256)
    • (2002) Lancet , vol.359 , Issue.9313 , pp. 1173-1177
    • Choi, H.K.1    Hernan, M.A.2    Seeger, J.D.3    Robins, J.M.4    Wolfe, F.5
  • 48
    • 67949124665 scopus 로고    scopus 로고
    • Testing the inflammatory hypothesis of atherothrombosis: Scientific rationale for the cardiovascular inflammation reduction trial (cirt
    • Ridker PM. Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT). J Thromb Haemost 2009; 7 (SUPPL. 1):332-339.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 332-339
    • Ridker, P.M.1
  • 49
    • 78649477259 scopus 로고    scopus 로고
    • Tnf-alpha antagonists beyond approved indications: Stories of success and prospects for the future
    • Karampetsou MP, Liossis SN, Sfikakis PP. TNF-alpha antagonists beyond approved indications: stories of success and prospects for the future. QJM 2010; 103:917-928.
    • (2010) QJM , vol.103 , pp. 917-928
    • Karampetsou, M.P.1    Liossis, S.N.2    Sfikakis, P.P.3
  • 50
    • 0038755661 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe heart failure: Results of the anti-TNF therapy against congestive heart failure (ATTACH) trial
    • DOI 10.1161/01.CIR.0000077913.60364.D2
    • Chung ES, Packer M, Lo KH, et al. Randomized, double-blind, placebocontrolled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation 2003; 107:3133-3140. (Pubitemid 36793081)
    • (2003) Circulation , vol.107 , Issue.25 , pp. 3133-3140
    • Chung, E.S.1    Packer, M.2    Lo, K.H.3    Fasanmade, A.A.4    Willerson, J.T.5
  • 52
    • 33747132177 scopus 로고    scopus 로고
    • Vascular biomarkers and surrogates in cardiovascular disease
    • DOI 10.1161/CIRCULATIONAHA.105.598987, PII 0000301720060627000014
    • Tardif JC, Heinonen T, Orloff D, Libby P. Vascular biomarkers and surrogates in cardiovascular disease. Circulation 2006; 113:2936-2942. (Pubitemid 44297235)
    • (2006) Circulation , vol.113 , Issue.25 , pp. 2936-2942
    • Tardif, J.-C.1    Heinonen, T.2    Orloff, D.3    Libby, P.4
  • 54
    • 84861811411 scopus 로고    scopus 로고
    • Noninvasive anatomic and functional imaging of vascular inflammation and unstable plaque
    • Camici PG, Rimoldi OE, Gaemperli O, Libby P. Noninvasive anatomic and functional imaging of vascular inflammation and unstable plaque. Eur Heart J 2012; 33:1309-1317.
    • (2012) Eur Heart J , vol.33 , pp. 1309-1317
    • Camici, P.G.1    Rimoldi, O.E.2    Gaemperli, O.3    Libby, P.4
  • 55
    • 66449136292 scopus 로고    scopus 로고
    • Comparison of in vivo carotid 3.0-t magnetic resonance to b-mode ultrasound imaging and histology in a porcine model
    • Duivenvoorden R, de GE, Afzali H, et al. Comparison of in vivo carotid 3.0-T magnetic resonance to B-mode ultrasound imaging and histology in a porcine model. JACC Cardiovasc Imaging 2009; 2:744-750.
    • (2009) JACC Cardiovasc Imaging , vol.2 , pp. 744-750
    • Duivenvoorden, R.1    De, G.E.2    Afzali, H.3
  • 56
    • 70350480977 scopus 로고    scopus 로고
    • In vivo quantification of carotid artery wall dimensions: 3.0-tesla mri versus b-mode ultrasound imaging
    • Duivenvoorden R, de GE, Elsen BM, et al. In vivo quantification of carotid artery wall dimensions: 3.0-Tesla MRI versus B-mode ultrasound imaging. Circ Cardiovasc Imaging 2009; 2:235-242.
