Targeting protein-protein interactions: suppression of Stat3 dimerization with rationally designed small-molecule, nonpeptidic SH2 domain binders.

Chembiochem : a European journal of chemical biology

Volumn 9, Issue 17, 2008, Pages 2800-2803

  Gunning, Patrick T ^a   Glenn, Matthew P ^a   Siddiquee, Khandaker A Z ^a   Katt, William P ^a   Masson, Eric ^a   Sebti, Saïd M ^a   Turkson, James ^a   Hamilton, Andrew D ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; STAT3 PROTEIN;

ANIMAL; ARTICLE; BINDING COMPETITION; BINDING SITE; CELL PROLIFERATION; CELL STRAIN 3T3; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; MOLECULAR LIBRARY; MOUSE; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SRC HOMOLOGY DOMAIN; TUMOR CELL LINE;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; LIGANDS; MICE; MODELS, MOLECULAR; NIH 3T3 CELLS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SMALL MOLECULE LIBRARIES; SRC HOMOLOGY DOMAINS; STAT3 TRANSCRIPTION FACTOR;

EID: 58149392583     PISSN: None     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200800291     Document Type: Article

References (0)