c-Fos is required for TGFβ1 production and the associated paracrine migratory effects of human colon carcinoma cells

Molecular Carcinogenesis

Volumn 45, Issue 8, 2006, Pages 582-593

  Liu, Guangming ^a   Ding, Wei ^a   Liu, Xin ^a   Mulder, Kathleen M ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Activator protein 1; Colon carcinoma; Fos; Paracrine; Small interfering RNA; Transcription; Transforming growth factor

Indexed keywords

SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CARCINOMA CELL; CELL MIGRATION; COLON CARCINOMA; EPITHELIUM CELL; EXTRACELLULAR MATRIX; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MITOGENESIS; ONCOGENE C FOS; PARACRINE SIGNALING; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOMA; CELL MOVEMENT; COCULTURE TECHNIQUES; COLONIC NEOPLASMS; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; NIH 3T3 CELLS; PARACRINE COMMUNICATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-FOS; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR AP-1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33746999958     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20189     Document Type: Article

References (50)

1. Yue J, Mulder KM. Transforming growth factor-β signal transduction in epithelial cells. Pharmacol Ther 2001;91:1-34.
2. Akhurst RJ. TGF-β antagonists: Why suppress a tumor suppressor? J Clin Invest 2002;109:1533-1536.
3. Wakefield LM, Roberts AB. TGF-β signaling: Positive and negative effects on tumorigenesis. Curr Opin Genet Dev 2002;12:22-29.
4. Tuxhorn JA, McAlhany SJ, Yang F, Dang TD, Rowley DR. Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model. Cancer Res 2002;62:6021-6025.
5. Hsiao YW, Liao KW, Hung SW, Chu RM. Tumor-infiltrating lymphocyte secretion of IL-6 antagonizes tumor-derived TGF-β1 and restores the lymphokine-activated killing activity. J Immunol 2004;172:1508-1514.
6. Terabe M, Matsui S, Park JM, et al. Transforming growth factor-β production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence. J Exp Med 2003;198:1741-1752.
7. Wright N, de Lera TL, Garcia-Moruja C, et al. Transforming growth factor-beta1 down-regulates expression of chemokine stromal cell-derived factor-1: Functional consequences in cell migration and adhesion. Blood 2003;102:1978-1984.
8. Kao JY, Gong Y, Chen CM, Zheng QD, Chen JJ. Tumor-derived TGF-β reduces the efficacy of dendritic cell/tumor fusion vaccine. J Immunol 2003;170:3806-3811.
9. Hirashima Y, Kobayashi H, Suzuki M, Tanaka Y, Kanayama N, Terao T. Transforming growth factor-beta1 produced by ovarian cancer cell line HRA stimulates attachment and invasion through an up-regulation of plasminogen activator inhibitor type-1 in human peritoneal mesothelial cells. J Biol Chem 2003;278:26793-26802.
10. Kuga H, Morisaki T, Nakamura K, et al. Interferon-gamma suppresses transforming growth factor-β-induced invasion of gastric carcinoma cells through cross-talk of Smad pathway in a three-dimensional culture model. Oncogene 2003;22:7838-7847.
11. Derynck R, Akhurst RJ, Balmain A. TGF-β signaling in tumor suppression and cancer progression. Nat Genet 2001;29:117-129.
12. Kim SJ, Glick A, Sporn MB, Roberts AB. Characterization of the promoter region of the human transforming growth factor-β1 gene. J Biol Chem 1989;264:402-408.
13. Samatar AA, Wang L, Mirza A, Koseoglu S, Liu S, Kumar CC. Transforming growth factor-β2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor. J Biol Chem 2002;277:28118-28126.
14. Lafyatis R, Lechleider R, Kim SJ, Jakowlew S, Roberts AB, Sporn MB. Structural and functional characterization of the transforming growth factor β3 promoter. A cAMP-responsive element regulates basal and induced transcription. J Biol Chem 1990;265:19128-19136.
15. Yue J, Mulder KM. Requirement of Ras/MAPK pathway activation by transforming growth factor β for transforming growth factor beta 1 production in a smad-dependent pathway. J Biol Chem 2000;275:30765-30773.
16. Kim SJ, Angel P, Lafyatis R, et al. Autoinduction of transforming growth factor β1 is mediated by the AP-1 complex. Mol Cell Biol 1990;10:1492-1497.
17. Kim SJ, Jeang KT, Glick AB, Sporn MB, Roberts AB. Promoter sequences of the human transforming growth factor-β1 gene responsive to transforming growth factor-β1 autoinduction. J Biol Chem 1989;264:7041-7045.
18. Mulder KM, Segarini PR, Morris SL, Ziman JM, Choi HG. Role of receptor complexes in resistance or sensitivity to growth inhibition by TGFβ in intestinal epithelial cell clones. J Cell Physiol 1993;154:162-174.
19. Mulder KM, Morris SL. Activation of p21ras by transforming growth factor β in epithelial cells. J Biol Chem 1992;267:5029-5031.
20. Ye S-C, Foster JM, Li WH, et al. Contextual effects of transforming growth factor β on the tumorigenicity of human colon carcinoma cells. Cancer Res 1999;59:4725-4731.
21. Wu SP, Theodorescu D, Kerbel RS, et al. TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector. J Cell Biol 1992;116:187-196.