    • (2009) Circ Cardiovasc Imaging , vol.2 , pp. 235-242
    • Duivenvoorden, R.1    De, G.E.2    Elsen, B.M.3
  • 57
    • 74049135291 scopus 로고    scopus 로고
    • Scan-rescan reproducibility of carotid atherosclerotic plaque morphology and tissue composition measurements using multicontrast mri at 3t
    • Li F, Yarnykh VL, Hatsukami TS, et al. Scan-rescan reproducibility of carotid atherosclerotic plaque morphology and tissue composition measurements using multicontrast MRI at 3T. J Magn Reson Imaging 2010; 31:168-176.
    • (2010) J Magn Reson Imaging , vol.31 , pp. 168-176
    • Li, F.1    Yarnykh, V.L.2    Hatsukami, T.S.3
  • 58
    • 77955665380 scopus 로고    scopus 로고
    • Dynamic contrast enhanced (dce) magnetic resonance imaging (mri) of atherosclerotic plaque angiogenesis
    • Calcagno C, Mani V, Ramachandran S, Fayad ZA. Dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) of atherosclerotic plaque angiogenesis. Angiogenesis 2010; 13:87-99.
    • (2010) Angiogenesis , vol.13 , pp. 87-99
    • Calcagno, C.1    Mani, V.2    Ramachandran, S.3    Fayad, Z.A.4
  • 59
    • 33745700345 scopus 로고    scopus 로고
    • Intra-and interreader reproducibility of magnetic resonance imaging for quantifying the lipid-rich necrotic core is improved with gadolinium contrast enhancement
    • Takaya N, Cai J, Ferguson MS, et al. Intra-and interreader reproducibility of magnetic resonance imaging for quantifying the lipid-rich necrotic core is improved with gadolinium contrast enhancement. J Magn Reson Imaging 2006; 24:203-210.
    • (2006) J Magn Reson Imaging , vol.24 , pp. 203-210
    • Takaya, N.1    Cai, J.2    Ferguson, M.S.3
  • 60
    • 0028925793 scopus 로고
    • Intimal neovascularization in human coronary atherosclerosis: Its origin and pathophysiological significance
    • Kumamoto M, Nakashima Y, Sueishi K. Intimal neovascularization in human coronary atherosclerosis: its origin and pathophysiological significance. Hum Pathol 1995; 26:450-456.
    • (1995) Hum Pathol , vol.26 , pp. 450-456
    • Kumamoto, M.1    Nakashima, Y.2    Sueishi, K.3
  • 63
    • 77951079412 scopus 로고    scopus 로고
    • Gene expression and 18fdg uptake in atherosclerotic carotid plaques
    • Pedersen SF, Graebe M, Fisker Hag AM, et al. Gene expression and 18FDG uptake in atherosclerotic carotid plaques. Nucl Med Commun 2010; 31:423-429.
    • (2010) Nucl Med Commun , vol.31 , pp. 423-429
    • Pedersen, S.F.1    Graebe, M.2    Fisker Hag, A.M.3
  • 64
    • 84860216687 scopus 로고    scopus 로고
    • Carotid plaque inflammation on (18) f-fluorodeoxyglucose positron emission tomography predicts early stroke recurrence
    • Marnane M, Merwick A, Sheehan OC, et al. Carotid plaque inflammation on (18) F-fluorodeoxyglucose positron emission tomography predicts early stroke recurrence. Ann Neurol 2012; 71:709-718.
    • (2012) Ann Neurol , vol.71 , pp. 709-718
    • Marnane, M.1    Merwick, A.2    Sheehan, O.C.3
  • 65
    • 44449136941 scopus 로고    scopus 로고
    • Form to function: Current and future roles for atherosclerosis imaging in drug development
    • DOI 10.1038/nrd2588, PII NRD2588
    • Lindsay AC, Choudhury RP. Form to function: current and future roles for atherosclerosis imaging in drug development. Nat Rev Drug Discov 2008; 7:517-529. (Pubitemid 351767119)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.6 , pp. 517-529
    • Lindsay, A.C.1    Choudhury, R.P.2
  • 67
    • 84863459500 scopus 로고    scopus 로고
    • Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events
    • Abbate A, Van Tassell BW, Biondi-Zoccai GG. Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events. BioDrugs 2012; 26:217-233.
