-
1
-
-
0029043658
-
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach
-
Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995;55:2111-2115.
-
(1995)
Cancer Res
, vol.55
, pp. 2111-2115
-
-
Blaser, M.J.1
Perez-Perez, G.I.2
Kleanthous, H.3
Cover, T.L.4
Peek, R.M.5
Chyou, P.H.6
-
2
-
-
0034042694
-
Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus
-
Backert S, Ziska E, Brinkmann V, Zimny-Arndt U, Fauconnier A, Jungblut PR, et al. Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus. Cell Microbiol 2000;2:155-164.
-
(2000)
Cell Microbiol
, vol.2
, pp. 155-164
-
-
Backert, S.1
Ziska, E.2
Brinkmann, V.3
Zimny-Arndt, U.4
Fauconnier, A.5
Jungblut, P.R.6
-
3
-
-
0036510363
-
Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo
-
Selbach M, Moese S, Hauck CR, Meyer TF, Backert S. Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J Biol Chem 2002;277:6775-6778.
-
(2002)
J Biol Chem
, vol.277
, pp. 6775-6778
-
-
Selbach, M.1
Moese, S.2
Hauck, C.R.3
Meyer, T.F.4
Backert, S.5
-
4
-
-
0037169076
-
SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein
-
Higashi H, Tsutsumi R, Muto S, Sugiyama T, Azuma T, Asaka M, et al. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science 2002;295:683-686.
-
(2002)
Science
, vol.295
, pp. 683-686
-
-
Higashi, H.1
Tsutsumi, R.2
Muto, S.3
Sugiyama, T.4
Azuma, T.5
Asaka, M.6
-
5
-
-
0034717029
-
Helicobacter pylori activates mitogen-activated protein kinase cascades and induces expression of the proto-oncogenes c-fos and c-jun
-
Meyer-ter-Vehn T, Covacci A, Kist M, Pahl HL. Helicobacter pylori activates mitogen-activated protein kinase cascades and induces expression of the proto-oncogenes c-fos and c-jun. J Biol Chem 2000;275:16064- 16072.
-
(2000)
J Biol Chem
, vol.275
, pp. 16064-16072
-
-
Meyer-ter-Vehn, T.1
Covacci, A.2
Kist, M.3
Pahl, H.L.4
-
6
-
-
2342429370
-
Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation
-
Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, et al. Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation. J Biol Chem 2004;279:17205-17216.
-
(2004)
J Biol Chem
, vol.279
, pp. 17205-17216
-
-
Higashi, H.1
Nakaya, A.2
Tsutsumi, R.3
Yokoyama, K.4
Fujii, Y.5
Ishikawa, S.6
-
7
-
-
9144249648
-
Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130
-
Judd LM, Alderman BM, Howlett M, Shulkes A, Dow C, Moverley J, et al. Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130. Gastroenterology 2004;126:196-207.
-
(2004)
Gastroenterology
, vol.126
, pp. 196-207
-
-
Judd, L.M.1
Alderman, B.M.2
Howlett, M.3
Shulkes, A.4
Dow, C.5
Moverley, J.6
-
8
-
-
0036796060
-
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
-
Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ, et al. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nature Med 2002;8:1089-1097.
-
(2002)
Nature Med
, vol.8
, pp. 1089-1097
-
-
Tebbutt, N.C.1
Giraud, A.S.2
Inglese, M.3
Jenkins, B.4
Waring, P.5
Clay, F.J.6
-
9
-
-
33749328700
-
STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis
-
Judd LM, Bredin K, Kalantzis A, Jenkins BJ, Ernst M, Giraud AS. STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis. Gastroenterology 2006;131:1073-1085.
-
(2006)
Gastroenterology
, vol.131
, pp. 1073-1085
-
-
Judd, L.M.1
Bredin, K.2
Kalantzis, A.3
Jenkins, B.J.4
Ernst, M.5
Giraud, A.S.6
-
10
-
-
23844445451
-
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling
-
Jenkins BJ, Grail D, Nheu T, Najdovska M, Wang B, Waring P, et al. Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. Nature Med 2005;11:845-852.
-
(2005)
Nature Med
, vol.11
, pp. 845-852
-
-
Jenkins, B.J.1
Grail, D.2
Nheu, T.3
Najdovska, M.4
Wang, B.5
Waring, P.6
-
11
-
-
0036251154
-
Stat proteins and oncogenesis
-
Bromberg J. Stat proteins and oncogenesis. J Clin Invest 2002;109:1139-1142.
