메뉴 건너뛰기




Volumn 34, Issue 3, 2011, Pages 303-314

RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; TRANSCRIPTION FACTOR RUNX;

EID: 79952750496     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.03.004     Document Type: Article
Times cited : (29)

References (51)
  • 3
    • 0033083793 scopus 로고    scopus 로고
    • Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
    • Brown K.E., Baxter J., Graf D., Merkenschlager M., Fisher A.G. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol. Cell 1999, 3:207-217.
    • (1999) Mol. Cell , vol.3 , pp. 207-217
    • Brown, K.E.1    Baxter, J.2    Graf, D.3    Merkenschlager, M.4    Fisher, A.G.5
  • 5
    • 2442695407 scopus 로고    scopus 로고
    • Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription
    • Chambeyron S., Bickmore W.A. Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes Dev. 2004, 18:1119-1130.
    • (2004) Genes Dev. , vol.18 , pp. 1119-1130
    • Chambeyron, S.1    Bickmore, W.A.2
  • 6
    • 77950484789 scopus 로고    scopus 로고
    • Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells
    • Chong M.M., Simpson N., Ciofani M., Chen G., Collins A., Littman D.R. Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. Genes Dev. 2010, 24:659-669.
    • (2010) Genes Dev. , vol.24 , pp. 659-669
    • Chong, M.M.1    Simpson, N.2    Ciofani, M.3    Chen, G.4    Collins, A.5    Littman, D.R.6
  • 7
    • 33646591544 scopus 로고    scopus 로고
    • Transcriptional pulsing of a developmental gene
    • Chubb J.R., Trcek T., Shenoy S.M., Singer R.H. Transcriptional pulsing of a developmental gene. Curr. Biol. 2006, 16:1018-1025.
    • (2006) Curr. Biol. , vol.16 , pp. 1018-1025
    • Chubb, J.R.1    Trcek, T.2    Shenoy, S.M.3    Singer, R.H.4
  • 8
    • 58849086223 scopus 로고    scopus 로고
    • RUNX proteins in transcription factor networks that regulate T-cell lineage choice
    • Collins A., Littman D.R., Taniuchi I. RUNX proteins in transcription factor networks that regulate T-cell lineage choice. Nat. Rev. Immunol. 2009, 9:106-115.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 106-115
    • Collins, A.1    Littman, D.R.2    Taniuchi, I.3
  • 9
    • 0032493380 scopus 로고    scopus 로고
    • HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells
    • Dave V.P., Allman D., Keefe R., Hardy R.R., Kappes D.J. HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells. Proc. Natl. Acad. Sci. USA 1998, 95:8187-8192.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8187-8192
    • Dave, V.P.1    Allman, D.2    Keefe, R.3    Hardy, R.R.4    Kappes, D.J.5
  • 10
    • 10644289346 scopus 로고    scopus 로고
    • Dynamic repositioning of CD4 and CD8 genes during T cell development
    • Delaire S., Huang Y.H., Chan S.W., Robey E.A. Dynamic repositioning of CD4 and CD8 genes during T cell development. J. Exp. Med. 2004, 200:1427-1435.
    • (2004) J. Exp. Med. , vol.200 , pp. 1427-1435
    • Delaire, S.1    Huang, Y.H.2    Chan, S.W.3    Robey, E.A.4
  • 11
    • 52549101132 scopus 로고    scopus 로고
    • ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage
    • Egawa T., Littman D.R. ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage. Nat. Immunol. 2008, 9:1131-1139.
    • (2008) Nat. Immunol. , vol.9 , pp. 1131-1139
    • Egawa, T.1    Littman, D.R.2
  • 12
    • 34547744867 scopus 로고    scopus 로고
    • The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells
    • Egawa T., Tillman R.E., Naoe Y., Taniuchi I., Littman D.R. The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells. J. Exp. Med. 2007, 204:1945-1957.
