Viral mutation rates: Modelling the roles of within-host viral dynamics and the trade-off between replication fidelity and speed

Proceedings of the Royal Society B: Biological Sciences

Volumn 280, Issue 1750, 2013, Pages

  Regoes, Roland R ^a   Hamblin, Steven ^b   Tanaka, Mark M ^b  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Adaptation; Biochemical constraint; Mathematical model; Red Queen; Viral mutation rate; Virulence

Indexed keywords

BIOCHEMICAL COMPOSITION; GENOME; IMMUNE RESPONSE; LIFE HISTORY; MUTATION; NUMERICAL MODEL; RED QUEEN HYPOTHESIS; TRADE-OFF; VIRULENCE; VIRUS;

EID: 84869854859     PISSN: 09628452     EISSN: 14712954     Source Type: Journal    
DOI: 10.1098/rspb.2012.2047     Document Type: Article

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