-
1
-
-
84861185907
-
Molecular networks that regulate cancer metastasis
-
Spano D., Heck C., De Antonellis P., Christofori G., Zollo M. Molecular networks that regulate cancer metastasis. Semin. Cancer Biol. 2012, 22:234-249.
-
(2012)
Semin. Cancer Biol.
, vol.22
, pp. 234-249
-
-
Spano, D.1
Heck, C.2
De Antonellis, P.3
Christofori, G.4
Zollo, M.5
-
2
-
-
0036904661
-
Cell motility insights from the backstage
-
Bailly M., Condeelis J. Cell motility insights from the backstage. Nat. Cell Biol. 2002, 4:E292-E294.
-
(2002)
Nat. Cell Biol.
, vol.4
-
-
Bailly, M.1
Condeelis, J.2
-
3
-
-
34247468876
-
Regulation of the actin cytoskeleton in cancer cell migration and invasion
-
Yamaguchi H., Condeelis J. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim. Biophys. Acta 2007, 1773:642-652.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 642-652
-
-
Yamaguchi, H.1
Condeelis, J.2
-
4
-
-
42049092972
-
Regulation of actin assembly associated with protrusion and adhesion in cell migration
-
Le Clainche C., Carlier M.F. Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol. Rev. 2008, 88:489-513.
-
(2008)
Physiol. Rev.
, vol.88
, pp. 489-513
-
-
Le Clainche, C.1
Carlier, M.F.2
-
5
-
-
77956459044
-
Rac and Rho GTPases in cancer cell motility control
-
Parri M., Chiarugi P. Rac and Rho GTPases in cancer cell motility control. Cell Commun. Signal 2010, 8:23.
-
(2010)
Cell Commun. Signal
, vol.8
, pp. 23
-
-
Parri, M.1
Chiarugi, P.2
-
6
-
-
79955036682
-
RhoA can lead the way in tumor cell invasion and metastasis
-
Struckhoff A.P., Rana M.K., Worthylake R.A. RhoA can lead the way in tumor cell invasion and metastasis. Front. Biosci. 2011, 16:1915-1926.
-
(2011)
Front. Biosci.
, vol.16
, pp. 1915-1926
-
-
Struckhoff, A.P.1
Rana, M.K.2
Worthylake, R.A.3
-
7
-
-
79551561001
-
Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53
-
Timpson P., McGhee E.J., Morton J.P., von Kriegsheim A., Schwarz J.P., Karim S.A., Doyle B., Quinn J.A., Carragher N.O., Edward M., Olson M.F., Frame M.C., Brunton V.G., Sansom O.J., Anderson K.I. Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. Cancer Res. 2011, 71:747-757.
-
(2011)
Cancer Res.
, vol.71
, pp. 747-757
-
-
Timpson, P.1
McGhee, E.J.2
Morton, J.P.3
von Kriegsheim, A.4
Schwarz, J.P.5
Karim, S.A.6
Doyle, B.7
Quinn, J.A.8
Carragher, N.O.9
Edward, M.10
Olson, M.F.11
Frame, M.C.12
Brunton, V.G.13
Sansom, O.J.14
Anderson, K.I.15
-
8
-
-
69949104482
-
A genetically encoded photoactivatable Rac controls the motility of living cells
-
Wu Y.I., Frey D., Lungu O.I., Jaehrig A., Schlichting I., Kuhlman B., Hahn K.M. A genetically encoded photoactivatable Rac controls the motility of living cells. Nature 2009, 461:104-108.
-
(2009)
Nature
, vol.461
, pp. 104-108
-
-
Wu, Y.I.1
Frey, D.2
Lungu, O.I.3
Jaehrig, A.4
Schlichting, I.5
Kuhlman, B.6
Hahn, K.M.7
-
9
-
-
62449294770
-
The actin cytoskeleton in cancer cell motility
-
Olson M.F., Sahai E. The actin cytoskeleton in cancer cell motility. Clin. Exp. Metastasis 2009, 26:273-287.