    • (2007) J. Exp. Med. , vol.204 , pp. 1945-1957
    • Egawa, T.1    Tillman, R.E.2    Naoe, Y.3    Taniuchi, I.4    Littman, D.R.5
  • 13
    • 0030670312 scopus 로고    scopus 로고
    • An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells
    • Ellmeier W., Sunshine M.J., Losos K., Hatam F., Littman D.R. An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells. Immunity 1997, 7:537-547.
    • (1997) Immunity , vol.7 , pp. 537-547
    • Ellmeier, W.1    Sunshine, M.J.2    Losos, K.3    Hatam, F.4    Littman, D.R.5
  • 14
    • 0032191963 scopus 로고    scopus 로고
    • Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells
    • Ellmeier W., Sunshine M.J., Losos K., Littman D.R. Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells. Immunity 1998, 9:485-496.
    • (1998) Immunity , vol.9 , pp. 485-496
    • Ellmeier, W.1    Sunshine, M.J.2    Losos, K.3    Littman, D.R.4
  • 15
    • 0036285006 scopus 로고    scopus 로고
    • Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression
    • Ellmeier W., Sunshine M.J., Maschek R., Littman D.R. Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression. Immunity 2002, 16:623-634.
    • (2002) Immunity , vol.16 , pp. 623-634
    • Ellmeier, W.1    Sunshine, M.J.2    Maschek, R.3    Littman, D.R.4
  • 16
    • 34249307315 scopus 로고    scopus 로고
    • Nuclear organization of the genome and the potential for gene regulation
    • Fraser P., Bickmore W. Nuclear organization of the genome and the potential for gene regulation. Nature 2007, 447:413-417.
    • (2007) Nature , vol.447 , pp. 413-417
    • Fraser, P.1    Bickmore, W.2
  • 17
    • 14544288635 scopus 로고    scopus 로고
    • The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
    • He X., He X., Dave V.P., Zhang Y., Hua X., Nicolas E., Xu W., Roe B.A., Kappes D.J. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 2005, 433:826-833.
    • (2005) Nature , vol.433 , pp. 826-833
    • He, X.1    He, X.2    Dave, V.P.3    Zhang, Y.4    Hua, X.5    Nicolas, E.6    Xu, W.7    Roe, B.A.8    Kappes, D.J.9
  • 18
    • 40949152727 scopus 로고    scopus 로고
    • Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells
    • Hewitt S.L., Farmer D., Marszalek K., Cadera E., Liang H.E., Xu Y., Schlissel M.S., Skok J.A. Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells. Nat. Immunol. 2008, 9:396-404.
    • (2008) Nat. Immunol. , vol.9 , pp. 396-404
    • Hewitt, S.L.1    Farmer, D.2    Marszalek, K.3    Cadera, E.4    Liang, H.E.5    Xu, Y.6    Schlissel, M.S.7    Skok, J.A.8
  • 20
    • 0030725991 scopus 로고    scopus 로고
    • A region in the CD8 gene locus that directs expression to the mature CD8 T cell subset in transgenic mice
    • Hostert A., Tolaini M., Roderick K., Harker N., Norton T., Kioussis D. A region in the CD8 gene locus that directs expression to the mature CD8 T cell subset in transgenic mice. Immunity 1997, 7:525-536.
    • (1997) Immunity , vol.7 , pp. 525-536
    • Hostert, A.1    Tolaini, M.2    Roderick, K.3    Harker, N.4    Norton, T.5    Kioussis, D.6
  • 22
    • 0029973080 scopus 로고    scopus 로고
    • Active RNA polymerases are localized within discrete transcription " factories" in human nuclei
    • Iborra F.J., Pombo A., Jackson D.A., Cook P.R. Active RNA polymerases are localized within discrete transcription " factories" in human nuclei. J. Cell Sci. 1996, 109:1427-1436.