22. Mulder KM, Brattain MG. Growth factor expression and response in human colon carcinoma cells. In: Augenlicht L, editor. The cell and molecular biology of colon cancer. Boca Raton: LRC Press; 1989. p. 45-67.
23. Brattain MG, Levine AE, Chakrabarty S, Yeoman LC, Willson JK, Long B. Heterogeneity of human colon carcinoma. Cancer Metastasis Rev 1984;3:177-191.
24. Boyd DD, Levine AE, Brattain DE, McKnight MK, Brattain MG. Comparison of growth requirements of two human intratumoral colon carcinoma cell lines in monolayer and soft agarose. Cancer Res 1988;48:2469-2474.
25. Liu G, Chen N, Kaji A, Bode AM, Ryan CA, Dong Z. Proteinase inhibitors I and II from potatoes block UVB-induced AP-1 activity by regulating the AP-1 protein compositional patterns in JB6 cells. Proc Natl Acad Sci USA 2001;98:5786-5791.
26. Weinmann AS, Bartley SM, Zhang MQ, Zhang T, Farnham PJ. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol Cell Biol 2001;21:6820-6832.
27. Ventura JJ, Kennedy NJ, Flavell RA, Davis RJ. JNK regulates autocrine expression of TGF-β1. Mol Cell 2004;15:269-278.
28. Bi Y, Stuelten CH, Kilts T, et al. Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. J Biol Chem 2005;280:30481-30489.
29. Grimsley CM, Kinchen JM, Tosello-Trampont AC, et al. Dock180 and ELMO1 proteins cooperate to promote evolutionary conserved Rac-dependent cell migration. J Biol Chem 2004;279:6087-6097.
30. Koivunen E, Ranta TM, Annila A, et al. Inhibition of β2 integrin-mediated leukocyte cell adhesion by leucine-leucine-glycine motif-containing peptides. J Cell Biol 2001;153:905-916.
31. Hartsough ME, Mulder KM. Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells. J Biol Chem 1995;270:7117-7124.
32. Franco L, Zocchi E, Usai C, et al. Paracrine roles of NAD+ and cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts. J Biol Chem 2001;276:21642-21648.
33. Guida L, Bruzzone S, Sturla L, Franco L, Zocchi E, De Flora A. Equilibrative and concentrative nucleoside transporters mediate influx of extracellular cyclic ADP-ribose into 3T3 murine fibroblasts. J Biol Chem 2002;277:47097-47105.
34. Geiser AG, Kim SJ, Roberts AB, Sporn MB. Characterization of the mouse transforming growth factor-β1 promoter and activation by the Ha-ras oncogene. Mol Cell Biol 1991;11:84-92.
35. Kim SJ, Denhez F, Kim KY, Holt JT, Sporn MB, Roberts AB. Activation of the second promoter of the transforming growth factor-β1 gene by transforming growth factor-beta 1 and phorbol ester occurs through the same target sequences. J Biol Chem 1989;264:19373-19378.
36. Eferl R, Wagner EF. AP-1: A double-edged sword in tumorigenesis. Nat Rev Cancer 2003;3:859-868.
37. Gong J, Ammanamanchi S, Ko TC, Brattain MG. Transforming growth factor β1 increases the stability of p21/WAF1/ CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells. Cancer Res 2003;63:3340-3346.
38. Van Obberghen-Schilling E, Roche NS, Flandern KC, Sporn MB, Roberts AB. Transforming growth factor β1 positively regulates its own expression in normal and transformed cells. J Biol Chem 1988;263:7741-7746.
39. Pfarr CM, Mechta F, Spyrou G, Lallemand D, Carillo S, Yaniv M. Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. Cell 1994;76:747-760.
40. Lasky SR, Iwata K, Rosmarin AG, Caprio DG, Maizel AL. Differential regulation of JunD by dihydroxycholecalciferol in human chronic myelogenous leukemia cells. J Biol Chem 1995;270:19676-19679.
41. McGill GG, Horstmann M, Widlund HR, et al. Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability. Cell 2002;109:707-718.
42. Reichmann E, Schwarz H, Deiner EM, et al. Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion. Cell 1992;71:1103-1116.
43. Saez E, Rutberg SE, Mueller E, et al. c-fos is required for malignant progression of skin tumors. Cell 1995;82:721-732.
44. Volm M, Drings P, Wodrich W. Prognostic significance of the expression of c-fos, c-jun and c-erbB-1 oncogene products in human squamous cell lung carcinomas. J Cancer Res Clin Oncol 1993;119:507-510.
45. Aoyagi K, Shima I, Wang M, Hu Y, Garcia FU, Stearns ME. Specific transcription factors prognostic for prostate cancer progression. Clin Cancer Res 1998;4:2153-2160.
46. Jochum W, Passegue E, Wagner EF. AP-1 in mouse development and tumorigenesis. Oncogene 2001;20:2401-2412.
47. Sherwood DR, Butler JA, Kramer JM, Sternberg PW. FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans. Cell 2005;121:951-962.
48. Schaeffer HJ, Weber MJ. Mitogen-activated protein kinases: Specific messages from ubiquitous messengers. Mol Cell Biol 1999;19:2435-2444.
49. Galetic I, Maira SM, Andjelkovic M, Hemmings BA. Negative regulation of ERK and Elk by protein kinase B modulates c-Fos transcription. J Biol Chem 2003;278:4416-4423.
50. Buard A, Zipfel PA, Frey RS, Mulder KM. Maintenance of growth factor signaling through Ras in human colon carcinoma cells containing K-ras mutations. Int J Cancer 1996;67:539-546.