Effects of orexin A on proliferation, survival, apoptosis and differentiation of 3T3-L1 preadipocytes into mature adipocytes

FEBS Letters

Volumn 586, Issue 23, 2012, Pages 4157-4164

  Skrzypski, M ^a,b   Kaczmarek, P ^b   Le, T T ^a   Wojciechowicz, T ^b   Pruszynska Oszmalek E ^b   Szczepankiewicz, D ^b   Sassek, M ^a,b   Arafat, A ^a,c   Wiedenmann, B ^a   Nowak, K W ^b   Strowski, M Z ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b POZNA UNIVERSITY OF LIFE SCIENCES   (Poland)

^c GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

Adipocyte; Apoptosis; Fibroblast; In vitro; Orexin A; Proliferation

Indexed keywords

CASPASE 3; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OREXIN A; PROTEIN KINASE B;

ADIPOCYTE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL PROTECTION; CELL STRAIN 3T3; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; APOPTOSIS; CASPASE 3; CELL DIFFERENTIATION; CELL PROLIFERATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROPEPTIDES; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84869502425     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.10.013     Document Type: Article

References (39)

1. F.M. Gregoire, C.M. Smas, and H.S. Sul Understanding adipocyte differentiation Physiol. Rev. 78 1998 783 809
2. R.K. Petersen, L. Madsen, L.M. Pedersen, P. Hallenborg, H. Hagland, K. Viste, S.O. Doskeland, and K. Kristiansen Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes Mol. Cell. Biol. 28 2008 3804 3816
3. C.M. Smas, L. Chen, L. Zhao, M.J. Latasa, and H.S. Sul Transcriptional repression of pref-1 by glucocorticoids promotes 3T3-L1 adipocyte differentiation J. Biol. Chem. 274 1999 12632 12641
4. A. Gagnon, C.S. Chen, and A. Sorisky Activation of protein kinase B and induction of adipogenesis by insulin in 3T3-L1 preadipocytes: contribution of phosphoinositide-3,4,5-trisphosphate versus phosphoinositide-3,4-bisphosphate Diabetes 48 1999 691 698
5. M. Skrzypski Orexin A stimulates glucose uptake, lipid accumulation and adiponectin secretion from 3T3-L1 adipocytes and isolated primary rat adipocytes Diabetologia 54 2011 1841 1852
6. J.E. Digby, J. Chen, J.Y. Tang, H. Lehnert, R.N. Matthews, and H.S. Randeva Orexin receptor expression in human adipose tissue: effects of orexin-A and orexin-B J. Endocrinol. 191 2006 129 136
7. K. Zwirska-Korczala Role of leptin, ghrelin, angiotensin II and orexins in 3T3 L1 preadipocyte cells proliferation and oxidative metabolism J. Physiol. Pharmacol. 58 Suppl. 1 2007 53 64
8. M. Skrzypski Neuropeptide B and W regulate leptin and resistin secretion, and stimulate lipolysis in isolated rat adipocytes Regul. Pept. 176 2012 51 56
9. S.C. Martinez, K. Tanabe, C. Cras-Meneur, N.A. Abumrad, E. Bernal-Mizrachi, and M.A. Permutt Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis Diabetes 57 2008 846 859
10. E. Goncz Orexin-A inhibits glucagon secretion and gene expression through a Foxo1-dependent pathway Endocrinology 149 2008 1618 1626
11. A. Bell, A. Gagnon, P. Dods, D. Papineau, M. Tiberi, and A. Sorisky TSH signaling and cell survival in 3T3-L1 preadipocytes Am. J. Physiol. Cell Physiol. 283 2002 C1056 C1064
12. F. Bost, M. Aouadi, L. Caron, and B. Binetruy The role of MAPKs in adipocyte differentiation and obesity Biochimie 87 2005 51 56
13. J.C. Mackall, A.K. Student, S.E. Polakis, and M.D. Lane Induction of lipogenesis during differentiation in a "preadipocyte" cell line J. Biol. Chem. 251 1976 6462 6464
14. H. Miki Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation Mol. Cell. Biol. 21 2001 2521 2532
15. D. El-Chaar, A. Gagnon, and A. Sorisky Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1 Int. J. Obes. Relat. Metab. Disord. 28 2004 191 198
16. M.S. Kim The mitogenic and antiapoptotic actions of ghrelin in 3T3-L1 adipocytes Mol. Endocrinol. 18 2004 2291 2301