    • (1996) J. Cell Sci. , vol.109 , pp. 1427-1436
    • Iborra, F.J.1    Pombo, A.2    Jackson, D.A.3    Cook, P.R.4
  • 23
    • 33847153126 scopus 로고    scopus 로고
    • Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation
    • Jenkinson S.R., Intlekofer A.M., Sun G., Feigenbaum L., Reiner S.L., Bosselut R. Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. J. Exp. Med. 2007, 204:267-272.
    • (2007) J. Exp. Med. , vol.204 , pp. 267-272
    • Jenkinson, S.R.1    Intlekofer, A.M.2    Sun, G.3    Feigenbaum, L.4    Reiner, S.L.5    Bosselut, R.6
  • 24
    • 0036885036 scopus 로고    scopus 로고
    • Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation
    • Kioussis D., Ellmeier W. Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation. Nat. Rev. Immunol. 2002, 2:909-919.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 909-919
    • Kioussis, D.1    Ellmeier, W.2
  • 25
    • 31444439049 scopus 로고    scopus 로고
    • A role for Runx transcription factor signaling in dorsal root ganglion sensory neuron diversification
    • Kramer I., Sigrist M., de Nooij J.C., Taniuchi I., Jessell T.M., Arber S. A role for Runx transcription factor signaling in dorsal root ganglion sensory neuron diversification. Neuron 2006, 49:379-393.
    • (2006) Neuron , vol.49 , pp. 379-393
    • Kramer, I.1    Sigrist, M.2    de Nooij, J.C.3    Taniuchi, I.4    Jessell, T.M.5    Arber, S.6
  • 28
    • 0022326959 scopus 로고
    • Regulation of the genes of the bithorax complex in Drosophila
    • Lewis E.B. Regulation of the genes of the bithorax complex in Drosophila. Cold Spring Harb. Symp. Quant. Biol. 1985, 50:155-164.
    • (1985) Cold Spring Harb. Symp. Quant. Biol. , vol.50 , pp. 155-164
    • Lewis, E.B.1
  • 29
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
    • Manel N., Unutmaz D., Littman D.R. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat. Immunol. 2008, 9:641-649.
    • (2008) Nat. Immunol. , vol.9 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 30
    • 84941871856 scopus 로고
    • The Kolmogorov-Smirnov test for goodness of fit
    • Massey F.J. The Kolmogorov-Smirnov test for goodness of fit. J. Am. Stat. Assoc. 1951, 253:1951.
    • (1951) J. Am. Stat. Assoc. , vol.253 , pp. 1951
    • Massey, F.J.1
  • 31
    • 10644253554 scopus 로고    scopus 로고
    • Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice
    • Merkenschlager M., Amoils S., Roldan E., Rahemtulla A., O'connor E., Fisher A.G., Brown K.E. Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice. J. Exp. Med. 2004, 200:1437-1444.
    • (2004) J. Exp. Med. , vol.200 , pp. 1437-1444
    • Merkenschlager, M.1    Amoils, S.2    Roldan, E.3    Rahemtulla, A.4    O'connor, E.5    Fisher, A.G.6    Brown, K.E.7
  • 35
    • 33744779614 scopus 로고    scopus 로고
    • The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation
    • Ragoczy T., Bender M.A., Telling A., Byron R., Groudine M. The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. Genes Dev. 2006, 20:1447-1457.
    • (2006) Genes Dev. , vol.20 , pp. 1447-1457
    • Ragoczy, T.1    Bender, M.A.2    Telling, A.3    Byron, R.4    Groudine, M.5
  • 36
    • 12344270023 scopus 로고    scopus 로고
    • Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene
    • Roldán E., Fuxa M., Chong W., Martinez D., Novatchkova M., Busslinger M., Skok J.A. Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. Nat. Immunol. 2005, 6:31-41.
