메뉴 건너뛰기




Volumn 7, Issue 11, 2012, Pages

PPARγ Agonists Promote Oligodendrocyte Differentiation of Neural Stem Cells by Modulating Stemness and Differentiation Genes

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; BETA TUBULIN; CIGLITAZONE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; RETINOIC ACID;

EID: 84869854776     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050500     Document Type: Article
Times cited : (61)

References (72)
  • 1
    • 34247532433 scopus 로고    scopus 로고
    • Timing is everything: making neurons versus glia in the developing cortex
    • Miller FD, Gauthier AS, (2007) Timing is everything: making neurons versus glia in the developing cortex. Neuron 54: 357-369.
    • (2007) Neuron , vol.54 , pp. 357-369
    • Miller, F.D.1    Gauthier, A.S.2
  • 3
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage FH, (2000) Mammalian neural stem cells. Science 287: 1433-1438.
    • (2000) Science , vol.287 , pp. 1433-1438
    • Gage, F.H.1
  • 5
    • 0032176195 scopus 로고    scopus 로고
    • Stem cells of the central nervous system
    • Gage FH, (1998) Stem cells of the central nervous system. Curr Opin Neurobiol 8: 671-676.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 671-676
    • Gage, F.H.1
  • 6
    • 0030436269 scopus 로고    scopus 로고
    • Neuronal progenitor cells derived from the anterior subventricular zone of the neonatal rat forebrain continue to proliferate in vitro and express a neuronal phenotype
    • Luskin MB, Zigova T, Soteres BJ, Stewart RR, (1997) Neuronal progenitor cells derived from the anterior subventricular zone of the neonatal rat forebrain continue to proliferate in vitro and express a neuronal phenotype. Mol Cell Neurosci 8: 351-366.
    • (1997) Mol Cell Neurosci , vol.8 , pp. 351-366
    • Luskin, M.B.1    Zigova, T.2    Soteres, B.J.3    Stewart, R.R.4
  • 7
    • 0033404850 scopus 로고    scopus 로고
    • Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination
    • Nait-Oumesmar B, Decker L, Lachapelle F, Avellana-Adalid V, Bachelin C, et al. (1999) Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination. Eur J Neurosci 11: 4357-4366.
    • (1999) Eur J Neurosci , vol.11 , pp. 4357-4366
    • Nait-Oumesmar, B.1    Decker, L.2    Lachapelle, F.3    Avellana-Adalid, V.4    Bachelin, C.5
  • 8
    • 79959681732 scopus 로고    scopus 로고
    • In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics
    • Bonaguidi MA, Wheeler MA, Shapiro JS, Stadel RP, Sun GJ, et al. (2011) In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics. Cell 145: 1142-1155.
    • (2011) Cell , vol.145 , pp. 1142-1155
    • Bonaguidi, M.A.1    Wheeler, M.A.2    Shapiro, J.S.3    Stadel, R.P.4    Sun, G.J.5
  • 9
    • 0033254945 scopus 로고    scopus 로고
    • Cerebral angiogenesis shows nestin expression in endothelial cells
    • Mokry J, Nemecek S, (1999) Cerebral angiogenesis shows nestin expression in endothelial cells. Gen Physiol Biophys 18Suppl 1: 25-29.
    • (1999) Gen Physiol Biophys , vol.18 , pp. 25-29
    • Mokry, J.1    Nemecek, S.2
  • 11
    • 84979726329 scopus 로고    scopus 로고
    • Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
    • Pluchino S, Quattrini A, Brambilla E, Gritti A, Salani G, et al. (2003) Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 422: 688-694.
    • (2003) Nature , vol.422 , pp. 688-694
    • Pluchino, S.1    Quattrini, A.2    Brambilla, E.3    Gritti, A.4    Salani, G.5
  • 12
    • 0027368705 scopus 로고
    • The characterization of astrocyte cell lines that display properties of glial scar tissue
    • Groves AK, Entwistle A, Jat PS, Noble M, (1993) The characterization of astrocyte cell lines that display properties of glial scar tissue. Dev Biol 159: 87-104.
