Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia

American Journal of Pathology

Volumn 181, Issue 6, 2012, Pages 2114-2125

  Syu, Li Jyun ^a   El Zaatari, Mohamad ^a   Eaton, Kathryn A ^a   Liu, Zhiping ^a   Tetarbe, Manas ^a   Keeley, Theresa M ^a   Pero, Joanna ^a   Ferris, Jennifer ^a   Wilbert, Dawn ^a   Kaatz, Ashley ^a   Zheng, Xinlei ^a   Qiao, Xiotan ^a   Grachtchouk, Marina ^a   Gumucio, Deborah L ^a   Merchant, Juanita L ^a   Samuelson, Linda C ^a   Dlugosz, Andrzej A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BETA CATENIN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; STAT1 PROTEIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL EXPANSION; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; DYSPLASIA; EPITHELIUM CELL; GASTRITIS; GENE EXPRESSION; GENE TARGETING; METAPLASIA; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA; STOMACH ADENOMA; STOMACH ANTRUM; STOMACH CHIEF CELL; STOMACH PARIETAL CELL; STOMACH POLYP; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; ATROPHY; CELL LINEAGE; CELL PROLIFERATION; DISEASE PROGRESSION; FEMALE; H(+)-K(+)-EXCHANGING ATPASE; HEDGEHOG PROTEINS; INFLAMMATION; INTERFERON-GAMMA; MALE; METAPLASIA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGAN SIZE; PARIETAL CELLS, GASTRIC; PEPTIDES; PRECANCEROUS CONDITIONS; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; STOMACH; STOMACH NEOPLASMS; UP-REGULATION;

EID: 84869195346     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.08.017     Document Type: Article

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