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 273-287
-
-
Olson, M.F.1
Sahai, E.2
-
10
-
-
23944489900
-
Structure and dynamics of the homodimeric dynein light chain km23
-
Ilangovan U., Ding W., Zhong Y., Wilson C.L., Groppe J.C., Trbovich J.T., Zuniga J., Demeler B., Tang Q., Gao G., Mulder K.M., Hinck A.P. Structure and dynamics of the homodimeric dynein light chain km23. J. Mol. Biol. 2005, 352:338-354.
-
(2005)
J. Mol. Biol.
, vol.352
, pp. 338-354
-
-
Ilangovan, U.1
Ding, W.2
Zhong, Y.3
Wilson, C.L.4
Groppe, J.C.5
Trbovich, J.T.6
Zuniga, J.7
Demeler, B.8
Tang, Q.9
Gao, G.10
Mulder, K.M.11
Hinck, A.P.12
-
11
-
-
34249795753
-
Km23, a transforming growth factor-beta signaling component, is infrequently mutated in human colorectal and gastric cancers
-
Kang H.C., Kim I.J., Kim K., Yoon H.J., Jang S.G., Park J.G. km23, a transforming growth factor-beta signaling component, is infrequently mutated in human colorectal and gastric cancers. Cancer Genet Cytogenet 2007, 175:173-174.
-
(2007)
Cancer Genet Cytogenet
, vol.175
, pp. 173-174
-
-
Kang, H.C.1
Kim, I.J.2
Kim, K.3
Yoon, H.J.4
Jang, S.G.5
Park, J.G.6
-
12
-
-
33745697754
-
Genetic and epigenetic analysis of the putative tumor suppressor km23 in primary ovarian, breast, and colorectal cancers
-
Campbell I.G., Phillips W.A., Choong D.Y. Genetic and epigenetic analysis of the putative tumor suppressor km23 in primary ovarian, breast, and colorectal cancers. Clin. Cancer Res. 2006, 12:3713-3715.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 3713-3715
-
-
Campbell, I.G.1
Phillips, W.A.2
Choong, D.Y.3
-
13
-
-
1842584441
-
The roadblock light chains are ubiquitous components of cytoplasmic dynein that form homo and heterodimers
-
Nikulina K., Patel-King R.S., Takebe S., Pfister K.K., King S.M. The roadblock light chains are ubiquitous components of cytoplasmic dynein that form homo and heterodimers. Cell Motil. Cytoskeleton 2004, 57:233-245.
-
(2004)
Cell Motil. Cytoskeleton
, vol.57
, pp. 233-245
-
-
Nikulina, K.1
Patel-King, R.S.2
Takebe, S.3
Pfister, K.K.4
King, S.M.5
-
14
-
-
0035960907
-
Identification of two novel human dynein light chain genes DNLC2A and DNLC2B and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients
-
Jiang J., Yu L., Huang X., Chen X., Li D., Zhang Y., Tang L., Zhao S. Identification of two novel human dynein light chain genes DNLC2A and DNLC2B and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients. Gene 2001, 281:103-113.
-
(2001)
Gene
, vol.281
, pp. 103-113
-
-
Jiang, J.1
Yu, L.2
Huang, X.3
Chen, X.4
Li, D.5
Zhang, Y.6
Tang, L.7
Zhao, S.8
-
15
-
-
0036911117
-
A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein
-
Tang Q., Staub C.M., Gao G., Jin Q., Wang Z., Ding W., Aurigemma R.E., Mulder K.M. A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. Mol. Biol. Cell 2002, 13:4484-4496.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 4484-4496
-
-
Tang, Q.1
Staub, C.M.2
Gao, G.3
Jin, Q.4
Wang, Z.5
Ding, W.6
Aurigemma, R.E.7
Mulder, K.M.8
-
16
-
-
27744443394
-
Cytoplasmic dynein nomenclature
-
Pfister K.K., Fisher E.M., Gibbons I.R., Hays T.S., Holzbaur E.L., McIntosh J.R., Porter M.E., Schroer T.A., Vaughan K.T., Witman G.B., King S.M., Vallee R.B. Cytoplasmic dynein nomenclature. J. Cell Biol. 2005, 171:411-413.