    • (1993) Dev Biol , vol.159 , pp. 87-104
    • Groves, A.K.1    Entwistle, A.2    Jat, P.S.3    Noble, M.4
  • 13
    • 0033007449 scopus 로고    scopus 로고
    • Expression of stem cell factor and c-kit receptor in neural cells after brain injury
    • Zhang SC, Fedoroff S, (1999) Expression of stem cell factor and c-kit receptor in neural cells after brain injury. Acta Neuropathol 97: 393-398.
    • (1999) Acta Neuropathol , vol.97 , pp. 393-398
    • Zhang, S.C.1    Fedoroff, S.2
  • 14
    • 0033232043 scopus 로고    scopus 로고
    • The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease
    • Shihabuddin LS, Palmer TD, Gage FH, (1999) The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease. Mol Med Today 5: 474-480.
    • (1999) Mol Med Today , vol.5 , pp. 474-480
    • Shihabuddin, L.S.1    Palmer, T.D.2    Gage, F.H.3
  • 15
    • 0032721901 scopus 로고    scopus 로고
    • From neural stem cells to myelinating oligodendrocytes
    • Rogister B, Ben-Hur T, Dubois-Dalcq M, (1999) From neural stem cells to myelinating oligodendrocytes. Mol Cell Neurosci 14: 287-300.
    • (1999) Mol Cell Neurosci , vol.14 , pp. 287-300
    • Rogister, B.1    Ben-Hur, T.2    Dubois-Dalcq, M.3
  • 16
    • 0035094340 scopus 로고    scopus 로고
    • The pleiotropic functions of peroxisome proliferator-activated receptor gamma
    • Debril MB, Renaud JP, Fajas L, Auwerx J, (2001) The pleiotropic functions of peroxisome proliferator-activated receptor gamma. J Mol Med 79: 30-47.
    • (2001) J Mol Med , vol.79 , pp. 30-47
    • Debril, M.B.1    Renaud, J.P.2    Fajas, L.3    Auwerx, J.4
  • 17
    • 0028321529 scopus 로고
    • Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
    • Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, et al. (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A 91: 7355-7359.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7355-7359
    • Kliewer, S.A.1    Forman, B.M.2    Blumberg, B.3    Ong, E.S.4    Borgmeyer, U.5
  • 18
    • 33644652740 scopus 로고    scopus 로고
    • Involvement of PPAR nuclear receptors in tissue injury and wound repair
    • Michalik L, Wahli W, (2006) Involvement of PPAR nuclear receptors in tissue injury and wound repair. J Clin Invest 116: 598-606.
    • (2006) J Clin Invest , vol.116 , pp. 598-606
    • Michalik, L.1    Wahli, W.2
  • 19
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer SA, Umesono K, Noonan DJ, Heyman RA, Evans RM, (1992) Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358: 771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 20
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, et al. (1995) 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83: 803-812.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5
  • 21
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B, (1998) PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391: 82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 22
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
    • Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, et al. (1995) A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83: 813-819.
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Willson, T.M.3    Patel, I.4    Morris, D.C.5
  • 23
    • 47749133827 scopus 로고    scopus 로고
    • Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cells
    • Paruchuri S, Jiang Y, Feng C, Francis SA, Plutzky J, et al. (2008) Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cells. J Biol Chem 283: 16477-16487.
    • (2008) J Biol Chem , vol.283 , pp. 16477-16487
    • Paruchuri, S.1    Jiang, Y.2    Feng, C.3    Francis, S.A.4    Plutzky, J.5
  • 24
    • 33748349646 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists: their role as vasoprotective agents in diabetes
    • Blaschke F, Caglayan E, Hsueh WA, (2006) Peroxisome proliferator-activated receptor gamma agonists: their role as vasoprotective agents in diabetes. Endocrinol Metab Clin North Am35: 561-574, ix.