    • (2012) BioDrugs , vol.26 , pp. 217-233
    • Abbate, A.1    Van Tassell, B.W.2    Biondi-Zoccai, G.G.3
  • 69
    • 0033666905 scopus 로고    scopus 로고
    • Protective role against restenosis from an interleukin-1 receptor antagonist gene polymorphism in patients treated with coronary stenting
    • Kastrati A, Koch W, Berger PB, et al. Protective role against restenosis from an interleukin-1 receptor antagonist gene polymorphism in patients treated with coronary stenting. J Am Coll Cardiol 2000; 36:2168-2173.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 2168-2173
    • Kastrati, A.1    Koch, W.2    Berger, P.B.3
  • 70
    • 80053644777 scopus 로고    scopus 로고
    • Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: Rationale and design of the canakinumab anti-inflammatory thrombosis outcomes study (cantos
    • Ridker PM, Thuren T, Zalewski A, Libby P. Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS). Am Heart J 2011; 162:597-605.
    • (2011) Am Heart J , vol.162 , pp. 597-605
    • Ridker, P.M.1    Thuren, T.2    Zalewski, A.3    Libby, P.4
  • 71
    • 42349111723 scopus 로고    scopus 로고
    • Investigation of the effect of interleukin-1 receptor antagonist (il-1ra) on markers of inflammation in non-st elevation acute coronary syndromes (the mrc-ila-heart study
    • Crossman DC, Morton AC, Gunn JP, et al. Investigation of the effect of Interleukin-1 receptor antagonist (IL-1ra) on markers of inflammation in non-ST elevation acute coronary syndromes (The MRC-ILA-HEART Study). Trials 2008; 9:8.
    • (2008) Trials , vol.9 , pp. 8
    • Crossman, D.C.1    Morton, A.C.2    Gunn, J.P.3
  • 72
    • 84894320388 scopus 로고    scopus 로고
    • A review of tocilizumab treatment in 122 rheumatoid arthritis patients included in the tsurumai biologics communication registry (tbcr) study
    • [Epub ahead of print]
    • Yabe Y, Kojima T, Kaneko A, et al. A review of tocilizumab treatment in 122 rheumatoid arthritis patients included in the Tsurumai Biologics Communication Registry (TBCR) Study. Mod Rheumatol 2012 [Epub ahead of print].
    • (2012) Mod Rheumatol
    • Yabe, Y.1    Kojima, T.2    Kaneko, A.3
  • 73
    • 84859218984 scopus 로고    scopus 로고
    • The interleukin-6 pathway and atherosclerosis
    • Boekholdt SM, Stroes ES. The interleukin-6 pathway and atherosclerosis. Lancet 2012; 379:1176-1178.
    • (2012) Lancet , vol.379 , pp. 1176-1178
    • Boekholdt, S.M.1    Stroes, E.S.2
  • 74
    • 79952316203 scopus 로고    scopus 로고
    • Effect of cc chemokine receptor 2 ccr2 blockade on serum c-reactive protein in individuals at atherosclerotic risk and with a single nucleotide polymorphism of the monocyte chemoattractant protein-1 promoter region
    • Gilbert J, Lekstrom-Himes J, Donaldson D, et al. Effect of CC chemokine receptor 2 CCR2 blockade on serum C-reactive protein in individuals at atherosclerotic risk and with a single nucleotide polymorphism of the monocyte chemoattractant protein-1 promoter region. Am J Cardiol 2011; 107:906-911.
    • (2011) Am J Cardiol , vol.107 , pp. 906-911
    • Gilbert, J.1    Lekstrom-Himes, J.2    Donaldson, D.3
  • 75
    • 60249083241 scopus 로고    scopus 로고
    • Phospholipase a2 inhibitors in atherosclerosis: The race is on
    • Corson MA. Phospholipase A2 inhibitors in atherosclerosis: the race is on. Lancet 2009; 373:608-610.