-
(2002)
J Clin Invest
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
12
-
-
0037444373
-
Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
-
Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, Sebti SM. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Res 2003;63:1270-1279.
-
(2003)
Cancer Res
, vol.63
, pp. 1270-1279
-
-
Blaskovich, M.A.1
Sun, J.2
Cantor, A.3
Turkson, J.4
Jove, R.5
Sebti, S.M.6
-
13
-
-
85047698100
-
Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells
-
Burke WM, Jin X, Lin HJ, Huang M, Liu R, Reynolds RK, et al. Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells. Oncogene 2001;20:7925-7934.
-
(2001)
Oncogene
, vol.20
, pp. 7925-7934
-
-
Burke, W.M.1
Jin, X.2
Lin, H.J.3
Huang, M.4
Liu, R.5
Reynolds, R.K.6
-
14
-
-
0037112367
-
Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
-
Mora LB, Buettner R, Seigne J, Diaz J, Ahmad N, Garcia R, et al. Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res 2002;62:6659-6666.
-
(2002)
Cancer Res
, vol.62
, pp. 6659-6666
-
-
Mora, L.B.1
Buettner, R.2
Seigne, J.3
Diaz, J.4
Ahmad, N.5
Garcia, R.6
-
15
-
-
22044437986
-
Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth
-
Corvinus FM, Orth C, Moriggl R, Tsareva SA, Wagner S, Pfitzner EB, et al. Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia 2005;7:545-555.
-
(2005)
Neoplasia
, vol.7
, pp. 545-555
-
-
Corvinus, F.M.1
Orth, C.2
Moriggl, R.3
Tsareva, S.A.4
Wagner, S.5
Pfitzner, E.B.6
-
16
-
-
3042726888
-
STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells
-
Kanda N, Seno H, Konda Y, Marusawa H, Kanai M, Nakajima T, et al. STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells. Oncogene 2004;23:4921-4929.
-
(2004)
Oncogene
, vol.23
, pp. 4921-4929
-
-
Kanda, N.1
Seno, H.2
Konda, Y.3
Marusawa, H.4
Kanai, M.5
Nakajima, T.6
-
17
-
-
0038576352
-
Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer
-
Boussioutas A, Li H, Liu J, Waring P, Lade S, Holloway AJ, et al. Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer. Cancer Res 2003;63:2569-2577.
-
(2003)
Cancer Res
, vol.63
, pp. 2569-2577
-
-
Boussioutas, A.1
Li, H.2
Liu, J.3
Waring, P.4
Lade, S.5
Holloway, A.J.6
-
18
-
-
31544460919
-
Topological and functional discovery in a gene coexpression meta-network of gastric cancer
-
Aggarwal A, Guo DL, Hoshida Y, Yuen ST, Chu KM, So S, et al. Topological and functional discovery in a gene coexpression meta-network of gastric cancer. Cancer Res 2006;66:232-241.
-
(2006)
Cancer Res
, vol.66
, pp. 232-241
-
-
Aggarwal, A.1
Guo, D.L.2
Hoshida, Y.3
Yuen, S.T.4
Chu, K.M.5
So, S.6
-
19
-
-
0037439278
-
The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa
-
Yamazaki S, Yamakawa A, Ito Y, Ohtani M, Higashi H, Hatakeyama M, et al. The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa. J Infect Dis 2003;187:334-337.
-
(2003)
J Infect Dis
, vol.187
, pp. 334-337
-
-
Yamazaki, S.1
Yamakawa, A.2
Ito, Y.3
Ohtani, M.4
Higashi, H.5
Hatakeyama, M.6
-
20
-
-
0031888837
-
Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells
-
Kim H, Hawley TS, Hawley RG, Baumann H. Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells. Mol Cell Biol 1998;18:1525-1533.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1525-1533
-
-
Kim, H.1
Hawley, T.S.2
Hawley, R.G.3
Baumann, H.4
-
21
-
-
0033571334
-
Differential activation of mitogen-activated protein kinases in AGS gastric epithelial cells by cag+ and cag-Helicobacter pylori
-
Keates S, Keates AC, Warny M, Peek RM Jr, Murray PG, Kelly CP. Differential activation of mitogen-activated protein kinases in AGS gastric epithelial cells by cag+ and cag-Helicobacter pylori. J Immunol 1999;163:5552-5559.
-
(1999)
J Immunol
, vol.163
, pp. 5552-5559
-
-
Keates, S.1
Keates, A.C.2
Warny, M.3
Peek Jr, R.M.4
Murray, P.G.5
Kelly, C.P.6
-
22
-
-
0027518383
-
Gastric interleukin-8 and IgA IL-8 autoantibodies in Helicobacter pylori infection
-
Crabtree JE, Peichl P, Wyatt JJ, Stachl U, Lindley IJ. Gastric interleukin-8 and IgA IL-8 autoantibodies in Helicobacter pylori infection. Scand J Immunol 1993;37:65-70.