    • (2006) Endocrinol Metab Clin North Am , vol.35
    • Blaschke, F.1    Caglayan, E.2    Hsueh, W.A.3
  • 25
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: nuclear control of metabolism
    • Desvergne B, Wahli W, (1999) Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20: 649-688.
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 26
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, et al. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270: 12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5
  • 27
    • 0035851187 scopus 로고    scopus 로고
    • PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen ED, Spiegelman BM, (2001) PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 276: 37731-37734.
    • (2001) J Biol Chem , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 28
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK, (1998) The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391: 79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 29
    • 34848892510 scopus 로고    scopus 로고
    • Combination therapy of rosiglitazone, a peroxisome proliferator-activated receptor-gamma ligand, and NMDA receptor antagonist (MK-801) on experimental embolic stroke in rats
    • Allahtavakoli M, Shabanzadeh A, Roohbakhsh A, Pourshanazari A, (2007) Combination therapy of rosiglitazone, a peroxisome proliferator-activated receptor-gamma ligand, and NMDA receptor antagonist (MK-801) on experimental embolic stroke in rats. Basic Clin Pharmacol Toxicol 101: 309-314.
    • (2007) Basic Clin Pharmacol Toxicol , vol.101 , pp. 309-314
    • Allahtavakoli, M.1    Shabanzadeh, A.2    Roohbakhsh, A.3    Pourshanazari, A.4
  • 31
    • 0036546185 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation
    • Natarajan C, Bright JJ, (2002) Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. Genes Immun 3: 59-70.
    • (2002) Genes Immun , vol.3 , pp. 59-70
    • Natarajan, C.1    Bright, J.J.2
  • 32
    • 20444398490 scopus 로고    scopus 로고
    • Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation
    • Luna-Medina R, Cortes-Canteli M, Alonso M, Santos A, Martinez A, et al. (2005) Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation. J Biol Chem 280: 21453-21462.
    • (2005) J Biol Chem , vol.280 , pp. 21453-21462
    • Luna-Medina, R.1    Cortes-Canteli, M.2    Alonso, M.3    Santos, A.4    Martinez, A.5
  • 33
    • 34250615440 scopus 로고    scopus 로고
    • NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders
    • Luna-Medina R, Cortes-Canteli M, Sanchez-Galiano S, Morales-Garcia JA, Martinez A, et al. (2007) NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders. J Neurosci 27: 5766-5776.
    • (2007) J Neurosci , vol.27 , pp. 5766-5776
    • Luna-Medina, R.1    Cortes-Canteli, M.2    Sanchez-Galiano, S.3    Morales-Garcia, J.A.4    Martinez, A.5
  • 34
    • 0033944415 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions
    • Bernardo A, Levi G, Minghetti L, (2000) Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions. Eur J Neurosci 12: 2215-2223.
    • (2000) Eur J Neurosci , vol.12 , pp. 2215-2223
    • Bernardo, A.1    Levi, G.2    Minghetti, L.3
  • 35
    • 0035693506 scopus 로고    scopus 로고
    • Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease
    • Landreth GE, Heneka MT, (2001) Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease. Neurobiol Aging 22: 937-944.
    • (2001) Neurobiol Aging , vol.22 , pp. 937-944
    • Landreth, G.E.1    Heneka, M.T.2
  • 36
    • 26444475416 scopus 로고    scopus 로고
    • Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs
    • Townsend KP, Pratico D, (2005) Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs. Faseb J 19: 1592-1601.
    • (2005) Faseb J , vol.19 , pp. 1592-1601
    • Townsend, K.P.1    Pratico, D.2
  • 37
    • 0037311051 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation
    • Kielian T, Drew PD, (2003) Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation. J Neurosci Res 71: 315-325.
