MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 47, 2012, Pages 19374-19379

  Franzenburg, Sören ^a   Fraune, Sebastian ^a   Künzel, Sven ^b   Baines, John F ^a,b   Domazet Lošo, Tomislav ^a   Bosch, Thomas C G ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b MAX PLANCK INSTITUTE FOR EVOLUTIONARY BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN C JUN; TOLL LIKE RECEPTOR;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; EMBRYO DEVELOPMENT; GENE EXPRESSION PROFILING; HOST RESISTANCE; HYDRA; IN VIVO STUDY; INNATE IMMUNITY; MICROBIAL DIVERSITY; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; COLONY COUNT, MICROBIAL; DISEASE SUSCEPTIBILITY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HYDRA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MYELOID DIFFERENTIATION FACTOR 88; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS); CAENORHABDITIS ELEGANS; CNIDARIA; DROSOPHILA MELANOGASTER; HYDRA; HYDRA MAGNIPAPILLATA; INVERTEBRATA; METAZOA; NEMATOSTELLA VECTENSIS; VERTEBRATA;

EID: 84869848890     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213110109     Document Type: Article

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