-
(2005)
J. Cell Biol.
, vol.171
, pp. 411-413
-
-
Pfister, K.K.1
Fisher, E.M.2
Gibbons, I.R.3
Hays, T.S.4
Holzbaur, E.L.5
McIntosh, J.R.6
Porter, M.E.7
Schroer, T.A.8
Vaughan, K.T.9
Witman, G.B.10
King, S.M.11
Vallee, R.B.12
-
17
-
-
84864386292
-
The TGFbeta receptor-interacting protein km23-1/DYNLRB1 plays an adaptor role in TGFbeta1 autoinduction via its association with Ras
-
Jin Q., Ding W., Mulder K.M. The TGFbeta receptor-interacting protein km23-1/DYNLRB1 plays an adaptor role in TGFbeta1 autoinduction via its association with Ras. J. Biol. Chem. 2012, 287:26453-26463.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 26453-26463
-
-
Jin, Q.1
Ding, W.2
Mulder, K.M.3
-
18
-
-
0034597558
-
Dynein light chains of the Roadblock/LC7 group belong to an ancient protein superfamily implicated in NTPase regulation
-
Koonin E.V., Aravind L. Dynein light chains of the Roadblock/LC7 group belong to an ancient protein superfamily implicated in NTPase regulation. Curr. Biol. 2000, 10:R774-R776.
-
(2000)
Curr. Biol.
, vol.10
-
-
Koonin, E.V.1
Aravind, L.2
-
19
-
-
80054934194
-
Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity
-
Miertzschke M., Koerner C., Vetter I.R., Keilberg D., Hot E., Leonardy S., Sogaard-Andersen L., Wittinghofer A. Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity. EMBO J. 2011, 30:4185-4197.
-
(2011)
EMBO J.
, vol.30
, pp. 4185-4197
-
-
Miertzschke, M.1
Koerner, C.2
Vetter, I.R.3
Keilberg, D.4
Hot, E.5
Leonardy, S.6
Sogaard-Andersen, L.7
Wittinghofer, A.8
-
20
-
-
77954874614
-
Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP
-
Leonardy S., Miertzschke M., Bulyha I., Sperling E., Wittinghofer A., Sogaard-Andersen L. Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP. EMBO J. 2010, 29:2276-2289.
-
(2010)
EMBO J.
, vol.29
, pp. 2276-2289
-
-
Leonardy, S.1
Miertzschke, M.2
Bulyha, I.3
Sperling, E.4
Wittinghofer, A.5
Sogaard-Andersen, L.6
-
21
-
-
77955015657
-
A bacterial Ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility
-
Zhang Y., Franco M., Ducret A., Mignot T. A bacterial Ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility. PLoS Biol. 2010, 8:e1000430.
-
(2010)
PLoS Biol.
, vol.8
-
-
Zhang, Y.1
Franco, M.2
Ducret, A.3
Mignot, T.4
-
22
-
-
33746999958
-
C-Fos is required for TGFbeta1 production and the associated paracrine migratory effects of human colon carcinoma cells
-
Liu G., Ding W., Liu X., Mulder K.M. c-Fos is required for TGFbeta1 production and the associated paracrine migratory effects of human colon carcinoma cells. Mol. Carcinog. 2006, 45:582-593.
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 582-593
-
-
Liu, G.1
Ding, W.2
Liu, X.3
Mulder, K.M.4
-
23
-
-
84862979557
-
MS analysis reveals O-methylation of L-lactate dehydrogenase from pancreatic ductal adenocarcinoma cells
-
Zhou W., Capello M., Fredolini C., Racanicchi L., Piemonti L., Liotta L.A., Novelli F., Petricoin E.F. MS analysis reveals O-methylation of L-lactate dehydrogenase from pancreatic ductal adenocarcinoma cells. Electrophoresis 2012, 33:1850-1854.