    • (2003) J Neurosci Res , vol.71 , pp. 315-325
    • Kielian, T.1    Drew, P.D.2
  • 38
    • 0032737858 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor (PPARgamma) as a regulator of monocyte/macrophage function
    • Ricote M, Huang JT, Welch JS, Glass CK, (1999) The peroxisome proliferator-activated receptor (PPARgamma) as a regulator of monocyte/macrophage function. J Leukoc Biol 66: 733-739.
    • (1999) J Leukoc Biol , vol.66 , pp. 733-739
    • Ricote, M.1    Huang, J.T.2    Welch, J.S.3    Glass, C.K.4
  • 39
    • 33748119493 scopus 로고    scopus 로고
    • PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2
    • Raikwar HP, Muthian G, Rajasingh J, Johnson CN, Bright JJ, (2006) PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2. J Neuroimmunol 178: 76-86.
    • (2006) J Neuroimmunol , vol.178 , pp. 76-86
    • Raikwar, H.P.1    Muthian, G.2    Rajasingh, J.3    Johnson, C.N.4    Bright, J.J.5
  • 40
    • 33744962510 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation
    • Wada K, Nakajima A, Katayama K, Kudo C, Shibuya A, et al. (2006) Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation. J Biol Chem 281: 12673-12681.
    • (2006) J Biol Chem , vol.281 , pp. 12673-12681
    • Wada, K.1    Nakajima, A.2    Katayama, K.3    Kudo, C.4    Shibuya, A.5
  • 41
    • 78650253906 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands regulate neural stem cell proliferation and differentiation in vitro and in vivo
    • Morales-Garcia JA, Luna-Medina R, Alfaro-Cervello C, Cortes-Canteli M, Santos A, et al. (2011) Peroxisome proliferator-activated receptor gamma ligands regulate neural stem cell proliferation and differentiation in vitro and in vivo. Glia 59: 293-307.
    • (2011) Glia , vol.59 , pp. 293-307
    • Morales-Garcia, J.A.1    Luna-Medina, R.2    Alfaro-Cervello, C.3    Cortes-Canteli, M.4    Santos, A.5
  • 42
    • 77950272320 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state
    • Katura T, Moriya T, Nakahata N, (2010) 15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state. Mol Pharmacol 77: 601-611.
    • (2010) Mol Pharmacol , vol.77 , pp. 601-611
    • Katura, T.1    Moriya, T.2    Nakahata, N.3
  • 43
    • 78650066315 scopus 로고    scopus 로고
    • Biomimetic microenvironment modulates neural stem cell survival, migration, and differentiation
    • Stabenfeldt SE, Munglani G, Garcia AJ, LaPlaca MC, (2010) Biomimetic microenvironment modulates neural stem cell survival, migration, and differentiation. Tissue Eng Part A 16: 3747-3758.
    • (2010) Tissue Eng Part A , vol.16 , pp. 3747-3758
    • Stabenfeldt, S.E.1    Munglani, G.2    Garcia, A.J.3    LaPlaca, M.C.4
  • 44
    • 65549159120 scopus 로고    scopus 로고
    • Laminin promotes oligogliogenesis and increases MMPs activity in human neural stem cells of HUCB-NSC line
    • Sypecka J, Dragun-Szymczak P, Zalewska T, Domanska-Janik K, (2009) Laminin promotes oligogliogenesis and increases MMPs activity in human neural stem cells of HUCB-NSC line. Acta Neurobiol Exp (Wars) 69: 37-45.
    • (2009) Acta Neurobiol Exp (Wars) , vol.69 , pp. 37-45
    • Sypecka, J.1    Dragun-Szymczak, P.2    Zalewska, T.3    Domanska-Janik, K.4
  • 45
    • 56249129313 scopus 로고    scopus 로고
    • Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2
    • Sher F, Rossler R, Brouwer N, Balasubramaniyan V, Boddeke E, et al. (2008) Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2. Stem Cells 26: 2875-2883.
