Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities

Journal of Biological Chemistry

Volumn 285, Issue 8, 2010, Pages 5541-5554

  Windhorst, Sabine ^a   Fliegert, Ralf ^a   Blechner, Christine ^a   Möllmann, Katharina ^a   Hosseini, Zara ^a   Günther, Thomas ^a   Eiben, Maike ^a   Chang, Lydia ^a   Lin, Hong Ying ^a   Fanick, Werner ^a   Schumacher, Udo ^a   Brandt, Burkhard ^a   Mayr, Georg W ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN CYTOSKELETON; ACTIN FILAMENT; CANCER CELLS; CELL MOTILITY; CELLULAR MIGRATION; DIFFERENT MECHANISMS; F-ACTIN; FUNCTIONAL ACTIVITIES; GROWTH FACTOR; HUMAN TUMOR CELLS; IN-VITRO; INOSITOL PHOSPHATE; MECHANISTIC STUDIES; METASTATIC POTENTIAL; METASTATIC TUMORS; MOUSE MODELS; PROMOTING PROTEIN; STIMULATED CELLS; STORE-OPERATED CALCIUM ENTRIES; TUMOR CELL MIGRATION; TUMOR CELLS; TUMOR PROGRESSIONS;

ALCOHOLS; BIOACTIVITY; CALCIUM; CELL CULTURE; PEPTIDES; SUGARS;

TUMORS;

F ACTIN; GROWTH FACTOR; INOSITOL 1,3,4,5 TETRAKISPHOSPHATE; INOSITOL TRISPHOSPHATE 3 KINASE; ACTIN; CALCIUM; INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE; INOSITOL PHOSPHATE; INOSITOL-1,3,4,5-TETRAKISPHOSPHATE; PHOSPHATASE; PHOSPHOTRANSFERASE; TUMOR PROTEIN;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; HUMAN; HUMAN CELL; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TUMOR CELL; TUMOR XENOGRAFT; ANIMAL; CANCER TRANSPLANTATION; CELL MOTION; CELL STRAIN HEPG2; CYTOSKELETON; DRUG ANTAGONISM; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; GENE EXPRESSION REGULATION; METABOLISM; MICROFILAMENT; MOUSE MUTANT; PATHOLOGY; XENOGRAFT;

ACTINS; ANIMALS; CALCIUM; CELL MOVEMENT; CYTOSKELETON; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; INOSITOL PHOSPHATES; MICE; MICE, SCID; MICROFILAMENTS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); TRANSPLANTATION, HETEROLOGOUS;

EID: 77949316749     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.047050     Document Type: Article

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