    • (2009) Lancet , vol.373 , pp. 608-610
    • Corson, M.A.1
  • 76
    • 77951605907 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase a(2) and risk of coronary disease, stroke, and mortality: Collaborative analysis of 32 prospective studies
    • Thompson A, Gao P, Orfei L, et al. Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet 2010; 375:1536-1544.
    • (2010) Lancet , vol.375 , pp. 1536-1544
    • Thompson, A.1    Gao, P.2    Orfei, L.3
  • 78
    • 60249101701 scopus 로고    scopus 로고
    • Effects of 1-h-indole-3-glyoxamide (a-002) on concentration of secretory phospholipase a2 (plasma study): A phase ii double-blind, randomised, placebo-controlled trial
    • Rosenson RS, Hislop C, McConnell D, et al. Effects of 1-H-indole-3-glyoxamide (A-002) on concentration of secretory phospholipase A2 (PLASMA study): a phase II double-blind, randomised, placebo-controlled trial. Lancet 2009; 373:649-658.
    • (2009) Lancet , vol.373 , pp. 649-658
    • Rosenson, R.S.1    Hislop, C.2    McConnell, D.3
  • 79
    • 84857792744 scopus 로고    scopus 로고
    • Inhibition of secretory phospholipase a(2) in patients with acute coronary syndromes: Rationale and design of the vascular inflammation suppression to treat acute coronary syndrome for 16 weeks (vista-16) trial
    • Nicholls SJ, Cavender MA, Kastelein JJ, et al. Inhibition of secretory phospholipase A(2) in patients with acute coronary syndromes: rationale and design of the vascular inflammation suppression to treat acute coronary syndrome for 16 weeks (VISTA-16) trial. Cardiovasc Drugs Ther 2012; 26:71-75.
    • (2012) Cardiovasc Drugs Ther , vol.26 , pp. 71-75
    • Nicholls, S.J.1    Cavender, M.A.2    Kastelein, J.J.3
  • 80
    • 84871220999 scopus 로고    scopus 로고
    • Anthera Pharmaceuticals.
    • Anthera Pharmaceuticals. http://investor.anthera.com/releases.cfm. 2012.
    • (2012)
  • 81
    • 43049122963 scopus 로고    scopus 로고
    • 2 Activity and Cardiovascular Biomarkers in Patients With Stable Coronary Heart Disease or Coronary Heart Disease Risk Equivalent. The Results of a Multicenter, Randomized, Double-Blind, Placebo-Controlled Study
    • DOI 10.1016/j.jacc.2007.11.079, PII S073510970800569X
    • Mohler ER III, Ballantyne CM, Davidson MH, et al. The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study. J Am Coll Cardiol 2008; 51:1632-1641. (Pubitemid 351635837)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.17 , pp. 1632-1641
    • Mohler III, E.R.1    Ballantyne, C.M.2    Davidson, M.H.3    Hanefeld, M.4    Ruilope, L.M.5    Johnson, J.L.6    Zalewski, A.7
  • 82
    • 84880282303 scopus 로고    scopus 로고
    • Secondary prevention and risk factor target achievement in a global, high-risk population with established coronary heart disease: Baseline results from the stability study
    • [Epub ahead of print]
    • Vedin O, Hagstrom E, Stewart R, et al. Secondary prevention and risk factor target achievement in a global, high-risk population with established coronary heart disease: baseline results from the STABILITY study. Eur J Prev Cardiol 2012 [Epub ahead of print].
    • (2012) Eur J Prev Cardiol
    • Vedin, O.1    Hagstrom, E.2    Stewart, R.3
  • 83
    • 80053647826 scopus 로고    scopus 로고
    • Study design and rationale for the stabilization of plaques using darapladib-thrombolysis in myocardial infarction (solid-timi 52) trial in patients after an acute coronary syndrome
    • O'Donoghue ML, Braunwald E, White HD, et al. Study design and rationale for the Stabilization of pLaques usIng Darapladib-Thrombolysis in Myocardial Infarction (SOLID-TIMI 52) trial in patients after an acute coronary syndrome. Am Heart J 2011; 162:613-619.