    • (2008) Stem Cells , vol.26 , pp. 2875-2883
    • Sher, F.1    Rossler, R.2    Brouwer, N.3    Balasubramaniyan, V.4    Boddeke, E.5
  • 46
    • 0037227099 scopus 로고    scopus 로고
    • Multipotent cell lineages in early mouse development depend on SOX2 function
    • Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, et al. (2003) Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 17: 126-140.
    • (2003) Genes Dev , vol.17 , pp. 126-140
    • Avilion, A.A.1    Nicolis, S.K.2    Pevny, L.H.3    Perez, L.4    Vivian, N.5
  • 47
    • 4744350000 scopus 로고    scopus 로고
    • Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells
    • Catena R, Tiveron C, Ronchi A, Porta S, Ferri A, et al. (2004) Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells. J Biol Chem 279: 41846-41857.
    • (2004) J Biol Chem , vol.279 , pp. 41846-41857
    • Catena, R.1    Tiveron, C.2    Ronchi, A.3    Porta, S.4    Ferri, A.5
  • 48
    • 0141594644 scopus 로고    scopus 로고
    • Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells
    • D'Amour KA, Gage FH, (2003) Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells. Proc Natl Acad Sci U S A 100Suppl 1: 11866-11872.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11866-11872
    • D'Amour, K.A.1    Gage, F.H.2
  • 49
    • 21744446893 scopus 로고    scopus 로고
    • SOX2 functions in adult neural stem cells
    • Episkopou V, (2005) SOX2 functions in adult neural stem cells. Trends Neurosci 28: 219-221.
    • (2005) Trends Neurosci , vol.28 , pp. 219-221
    • Episkopou, V.1
  • 50
    • 0035955511 scopus 로고    scopus 로고
    • Surface markers expressed by multipotent human and mouse neural progenitor cells include tetraspanins and non-protein epitopes
    • Klassen H, Schwartz MR, Bailey AH, Young MJ, (2001) Surface markers expressed by multipotent human and mouse neural progenitor cells include tetraspanins and non-protein epitopes. Neurosci Lett 312: 180-182.
    • (2001) Neurosci Lett , vol.312 , pp. 180-182
    • Klassen, H.1    Schwartz, M.R.2    Bailey, A.H.3    Young, M.J.4
  • 51
    • 70349330941 scopus 로고    scopus 로고
    • Anterior-posterior patterning of neural differentiated embryonic stem cells by canonical Wnts, Fgfs, Bmp4 and their respective antagonists
    • Hendrickx M, Van XH, Leyns L, (2009) Anterior-posterior patterning of neural differentiated embryonic stem cells by canonical Wnts, Fgfs, Bmp4 and their respective antagonists. Dev Growth Differ 51: 687-698.
    • (2009) Dev Growth Differ , vol.51 , pp. 687-698
    • Hendrickx, M.1    Van, X.H.2    Leyns, L.3
  • 53
    • 0034633771 scopus 로고    scopus 로고
    • Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity
    • Holmes FE, Mahoney S, King VR, Bacon A, Kerr NC, et al. (2000) Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proc Natl Acad Sci U S A 97: 11563-11568.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 11563-11568
    • Holmes, F.E.1    Mahoney, S.2    King, V.R.3    Bacon, A.4    Kerr, N.C.5
  • 54
    • 0034633760 scopus 로고    scopus 로고
    • Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons
    • O'Meara G, Coumis U, Ma SY, Kehr J, Mahoney S, et al. (2000) Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons. Proc Natl Acad Sci U S A 97: 11569-11574.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 11569-11574
    • O'Meara, G.1    Coumis, U.2    Ma, S.Y.3    Kehr, J.4    Mahoney, S.5
  • 55
    • 0023484637 scopus 로고
    • Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy
    • Hokfelt T, Wiesenfeld-Hallin Z, Villar M, Melander T, (1987) Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy. Neurosci Lett 83: 217-220.
