Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 94, Issue 11, 2012, Pages 934-942

  Leslie, Elizabeth J ^a   Mansilla, M Adela ^a   Biggs, Leah C ^a   Schuette, Kristi ^a   Bullard, Steve ^b   Cooper, Margaret ^c   Dunnwald, Martine ^a   Lidral, Andrew C ^b   Marazita, Mary L ^c   Beaty, Terri H ^d   Murray, Jeffrey C ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

ARHGAP29; Candidate gene; Cleft lip and palate; Complex traits; Rho signaling

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 6; RHO GTPASE ACTIVATING PROTEIN 29; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHROMOSOME 1P; CLEFT LIP; CLEFT PALATE; CONTROLLED STUDY; EXON; FRAMESHIFT MUTATION; GENE DELETION; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; HUMAN; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; NONSENSE MUTATION; PRIORITY JOURNAL;

ANIMALS; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 1; CLEFT LIP; CLEFT PALATE; DNA MUTATIONAL ANALYSIS; EMBRYO, MAMMALIAN; EXONS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; GTPASE-ACTIVATING PROTEINS; HUMANS; INTERFERON REGULATORY FACTORS; MICE; MUTATION; PHILIPPINES; SIGNAL TRANSDUCTION; UNITED STATES;

MURINAE;

EID: 84869449975     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.23076     Document Type: Article

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