-
(1993)
Scand J Immunol
, vol.37
, pp. 65-70
-
-
Crabtree, J.E.1
Peichl, P.2
Wyatt, J.J.3
Stachl, U.4
Lindley, I.J.5
-
23
-
-
1842426688
-
Role of interferon-stimulated responsive element-like element in interleukin-8 promoter in Helicobacter pylori infection
-
Yamaoka Y, Kudo T, Lu H, Casola A, Brasier AR, Graham DY. Role of interferon-stimulated responsive element-like element in interleukin-8 promoter in Helicobacter pylori infection. Gastroenterology 2004;126:1030-1043.
-
(2004)
Gastroenterology
, vol.126
, pp. 1030-1043
-
-
Yamaoka, Y.1
Kudo, T.2
Lu, H.3
Casola, A.4
Brasier, A.R.5
Graham, D.Y.6
-
24
-
-
0030046753
-
-
Ihle JN. STATs: signal transducers and activators of transcription. Cell 1996;84:331-334.
-
Ihle JN. STATs: signal transducers and activators of transcription. Cell 1996;84:331-334.
-
-
-
-
25
-
-
1542297244
-
IL-6 signal transduction and its physiological roles: The signal orchestration model
-
Kamimura D, Ishihara K, Hirano T. IL-6 signal transduction and its physiological roles: the signal orchestration model. Rev Physiol Biochem Pharmacol 2003;149:1-38.
-
(2003)
Rev Physiol Biochem Pharmacol
, vol.149
, pp. 1-38
-
-
Kamimura, D.1
Ishihara, K.2
Hirano, T.3
-
26
-
-
0033535958
-
Autoregulation of pituitary corticotroph SOCS-3 expression: Characterization of the murine SOCS-3 promoter
-
Auernhammer CJ, Bousquet C, Melmed S. Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter. Proc Natl Acad Sci U S A 1999;96:6964-6969.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 6964-6969
-
-
Auernhammer, C.J.1
Bousquet, C.2
Melmed, S.3
-
27
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nature Immunol 2004;5:1166- 1174.
-
(2004)
Nature Immunol
, vol.5
, pp. 1166-1174
-
-
Viala, J.1
Chaput, C.2
Boneca, I.G.3
Cardona, A.4
Girardin, S.E.5
Moran, A.P.6
-
28
-
-
33646591224
-
Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation
-
Nadiminty N, Lou W, Lee SO, Lin X, Trump DL, Gao AC. Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation. Proc Natl Acad Sci U S A 2006;103:7264-7269.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7264-7269
-
-
Nadiminty, N.1
Lou, W.2
Lee, S.O.3
Lin, X.4
Trump, D.L.5
Gao, A.C.6
-
29
-
-
0031771563
-
Local cytokine response in Helicobacter pylori-infected subjects
-
Lindholm C, Quiding-Jarbrink M, Lonroth H, Hamlet A, Svennerholm AM. Local cytokine response in Helicobacter pylori-infected subjects. Infect Immun 1998;66:5964-5971.
-
(1998)
Infect Immun
, vol.66
, pp. 5964-5971
-
-
Lindholm, C.1
Quiding-Jarbrink, M.2
Lonroth, H.3
Hamlet, A.4
Svennerholm, A.M.5
-
30
-
-
0030772159
-
Helicobacter pylori infection activates NF-kappa B in gastric epithelial cells
-
Keates S, Hitti YS, Upton M, Kelly CP. Helicobacter pylori infection activates NF-kappa B in gastric epithelial cells. Gastroenterology 1997;113:1099-1109.
-
(1997)
Gastroenterology
, vol.113
, pp. 1099-1109
-
-
Keates, S.1
Hitti, Y.S.2
Upton, M.3
Kelly, C.P.4
-
31
-
-
15944393178
-
The survival of IL-6-dependent myeloma cells critically relies on their capability to transit the G1 to S phase interval of the cell cycle
-
Cote S, Lemieux R, Simard C. The survival of IL-6-dependent myeloma cells critically relies on their capability to transit the G1 to S phase interval of the cell cycle. Cell Signal 2005;17:615-624.