    • (2011) Am Heart J , vol.162 , pp. 613-619
    • O'Donoghue, M.L.1    Braunwald, E.2    White, H.D.3
  • 84
    • 78751664800 scopus 로고    scopus 로고
    • Leukotriene inflammatory mediators meet their match
    • article 66ps3
    • Funk CD. Leukotriene inflammatory mediators meet their match. Sci Transl Med 2011; 3:article 66ps3.
    • (2011) Sci Transl Med , vol.3
    • Funk, C.D.1
  • 85
    • 77953642757 scopus 로고    scopus 로고
    • Treatment with 5-lipoxygenase inhibitor via-2291 (atreleuton) in patients with recent acute coronary syndrome
    • Tardif JC, L'allier PL, Ibrahim R, et al. Treatment with 5-lipoxygenase inhibitor VIA-2291 (Atreleuton) in patients with recent acute coronary syndrome. Circ Cardiovasc Imaging 2010; 3:298-307.
    • (2010) Circ Cardiovasc Imaging , vol.3 , pp. 298-307
    • Tardif, J.C.1    Lallier, P.L.2    Ibrahim, R.3
  • 87
    • 80255129385 scopus 로고    scopus 로고
    • Perspectives and opportunities for nanomedicine in the management of atherosclerosis
    • This is an excellent review on recent advantages in nanomedicine in atherosclerosis
    • Lobatto ME, Fuster V, Fayad ZA, Mulder WJ. Perspectives and opportunities for nanomedicine in the management of atherosclerosis. Nat Rev Drug Discov 2011; 10:835-852. This is an excellent review on recent advantages in nanomedicine in atherosclerosis.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 835-852
    • Lobatto, M.E.1    Fuster, V.2    Fayad, Z.A.3    Mulder, W.J.4
  • 88
    • 67349131909 scopus 로고    scopus 로고
    • Amphotericin b-entrapping lipid nanoparticles and their in vitro and in vivo characteristics
    • Jung SH, Lim DH, Jung SH, et al. Amphotericin B-entrapping lipid nanoparticles and their in vitro and in vivo characteristics. Eur J Pharm Sci 2009; 37:313-320.
    • (2009) Eur J Pharm Sci , vol.37 , pp. 313-320
    • Jung, S.H.1    Lim, D.H.2    Jung, S.H.3
  • 89
    • 84861669644 scopus 로고    scopus 로고
    • Doxil(r): The first fda-approved nano-drug: Lessons learned
    • Barenholz YC. Doxil(R): the first FDA-approved nano-drug: lessons learned. J Control Release 2012; 160:117-134.
    • (2012) J Control Release , vol.160 , pp. 117-134
    • Barenholz, Y.C.1
  • 90
    • 0038002438 scopus 로고    scopus 로고
    • Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes
    • DOI 10.1002/art.11140
    • Metselaar JM, Wauben MH, Wagenaar-Hilbers JP, et al. Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes. Arthritis Rheum 2003; 48:2059-2066. (Pubitemid 36828702)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.7 , pp. 2059-2066
    • Metselaar, J.M.1    Wauben, M.H.M.2    Wagenaar-Hilbers, J.P.A.3    Boerman, O.C.4    Storm, G.5
  • 92
    • 84870024969 scopus 로고    scopus 로고
    • Silencing inflammatory activity by injecting nanocort in patients at risk for atherosclerotic disease (silence
    • Stroes ESG. Silencing inflammatory activity by injecting nanocort in patients at risk for atherosclerotic disease (SILENCE). ClinicalTrials gov Identifier: NCT01601106 2012.
    • (2012) ClinicalTrials gov Identifier: NCT01601106
    • Stroes, E.S.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.