-
(2012)
Electrophoresis
, vol.33
, pp. 1850-1854
-
-
Zhou, W.1
Capello, M.2
Fredolini, C.3
Racanicchi, L.4
Piemonti, L.5
Liotta, L.A.6
Novelli, F.7
Petricoin, E.F.8
-
24
-
-
34547105808
-
Requirement for the dynein light chain km23-1 in a Smad2-dependent transforming growth factor-beta signaling pathway
-
Jin Q., Ding W., Mulder K.M. Requirement for the dynein light chain km23-1 in a Smad2-dependent transforming growth factor-beta signaling pathway. J. Biol. Chem. 2007, 282:19122-19132.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 19122-19132
-
-
Jin, Q.1
Ding, W.2
Mulder, K.M.3
-
25
-
-
0033081753
-
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
-
Ren X.D., Kiosses W.B., Schwartz M.A. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 1999, 18:578-585.
-
(1999)
EMBO J.
, vol.18
, pp. 578-585
-
-
Ren, X.D.1
Kiosses, W.B.2
Schwartz, M.A.3
-
26
-
-
79959208404
-
Identification and functional analysis of epigenetically silenced microRNAs in colorectal cancer cells
-
Yan H., Choi A.J., Lee B.H., Ting A.H. Identification and functional analysis of epigenetically silenced microRNAs in colorectal cancer cells. PloS One 2011, 6:e20628.
-
(2011)
PloS One
, vol.6
-
-
Yan, H.1
Choi, A.J.2
Lee, B.H.3
Ting, A.H.4
-
27
-
-
0033434080
-
Probability-based protein identification by searching sequence databases using mass spectrometry data
-
Perkins D.N., Pappin D.J., Creasy D.M., Cottrell J.S. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999, 20:3551-3567.
-
(1999)
Electrophoresis
, vol.20
, pp. 3551-3567
-
-
Perkins, D.N.1
Pappin, D.J.2
Creasy, D.M.3
Cottrell, J.S.4
-
28
-
-
72949101770
-
Coronin 1C negatively regulates cell-matrix adhesion and motility of intestinal epithelial cells
-
Samarin S.N., Koch S., Ivanov A.I., Parkos C.A., Nusrat A. Coronin 1C negatively regulates cell-matrix adhesion and motility of intestinal epithelial cells. Biochem. Biophys. Res. Commun. 2010, 391:394-400.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 394-400
-
-
Samarin, S.N.1
Koch, S.2
Ivanov, A.I.3
Parkos, C.A.4
Nusrat, A.5
-
30
-
-
49949102465
-
TGFbeta-induced RhoA activation and fibronectin production in mesangial cells require caveolae
-
Peng F., Zhang B., Wu D., Ingram A.J., Gao B., Krepinsky J.C. TGFbeta-induced RhoA activation and fibronectin production in mesangial cells require caveolae. Am. J. Physiol. Renal Physiol. 2008, 295:F153-164.
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.295
-
-
Peng, F.1
Zhang, B.2
Wu, D.3
Ingram, A.J.4
Gao, B.5
Krepinsky, J.C.6
-
31
-
-
0036197606
-
Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA
-
Edlund S., Landstrom M., Heldin C.H., Aspenstrom P. Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA. Mol. Biol. Cell 2002, 13:902-914.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 902-914
-
-
Edlund, S.1
Landstrom, M.2
Heldin, C.H.3
Aspenstrom, P.4
-
32
-
-
0035185853
-
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
-
Bhowmick N.A., Ghiassi M., Bakin A., Aakre M., Lundquist C.A., Engel M.E., Arteaga C.L., Moses H.L. Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol. Biol. Cell 2001, 12:27-36.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 27-36
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Bakin, A.3
Aakre, M.4
Lundquist, C.A.5
Engel, M.E.6
Arteaga, C.L.7
Moses, H.L.8
-
34
-
-
33746375657
-
Coronins: the return of the crown
-
Uetrecht A.C., Bear J.E. Coronins: the return of the crown. Trends Cell Biol. 2006, 16:421-426.