    • (1987) Neurosci Lett , vol.83 , pp. 217-220
    • Hokfelt, T.1    Wiesenfeld-Hallin, Z.2    Villar, M.3    Melander, T.4
  • 56
    • 0031785205 scopus 로고    scopus 로고
    • Inducible galanin and GalR2 receptor system in motor neuron injury and regeneration
    • Burazin TC, Gundlach AL, (1998) Inducible galanin and GalR2 receptor system in motor neuron injury and regeneration. J Neurochem 71: 879-882.
    • (1998) J Neurochem , vol.71 , pp. 879-882
    • Burazin, T.C.1    Gundlach, A.L.2
  • 58
    • 79952220153 scopus 로고    scopus 로고
    • Phosphorylation state of Olig2 regulates proliferation of neural progenitors
    • Sun Y, Meijer DH, Alberta JA, Mehta S, Kane MF, et al. (2011) Phosphorylation state of Olig2 regulates proliferation of neural progenitors. Neuron 69: 906-917.
    • (2011) Neuron , vol.69 , pp. 906-917
    • Sun, Y.1    Meijer, D.H.2    Alberta, J.A.3    Mehta, S.4    Kane, M.F.5
  • 59
    • 27744570893 scopus 로고    scopus 로고
    • Agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma): a new compound with potent gastroprotective and ulcer healing properties
    • Brzozowski T, Konturek PC, Pajdo R, Kwiecien SN, Konturek S, et al. (2005) Agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma): a new compound with potent gastroprotective and ulcer healing properties. Inflammopharmacology 13: 317-330.
    • (2005) Inflammopharmacology , vol.13 , pp. 317-330
    • Brzozowski, T.1    Konturek, P.C.2    Pajdo, R.3    Kwiecien, S.N.4    Konturek, S.5
  • 60
    • 0036731222 scopus 로고    scopus 로고
    • Neural stem cells: progression of basic research and perspective for clinical application
    • Okano H, (2002) Neural stem cells: progression of basic research and perspective for clinical application. Keio J Med 51: 115-128.
    • (2002) Keio J Med , vol.51 , pp. 115-128
    • Okano, H.1
  • 61
    • 0037106090 scopus 로고    scopus 로고
    • Stem cell biology of the central nervous system
    • Okano H, (2002) Stem cell biology of the central nervous system. J Neurosci Res 69: 698-707.
    • (2002) J Neurosci Res , vol.69 , pp. 698-707
    • Okano, H.1
  • 62
    • 33745740520 scopus 로고    scopus 로고
    • Cross talk between the cardiovascular and nervous systems: neurotrophic effects of vascular endothelial growth factor (VEGF) and angiogenic effects of nerve growth factor (NGF)-implications in drug development
    • Lazarovici P, Marcinkiewicz C, Lelkes PI, (2006) Cross talk between the cardiovascular and nervous systems: neurotrophic effects of vascular endothelial growth factor (VEGF) and angiogenic effects of nerve growth factor (NGF)-implications in drug development. Curr Pharm Des 12: 2609-2622.
    • (2006) Curr Pharm Des , vol.12 , pp. 2609-2622
    • Lazarovici, P.1    Marcinkiewicz, C.2    Lelkes, P.I.3
  • 63
    • 4644344077 scopus 로고    scopus 로고
    • The role of BETA2/NeuroD1 in the development of the nervous system
    • Cho JH, Tsai MJ, (2004) The role of BETA2/NeuroD1 in the development of the nervous system. Mol Neurobiol 30: 35-47.
    • (2004) Mol Neurobiol , vol.30 , pp. 35-47
    • Cho, J.H.1    Tsai, M.J.2
  • 64
    • 0030297962 scopus 로고    scopus 로고
    • Molecular cloning of a human neuroD from a neuroblastoma cell line specifically expressed in the fetal brain and adult cerebellum
    • Yokoyama M, Nishi Y, Miyamoto Y, Nakamura M, Akiyama K, et al. (1996) Molecular cloning of a human neuroD from a neuroblastoma cell line specifically expressed in the fetal brain and adult cerebellum. Brain Res Mol Brain Res 42: 135-139.