-
(2005)
Cell Signal
, vol.17
, pp. 615-624
-
-
Cote, S.1
Lemieux, R.2
Simard, C.3
-
32
-
-
0036912873
-
Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma
-
Huang SP, Wu MS, Wang HP, Yang CS, Kuo ML, Lin JT. Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma. J Gastroenterol Hepatol 2002;17:1165-1169.
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 1165-1169
-
-
Huang, S.P.1
Wu, M.S.2
Wang, H.P.3
Yang, C.S.4
Kuo, M.L.5
Lin, J.T.6
-
33
-
-
0034952052
-
Relation between cytokines and Helicobacter pylori in gastric cancer
-
Yamaoka Y, Kodama T, Kita M, Imanishi J, Kashima K, Graham DY. Relation between cytokines and Helicobacter pylori in gastric cancer. Helicobacter 2001;6:116-124.
-
(2001)
Helicobacter
, vol.6
, pp. 116-124
-
-
Yamaoka, Y.1
Kodama, T.2
Kita, M.3
Imanishi, J.4
Kashima, K.5
Graham, D.Y.6
-
34
-
-
23944436914
-
Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation
-
Franic TV, van Driel IR, Gleeson PA, Giraud AS, Judd LM. Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation. J Pathol 2005;207:43-52.
-
(2005)
J Pathol
, vol.207
, pp. 43-52
-
-
Franic, T.V.1
van Driel, I.R.2
Gleeson, P.A.3
Giraud, A.S.4
Judd, L.M.5
-
35
-
-
0037052686
-
Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats
-
Wen CY, Ito M, Matsuu M, Fukuda E, Shichijo K, Nakashima M, et al. Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. Life Sci 2002;70:2997-3005.
-
(2002)
Life Sci
, vol.70
, pp. 2997-3005
-
-
Wen, C.Y.1
Ito, M.2
Matsuu, M.3
Fukuda, E.4
Shichijo, K.5
Nakashima, M.6
-
36
-
-
0030006884
-
Interleukin-11 prevents apoptosis and accelerates recovery of small intestinal mucosa in mice treated with combined chemotherapy and radiation
-
Orazi A, Du X, Yang Z, Kashai M, Williams DA. Interleukin-11 prevents apoptosis and accelerates recovery of small intestinal mucosa in mice treated with combined chemotherapy and radiation. Lab Invest 1996;75:33- 42.
-
(1996)
Lab Invest
, vol.75
, pp. 33-42
-
-
Orazi, A.1
Du, X.2
Yang, Z.3
Kashai, M.4
Williams, D.A.5
-
37
-
-
34247855977
-
Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the invasive activity of human gastric carcinoma cells
-
Nakayama T, Yoshizaki A, Izumida S, Suehiro T, Miura S, Uemura T, et al. Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the invasive activity of human gastric carcinoma cells. Int J Oncol 2007;30:825-833.
-
(2007)
Int J Oncol
, vol.30
, pp. 825-833
-
-
Nakayama, T.1
Yoshizaki, A.2
Izumida, S.3
Suehiro, T.4
Miura, S.5
Uemura, T.6
-
38
-
-
33749243597
-
Identification of protein expression signatures associated with Helicobacter pylori infection and gastric adenocarcinoma using recombinant antibody microarrays
-
Ellmark P, Ingvarsson J, Carlsson A, Lundin BS, Wingren C, Borrebaeck CA. Identification of protein expression signatures associated with Helicobacter pylori infection and gastric adenocarcinoma using recombinant antibody microarrays. Mol Cell Proteomics 2006;5:1638-1646.
-
(2006)
Mol Cell Proteomics
, vol.5
, pp. 1638-1646
-
-
Ellmark, P.1
Ingvarsson, J.2
Carlsson, A.3
Lundin, B.S.4
Wingren, C.5
Borrebaeck, C.A.6
-
39
-
-
2142815242
-
The evolving epidemiology of Helicobacter pylori infection and gastric cancer
-
Huang JQ, Hunt RH. The evolving epidemiology of Helicobacter pylori infection and gastric cancer. Can J Gastroenterol 2003;17(Suppl B):18B-20B.
-
(2003)
Can J Gastroenterol
, vol.17
, Issue.SUPPL. B
-
-
Huang, J.Q.1
Hunt, R.H.2
-
40
-
-
12944272024
-
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
-
Grandis JR, Drenning SD, Zeng Q, Watkins SC, Melhem MF, Endo S, et al. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc Natl Acad Sci U S A 2000;97:4227-4232.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4227-4232
-
-
Grandis, J.R.1
Drenning, S.D.2
Zeng, Q.3
Watkins, S.C.4
Melhem, M.F.5
Endo, S.6
|