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 421-426
-
-
Uetrecht, A.C.1
Bear, J.E.2
-
35
-
-
78049414514
-
Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis
-
Gandhi M., Jangi M., Goode B.L. Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis. J. Biol. Chem. 2010, 285:34899-34908.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34899-34908
-
-
Gandhi, M.1
Jangi, M.2
Goode, B.L.3
-
36
-
-
71749095987
-
The cofilin activity cycle in lamellipodia and invadopodia
-
Oser M., Condeelis J. The cofilin activity cycle in lamellipodia and invadopodia. J. Cell Biochem. 2009, 108:1252-1262.
-
(2009)
J. Cell Biochem.
, vol.108
, pp. 1252-1262
-
-
Oser, M.1
Condeelis, J.2
-
37
-
-
70350647605
-
Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge
-
Nalbant P., Chang Y.C., Birkenfeld J., Chang Z.F., Bokoch G.M. Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge. Mol. Biol. Cell 2009, 20:4070-4082.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4070-4082
-
-
Nalbant, P.1
Chang, Y.C.2
Birkenfeld, J.3
Chang, Z.F.4
Bokoch, G.M.5
-
38
-
-
45349084318
-
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
-
Sakurai-Yageta M., Recchi C., Le Dez G., Sibarita J.B., Daviet L., Camonis J., D'Souza-Schorey C., Chavrier P. The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J. Cell Biol. 2008, 181:985-998.
-
(2008)
J. Cell Biol.
, vol.181
, pp. 985-998
-
-
Sakurai-Yageta, M.1
Recchi, C.2
Le Dez, G.3
Sibarita, J.B.4
Daviet, L.5
Camonis, J.6
D'Souza-Schorey, C.7
Chavrier, P.8
-
39
-
-
64149107339
-
Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP
-
Mori K., Amano M., Takefuji M., Kato K., Morita Y., Nishioka T., Matsuura Y., Murohara T., Kaibuchi K. Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP. J. Biol. Chem. 2009, 284:5067-5076.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5067-5076
-
-
Mori, K.1
Amano, M.2
Takefuji, M.3
Kato, K.4
Morita, Y.5
Nishioka, T.6
Matsuura, Y.7
Murohara, T.8
Kaibuchi, K.9
-
40
-
-
33947319481
-
Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors
-
Hopkins A.M., Pineda A.A., Winfree L.M., Brown G.T., Laukoetter M.G., Nusrat A. Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors. Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 292:G806-817.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
-
-
Hopkins, A.M.1
Pineda, A.A.2
Winfree, L.M.3
Brown, G.T.4
Laukoetter, M.G.5
Nusrat, A.6
-
41
-
-
79953720901
-
Downregulation of SOK1 promotes the migration of MCF-7 cells
-
Chen X.D., Cho C.Y. Downregulation of SOK1 promotes the migration of MCF-7 cells. Biochem. Biophys. Res. Commun. 2011, 407:389-392.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.407
, pp. 389-392
-
-
Chen, X.D.1
Cho, C.Y.2
-
42
-
-
77949316749
-
Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities
-
Windhorst S., Fliegert R., Blechner C., Mollmann K., Hosseini Z., Gunther T., Eiben M., Chang L., Lin H.Y., Fanick W., Schumacher U., Brandt B., Mayr G.W. Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities. J. Biol. Chem. 2010, 285:5541-5554.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 5541-5554
-
-
Windhorst, S.1
Fliegert, R.2
Blechner, C.3
Mollmann, K.4
Hosseini, Z.5
Gunther, T.6
Eiben, M.7
Chang, L.8
Lin, H.Y.9
Fanick, W.10
Schumacher, U.11
Brandt, B.12
Mayr, G.W.13
-
43
-
-
79960913038
-
Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells
-
Windhorst S., Kalinina T., Schmid K., Blechner C., Kriebitzsch N., Hinsch R., Chang L., Herich L., Schumacher U., Mayr G.W. Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells. Int. J. Cancer 2011, 129:1300-1309.
-
(2011)
Int. J. Cancer
, vol.129
, pp. 1300-1309
-
-
Windhorst, S.1
Kalinina, T.2
Schmid, K.3
Blechner, C.4
Kriebitzsch, N.5
Hinsch, R.6
Chang, L.7
Herich, L.8
Schumacher, U.9
Mayr, G.W.10
|