17. C.M. Boney, R.M. Smith, and P.A. Gruppuso Modulation of insulin-like growth factor I mitogenic signaling in 3T3-L1 preadipocyte differentiation Endocrinology 139 1998 1638 1644
18. M.K. Kim Angiogenic role of orexin-A via the activation of extracellular signal-regulated kinase in endothelial cells Biochem. Biophys. Res. Commun. 403 2010 59 65
19. M. Ramanjaneya Orexin-stimulated MAP kinase cascades are activated through multiple G-protein signalling pathways in human H295R adrenocortical cells: diverse roles for orexins A and B J. Endocrinol. 202 2009 249 261
20. A. Gagnon, P. Dods, N. Roustan-Delatour, C.S. Chen, and A. Sorisky Phosphatidylinositol-3,4,5-trisphosphate is required for insulin-like growth factor 1-mediated survival of 3T3-L1 preadipocytes Endocrinology 142 2001 205 212
21. H.S. Camp, and S.R. Tafuri Regulation of peroxisome proliferator- activated receptor gamma activity by mitogen-activated protein kinase J. Biol. Chem. 272 1997 10811 10816
22. E. Hu, J.B. Kim, P. Sarraf, and B.M. Spiegelman Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma Science 274 1996 2100 2103
23. D. Prusty, B.H. Park, K.E. Davis, and S.R. Farmer Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator-activated receptor gamma (PPARgamma) and C/EBPalpha gene expression during the differentiation of 3T3-L1 preadipocytes J. Biol. Chem. 277 2002 46226 46232
24. E.M. Sale, P.G. Atkinson, and G.J. Sale Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis EMBO J. 14 1995 674 684
25. P.A. Haridas Nidhina, N. Poulose, and A. Gopalakrishnapillai Vanillin induces adipocyte differentiation in 3T3-L1 cells by activating extracellular signal regulated kinase 42/44 Life Sci. 88 2011 675 680
26. E.D. Rosen, P. Sarraf, A.E. Troy, G. Bradwin, K. Moore, D.S. Milstone, B.M. Spiegelman, and R.M. Mortensen PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro Mol. Cell 4 1999 611 617
27. C.M. Boney, H. Sekimoto, P.A. Gruppuso, and A.R. Frackelton Jr. Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells Cell Growth Differ. 12 2001 379 386
28. L. Rui, V. Aguirre, J.K. Kim, G.I. Shulman, A. Lee, A. Corbould, A. Dunaif, and M.F. White Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways J. Clin. Invest. 107 2001 181 189
29. C.N. Martini, M.V. Plaza, and C. Vila Mdel PKA-dependent and independent cAMP signaling in 3T3-L1 fibroblasts differentiation Mol. Cell. Endocrinol. 298 2009 42 47
30. A. Baudry, Z.Z. Yang, and B.A. Hemmings PKBalpha is required for adipose differentiation of mouse embryonic fibroblasts J. Cell Sci. 119 2006 889 897
31. R. Magun, B.M. Burgering, P.J. Coffer, D. Pardasani, Y. Lin, J. Chabot, and A. Sorisky Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation Endocrinology 137 1996 3590 3593
32. D. Sellayah, P. Bharaj, and D. Sikder Orexin is required for brown adipose tissue development, differentiation, and function Cell Metab. 14 2011 478 490
33. H. Tsuneki Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice Diabetologia 51 2008 657 667
34. H. Funato, A.L. Tsai, J.T. Willie, Y. Kisanuki, S.C. Williams, T. Sakurai, and M. Yanagisawa Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity Cell Metab. 9 2009 64 76
35. J. Hoffstedt Regional impact of adipose tissue morphology on the metabolic profile in morbid obesity Diabetologia 53 2010 2496 2503
36. C.J. de Souza, M. Eckhardt, K. Gagen, M. Dong, W. Chen, D. Laurent, and B.F. Burkey Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance Diabetes 50 2001 1863 1871
37. A. Okuno Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats J. Clin. Invest. 101 1998 1354 1361
38. N. Alkhouri, A. Gornicka, M.P. Berk, S. Thapaliya, L.J. Dixon, S. Kashyap, P.R. Schauer, and A.E. Feldstein Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis J. Biol. Chem. 285 2010 3428 3438
39. K.J. Strissel, Z. Stancheva, H. Miyoshi, J.W. Perfield 2nd, J. DeFuria, Z. Jick, A.S. Greenberg, and M.S. Obin Adipocyte death, adipose tissue remodeling, and obesity complications Diabetes 56 2007 2910 2918