All-trans retinoic acid combined with 5-Aza-2'-deoxycitidine induces C/EBPα expression and growth inhibition in MLL-AF9-positive leukemic cells

Biochemical and Biophysical Research Communications

Volumn 428, Issue 2, 2012, Pages 216-223

  Fujiki, Atsushi ^a   Imamura, Toshihiko ^a   Sakamoto, Kenichi ^a   Kawashima, Sachiko ^a   Yoshida, Hideki ^a   Hirashima, Yoshifumi ^a   Miyachi, Mitsuru ^a   Yagyu, Shigeki ^a   Nakatani, Takuya ^a   Sugita, Kanji ^b   Hosoi, Hajime ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

5 Aza 2' deoxycytidine; Acute myeloid leukemia; All trans retinoic acid; CCAAT enhancer binding protein alpha; MLL rearrangement; Retinoic acid pathway

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN EPSILON; HYBRID PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; RETINOIC ACID; TRANSCRIPTION FACTOR PU 1;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG SENSITIVITY; EPIGENETICS; GENE INACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; AZACITIDINE; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL LINE, TUMOR; CELL PROLIFERATION; DNA METHYLATION; DRUG RESISTANCE, NEOPLASM; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; TRETINOIN;

MURINAE;

EID: 84869212088     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.09.131     Document Type: Article

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