    • (1996) Brain Res Mol Brain Res , vol.42 , pp. 135-139
    • Yokoyama, M.1    Nishi, Y.2    Miyamoto, Y.3    Nakamura, M.4    Akiyama, K.5
  • 65
    • 43449091944 scopus 로고    scopus 로고
    • PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function
    • Kaneto H, Miyatsuka T, Kawamori D, Yamamoto K, Kato K, et al. (2008) PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function. Endocr J 55: 235-252.
    • (2008) Endocr J , vol.55 , pp. 235-252
    • Kaneto, H.1    Miyatsuka, T.2    Kawamori, D.3    Yamamoto, K.4    Kato, K.5
  • 67
    • 0037008767 scopus 로고    scopus 로고
    • Variant forms of alpha-fetoprotein transcripts expressed in human hematopoietic progenitors. Implications for their developmental potential towards endoderm
    • Kubota H, Storms RW, Reid LM, (2002) Variant forms of alpha-fetoprotein transcripts expressed in human hematopoietic progenitors. Implications for their developmental potential towards endoderm. J Biol Chem 277: 27629-27635.
    • (2002) J Biol Chem , vol.277 , pp. 27629-27635
    • Kubota, H.1    Storms, R.W.2    Reid, L.M.3
  • 68
    • 6044267548 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells
    • Cheng J, Nakamura H, Imanishi H, Liu W, Morisaki T, et al. (2004) Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells. Biochem Biophys Res Commun 322: 458-464.
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 458-464
    • Cheng, J.1    Nakamura, H.2    Imanishi, H.3    Liu, W.4    Morisaki, T.5
  • 69
    • 33750037335 scopus 로고    scopus 로고
    • Thyroid hormone deficiency changes the distribution of oligodendrocyte/myelin markers during oligodendroglial differentiation in vitro
    • Younes-Rapozo V, Berendonk J, Savignon T, Manhaes AC, Barradas PC, (2006) Thyroid hormone deficiency changes the distribution of oligodendrocyte/myelin markers during oligodendroglial differentiation in vitro. Int J Dev Neurosci 24: 445-453.
    • (2006) Int J Dev Neurosci , vol.24 , pp. 445-453
    • Younes-Rapozo, V.1    Berendonk, J.2    Savignon, T.3    Manhaes, A.C.4    Barradas, P.C.5
  • 70
    • 5644239628 scopus 로고    scopus 로고
    • Phosphodiesterase-I alpha/autotaxin controls cytoskeletal organization and FAK phosphorylation during myelination
    • Fox MA, Alexander JK, Afshari FS, Colello RJ, Fuss B, (2004) Phosphodiesterase-I alpha/autotaxin controls cytoskeletal organization and FAK phosphorylation during myelination. Mol Cell Neurosci 27: 140-150.
    • (2004) Mol Cell Neurosci , vol.27 , pp. 140-150
    • Fox, M.A.1    Alexander, J.K.2    Afshari, F.S.3    Colello, R.J.4    Fuss, B.5
  • 71
    • 71349086971 scopus 로고    scopus 로고
    • PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway
    • Mo C, Chearwae W, Bright JJ, (2010) PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. Cell Signal 22: 495-500.
    • (2010) Cell Signal , vol.22 , pp. 495-500
    • Mo, C.1    Chearwae, W.2    Bright, J.J.3
  • 72
    • 33745821610 scopus 로고    scopus 로고
    • 15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells
    • Rajasingh J, Bright JJ, (2006) 15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells. Exp Cell Res 312: 2538-2546.
    • (2006) Exp Cell Res , vol.312 , pp. 2538-2546
    • Rajasingh, J.1    Bright, J.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.