Further evidence for the anti-inflammatory activity of oleocanthal: Inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes

Life Sciences

Volumn 91, Issue 23-24, 2012, Pages 1229-1235

  Scotece, Morena ^a   Gómez, Rodolfo ^a   Conde, Javier ^a   Lopez, Verónica ^a   Gómez Reino, Juan J ^a   Lago, Francisca ^b   Smith III, Amos B ^c   Gualillo, Oreste ^a  

^a Instituto de Investigación Sanitaria de Santiago de Compostela IDIS   (Spain)

^b Pediatric Nutrition Research Group Health Research Institute of Santiago de Compostela   (Spain)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Chemokines; Chondrocytes; Inflammation; Macrophages; Natural drugs; Nutraceuticals; Osteoarthritis

Indexed keywords

ANTIINFLAMMATORY AGENT; CARBENOXOLONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; NITRITE; OLEOCANTHAL; POLYPHENOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE CELL; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RESPONSE; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALDEHYDES; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CHEMOKINE CCL3; CHONDROCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; INTERLEUKIN-6; MACROPHAGES; MICE; MOLECULAR STRUCTURE; ORGANIC CHEMICALS; PHENOLS; REAL-TIME POLYMERASE CHAIN REACTION; TETRAZOLIUM SALTS; THIAZOLES;

MURINAE;

EID: 84869504888     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.09.012     Document Type: Article

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