    • (2005) Nat. Immunol. , vol.6 , pp. 31-41
    • Roldán, E.1    Fuxa, M.2    Chong, W.3    Martinez, D.4    Novatchkova, M.5    Busslinger, M.6    Skok, J.A.7
  • 37
    • 15244342946 scopus 로고    scopus 로고
    • Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes
    • Sato T., Ohno S., Hayashi T., Sato C., Kohu K., Satake M., Habu S. Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes. Immunity 2005, 22:317-328.
    • (2005) Immunity , vol.22 , pp. 317-328
    • Sato, T.1    Ohno, S.2    Hayashi, T.3    Sato, C.4    Kohu, K.5    Satake, M.6    Habu, S.7
  • 38
    • 0028242609 scopus 로고
    • A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development
    • Sawada S., Scarborough J.D., Killeen N., Littman D.R. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 1994, 77:917-929.
    • (1994) Cell , vol.77 , pp. 917-929
    • Sawada, S.1    Scarborough, J.D.2    Killeen, N.3    Littman, D.R.4
  • 39
    • 13244275244 scopus 로고    scopus 로고
    • Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells
    • Sayegh C.E., Jhunjhunwala S., Riblet R., Murre C. Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. Genes Dev. 2005, 19:322-327.
    • (2005) Genes Dev. , vol.19 , pp. 322-327
    • Sayegh, C.E.1    Jhunjhunwala, S.2    Riblet, R.3    Murre, C.4
  • 43
    • 20444494936 scopus 로고    scopus 로고
    • Interchromosomal associations between alternatively expressed loci
    • Spilianakis C.G., Lalioti M.D., Town T., Lee G.R., Flavell R.A. Interchromosomal associations between alternatively expressed loci. Nature 2005, 435:637-645.
    • (2005) Nature , vol.435 , pp. 637-645
    • Spilianakis, C.G.1    Lalioti, M.D.2    Town, T.3    Lee, G.R.4    Flavell, R.A.5
  • 44
    • 68549130681 scopus 로고    scopus 로고
    • Paramutation: A heritable change in gene expression by allelic interactions in trans
    • Stam M. Paramutation: A heritable change in gene expression by allelic interactions in trans. Mol Plant 2009, 2:578-588.
    • (2009) Mol Plant , vol.2 , pp. 578-588
    • Stam, M.1
  • 47
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • Taniuchi I., Osato M., Egawa T., Sunshine M.J., Bae S.C., Komori T., Ito Y., Littman D.R. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 2002, 111:621-633.
    • (2002) Cell , vol.111 , pp. 621-633
    • Taniuchi, I.1    Osato, M.2    Egawa, T.3    Sunshine, M.J.4    Bae, S.C.5    Komori, T.6    Ito, Y.7    Littman, D.R.8
  • 48
    • 0036864610 scopus 로고    scopus 로고
    • Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation
    • Taniuchi I., Sunshine M.J., Festenstein R., Littman D.R. Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation. Mol. Cell 2002, 10:1083-1096.
    • (2002) Mol. Cell , vol.10 , pp. 1083-1096
    • Taniuchi, I.1    Sunshine, M.J.2    Festenstein, R.3    Littman, D.R.4
  • 49
    • 38949192274 scopus 로고    scopus 로고
    • The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer
    • Wildt K.F., Sun G., Grueter B., Fischer M., Zamisch M., Ehlers M., Bosselut R. The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer. J. Immunol. 2007, 179:4405-4414.
    • (2007) J. Immunol. , vol.179 , pp. 4405-4414
    • Wildt, K.F.1    Sun, G.2    Grueter, B.3    Fischer, M.4    Zamisch, M.5    Ehlers, M.6    Bosselut, R.7
  • 50
    • 33644557773 scopus 로고    scopus 로고
    • Transient homologous chromosome pairing marks the onset of X inactivation
    • Xu N., Tsai C.L., Lee J.T. Transient homologous chromosome pairing marks the onset of X inactivation. Science 2006, 311:1149-1152.
    • (2006) Science , vol.311 , pp. 1149-1152
    • Xu, N.1    Tsai, C.L.2    Lee, J.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.