Accumulation of staphylococcal Panton-Valentine leukocidin in the detergent-resistant membrane microdomains on the target cells is essential for its cytotoxicity

FEMS Immunology and Medical Microbiology

Volumn 66, Issue 3, 2012, Pages 343-352

  Nishiyama, Akihito ^a   Isobe, Hirokazu ^a   Iwao, Yasuhisa ^a   Takano, Tomomi ^a   Hung, Wei Chun ^a   Taneike, Ikue ^a   Nakagawa, Saori ^a   Dohmae, Soshi ^a   Iwakura, Nobuhiro ^a   Yamamoto, Tatsuo ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Community acquired methicillin resistant Staphylococcus aureus; Cytotoxicity; Detergent resistant membrane microdomains; Human polymorphonuclear neutrophils; Panton Valentine leukocidin; Toxin accumulation

Indexed keywords

GANGLIOSIDE GM1; PANTON VALENTINE LEUKOCIDIN;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL STRAIN HL 60; COMPLEX FORMATION; CYTOTOXICITY; GRANULOCYTE; HUMAN; HUMAN CELL; MONOCYTE; NUCLEOTIDE SEQUENCE; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

BACTERIAL TOXINS; CELL DEATH; CELLS, CULTURED; EXOTOXINS; HUMANS; LEUKOCIDINS; MEMBRANE MICRODOMAINS; MONOCYTES; NEUTROPHILS; STAPHYLOCOCCUS;

EID: 84869868567     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2012.01027.x     Document Type: Article

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